HIV-related proteins prolong macrophage survival through induction of Triggering receptor expressed on myeloid cells-1.

abstract：:Oxidovanadium complexes with organic ligands are well known to have cytotoxic or differentiating capabilities against a range of cancer cell types. Their limited use in clinical testing though has resulted largely from uncertainties about the long-term toxicities of such complexes, due in part to the speciation to van...

journal_title：Scientific reports

authors： Irving E,Tagalakis AD,Maeshima R,Hart SL,Eaton S,Lehtonen A,Stoker AW

更新日期：2020-10-07 00:00:00

abstract：:The restoration of dentine lost in deep caries lesions in teeth is a routine and common treatment that involves the use of inorganic cements based on calcium or silicon-based mineral aggregates. Such cements remain in the tooth and fail to degrade and thus normal mineral volume is never completely restored. Here we de...

journal_title：Scientific reports

authors： Neves VC,Babb R,Chandrasekaran D,Sharpe PT

更新日期：2017-01-09 00:00:00

abstract：:Green reduction of graphene oxide (GO) by phytochemicals was explored using the aqueous extract of kaffir lime peels. The research methods included preparation of extracts, preparation of GO, preparation and characterization of reduced-GO (RGO) using Fourier Transform Infrared (FTIR), X-ray diffraction (XRD), and UV-V...

journal_title：Scientific reports

authors： Wijaya R,Andersan G,Permatasari Santoso S,Irawaty W

更新日期：2020-01-20 00:00:00

abstract：:Jute fibre is the second most important fibre next to cotton. It is obtained from the bark of plant through microbial retting process. Here we report optimized microbial retting protocol that can lower retting period and produce high fibre quality. A total of 451 bacterial colonies have been isolated from five jute re...

journal_title：Scientific reports

authors： Hasan R,Aktar N,Kabir SMT,Honi U,Halim A,Islam R,Sarker MDH,Haque MS,Alam MM,Islam MS

更新日期：2020-03-20 00:00:00

abstract：:Atmospheric new particle formation (NPF) and growth significantly influences climate by supplying new seeds for cloud condensation and brightness. Currently, there is a lack of understanding of whether and how marine biota emissions affect aerosol-cloud-climate interactions in the Arctic. Here, the aerosol population ...

journal_title：Scientific reports

authors： Dall Osto M,Beddows DCS,Tunved P,Krejci R,Ström J,Hansson HC,Yoon YJ,Park KT,Becagli S,Udisti R,Onasch T,O Dowd CD,Simó R,Harrison RM

更新日期：2017-06-12 00:00:00

abstract：:A binary metallic superoscillatory lens assisted with annular subwavelength slits is proposed, which generates a longitudinally-polarized super-resolution focal point. The annular slits are designed to selectively transmit radially-polarized light. Simulations using the finite element method show a 0.24 λ focal spot w...

journal_title：Scientific reports

authors： Kim H,Rogers ETF

更新日期：2020-01-28 00:00:00

abstract：:Gallid alphaherpesvirus 2 (GaHV2) is an oncogenic avian herpesvirus inducing Marek's disease (MD) and rapid-onset T-cell lymphomas. To reveal molecular events in MD pathogenesis and tumorigenesis, the dynamic splenic transcriptome of GaHV2-infected chickens during early infection and pathogenic phases has been determi...

journal_title：Scientific reports

authors： Dang L,Teng M,Li HW,Li HZ,Ma SM,Zhao P,Li XJ,Deng RG,Zhang GP,Luo J

更新日期：2017-09-14 00:00:00

abstract：:Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti-ASD drug. Many reports have described the efficacy of intranasal OXT therapy to improve the core symptoms of patients with ASD; however, the un...

journal_title：Scientific reports

authors： Horiai M,Otsuka A,Hidema S,Hiraoka Y,Hayashi R,Miyazaki S,Furuse T,Mizukami H,Teruyama R,Tamura M,Bito H,Maejima Y,Shimomura K,Nishimori K

更新日期：2020-12-17 00:00:00

abstract：:A novel marine strain representing efficient degradation ability toward brown algae was isolated, identified, and assigned to Bacillus weihaiensis Alg07. The alga-associated marine bacteria promote the nutrient cycle and perform important functions in the marine ecosystem. The de novo sequencing of the B. weihaiensis ...

journal_title：Scientific reports

authors： Zhu Y,Chen P,Bao Y,Men Y,Zeng Y,Yang J,Sun J,Sun Y

更新日期：2016-11-30 00:00:00

abstract：:Increasing evidence suggest that the glucose-lowering drug metformin exerts a valuable anti-senescence role. The ability of metformin to affect the biogenesis of selected microRNAs (miRNAs) was recently suggested. MicroRNA isoforms (isomiRs) are distinct variations of miRNA sequences, harboring addition or deletion of...

