Abstract:
:Microalgal harvesting and dewatering are the main bottlenecks that need to be overcome to tap the potential of microalgae for production of valuable compounds. Water surface-floating microalgae form robust biofilms, float on the water surface along with gas bubbles entrapped under the biofilms, and have great potential to overcome these bottlenecks. However, little is known about the molecular mechanisms involved in the water surface-floating phenotype. In the present study, we analysed the genome sequence of a water surface-floating microalga Chlorococcum sp. FFG039, with a next generation sequencing technique to elucidate the underlying mechanisms. Comparative genomics study with Chlorococcum sp. FFG039 and other non-floating green microalgae revealed some of the unique gene families belonging to this floating microalga, which may be involved in biofilm formation. Furthermore, genetic transformation of this microalga was achieved with an electroporation method. The genome information and transformation techniques presented in this study will be useful to obtain molecular insights into the water surface-floating phenotype of Chlorococcum sp. FFG039.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Maeda Y,Nojima D,Sakurai M,Nomaguchi T,Ichikawa M,Ishizuka Y,Tanaka Tdoi
10.1038/s41598-019-47612-8subject
Has Abstractpub_date
2019-08-01 00:00:00pages
11200issue
1issn
2045-2322pii
10.1038/s41598-019-47612-8journal_volume
9pub_type
杂志文章abstract::The prognosis of malignancies has improved in recent years, subsequent primary cancers (SPCs) have become more frequent. This study investigates the patterns of lung cancer involved multiple primary cancers. We enrolled 206,619 primary lung cancer patients and 2,071,922 patients with other primary malignancies from Su...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-06763-2
更新日期:2017-07-25 00:00:00
abstract::We investigate temperature smearing effects on the electron-boson spectral density function (I(2)χ(ω)) obtained from optical data using a maximum entropy inversion method. We start with two simple model input I(2)χ(ω), calculate the optical scattering rates at selected temperatures using the model input spectral densi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep23647
更新日期:2016-03-31 00:00:00
abstract::Obstructive sleep apnea (OSA) is associated with increasing risk of recurrent stroke and mortality. Nasogastric tubes used by dysphagic stroke patients may interfere with nasal continuous positive airway pressure (CPAP) due to air leakage. This study was evaluated the effects and short-term tolerability of high-flow n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-65335-z
更新日期:2020-05-22 00:00:00
abstract::The manifestation of cognitive and physical impairment in stroke patients before the acute event suggests accumulating subclinical vascular pathology in the brain. We investigated whether impairments in cognitive and physical functioning were associated with an increased stroke risk. Between 2002 and 2008, 8,519 strok...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-63295-y
更新日期:2020-04-14 00:00:00
abstract::Soils - constituting the largest terrestrial carbon pool - are vulnerable to climatic warming. Currently existing uncertainties regarding carbon fluxes within terrestrial systems can be addressed by studies of past carbon cycle dynamics and related climate change recorded in sedimentary successions. Here we show an ex...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31930
更新日期:2016-08-24 00:00:00
abstract::Neurofeedback-guided motor imagery training (NF-MIT) has been suggested as a promising therapy for stroke-induced motor impairment. Whereas much NF-MIT research has aimed at signal processing optimization, the type of sensory feedback given to the participant has received less attention. Often the feedback signal is h...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37696
更新日期:2016-11-21 00:00:00
abstract::This study aimed to develop a cationic nanosuspension of chitosan (CS) and methoxy poly(ethylene glycol)-poly(ε-caprolactone) (MPEG-PCL) for ocular delivery of diclofenac (DIC). MPEG-PCL-CS block polymer was synthesized by covalent coupling of MPEG-PCL with CS. The critical micelle concentration of the MPEG-PCL-CS blo...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep11337
更新日期:2015-06-12 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-30955-z
更新日期:2018-08-20 00:00:00
abstract::SOX7 as a tumor suppressor belongs to the SOX F gene subfamily and is associated with a variety of human cancers, including breast cancer, but the mechanisms involved are largely unclear. In the current study, we investigated the interactions between SOX7 and AXIN2 in their co-regulation on the Wnt/β-catenin signal pa...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep26136
更新日期:2016-05-18 00:00:00
abstract::RNA-binding proteins are key regulators of post-transcriptional processes such as alternative splicing and mRNA stabilization. Rbm24 acts as a regulator of alternative splicing in heart and skeletal muscle, and is essential for sarcomere assembly. Homozygous inactivation of Rbm24 in mice disrupts cardiac development a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-64667-0
更新日期:2020-05-06 00:00:00
abstract::Conventional crystalline β-MnO2 usually exhibits poor electrochemical activities due to the narrow tunnels in its rutile-type structure. In this study, we synthesized a novel 2D β-MnO2 network with long-range order assembled by β-MnO2 nanowires and demonstrated that the novel 2D β-MnO2 network exhibits enhanced electr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02193
更新日期:2013-01-01 00:00:00
abstract::Based on the electrical characteristic detection technology, the quantitative prediction models of sensory score and physical and chemical quality Index (theaflavins, thearubigins, and theabrownins) were established by using the fermented products of Congou black tea as the research object. The variation law of electr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-58637-9
更新日期:2020-01-31 00:00:00
abstract::Intestinal microbiome changes that occur in HIV positive individuals on different antiretroviral therapy (ART) regimens are important to understand, as they are potentially linked with chronic inflammation and microbiome-linked comorbidities that occur at increased incidence in this population. We conducted a cross-se...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43741
