Efficient microbial production of stylopine using a Pichia pastoris expression system.

abstract：:Which factors are related to false negative results of the interferon-γ release assay (IGRA) is unclear. This systematic review described the risk factors associated with false negative IGRA results. Two authors independently identified studies designed to evaluate risk factors for false negative IGRA results from Pub...

journal_title：Scientific reports

authors： Yamasue M,Komiya K,Usagawa Y,Umeki K,Nureki SI,Ando M,Hiramatsu K,Nagai H,Kadota JI

更新日期：2020-01-31 00:00:00

abstract：:Toxins are believed to play a crucial role in Burkholderia pseudomallei pathogenicity, however to date, only a few have been identified. The discovery of additional toxic molecules is limited by the lack of a sensitive indicator of B. pseudomallei toxicity. Previously, from a whole genome transcriptome analysis of B. ...

journal_title：Scientific reports

authors： Wong RR,Kong C,Lee SH,Nathan S

更新日期：2016-06-07 00:00:00

abstract：:Ovarian cancer is one of the leading causes of death in gynecological malignancies, and the resistance to chemotherapeutic agents remains a major challenge to successful ovarian cancer chemotherapy. Dihydromyricetin (DHM), a natural flavonoid derived from Ampeopsis Grossdentata, has been widely applied in food industr...

journal_title：Scientific reports

authors： Xu Y,Wang S,Chan HF,Lu H,Lin Z,He C,Chen M

更新日期：2017-04-24 00:00:00

abstract：:Lavender (Lavandula angustifolia) is an important economic plant because of the value of its essential oil (EO). The Yili Valley in Xinjiang has become the largest lavender planting base in China. However, there is a lack of research on the gene expression regulation of EO biosynthesis and metabolism in local varietie...

journal_title：Scientific reports

authors： Guo D,Kang K,Wang P,Li M,Huang X

更新日期：2020-04-24 00:00:00

abstract：:Although the perception of faces depends on low-level neuronal processes, it is also affected by high-level social processes. Faces from a social in-group, such as people of a similar age, receive more in-depth processing and are processed holistically. To explore whether own-age biases affect subconscious face percep...

journal_title：Scientific reports

authors： Nicholls MER,Churches O,Loetscher T

更新日期：2018-08-23 00:00:00

abstract：:Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is thought to be a pure genetic form of subcortical vascular cognitive impairment (SVCI). The aim of this study was to compare white matter integrity and cortical thickness between typical CADASIL, a genetic form, and ...

journal_title：Scientific reports

authors： Kim KW,Kwon H,Kim YE,Yoon CW,Kim YJ,Kim YB,Lee JM,Yoon WT,Kim HJ,Lee JS,Jang YK,Kim Y,Jang H,Ki CS,Youn YC,Shin BS,Bang OY,Kim GM,Chung CS,Kim SJ,Na DL,Duering M,Cho H,Seo SW

更新日期：2019-01-28 00:00:00

abstract：:RNA is transcribed from DNA, and therefore, there should be no RNA transcript from the deleted DNA region. Our study attempted to analyse whether any RNA cache that maps the deleted regions is present in human cells. Using data from the 1000 genome project, we selected 41 CEPH (CEU) and 38 Yoruba (YRI) samples that in...

journal_title：Scientific reports

authors： Byeon B,Kovalchuk I

更新日期：2016-11-17 00:00:00

abstract：:The loss of retinal pericytes (RPCs) is a hallmark of early stage diabetic retinopathy (DR), but the mechanism underlying RPC death is unclear. Although it was postulated in previous studies using bovine RPCs that autoantibodies against RPCs might develop and induce RPC death, it is unknown whether autoantibodies agai...

journal_title：Scientific reports

authors： Zhang L,Li Y,Payne J,Srivastava S,Fan X,Fung J,Li X,Kern TS,Lin F

更新日期：2016-02-03 00:00:00

abstract：:Structural neuroimaging studies of posttraumatic stress disorder (PTSD) have typically reported reduced cortical thickness (CT) and gray matter volume (GMV) in subcortical structures and networks involved in memory retrieval, emotional processing and regulation, and fear acquisition and extinction. Although PTSD is mo...

journal_title：Scientific reports

authors： Crombie KM,Ross MC,Letkiewicz AM,Sartin-Tarm A,Cisler JM

更新日期：2021-01-19 00:00:00

abstract：:High content of organic matter in the downstream of watersheds underscored the severity of non-point source (NPS) pollution. The major objectives of this study were to characterize and quantify dissolved organic matter (DOM) in watersheds affected by NPS pollution, and to apply self-organizing map (SOM) and parallel f...

journal_title：Scientific reports

authors： Zhang Y,Liang X,Wang Z,Xu L

更新日期：2015-11-03 00:00:00

abstract：:The effect of the surface area of palm kernel shell activated carbon (PKSAC) on the properties of n-octadecane-encapsulated shape stabilized phase change material (SSPCM) for thermal energy storage (TES) application were studied. Various surface areas of the PKSAC were prepared using different amounts of H3PO4 treatme...

