Impact of DNA extraction method and targeted 16S-rRNA hypervariable region on oral microbiota profiling.

abstract：:Learning a skilled movement often requires changing multiple dimensions of movement in a coordinated manner. Serial training is one common approach to learning a new movement pattern, where each feature is learned in isolation from the others. Once one feature is learned, we move on to the next. However, when learning...

journal_title：Scientific reports

authors： Day KA,Bastian AJ

更新日期：2019-12-24 00:00:00

abstract：:Coexistence of physical phenomena can occur in quite unexpected ways. Here we demonstrate the first evidence in any physical system of the coexistence in the same set of measurements of two of the most challenging phenomena in complex systems: turbulence and spin glasses. We employ a quasi-one-dimensional random fibre...

journal_title：Scientific reports

authors： González IRR,Raposo EP,Macêdo AMS,de S Menezes L,Gomes ASL

更新日期：2018-11-19 00:00:00

abstract：:Fibrosis with excessive amounts of type I collagen is a hallmark of many solid tumours, and fibrosis is a promising target in cancer therapy, but tools for its non-invasive quantification are missing. Here we used magnetic resonance imaging with a gadolinium-based probe targeted to type I collagen (EP-3533) to image a...

journal_title：Scientific reports

authors： Polasek M,Yang Y,Schühle DT,Yaseen MA,Kim YR,Sung YS,Guimaraes AR,Caravan P

更新日期：2017-08-14 00:00:00

abstract：:Heat stress threatens agriculture worldwide. Plants acquire heat stress tolerance through priming, which establishes stress memory during mild or severe transient heat stress. Such induced thermotolerance restructures metabolic networks and helps maintain metabolic homeostasis under heat stress. Here, we used an elect...

journal_title：Scientific reports

authors： Serrano N,Ling Y,Bahieldin A,Mahfouz MM

更新日期：2019-01-17 00:00:00

abstract：:The mechanism of immune tolerance is to be further understood. The present study aims to investigate the role of the Cardiac endothelial cell (CEC)-derived exosomes in the induction of regulatory B cells. In this study, CECs were isolated from the mouse heart. Exosomes were purified from the culture supernatant of the...

journal_title：Scientific reports

authors： Song J,Chen X,Wang M,Xing Y,Zheng Z,Hu S

更新日期：2014-12-23 00:00:00

abstract：:In this paper, the annually average Defense Meteorological Satellite Program-Operational Linescan System (DMSP/OLS) night-time light data is first proposed as a surrogate indicator to mine and forecast the average housing prices in the inland capital cities of China. First, based on the time-series analysis of individ...

journal_title：Scientific reports

authors： Li C,Zhu H,Ye X,Jiang C,Dong J,Wang D,Wu Y

更新日期：2020-05-07 00:00:00

abstract：:2-hydroxy-1,4 naphthoquinone (lawsone) is widely used and induces environmental pollutions during its production and application. In the present study, a lawsone-degrading bacterium strain, LH-3 was successfully isolated from the activated sludge. Based on the 16S rRNA gene analysis, the strain LH-3 phylogenetically b...

journal_title：Scientific reports

authors： Yang L,Cai T,Ding D,Cai T,Jiang C,Li H,Yang Q,Chen L

更新日期：2017-07-28 00:00:00

abstract：:Receipt of broad-spectrum antibiotics enhances Candida albicans colonization of the GI tract, a risk factor for haematogenously-disseminated candidiasis. To understand how antibiotics influence C. albicans colonization, we treated mice orally with vancomycin or a combination of penicillin, streptomycin, and gentamicin...

journal_title：Scientific reports

authors： Shankar J,Solis NV,Mounaud S,Szpakowski S,Liu H,Losada L,Nierman WC,Filler SG

更新日期：2015-02-03 00:00:00

abstract：:Understanding the role of morphogen in activating its target genes, otherwise epigenetically repressed, during change in cell fate specification is a very fascinating yet relatively unexplored domain. Our in vivo loss-of-function genetic analyses reveal that specifically during ectopic eye formation, the morphogen Dec...

journal_title：Scientific reports

authors： Aggarwal P,Gera J,Mandal L,Mandal S

更新日期：2016-06-07 00:00:00

abstract：:The CuO inverse opal photonic crystals (IOPCs) were synthesized by the sol-gel method and modified with CdS quantum dots by successive ionic layer adsorption and reaction (SILAR). CdS QDs modified CuO IOPCs FTO electrodes of different SILAR cycles were fabricated and their electrochemical properties were studied by cy...

journal_title：Scientific reports

authors： Xia L,Xu L,Song J,Xu R,Liu D,Dong B,Song H

更新日期：2015-06-04 00:00:00

abstract：:Radical cystectomy (RC) together with bilateral pelvic lymph node dissection remains the standard treatment for muscle invasive bladder cancer (MIBC). However, radiation-based treatments such as tri-modal therapy (TMT) involving maximally performed transurethral resection of bladder tumor (TURBT), radiotherapy (XRT), ...

journal_title：Scientific reports

authors： Ayoub M,Shinde-Jadhav S,Mansure JJ,Alvarez F,Connell T,Seuntjens J,Piccirillo CA,Kassouf W

更新日期：2019-04-23 00:00:00

abstract：:The Na+;HCO3- co-transporter NBCn1 (SLC4A7) is a major regulator of intracellular pH yet its trafficking and turnover are essentially unstudied. Here, we used MDCK-II and MCF-7 cells to investigate these processes in epithelial cells. GFP-NBCn1 membrane localization was abolished by truncation of the full NBCn1 C-term...

