CD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis.

abstract：:Precise mitotic spindle orientation is essential for both cell fate and tissue organization while defects in this process are associated with tumorigenesis and other diseases. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral microtubules to position...

journal_title：Scientific reports

authors： Vodicska B,Cerikan B,Schiebel E,Hoffmann I

更新日期：2018-04-20 00:00:00

abstract：:Overuse of antibiotics has caused serious problems, such as appearance of super bacteria, whose accumulation in the human body through the food chain is a concern. Kanamycin is a common antibiotic used to treat diverse infections; however, residual kanamycin can cause many side effects in humans. Thus, development of ...

journal_title：Scientific reports

authors： Ha NR,Jung IP,La IJ,Jung HS,Yoon MY

更新日期：2017-01-05 00:00:00

abstract：:We have studied the intrinsic fluorescence spectra of a monomeric variant of human transthyretin (M-TTR), a protein involved in the transport of the thyroid hormone and retinol and associated with various forms of amyloidosis, extending our analysis to the second order derivative of the spectra. This procedure allowed...

journal_title：Scientific reports

authors： Jazaj D,Ghadami SA,Bemporad F,Chiti F

更新日期：2019-07-29 00:00:00

abstract：:Protein kinases are enzymes whose abundance, protein-protein interactions, and posttranslational modifications together determine net signaling activity in cells. Large-scale data on cellular kinase activity are limited, because existing assays are cumbersome, poorly sensitive, low throughput, and restricted to measur...

journal_title：Scientific reports

authors： Smolko CM,Janes KA

更新日期：2019-12-19 00:00:00

abstract：:The mitogen-activated protein kinase (MAPK)-mediated phosphorylation cascade is a vital component of plant cellular signalling. Despite this, MAPK signalling cascade is less characterized in crop legumes. To fill this void, we present here a comprehensive phylogeny of MAPK kinases (MKKs) and MAPKs identified from 16 l...

journal_title：Scientific reports

authors： Purayannur S,Kumar K,Kaladhar VC,Verma PK

更新日期：2017-07-10 00:00:00

abstract：:Gyroviruses (GyVs) are small, single-stranded, circular DNA viruses in the genus Gyrovirus, which consists of the chicken anemia virus (CAV) prototype and nine other viral species. These different GyV species have been reported in chickens, humans, mice, and companion animals. To date, CAV has been identified in the f...

journal_title：Scientific reports

authors： Niu JT,Yi SS,Dong GY,Guo YB,Zhao YL,Huang HL,Wang K,Hu GX,Dong H

更新日期：2019-09-16 00:00:00

abstract：:Early antiretroviral therapy (ART) initiation is a recommended public health approach for the prevention of HIV-1 transmission. In this cohort study, we included 13132 serodiscordant couples. ART was initiated for patients with CD4+ T cell counts less than 200 cells/uL, 350 cells/uL, and 500 cells/uL respectively. Thi...

journal_title：Scientific reports

authors： Liu P,Tang Z,Lan G,Zhu Q,Chen H,You Y,Yang X,Liang S,Chen Y,Xing H,Liao L,Feng Y,Shen Z,Ruan Y,Shao Y

更新日期：2018-02-21 00:00:00

abstract：:Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in the salvage pathway of nicotinamide adenine dinucleotide biosynthesis. NAMPT protein is a secreted plasma biomarker in inflammation and in cancer. The NAMPT enzymatic inhibitor, FK866, acts as an inducer of apoptosis and is a cancer therapeuti...

journal_title：Scientific reports

authors： Zhou T,Wang T,Garcia JG

更新日期：2014-08-22 00:00:00

abstract：:Mutations in the SNX14 gene cause spinocerebellar ataxia, autosomal recessive 20 (SCAR20) in both humans and dogs. Studies implicating the phenotypic consequences of SNX14 mutations to be consequences of subcellular disruption to autophagy and lipid metabolism have been limited to in vitro investigation of patient-der...

journal_title：Scientific reports

authors： Bryant D,Seda M,Peskett E,Maurer C,Pomeranz G,Ghosh M,Hawkins TA,Cleak J,Datta S,Hariri H,Eckert KM,Jafree DJ,Walsh C,Demetriou C,Ishida M,Alemán-Charlet C,Vestito L,Seselgyte R,McDonald JG,Bitner-Glindzicz M,Hemb

更新日期：2020-08-13 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

journal_title：Scientific reports

authors： Krukowski K,Feng X,Paladini MS,Chou A,Sacramento K,Grue K,Riparip LK,Jones T,Campbell-Beachler M,Nelson G,Rosi S