更新日期:2017-03-06 00:00:00
abstract::Microvascular endothelial cell heterogeneity and its relationship to hemodynamics remains poorly understood due to a lack of sufficient methods to examine these parameters in vivo at high resolution throughout an angiogenic network. The availability of surrogate markers for functional vascular proteins, such as green ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-08982-z
更新日期:2017-08-22 00:00:00
abstract::Asymmetric cell divisions are required for cellular diversity and defects can lead to altered daughter cell fates and numbers. In a genetic screen for C. elegans mutants with defects in dopaminergic head neuron specification or differentiation, we isolated a new allele of the transcription factor HAM-1 [HSN (Hermaphro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04375-4
更新日期:2017-06-28 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-020-63162-w
更新日期:2020-04-15 00:00:00
abstract::This work aimed to prepare solvent-free or green Bi2O2CO3 for quantum dot nanostructures (QDNSs) based on cellulose as a stabilizer and green capping agent to sorafenib delivery for liver targeting. Because the walnut tree is one of the most abundant trees in Iran, it was tried to synthesize Bi2O2CO3 QDNSs using a wal...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-78266-6
更新日期:2020-12-04 00:00:00
abstract::Bast fibres are long extraxylary cells which mechanically support the phloem and they are divided into xylan- and gelatinous-type, depending on the composition of their secondary cell walls. The former, typical of jute/kenaf bast fibres, are characterized by the presence of xylan and a high degree of lignification, wh...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-05200-8
更新日期:2017-07-10 00:00:00
abstract::Chinese sturgeon (Acipenser sinensis) has been listed as a critically endangered species on the IUCN Red List and is an endemic fish of China. Five sets of duplex polymerase chain reactions (PCR) assays were developed with 10 tetranucleotide microsatellites for Chinese sturgeon. The size of CS57, ZHX43, ZHX69, AS105, ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-60401-y
更新日期:2020-02-26 00:00:00
abstract::Angiogenin (hANG), a member of the Ribonuclease A superfamily has angiogenic, neurotrophic and neuroprotective activities. Mutations in hANG have been found in patients with Amyotrophic lateral sclerosis (ALS). The zebrafish (Danio rerio) rnasel-1, 2 and 3 are orthologues of hANG and of these only Rnasel-1 and Rnasel-...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-37140-2
更新日期:2019-02-01 00:00:00
abstract::Physical activity (PA) is known to influence cognitive function. However, the impact of PA on patients with cerebrovascular disease (CVD) has not yet been elucidated. PA and cognitive function have not been measured simultaneously over time, which makes it difficult to evaluate their relationship. The purpose of this ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-40460-6
更新日期:2019-03-07 00:00:00
abstract::Small bowel capsule endoscopy (SBCE) and balloon-assisted endoscopy (BAE) have revolutionized the diagnosis and treatment of small bowel bleeding (SBB), allowing access to the small bowel and identification of specific bleeding lesions. However, some patients experience rebleeding after small bowel investigation, and ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24868-0
更新日期:2018-04-23 00:00:00
abstract::This corrects the article DOI: 10.1038/srep25577. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/srep46944
更新日期:2018-02-16 00:00:00
abstract::Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that oestrogen receptors (ERs) play a major role in postmenopausal obesity and depression. However, little is known regarding the ER subtype-specific effects on obesity...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-04946-5
更新日期:2017-07-05 00:00:00
abstract::Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are desirable for diabetes, especially in patients with overweight/obesity. We aimed to determine whether GLP-1RAs exhibit different glucose-lowering efficacies between Asian type 2 diabetes (T2D) patients with and without overweight/obesity. Randomized controlled t...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-017-16018-9
更新日期:2017-11-22 00:00:00
abstract::Optogenetics allows precise, fast and reversible intervention in biological processes. Light-sheet microscopy allows observation of the full course of Drosophila embryonic development from egg to larva. Bringing the two approaches together allows unparalleled precision into the temporal regulation of signaling pathway...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-16879-0
更新日期:2017-11-30 00:00:00
abstract::NiFe nanoparticles-decorated & N-doped graphene is introduced as an effective and stable non-precious electrocatalyst for ORR in the acid medium. Compared to conventional Pt/C electrodes under the same conditions, the proposed nanocatalyst shows closer onset potential and current density. Typically, the observed onset...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22114-1
更新日期:2018-02-28 00:00:00
abstract::Increasing attention is given to personalized tumour therapy, where α-emitters can potentially play an important role. Alpha particles are ideal for localized cell killing because of their high linear energy transfer and short ranges. However, upon the emission of an α particle the daughter nuclide experiences a recoi...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-48298-8
更新日期:2019-08-12 00:00:00
abstract::Plant resistance can provide effective, economical, and sustainable pest control. Tolerance to the soybean aphid has been identified and confirmed in the soybean KS4202. Although its resistance mechanisms are not fully understood, evidence suggests that enhanced detoxification of reactive oxygen species (ROS) is an ac...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-33477-w
更新日期:2018-10-11 00:00:00
abstract::Pericytes regulate vessel stability and pericyte dysfunction contributes to retinopathies, stroke, and cancer. Here we define Notch as a key regulator of pericyte function during angiogenesis. In Notch1(+/-); Notch3(-/-) mice, combined deficiency of Notch1 and Notch3 altered pericyte interaction with the endothelium a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep16449
更新日期:2015-11-13 00:00:00