Rapid, CRISPR-Based, Field-Deployable Detection Of White Spot Syndrome Virus In Shrimp.

abstract：:Plant diseases are a major cause for yield losses and new strategies to control them without harming the environment are urgently needed. Plant-associated bacteria contribute to their host's health in diverse ways, among which the emission of disease-inhibiting volatile organic compounds (VOCs). We have previously rep...

journal_title：Scientific reports

authors： Chinchilla D,Bruisson S,Meyer S,Zühlke D,Hirschfeld C,Joller C,L'Haridon F,Mène-Saffrané L,Riedel K,Weisskopf L

更新日期：2019-12-30 00:00:00

abstract：:Alzheimer's disease (AD) is the most common form of dementia characterized by the formation of amyloid plaques (Aβ). Over the last decade, the important role of the innate immune system for the disease development has been established. Chronic activation of microglial cells creates a proinflammatory environment, which...

journal_title：Scientific reports

authors： Boza-Serrano A,Yang Y,Paulus A,Deierborg T

更新日期：2018-01-24 00:00:00

abstract：:Low phase noise mode-locked fiber laser finds important applications in telecommunication, ultrafast sciences, material science, and biology, etc. In this paper, two types of carbon nano-materials, i.e. single-wall carbon nanotube (SWNT) and graphene oxide (GO), are investigated as efficient saturable absorbers (SAs) ...

journal_title：Scientific reports

authors： Li X,Wu K,Sun Z,Meng B,Wang Y,Wang Y,Yu X,Yu X,Zhang Y,Shum PP,Wang QJ

更新日期：2016-04-29 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： El-Nahhal IM,Salem J,Anbar R,Kodeh FS,Elmanama A

更新日期：2020-05-27 00:00:00

abstract：:Neuroinflammation in utero may result in life-long neurological disabilities. Microglia play a pivotal role, but the mechanisms are poorly understood. No early postnatal treatment strategies exist to enhance neuroprotective potential of microglia. We hypothesized that agonism on α7 nicotinic acetylcholine receptor (α7...

journal_title：Scientific reports

authors： Cortes M,Cao M,Liu HL,Moore CS,Durosier LD,Burns P,Fecteau G,Desrochers A,Barreiro LB,Antel JP,Frasch MG

更新日期：2017-09-06 00:00:00

abstract：:Photosensitizer protoporphyrin IX (PpIX) fluorescence, intracellular localization and cell response to photodynamic therapy (PDT) were analyzed in MCF10A normal breast epithelial cells and a panel of human breast cancer cells including estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) po...

journal_title：Scientific reports

authors： Palasuberniam P,Yang X,Kraus D,Jones P,Myers KA,Chen B

更新日期：2015-08-18 00:00:00

abstract：:Treatment of azo dye effluents has received increasing concerns over the years due to their potential harms to natural environment and human health. The present study described the degrading ability of the as-synthesized crystalline Al-Cu alloys for removal of high-concentration Acid Scarlet 3R in alkaline aqueous sol...

journal_title：Scientific reports

authors： Zhang L,Gao X,Zhang Z,Zhang M,Cheng Y,Su J

更新日期：2016-08-18 00:00:00

abstract：:The endo-levanase BT1760 of a human gut commensal Bacteroides thetaiotaomicron randomly cuts a β-2,6-linked fructan, levan, into fructo-oligosaccharides providing a prebiotic substrate for gut microbiota. Here we introduce the crystal structure of BT1760 at resolution of 1.65 Å. The fold of the enzyme is typical for G...

journal_title：Scientific reports

authors： Ernits K,Eek P,Lukk T,Visnapuu T,Alamäe T

更新日期：2019-06-11 00:00:00

abstract：:The aim of this study was to identify mRNA targets of dysregulated miRNAs through the integrated analysis of miRNA and mRNA expression profiling in men with normal versus impaired spermatogenesis. The expression of mRNAs and miRNAs in testicular tissues obtained from males with non-obstructive azoospermia (NOA, n = 4)...

journal_title：Scientific reports

authors： Zhuang X,Li Z,Lin H,Gu L,Lin Q,Lu Z,Tzeng CM

更新日期：2015-01-28 00:00:00

abstract：:The pollination syndrome concept has provided powerful utility in understanding the evolution and adaptation of floral traits. However, the utility of this conception has been questioned on the grounds that flowers usually attract a broader spectrum of visitors than one might expect. Furthermore, the relationship betw...

journal_title：Scientific reports

authors： Wang X,Wen M,Qian X,Pei N,Zhang D

更新日期：2020-08-18 00:00:00

abstract：:The pentameric serum IgMs are critical to immune defense and surveillance through cytotoxicity against microbes and nascent cancer cells. Ficolins, a group of oligomeric lectins with an overall structure similar to C1q and mannose-binding lectin (MBL) participate in microbe infection and apoptotic cell clearance by ac...