journal_title：Scientific reports

authors： Giuliani A,Londin E,Ferracin M,Mensà E,Prattichizzo F,Ramini D,Marcheselli F,Recchioni R,Rippo MR,Bonafè M,Rigoutsos I,Olivieri F,Sabbatinelli J

更新日期：2020-12-11 00:00:00

abstract：:Quorum-sensing (QS) systems exist universally in bacteria to regulate multiple biological functions. Klebsiella pneumoniae, an industrially important bacterium that produces bio-based chemicals such as 2,3-butanediol and acetoin, can secrete a furanosyl borate diester (AI-2) as the signalling molecule mediating a QS s...

journal_title：Scientific reports

authors： Sun S,Zhang H,Lu S,Lai C,Liu H,Zhu H

更新日期：2016-12-07 00:00:00

abstract：:Energy storage devices that provide high specific power without compromising on specific energy are highly desirable for many electric-powered applications. Here, we demonstrate that polymer organic radical gel materials support fast bulk-redox charge storage, commensurate to surface double layer ion exchange at carbo...

journal_title：Scientific reports

authors： Vlad A,Singh N,Melinte S,Gohy JF,Ajayan PM

更新日期：2016-02-26 00:00:00

abstract：:Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap. Here, we evaluated the impact of sexual dimorphism and of the estrous cycle on muscle strength and running power of C57BL/6 mice. Like men, male mi...

journal_title：Scientific reports

authors： Aguiar AS Jr,Speck AE,Amaral IM,Canas PM,Cunha RA

更新日期：2018-07-16 00:00:00

abstract：:The role of changes in dopamine neuronal activity during the development of symptoms in affective disorders remains controversial. Here, we show that inactivation of NMDA receptors on dopaminergic neurons in adult mice led to the development of affective disorder-like symptoms. The loss of NMDA receptors altered activ...

journal_title：Scientific reports

authors： Jastrzębska K,Walczak M,Cieślak PE,Szumiec Ł,Turbasa M,Engblom D,Błasiak T,Parkitna JR

更新日期：2016-11-17 00:00:00

abstract：:Thin waveguides such as graded-index lenses and fiber bundles are often used as imaging probes for high-resolution endomicroscopes. However, strong back-reflection from the end surfaces of the probes makes it difficult for them to resolve weak contrast objects, especially in the reflectance-mode imaging. Here we propo...

journal_title：Scientific reports

authors： Yoon C,Kang M,Hong JH,Yang TD,Xing J,Yoo H,Choi Y,Choi W

更新日期：2017-07-26 00:00:00

abstract：:Models of biological processes are often subject to different sources of noise. Developing an understanding of the combined effects of different types of uncertainty is an open challenge. In this paper, we study a variant of the susceptible-infective-recovered model of epidemic spread, which combines both agent-to-age...

journal_title：Scientific reports

authors： Herrerías-Azcué F,Galla T

更新日期：2017-10-11 00:00:00

abstract：:Previous studies have investigated the use of mesenchymal stem cells (MSCs) to treat damaged kidneys. However, the effect of adipose-derived MSCs (ASCs) on vascular calcification in chronic kidney disease (CKD) is still poorly understood. In the present study, we explored the potential of ASCs for the treatment of CKD...

journal_title：Scientific reports

authors： Yokote S,Katsuoka Y,Yamada A,Ohkido I,Yokoo T

更新日期：2017-10-25 00:00:00

abstract：:Globally, there has been an increase in the use of herbal remedies including traditional Chinese medicine (TCM). There is a perception that products are natural, safe and effectively regulated, however, regulatory agencies are hampered by a lack of a toolkit to audit ingredient lists, adulterants and constituent activ...

journal_title：Scientific reports

authors： Coghlan ML,Maker G,Crighton E,Haile J,Murray DC,White NE,Byard RW,Bellgard MI,Mullaney I,Trengove R,Allcock RJ,Nash C,Hoban C,Jarrett K,Edwards R,Musgrave IF,Bunce M

更新日期：2015-12-10 00:00:00

abstract：:Many chemical reactions in biological cells occur at very low concentrations of constituent molecules. Thus, transcriptional gene-regulation is often controlled by poorly expressed transcription-factors, such as E.coli lac repressor with few tens of copies. Here we study the effects of inherent concentration fluctuati...

journal_title：Scientific reports

authors： Pulkkinen O,Metzler R

更新日期：2015-12-04 00:00:00

abstract：:Tumor-associated immune response plays a critical role in cancer pathogenesis. This study evaluated clinical implications of T cell cytokines and regulatory T cells (Tregs) in HCC patients treated with TACE. Whole blood was obtained for analysis of T cell cytokines (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-12p70...

journal_title：Scientific reports

authors： Lee HL,Jang JW,Lee SW,Yoo SH,Kwon JH,Nam SW,Bae SH,Choi JY,Han NI,Yoon SK

