Convergence of multimodal sensory pathways to the mushroom body calyx in Drosophila melanogaster.

abstract：:Reverse-transcription quantitative real-time polymerase chain reaction (RT-qPCR) is widely used for mRNA quantification. To accurately measure changing gene transcript levels under different experimental conditions, the use of appropriate reference gene transcripts is instrumental. In T cell immunology, suitable refer...

journal_title：Scientific reports

authors： Geigges M,Gubser PM,Unterstab G,Lecoultre Y,Paro R,Hess C

更新日期：2020-06-10 00:00:00

abstract：:Biopharming for the production of recombinant pharmaceutical proteins in the mammary gland of transgenic animals is an attractive but laborious alternative compared to mammalian cell fermentation. The disadvantage of the lengthy process of genetically modifying an entire animal could be circumvented with somatic trans...

journal_title：Scientific reports

authors： Wagner S,Thresher R,Bland R,Laible G

更新日期：2015-10-14 00:00:00

abstract：:Psychopathic traits of conduct disorder (CD) have a core callous-unemotional (CU) component and an impulsive-antisocial component. Previous task-driven fMRI studies have suggested that psychopathic traits are associated with dysfunction of several brain areas involved in different cognitive functions (e.g., empathy, r...

journal_title：Scientific reports

authors： Pu W,Luo Q,Jiang Y,Gao Y,Ming Q,Yao S

更新日期：2017-09-12 00:00:00

abstract：:Methods that provide controlled influx of molecules into cells are of critical importance for uncovering cellular mechanisms, drug development and synthetic biology. However, reliable intracellular delivery without adversely affecting the cells is a major challenge. We developed a platform for on-demand intracellular ...

journal_title：Scientific reports

authors： Kavaldzhiev MN,Perez JE,Sougrat R,Bergam P,Ravasi T,Kosel J

更新日期：2018-07-02 00:00:00

abstract：:In a developing nervous system, endogenous electric field (EF) influence embryonic growth. We reported the EF-directed migration of both rat Schwann cells (SCs) and oligodendrocyte precursor cells (OPCs) and explored the molecular mechanism using RNA-sequencing assay. However, previous studies revealed the differentia...

journal_title：Scientific reports

authors： Yao L,Shippy T,Li Y

更新日期：2020-10-08 00:00:00

abstract：:Aerosol particles emitted from various human activities deteriorate air quality and are suggested to increase public health risk. Numerous studies have emphasized the relationship between the mass and/or number concentration of aerosols (or commonly known as particulate matter (PM)) in the atmosphere and the incidence...

journal_title：Scientific reports

authors： Ching J,Kajino M

更新日期：2018-06-11 00:00:00

abstract：:Prostate cancer (PCa) is the most common solid neoplasm diagnosed in developed countries. Nerve-sparing radical prostatectomy (NS-RP) has been widely accepted as the best choice treatment for localised PCa. However, erectile dysfunction (ED) and urinary incontinence are commonly observed after NS-RP. Using meta-analys...

journal_title：Scientific reports

authors： Li J,Shi Q,Pu C,Tang Y,Bai Y,Yuan H,Li X,Dong Q,Wei Q,Yuan J,Han P

更新日期：2014-07-23 00:00:00

abstract：:The Great Amazon Reef (GARS) is an extensive mesophotic reef ecosystem between Brazil and the Caribbean. Despite being considered as one of the most important mesophotic reef ecosystems of the South Atlantic, recent criticism on the existence of a living reef in the Amazon River mouth was raised by some scientists and...

journal_title：Scientific reports

authors： de Mahiques MM,Siegle E,Francini-Filho RB,Thompson FL,de Rezende CE,Gomes JD,Asp NE

更新日期：2019-09-23 00:00:00

abstract：:Strong hydrogen bonds such as F···H···F offer new strategies to fabricate molecular architectures exhibiting novel structures and properties. Along these lines and, to potentially realize hydrogen-bond mediated superexchange interactions in a frustrated material, we synthesized [H2F]2[Ni3F6(Fpy)12][SbF6]2 (Fpy = 3-flu...

journal_title：Scientific reports

authors： Manson JL,Brambleby J,Goddard PA,Spurgeon PM,Villa JA,Liu J,Ghannadzadeh S,Foronda F,Singleton J,Lancaster T,Clark SJ,Thomas IO,Xiao F,Williams RC,Pratt FL,Blundell SJ,Topping CV,Baines C,Campana C,Noll B

更新日期：2018-03-16 00:00:00

abstract：:Oxalate decarboxylase (OXDC) enzyme has immense biotechnological applications due to its ability to decompose anti-nutrient oxalic acid. Flammulina velutipes, an edible wood rotting fungus responds to oxalic acid by induction of OXDC to maintain steady levels of pH and oxalate anions outside the fungal hyphae. Here, w...

journal_title：Scientific reports

authors： Kamthan A,Kamthan M,Kumar A,Sharma P,Ansari S,Thakur SS,Chaudhuri A,Datta A