journal_title：Scientific reports

authors： Lei X,Liu C,Azadzoi K,Li C,Lu F,Xiang A,Sun J,Guo Y,Zhao Q,Yan Z,Yang J

更新日期：2015-01-16 00:00:00

abstract：:A simple, environmentally friendly and cost-effective nonsurfactant template method was used to synthesize tannic-acid-templated mesoporous silica nanoparticles (TMSNs), and then dopamine functionalized TMSNs (Dop-TMSNs) which was synthesized by a facile and biomimetic coating strategy, was developed as a new sorbent ...

journal_title：Scientific reports

authors： Gao J,Lei H,Han Z,Shi Q,Chen Y,Jiang Y

更新日期：2017-03-22 00:00:00

abstract：:When multiple information are spread on social networks, there may be Cooperation and Competition among these information. Based on a new spreading model of multiple information, we studied Cooperation and Competition in information spreading, and analyzed the influence of different factors on Cooperation and Competit...

journal_title：Scientific reports

authors： Zhu Z,Gao C,Zhang Y,Li H,Xu J,Zan Y,Li Z

更新日期：2020-07-22 00:00:00

abstract：:Supercontinuum generation in Kerr media has become a staple of nonlinear optics. It has been celebrated for advancing the understanding of soliton propagation as well as its many applications in a broad range of fields. Coherent spectral broadening of laser light is now commonly performed in laboratories and used in c...

journal_title：Scientific reports

authors： Ciret C,Gorza SP,Husko C,Roelkens G,Kuyken B,Leo F

更新日期：2018-11-21 00:00:00

abstract：:Gastroenterologists are still unable to differentiate between some of the most ordinary disorders of the gut and consequently patients are misdiagnosed. We have developed a swallowable gas sensor capsule for addressing this. The gases of the gut are the by-product of the fermentation processes during digestion, affect...

journal_title：Scientific reports

authors： Ou JZ,Cottrell JJ,Ha N,Pillai N,Yao CK,Berean KJ,Ward SA,Grando D,Muir JG,Harrison CJ,Wijesiriwardana U,Dunshea FR,Gibson PR,Kalantar-Zadeh K

更新日期：2016-09-16 00:00:00

abstract：:Demand is increasing for superhydrophobic materials in many applications, such as membrane distillation, separation and special coating technologies. In this study, we report a chemical vapor deposition (CVD) process to fabricate superhydrophobic carbon nanomaterials (CNM) on nickel (Ni)-doped powder activated carbon ...

journal_title：Scientific reports

authors： Aljumaily MM,Alsaadi MA,Das R,Hamid SBA,Hashim NA,AlOmar MK,Alayan HM,Novikov M,Alsalhy QF,Hashim MA

更新日期：2018-02-09 00:00:00

abstract：:Inhaled corticosteroids (ICSs) are widely prescribed in chronic obstructive pulmonary disease (COPD). However, little is known about predictors of ICSs therapeutic response. To investigate whether the variation in glucocorticoid-induced transcript 1 (GLCCI1) rs37973 is associated with ICS efficacy. A total of 204 clin...

journal_title：Scientific reports

authors： Lei Y,Gao Y,Chen J,Li M,Wu X,Ning Q,Zhao J,Xiong W,Xu Y,Xie J

更新日期：2017-02-10 00:00:00

abstract：:The biggest challenge in colorectal cancer therapy is to avoid intestinal drug absorption before reaching the colon, while focusing on tumor specific delivery with high local concentration and minimal toxicity. In our work, thymoquinone (TQ)-loaded polymeric nanocapsules were prepared using the nanoprecipitation techn...

journal_title：Scientific reports

authors： Ramzy L,Metwally AA,Nasr M,Awad GAS

更新日期：2020-07-03 00:00:00

abstract：:The ability to measure biomolecular dynamics within cells and tissues is very important to understand fundamental physiological processes including cell adhesion, signalling, movement, division or metabolism. Usually, such information is obtained using particle tracking methods or single point fluctuation spectroscopy...

journal_title：Scientific reports

authors： Hedde PN,Stakic M,Gratton E

更新日期：2014-11-14 00:00:00

abstract：:Intestinal-type sinonasal adenocarcinoma (ITAC) is a rare tumor carrying poor prognosis and needing new treatment options. The aim of this study was to identify actionable gene mutations that can guide new personalized target-specific therapies in ITAC patients. A series of 48 tumor and 27 corresponding germline DNA s...

journal_title：Scientific reports

authors： Sánchez-Fernández P,Riobello C,Costales M,Vivanco B,Cabal VN,García-Marín R,Suárez-Fernández L,López F,Cabanillas R,Hermsen MA,Llorente JL