更新日期：2018-07-03 00:00:00

abstract：:Southern hemisphere humpback whales are classified as high-fidelity Antarctic krill consumers and as such are vulnerable to variability and long-term changes in krill biomass. Evidence of heterogeneous feeding patterns of east coast of Australia migrating humpback whales has been observed, warranting a comprehensive a...

journal_title：Scientific reports

authors： Groß J,Virtue P,Nichols PD,Eisenmann P,Waugh CA,Bengtson Nash S

更新日期：2020-10-26 00:00:00

abstract：:Electrically pumped GaAsBi/GaAs quantum well lasers are a promising new class of near-infrared devices where, by use of the unusual band structure properties of GaAsBi alloys, it is possible to suppress the dominant energy-consuming Auger recombination and inter-valence band absorption loss mechanisms, which greatly i...

journal_title：Scientific reports

authors： Marko IP,Broderick CA,Jin S,Ludewig P,Stolz W,Volz K,Rorison JM,O'Reilly EP,Sweeney SJ

更新日期：2016-07-01 00:00:00

abstract：:The relationship between biodiversity and ecological functioning is a central issue in freshwater ecology, but how this relationship is influenced by hydrological connectivity stress is still unknown. In this study we analyzed the dynamic of the phytoplankton alpha diversity indices and their relationships with trophi...

journal_title：Scientific reports

authors： Meng F,Li Z,Li L,Lu F,Liu Y,Lu X,Fan Y

更新日期：2020-12-07 00:00:00

abstract：:The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Fl...

journal_title：Scientific reports

authors： Kuhn BM,Nodzyński T,Errafi S,Bucher R,Gupta S,Aryal B,Dobrev P,Bigler L,Geisler M,Zažímalová E,Friml J,Ringli C

更新日期：2017-02-06 00:00:00

abstract：:The sequential paradigm of data acquisition and analysis in next-generation sequencing leads to high turnaround times for the generation of interpretable results. We combined a novel real-time read mapping algorithm with fast variant calling to obtain reliable variant calls still during the sequencing process. Thereby...

journal_title：Scientific reports

authors： Loka TP,Tausch SH,Renard BY

更新日期：2019-11-11 00:00:00

abstract：:Altered neural mechanisms are well-acknowledged in irritable bowel syndrome (IBS), a disorder of brain-gut-communication highly comorbid with anxiety and depression. As a key hub in corticolimbic inhibition, medial prefrontal cortex (mPFC) may be involved in disturbed emotion regulation in IBS. However, aberrant mPFC ...

journal_title：Scientific reports

authors： Icenhour A,Tapper S,Bednarska O,Witt ST,Tisell A,Lundberg P,Elsenbruch S,Walter S

更新日期：2019-09-19 00:00:00

abstract：:A novel strategy for amplification full-length cDNA and promoter sequences has been developed using bioinformatics technology and multiplexed PCR methods in this study. The amplification of 3' ends of cDNA is performed according to the modified classic 3' RACE techniques, therein the more efficient and effective oligo...

journal_title：Scientific reports

authors： Chen N,Wang WM,Wang HL

更新日期：2016-01-13 00:00:00

abstract：:Metabolic syndrome (MS) could be associated with liver function. Our study aimed to investigate the association between liver function and MS in a large cohort of Chinese men and women. We enrolled 32,768 ostensibly healthy participants. The associations between liver function and MS of both genders were analyzed sepa...

journal_title：Scientific reports

authors： Wang S,Zhang J,Zhu L,Song L,Meng Z,Jia Q,Li X,Liu N,Hu T,Zhou P,Zhang Q,Liu L,Song K,Jia Q

更新日期：2017-03-20 00:00:00

abstract：:A major translational challenge in the fields of therapeutic angiogenesis and regenerative medicine is the need to create functional microvasculature. The purpose of this study was to assess whether a potentially autologous endothelial cell (EC) source derived from human induced pluripotent stem cells (iPSC-ECs) can f...

journal_title：Scientific reports

authors： Bezenah JR,Kong YP,Putnam AJ

更新日期：2018-02-08 00:00:00

abstract：:Traffic-related air pollution is known to be associated with skin aging manifestations. We previously found that the use of fossil fuels was associated with skin aging, but no direct link between indoor air pollutants and skin aging manifestations has ever been shown. Here we directly measured the indoor PM2.5 exposur...

journal_title：Scientific reports

authors： Ding A,Yang Y,Zhao Z,Hüls A,Vierkötter A,Yuan Z,Cai J,Zhang J,Gao W,Li J,Zhang M,Matsui M,Krutmann J,Kan H,Schikowski T,Jin L,Wang S