更新日期：2015-10-12 00:00:00

abstract：:During rescue operations related to the elimination of the effects of industrial accidents or natural disasters, extinguishing agents are used that affect the migration and transformation of contamination in the environment. Firefighting foam sprayed onto an oil spill slowly drains to an aqueous solution and penetrate...

journal_title：Scientific reports

authors： Rakowska J

更新日期：2020-06-01 00:00:00

abstract：:A patient's pain during mandibular third molar extraction often creates problems for a dental surgeon and can also cause immense patient discomfort, such as decreased quality of life, serious complications, or even danger to the patients' lives. Effective pain management is therefore of great importance. Conventional ...

journal_title：Scientific reports

authors： Yu F,Xiao Y,Liu H,Wu F,Lou F,Chen D,Bai M,Huang D,Wang C,Ye L

更新日期：2017-01-20 00:00:00

abstract：:Cellular clearance mechanisms including the autophagy-lysosome pathway are impaired in amyotrophic lateral sclerosis (ALS). One of the most important proteins involved in the regulation of autophagy is the lysosomal Ca2+ channel Mucolipin TRP channel 1 (TRPML1). Therefore, we investigated the role of TRPML1 in a neuro...

journal_title：Scientific reports

authors： Tedeschi V,Petrozziello T,Sisalli MJ,Boscia F,Canzoniero LMT,Secondo A

更新日期：2019-07-24 00:00:00

abstract：:New ionic liquids with multiple Brönsted acid sites were synthesized in ≥98% yield, and their inhibiting properties for the corrosion of carbon steel in 0.5 M HCl solution had been evaluated using electrochemical impedance spectroscopy, potentiodynamic polarization and weight loss method, finally the possible inhibiti...

journal_title：Scientific reports

authors： Cao S,Liu D,Zhang P,Yang L,Yang P,Lu H,Gui J

更新日期：2017-08-18 00:00:00

abstract：:The mechanism by which the Earth's magnetic field is generated is thought to be thermal convection in the metallic liquid iron core. Here we present results of a suite of self-consistent spherical shell computations with ultra-low viscosities that replicate this mechanism, but using diffusivities of momentum and magne...

journal_title：Scientific reports

authors： Sheyko A,Finlay C,Favre J,Jackson A

更新日期：2018-08-22 00:00:00

abstract：:Chronic venous disease (CVD) is a multifactorial condition representing one of the most common disorders among populations of Western countries. The heritability of about 17% suggests genetic risk factors in CVD etiology. However, so far the genetic causes are unknown. We undertook the hitherto first genome-wide assoc...

journal_title：Scientific reports

authors： Ellinghaus E,Ellinghaus D,Krusche P,Greiner A,Schreiber C,Nikolaus S,Gieger C,Strauch K,Lieb W,Rosenstiel P,Frings N,Fiebig A,Schreiber S,Franke A

更新日期：2017-04-04 00:00:00

abstract：:The two most common techniques for absolute protein quantification are based on either mass spectrometry (MS) or on immunochemical techniques, such as western blotting (WB). Western blotting is most often used for protein identification or relative quantification, but can also be deployed for absolute quantification i...

journal_title：Scientific reports

authors： Bennett RJ,Simpson DM,Holman SW,Ryan S,Brownridge P,Eyers CE,Colyer J,Beynon RJ

更新日期：2017-04-03 00:00:00

abstract：:The mechanism by which chronic metabolic acidosis (CMA) regulates sodium (Na(+))-chloride (Cl(-)) cotransporter (NCC) in the renal distal convoluted tubules remains unexplored. We examined the role of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and with-no-lysine kinase 4 (WNK4) on expression of NCC in mouse...

journal_title：Scientific reports

authors： Fang YW,Yang SS,Cheng CJ,Tseng MH,Hsu HM,Lin SH

更新日期：2016-01-05 00:00:00

abstract：:Heating on the microscale using focused lasers gave rise to recent applications, e.g., in biomedicine, biology and microfluidics, especially using gold nanoparticles as efficient nanoabsorbers of light. However, such an approach naturally leads to nonuniform, Gaussian-like temperature distributions due to the diffusiv...

journal_title：Scientific reports

authors： Durdevic L,Robert HML,Wattellier B,Monneret S,Baffou G

更新日期：2019-03-15 00:00:00

abstract：:The accumulation of repetitive DNA sequences on the sex-limited W or Y chromosomes is a well-known process that is likely triggered by the suppression of recombination between the sex chromosomes, which leads to major differences in their sizes and genetic content. Here, we report an analysis conducted on the satellit...

journal_title：Scientific reports

authors： Utsunomia R,Silva DMZA,Ruiz-Ruano FJ,Goes CAG,Melo S,Ramos LP,Oliveira C,Porto-Foresti F,Foresti F,Hashimoto DT