更新日期：2021-01-26 00:00:00

abstract：:The excessive release and accumulation of glutamate in the brain is known to be associated with excitotoxicity. CE, an extract derived from the plant Coeloglossum viride var. Bracteatum, exerted neuroprotective effects against amyloid toxicity and oxidative stress in cortical neurons. The aims of this study are to exa...

journal_title：Scientific reports

authors： Pan RY,Ma J,Wu HT,Liu QS,Qin XY,Cheng Y

更新日期：2017-08-23 00:00:00

abstract：:To effectively manage a watershed and successfully restore a river system, it is very important to assess the toxicity of sediments and identify the substances causing the toxicity. Seventy-six sediments collected in the Haihe River Basin (HRB) in China were screened for acute toxicity using Chironomus dilutus. We fou...

journal_title：Scientific reports

authors： Zhu X,Shan B,Tang W,Zhang C

更新日期：2017-05-03 00:00:00

abstract：:The natural peptide chensinin-1 doesnot exhibit its desired biological properties. In this study, the mutant MC1-1 was designed by replacing Gly in the chensinin-1 sequence with Trp. Mutants MC1-2 and MC1-3 were designed based on the MC1-1 sequence to investigate the specific role of His residues. The mutated peptides...

journal_title：Scientific reports

authors： Dong W,Mao X,Guan Y,Kang Y,Shang D

更新日期：2017-01-05 00:00:00

abstract：:Cancer patients often use dietary supplements while on therapy, but little is known about interactions of supplements with cancer chemotherapy. Black raspberries (BRB) have anti-cancer effects, but have not been evaluated for interference with chemotherapy for castrate-resistant prostate cancer (CRPC). Here we studied...

journal_title：Scientific reports

authors： Eskra JN,Schlicht MJ,Bosland MC

更新日期：2019-03-13 00:00:00

abstract：:Somatic copy number alterations (SCNAs) affecting oncogenic drivers have a firmly established role in promoting cancer. However, no agreed-upon standard exists for calling locus-specific amplifications and deletions in each patient sample. Here, we report the correlative analysis of copy number amplitude and length wi...

journal_title：Scientific reports

authors： Roszik J,Wu CJ,Siroy AE,Lazar AJ,Davies MA,Woodman SE,Kwong LN

更新日期：2016-01-20 00:00:00

abstract：:In higher plants, L-galactono-1,4-lactone dehydrogenase (GLDH) plays important roles in ascorbic acid (AsA) biosynthesis and assembly of respiration complex I. Here we report three homoeologous genes (TaGLDH-A1, -B1 and -D1) encoding common wheat GLDH isozymes and a unique allelic variant (TaGLDH-A1b) associated with ...

journal_title：Scientific reports

authors： Zhang J,Li B,Yang Y,Mu P,Qian W,Dong L,Zhang K,Liu X,Qin H,Ling H,Wang D

更新日期：2016-07-22 00:00:00

abstract：:The purpose of this paper is to develop a lightweight apron that will be used for shielding low intensity radiation in medical imaging radiography room and to apply it to a custom-made effective shielding. The quality of existing aprons made for protecting our bodies from direct radiation are improved so that they are...

journal_title：Scientific reports

authors： Kim SC,Choi JR,Jeon BK

更新日期：2016-07-27 00:00:00

abstract：:The Tarim Basin is regarded as one of the most highly erodible areas in China. Desert comprises 64% of the land use in the Basin, but the desert-oasis ecotone plays a prominent role in maintaining oasis ecological security and stability. Yet, little is known concerning the magnitude of windblown sediment transport in ...

journal_title：Scientific reports

authors： Pi H,Sharratt B,Lei J

更新日期：2017-08-10 00:00:00

abstract：:The gene encoding the cytosolic β-glucosidase GBA3 shows pseudogenization due to a truncated allele (rs358231) that is polymorphic in humans. Since this enzyme is involved in the transformation of many plant β-glycosides, this particular case of gene loss may have been influenced by dietary adaptations during evolutio...

journal_title：Scientific reports

authors： Lopes-Marques M,Serrano C,Cardoso AR,Salazar R,Seixas S,Amorim A,Azevedo L,Prata MJ

更新日期：2020-07-14 00:00:00

abstract：:p53 and aldehyde dehydrogenase (ALDH) have been implicated in key tumorigenesis processes including cancer initiating cell (CIC) maintenance; however, the relationship between these two mediators remains poorly defined. In this study, ALDH isoform expression diversity was revealed in CICs with disparate p53 functional...

journal_title：Scientific reports

authors： Gui S,Xie X,O'Neill WQ,Chatfield-Reed K,Yu JG,Teknos TN,Pan Q

更新日期：2020-01-23 00:00:00