Abstract:
:Traffic-related air pollution is known to be associated with skin aging manifestations. We previously found that the use of fossil fuels was associated with skin aging, but no direct link between indoor air pollutants and skin aging manifestations has ever been shown. Here we directly measured the indoor PM2.5 exposure in 30 households in Taizhou, China. Based on the directly measured PM2.5 exposure and questionnaire data of indoor pollution sources, we built a regression model to predict the PM2.5 exposure in larger datasets including an initial examination group (N = 874) and a second examination group (N = 1003). We then estimated the association between the PM2.5 exposure and skin aging manifestations by linear regression. In the initial examination group, we showed that the indoor PM2.5 exposure levels were positively associated with skin aging manifestation, including score of pigment spots on forehead (12.5% more spots per increase of IQR, P-value 0.0371), and wrinkle on upper lip (7.7% more wrinkle on upper lip per increase of IQR, P-value 0.0218). The results were replicated in the second examination group as well as in the pooled dataset. Our study provided evidence that the indoor PM2.5 exposure is associated with skin aging manifestation in a Chinese population.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Ding A,Yang Y,Zhao Z,Hüls A,Vierkötter A,Yuan Z,Cai J,Zhang J,Gao W,Li J,Zhang M,Matsui M,Krutmann J,Kan H,Schikowski T,Jin L,Wang Sdoi
10.1038/s41598-017-15295-8subject
Has Abstractpub_date
2017-11-10 00:00:00pages
15329issue
1issn
2045-2322pii
10.1038/s41598-017-15295-8journal_volume
7pub_type
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