更新日期：2019-04-10 00:00:00

abstract：:Rapid, sensitive, point-of-care diagnostics are critical for managing infectious diseases. Here we adapt the CRISPR-based SHERLOCK method to develop a rapid, accurate, single copy detection assay for White Spot Syndrome Virus, the most devastating virus impacting global shrimp aquaculture. Further, we combine paper ma...

journal_title：Scientific reports

authors： Sullivan TJ,Dhar AK,Cruz-Flores R,Bodnar AG

更新日期：2019-12-23 00:00:00

abstract：:Low-noise millimetre-wave signals are valuable for digital sampling systems, arbitrary waveform generation for ultra-wideband communications, and coherent radar systems. However, the phase noise of widely used conventional signal generators (SGs) will increase as the millimetre-wave frequency increases. Our goal has b...

journal_title：Scientific reports

authors： Ishizawa A,Nishikawa T,Goto T,Hitachi K,Sogawa T,Gotoh H

更新日期：2016-05-17 00:00:00

abstract：:β-Lactamases are a major threat to the clinical use of carbapenems, which are often antibiotics of last resort. Despite this, the reaction outcomes and mechanisms by which β-lactamases degrade carbapenems are still not fully understood. The carbapenem bicyclic core consists of a β-lactam ring fused to a pyrroline ring...

journal_title：Scientific reports

authors： Lohans CT,Freeman EI,Groesen EV,Tooke CL,Hinchliffe P,Spencer J,Brem J,Schofield CJ

更新日期：2019-09-20 00:00:00

abstract：:Etoposide (ETO) is a commonly used chemotherapeutic drug that inhibits topoisomerase II activity, thereby leading to genotoxicity and cytotoxicity. However, ETO has limited application due to its side effects on normal organs, especially the kidney. Here, we report the mechanism of ETO-induced cytotoxicity progression...

journal_title：Scientific reports

authors： Shin HJ,Kwon HK,Lee JH,Anwar MA,Choi S

更新日期：2016-09-26 00:00:00

abstract：:One fundamental question in prey luring systems is to understand how visual signals are interpreted by the receiver. Predators lure prey by falsely imitating the signal of a model, or may exploit sensory preferences of the receivers, which search for rewarding signals. Crab spiders reflect ultraviolet (UV) light, ambu...

journal_title：Scientific reports

authors： Vieira C,Ramires EN,Vasconcellos-Neto J,Poppi RJ,Romero GQ

更新日期：2017-08-23 00:00:00

abstract：:N-methyl-D-aspartate (NMDA) receptors are glutamate- and glycine-gated channels composed of two GluN1 and two GluN2 or/and GluN3 subunits. GluN3A expression is developmentally regulated, and changes in this normal pattern of expression, which occur in several brain disorders, alter synaptic maturation and function by ...

journal_title：Scientific reports

authors： Cummings KA,Popescu GK

更新日期：2016-03-22 00:00:00

abstract：:In recent years, there is a growing interest towards the green synthesis of metal nanoparticles, particularly from plants; however, yet no published study on the synthesis of ZnO.NPs using the Deverra tortuosa extract. Through this study, zinc oxide nanoparticles (ZnO.NPs) have been synthesized based on using the envi...

journal_title：Scientific reports

authors： Selim YA,Azb MA,Ragab I,H M Abd El-Azim M

更新日期：2020-02-26 00:00:00

abstract：:Repeated social defeat stress (R-SDS) induces multiple behavioral changes in mice. However, the relationships between these behavioral changes were not fully understood. In the first experiment, to examine how the social avoidance is related to R-SDS-impaired behavioral flexibility, 10-week-old male C57BL/6N mice rece...

journal_title：Scientific reports

authors： Higashida S,Nagai H,Nakayama K,Shinohara R,Taniguchi M,Nagai M,Hikida T,Yawata S,Ago Y,Kitaoka S,Narumiya S,Furuyashiki T

更新日期：2018-07-11 00:00:00

abstract：:An in-depth focused study of specific cases of patients with recurrent thrombosis may help to identify novel circumstances, genetic and acquired factors contributing to the development of this disorder. The aim of this study was to carry out a detailed and sequential analysis of samples from a patient suffering from e...

journal_title：Scientific reports

authors： Revilla N,de la Morena-Barrio ME,Miñano A,López-Gálvez R,Toderici M,Padilla J,García-Avello Á,Lozano ML,Lefeber DJ,Corral J,Vicente V

更新日期：2017-03-17 00:00:00

abstract：:Biosynthesis of sakuranetin, a flavonoid anti-fungal phytoalexin that occurs in rice, is highly dependent on jasmonic acid (JA) signalling and induced by a variety of environmental stimuli. We previously identified OsNOMT, which encodes naringenin 7-O-methyltransferase (NOMT); NOMT is a key enzyme for sakuranetin prod...

journal_title：Scientific reports

authors： Ogawa S,Miyamoto K,Nemoto K,Sawasaki T,Yamane H,Nojiri H,Okada K

更新日期：2017-01-09 00:00:00