journal_title：Scientific reports

authors： Nicholas AF,Hussein MZ,Zainal Z,Khadiran T

更新日期：2020-09-14 00:00:00

abstract：:Highly efficient and specific biomolecular recognition requires both affinity and specificity. Previous quantitative descriptions of biomolecular recognition were mostly driven by improving the affinity prediction, but lack of quantification of specificity. We developed a novel method SPA (SPecificity and Affinity) ba...

journal_title：Scientific reports

authors： Yan Z,Wang J

更新日期：2012-01-01 00:00:00

abstract：:Surface defect of nanomaterials is an important physical parameter which significantly influences their physical and chemical performances. In this work, high concentration of surface oxygen vancancies (SOVs) are successfully introduced on {001} facets exposed BiOBr nanosheets via a simple surface modification using p...

journal_title：Scientific reports

authors： Wang XJ,Zhao Y,Li FT,Dou LJ,Li YP,Zhao J,Hao YJ

更新日期：2016-04-26 00:00:00

abstract：:Enhancement of endogenous neurogenesis after ischemic stroke may improve functional recovery. We previously demonstrated that medium B, which is a combination with epidermal growth factor (EGF) and fibronectin, can promote neural stem/progenitor cell (NSPC) proliferation and migration. Here, we showed that medium B pr...

journal_title：Scientific reports

authors： Chen YA,Tsai YC,Chen YD,Liu DZ,Young TH,Tsai LK

更新日期：2020-04-20 00:00:00

abstract：:Glycoprotein nonmetastatic melanoma protein B (GPNMB) plays important roles in various types of cancer and amyotrophic lateral sclerosis (ALS). The details of GPNMB function and its interacting protein have not been clarified. Therefore, to identify GPNMB binding partners on the cell membrane, we used membrane protein...

journal_title：Scientific reports

authors： Ono Y,Tsuruma K,Takata M,Shimazawa M,Hara H

更新日期：2016-03-18 00:00:00

abstract：:Prostate-specific antigen (PSA) kinetics predicts survival in castration-resistant prostate cancer (CRPC); however, the influence of prior treatment on this relationship is unclear. Patients with CRPC were stratified according to time to PSA nadir and time to CRPC progression to investigate their prognostic significan...

journal_title：Scientific reports

authors： Hah YS,Lee JS,Rha KH,Hong SJ,Chung BH,Koo KC

更新日期：2019-08-15 00:00:00

abstract：:We explore the effect of temperature on the interaction of polydisperse mixtures of nonionic poly(ethylene glycol) (PEG) polymers of different average molar masses with the biological nanopore α-hemolysin. In contrast with what has been previously observed with various nanopores and analytes, we find that, for PEGs la...

journal_title：Scientific reports

authors： Piguet F,Ouldali H,Discala F,Breton MF,Behrends JC,Pelta J,Oukhaled A

更新日期：2016-12-07 00:00:00

abstract：:Cell lytic enzymes represent an alternative to chemical decontamination or use of antibiotics to kill pathogenic bacteria, such as listeria. A number of phage cell lytic enzymes against listeria have been isolated and possess listericidal activity; however, there has been no attempt to incorporate these enzymes onto s...

journal_title：Scientific reports

authors： Solanki K,Grover N,Downs P,Paskaleva EE,Mehta KK,Lee L,Schadler LS,Kane RS,Dordick JS

更新日期：2013-01-01 00:00:00

abstract：:Glucose homeostasis is regulated by insulin, which is produced in the β-cells of the pancreas. The synthesis of insulin is controlled by several transcription factors including PDX-1, USF1 and USF2. Both, PDX-1 and USF1 were identified as substrates for protein kinase CK2. Here, we have analysed the interplay of PDX-1...

journal_title：Scientific reports

authors： Spohrer S,Groß R,Nalbach L,Schwind L,Stumpf H,Menger MD,Ampofo E,Montenarh M,Götz C

更新日期：2017-11-27 00:00:00

abstract：:Polyphenol oxidases (PPOs) contain the structurally similar enzymes tyrosinases (TYRs) and catechol oxidases (COs). Two cDNAs encoding pro-PPOs from tomato (Solanum lycopersicum) were cloned and heterologously expressed in Escherichia coli. The two pro-PPOs (SlPPO1-2) differ remarkably in their activity as SlPPO1 reac...

journal_title：Scientific reports

authors： Kampatsikas I,Bijelic A,Rompel A

更新日期：2019-03-11 00:00:00

abstract：:Anatomically realistic organ replicas or phantoms allow for accurate studies and reproducible research. To recreate a human kidney, mimicry of the elastic properties of the human kidney is crucial. However, none of the related work addressed the design and development of a kidney phantom using only silicone as materia...

