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Controlled and cellulose eco-friendly synthesis and characterization of Bi2O2CO3 quantum dot nanostructures (QDNSs) and drug delivery study.

Abstract：

:This work aimed to prepare solvent-free or green Bi2O2CO3 for quantum dot nanostructures (QDNSs) based on cellulose as a stabilizer and green capping agent to sorafenib delivery for liver targeting. Because the walnut tree is one of the most abundant trees in Iran, it was tried to synthesize Bi2O2CO3 QDNSs using a walnut skin extract. The saturation magnetization for Bi2O2CO3 QDNSs was calculated to be 68.1. Also, the size of products was measured at around 60-80 nm with the Debye-Scherrer equation. Moreover, the morphology, functional groups, and crystallography of the Bi2O2CO3 nanoparticles were investigated using atomic force microscopy, scanning electron microscopy, vibrating-sample magnetometer, and Uv-vis spectroscopy. The results demonstrated that Bi2O2CO3 QDNSs have opto-magnetic properties and they can be suggested as the candidate materials for the sorafenib delivery on the liver tissue. The optical band gap estimated for Bi2O2CO3 QDNSs was found to be red-shift from 3.22 eV. This study suggests the preparation of the Bi2O2CO3 QDNSs based on cellulose as new opto-magnetic materials at different temperatures of 180 °C, 200 °C, 220 °C, and 240 °C for sorafenib delivery as a type of biological therapy drug.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Samarehfekri H,Rahimi HR,Ranjbar M

doi

10.1038/s41598-020-78266-6

subject

Has Abstract

pub_date

2020-12-04 00:00:00

pages

21302

issue

1

issn

2045-2322

pii

10.1038/s41598-020-78266-6

journal_volume

10

pub_type

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