更新日期：2019-03-01 00:00:00

abstract：:CRISPR/Cas9 is a valuable tool for both basic and applied research that has been widely applied to different plant species. Nonetheless, a systematical assessment of the efficiency of this method is not available for the allotetraploid Brassica napus-an important oilseed crop. In this study, we examined the mutation e...

journal_title：Scientific reports

authors： Yang H,Wu JJ,Tang T,Liu KD,Dai C

更新日期：2017-08-08 00:00:00

abstract：:The major virulence factors of Clostridium difficile are toxins A and B. These toxins are encoded by tcdA and tcdB genes, which form a pathogenicity locus (PaLoc) together with three additional genes that have been implicated in regulation (tcdR and tcdC) and secretion (tcdE). To date, the PaLoc has always been found ...

journal_title：Scientific reports

authors： Monot M,Eckert C,Lemire A,Hamiot A,Dubois T,Tessier C,Dumoulard B,Hamel B,Petit A,Lalande V,Ma L,Bouchier C,Barbut F,Dupuy B

更新日期：2015-10-08 00:00:00

abstract：:Biochar (BC) and magnetite (Fe3O4) nanoparticles (MNP) have both received considerable recent attention in part due to their potential use in water treatment. While both are effective independently in the removal of a range of anionic metals from aqueous solution, the efficacy of these materials is reduced considerabl...

journal_title：Scientific reports

authors： Alam MS,Bishop B,Chen N,Safari S,Warter V,Byrne JM,Warchola T,Kappler A,Konhauser KO,Alessi DS

更新日期：2020-11-04 00:00:00

abstract：:Attention can be allocated to mental representations to select information from working memory. To date, it remains ambiguous whether such retroactive shifts of attention involve the inhibition of irrelevant information or the prioritization of relevant information. Investigating asymmetries in posterior alpha-band os...

journal_title：Scientific reports

authors： Klatt LI,Getzmann S,Begau A,Schneider D

更新日期：2020-08-17 00:00:00

abstract：:The Yiyuan hominin fossil site is one of the few localities in China where a partial skullcap and several loose teeth of Homo erectus have been discovered. Yiyuan was previously assigned broadly to the Middle Pleistocene by biostratigraphical correlation and ESR/U-series dating. Here, we report the first application o...

journal_title：Scientific reports

authors： Guo Y,Sun C,Luo L,Yang L,Han F,Tu H,Lai Z,Jiang H,Bae CJ,Shen G,Granger D

更新日期：2019-05-06 00:00:00

abstract：:Secondary visual loss occurs in millions of patients due to a wound-healing response, known as posterior capsule opacification (PCO), following cataract surgery. An intraocular lens (IOL) is implanted into residual lens tissue, known as the capsular bag, following cataract removal. Standard IOLs allow the anterior and...

journal_title：Scientific reports

authors： Eldred JA,McDonald M,Wilkes HS,Spalton DJ,Wormstone IM

更新日期：2016-04-14 00:00:00

abstract：:Activation of the inflammasome is involved in the progression of retinal degenerative diseases, in particular, in the pathogenesis of Age-Related Macular Degeneration (AMD), with NLRP3 activation the focus of many investigations. In this study, we used genetic and pharmacological approaches to explore the role of the ...

journal_title：Scientific reports

authors： Wooff Y,Fernando N,Wong JHC,Dietrich C,Aggio-Bruce R,Chu-Tan JA,Robertson AAB,Doyle SL,Man SM,Natoli R

更新日期：2020-02-10 00:00:00

abstract：:The natural ligand 17β-estradiol (E2) is so far believed to induce a unique agonist-bound active conformation in the ligand binding domain (LBD) of the estrogen receptors (ERs). Both subtypes, ERα and ERβ, are transcriptionally activated in the presence of E2 with ERβ being somewhat less active than ERα under similar ...

journal_title：Scientific reports

authors： Souza PCT,Textor LC,Melo DC,Nascimento AS,Skaf MS,Polikarpov I

更新日期：2017-06-14 00:00:00

abstract：:The natural peptide chensinin-1 doesnot exhibit its desired biological properties. In this study, the mutant MC1-1 was designed by replacing Gly in the chensinin-1 sequence with Trp. Mutants MC1-2 and MC1-3 were designed based on the MC1-1 sequence to investigate the specific role of His residues. The mutated peptides...

journal_title：Scientific reports

authors： Dong W,Mao X,Guan Y,Kang Y,Shang D

更新日期：2017-01-05 00:00:00

abstract：:The manuscript highlights the efficacy of silver ions to act as a unique probe for the detection of bacterial contamination in water samples. The bacterial cell membrane adherence property of the silver ions was employed to develop two different bacterial detection assays employing colorimetric and electrochemical tec...

journal_title：Scientific reports

authors： Kumar V,Chopra A,Bisht B,Bhalla V

更新日期：2020-07-20 00:00:00