journal_title：Scientific reports

authors： Hattab G,Ahlfeld T,Klimova A,Koepp A,Schuerer M,Speidel S

更新日期：2020-07-16 00:00:00

abstract：:Secondary ion mass spectrometry is an excellent technique of analytical chemistry, where primary ions sputter a solid sample generating the secondary ions which are determined. Although the ion yield is inherently low, it can be enhanced by using a post-ionization of sputtered neutral species. Our novel approach integ...

journal_title：Scientific reports

authors： Lorenc D,Jerigova M,Stupavska M,Velic D

更新日期：2017-07-20 00:00:00

abstract：:α-Dystroglycanopathy (α-DGP) is a group of muscular dystrophy characterized by abnormal glycosylation of α-dystroglycan (α-DG), including Fukuyama congenital muscular dystrophy (FCMD), muscle-eye-brain disease, Walker-Warburg syndrome, and congenital muscular dystrophy type 1D (MDC1D), etc. LARGE, the causative gene f...

journal_title：Scientific reports

authors： Ohtsuka Y,Kanagawa M,Yu CC,Ito C,Chiyo T,Kobayashi K,Okada T,Takeda S,Toda T

更新日期：2015-02-09 00:00:00

abstract：:High-grade gliomas are the most aggressive malignant brain tumors. Accurate pre-operative prognosis for this cohort can lead to better treatment planning. Conventional survival prediction based on clinical information is subjective and could be inaccurate. Recent radiomics studies have shown better prognosis by using ...

journal_title：Scientific reports

authors： Nie D,Lu J,Zhang H,Adeli E,Wang J,Yu Z,Liu L,Wang Q,Wu J,Shen D

更新日期：2019-01-31 00:00:00

abstract：:Bacterial vaginosis (BV) is associated with HIV acquisition and adverse pregnancy outcomes. Recurrence after metronidazole treatment is high. HIV-negative, non-pregnant Rwandan BV patients were randomized to four groups (n = 17/group) after seven-day oral metronidazole treatment: behavioral counseling only (control), ...

journal_title：Scientific reports

authors： van de Wijgert JHHM,Verwijs MC,Agaba SK,Bronowski C,Mwambarangwe L,Uwineza M,Lievens E,Nivoliez A,Ravel J,Darby AC

更新日期：2020-03-03 00:00:00

abstract：:To ensure the reliability of the planned multi-center clinical trial, we assessed the consistence and comparability of the quantitative parameters of the eight PET/CT units that will be used in this trial. PET/CT images were scanned using a PET NEMA image quality phantom (Biodex) on the eight units of Discovery PET/CT...

journal_title：Scientific reports

authors： Zhu Y,Geng C,Huang J,Liu J,Wu N,Xin J,Xu H,Yu L,Geng J

更新日期：2018-06-13 00:00:00

abstract：:We demonstrate fluorescent Fe embedded magnetic nanodiamonds by ion implantation and two-step annealing. The diamond characteristics with a highly ordered core and a graphite surface layer are maintained after the implantation process. After the two-step annealing process, a bright red fluorescence associated with nit...

journal_title：Scientific reports

authors： Lin BR,Kunuku S,Chen CH,Chen TY,Hsiao TY,Yu HK,Chang YJ,Liao LC,Niu H,Lee CP

更新日期：2019-02-04 00:00:00

abstract：:Biomimetic scaffolds are of great interest to tissue engineering (TE) and tissue repair as they support important cell functions. Scaffold coating with soluble collagen-I has been used to achieve better tissue integration in orthopaedy, however, as collagen persistence was only temporary such efforts were limited. Ade...

journal_title：Scientific reports

authors： Vielreicher M,Kralisch D,Völkl S,Sternal F,Arkudas A,Friedrich O

更新日期：2018-06-20 00:00:00

abstract：:A fluorimetric Hg2+ test strip has been developed using a lotus-inspired fabrication method for suppressing the "coffee stains" toward the uniform distribution of probe materials through creating a hydrophobic drying pattern for fast solvent evaporation. The test strips were first loaded with the model probes of fluor...

journal_title：Scientific reports

authors： Qiao Y,Shang J,Li S,Feng L,Jiang Y,Duan Z,Lv X,Zhang C,Yao T,Dong Z,Zhang Y,Wang H

更新日期：2016-11-04 00:00:00

abstract：:Living organisms have to adjust to their surrounding in order to survive in stressful conditions. We study this mechanism in one of most primitive creatures - photosynthetic green sulfur bacteria. These bacteria absorb photons very efficiently using the chlorosome antenna complexes and perform photosynthesis in extrem...

journal_title：Scientific reports

authors： Saikin SK,Khin Y,Huh J,Hannout M,Wang Y,Zare F,Aspuru-Guzik A,Tang JK

更新日期：2014-05-27 00:00:00