更新日期：2017-11-10 00:00:00

abstract：:Anaerobic digestion is a common technology to biologically stabilize wasted solids produced in municipal wastewater treatment. Its efficiency is usually evaluated by calculating the reduction in volatile solids, which assumes no biomass growth associated with digestion. To determine whether this assumption is valid an...

journal_title：Scientific reports

authors： Mei R,Narihiro T,Nobu MK,Kuroda K,Liu WT

更新日期：2016-09-26 00:00:00

abstract：:Triggering receptor expressed on myeloid cells-1(TREM-1) is a member of the superimmunoglobulin receptor family. We have previously shown that TREM-1 prolongs survival of macrophages treated with lipoolysaccharide through Egr2-Bcl2 signaling. Recent studies suggest a role for TREM-1 in viral immunity. Human immunodefi...

journal_title：Scientific reports

authors： Yuan Z,Fan X,Staitieh B,Bedi C,Spearman P,Guidot DM,Sadikot RT

更新日期：2017-02-09 00:00:00

abstract：:3'-Sialyllactose (3'-SL), a natural prebiotic, maintains immune homeostasis and exerts anti-inflammatory and anti-arthritic effects. Although regulatory T cells (Tregs) prevent excessive inflammation and maintain immune tolerance, the effect of 3'-SL on Treg regulation is unclear. This study aimed to investigate the e...

journal_title：Scientific reports

authors： Kang LJ,Oh E,Cho C,Kwon H,Lee CG,Jeon J,Lee H,Choi S,Han SJ,Nam J,Song CU,Jung H,Kim HY,Park EJ,Choi EJ,Kim J,Eyun SI,Yang S

更新日期：2020-03-27 00:00:00

abstract：:Here we present spatio-temporal localization of Kremen1, a transmembrane receptor, in the mammalian cochlea, and investigate its role in the formation of sensory organs in mammal and fish model organisms. We show that Kremen1 is expressed in prosensory cells during cochlear development and in supporting cells of the a...

journal_title：Scientific reports

authors： Mulvaney JF,Thompkins C,Noda T,Nishimura K,Sun WW,Lin SY,Coffin A,Dabdoub A

更新日期：2016-08-23 00:00:00

abstract：:As a follow-up on the data presented for seals, we herein report and discuss outcomes resulting from a retrospective evaluation of harbour porpoise stranding and necropsy data from Schleswig-Holstein, Germany (n = 4463) to enable an objective evaluation of potential ecological effects of grey seal predation on porpois...

journal_title：Scientific reports

authors： van Neer A,Gross S,Kesselring T,Grilo ML,Ludes-Wehrmeister E,Roncon G,Siebert U

更新日期：2020-10-01 00:00:00

abstract：:Broadband acoustic absorbers with thin thickness are highly desired in practical situations such as architectural acoustics, yet it is still challenging to achieve high absorption by using structure with limited thickness. Here we report the theoretical optimal design, numerical simulation and experimental demonstrati...

journal_title：Scientific reports

authors： Gao YX,Lin YP,Zhu YF,Liang B,Yang J,Yang J,Cheng JC

更新日期：2020-07-01 00:00:00

abstract：:Age of complementary foods introduction is associated with childhood anemia, but the ideal age for the introduction of complementary foods to infants is a continuing topic of debate. We examined the longitudinal association between complementary foods introduction age and risk of anemia in 18,446 children from the Jia...

journal_title：Scientific reports

authors： Wang F,Liu H,Wan Y,Li J,Chen Y,Zheng J,Huang T,Li D

更新日期：2017-03-23 00:00:00

abstract：:Some neural network can be trained by transfer learning, which uses a pre-trained neural network as the source task, for a small target task's dataset. The performance of the transfer learning depends on the knowledge (i.e., layers) selected from the pre-trained network. At present, this knowledge is usually chosen by...

journal_title：Scientific reports

authors： Imai S,Kawai S,Nobuhara H

更新日期：2020-05-18 00:00:00

abstract：:Prior ex vivo histological postmortem studies of autism spectrum disorder (ASD) have shown gray matter microstructural abnormalities, however, in vivo examination of gray matter microstructure in ASD has remained scarce due to the relative lack of non-invasive methods to assess it. The aim of this work was to evaluate...

journal_title：Scientific reports

authors： McKenna F,Miles L,Donaldson J,Castellanos FX,Lazar M

更新日期：2020-12-08 00:00:00

abstract：:Soil water retention curve (SWRC) plays an important role in simulating soil water movement and assessing soil water holding capacity and availability. Comparison of fitness between different models to determine the best SWRC model of specific regions is required. In this study, three popular models, van Genuchten, Br...

journal_title：Scientific reports

authors： Pan T,Hou S,Liu Y,Tan Q

更新日期：2019-12-05 00:00:00