journal_title：Scientific reports

authors： Olesen CW,Vogensen J,Axholm I,Severin M,Schnipper J,Pedersen IS,von Stemann JH,Schrøder JM,Christensen DP,Pedersen SF

更新日期：2018-05-09 00:00:00

abstract：:CD31hiEmcnhi vessels were a subtype of vessels in the murine skeletal system, with high levels of platelet and endothelial cell adhesion molecule-1 (PECAM-1/CD31) and endomucin (Emcn). They were reported coupling angiogenesis and osteogenesis during bone development. We investigated the distribution of these vessels i...

journal_title：Scientific reports

authors： Wang J,Gao Y,Cheng P,Li D,Jiang H,Ji C,Zhang S,Shen C,Li J,Song Y,Cao T,Wang C,Yang L,Pei G

更新日期：2017-07-10 00:00:00

abstract：:Nanostructure arrays such as nanowire, nanopillar, and nanocone arrays have been proposed to be promising antireflection structures for photovoltaic applications due to their great light trapping ability. In this paper, the optical properties of Si nanopillar and nanocone arrays in visible and infrared region were stu...

journal_title：Scientific reports

authors： Wang ZY,Zhang RJ,Wang SY,Lu M,Chen X,Zheng YX,Chen LY,Ye Z,Wang CZ,Ho KM

更新日期：2015-01-15 00:00:00

abstract：:The Schumann Resonances (ScR) are Extremely Low Frequency (ELF) electromagnetic resonances in the Earth-ionosphere cavity excited by global lightning discharges. This natural electromagnetic noise has likely existed on the Earth ever since the Earth had an atmosphere and an ionosphere, hence surrounding us throughout ...

journal_title：Scientific reports

authors： Elhalel G,Price C,Fixler D,Shainberg A

更新日期：2019-02-07 00:00:00

abstract：:Copper ions play a vital role in a variety of fundamental physiological processes not only in human beings and plants, but also for extensive insects and microorganisms. In this paper, a novel water-soluble ruthenium(II) complex as a turn-on copper(II) ions luminescent sensor based on o-(phenylazo)aniline was designed...

journal_title：Scientific reports

authors： Zhang Y,Liu Z,Yang K,Zhang Y,Xu Y,Li H,Wang C,Lu A,Sun S

更新日期：2015-02-02 00:00:00

abstract：:The experimental approach for the study of cardiometabolic disorders requires the use of animal models fed with commercial diets whose composition differs notably, even between diets used for control groups. While chow diets are usually made of agricultural by-products, purified low-fat diets (LF) contain a higher per...

journal_title：Scientific reports

authors： González-Blázquez R,Alcalá M,Fernández-Alfonso MS,Villa-Valverde P,Viana M,Gil-Ortega M,Somoza B

更新日期：2020-02-19 00:00:00

abstract：:Left ventricular mass index (LVMI) increase has been described in hypertension (HTN), but less is known about its association with type 2 diabetes (T2DM). As these conditions frequently co-exist, we investigated the association of T2DM, HTN and both with echocardiographic parameters, and hypothesized that patients wit...

journal_title：Scientific reports

authors： Seferovic JP,Tesic M,Seferovic PM,Lalic K,Jotic A,Biering-Sørensen T,Giga V,Stankovic S,Milic N,Lukic L,Milicic T,Macesic M,Gajovic JS,Lalic NM

更新日期：2018-01-17 00:00:00

abstract：:AKT is an important signal transduction protein that plays a crucial role in cancer development. Therefore, we evaluated associations between single nucleotide polymorphisms (SNPs) in the AKT promoter region and gastric cancer (GCa) risk in a case-control study of 1,110 GCa patients and 1,114 matched cancer-free contr...

journal_title：Scientific reports

authors： Wang MY,He J,Zhu ML,Teng XY,Li QX,Sun MH,Wang XF,Yang YJ,Wang JC,Jin L,Wang YN,Wei QY

更新日期：2016-01-28 00:00:00

abstract：:Anserine/carnosine supplementation improves cerebral blood flow and verbal episodic memory in elderly people, as we previously reported. Anserine's buffering activity is superior to that of carnosine at neutral pH. In human sera, carnosine but not anserine is rapidly cleaved by carnosinase, limiting its effectiveness....

journal_title：Scientific reports

authors： Kaneko J,Enya A,Enomoto K,Ding Q,Hisatsune T

更新日期：2017-10-03 00:00:00

abstract：:Guanylate binding proteins (GBPs) belongs to the interferons (IFNs) induced guanylate-binding protein family (Guanosine triphosphatases, GTPases) consisting of seven homologous members, termed GBP1 to GBP7. We used multidimensional survey ways to explore GBPs expression, regulation, mutations, immune infiltration and ...

journal_title：Scientific reports

authors： Wu ZH,Cai F,Zhong Y

更新日期：2020-04-08 00:00:00

abstract：:Breast cancer transcriptome acquires a myriad of regulation changes, and splicing is critical for the cell to "tailor-make" specific functional transcripts. We systematically revealed splicing signatures of the three most common types of breast tumors using RNA sequencing: TNBC, non-TNBC and HER2-positive breast cance...

journal_title：Scientific reports

authors： Eswaran J,Horvath A,Godbole S,Reddy SD,Mudvari P,Ohshiro K,Cyanam D,Nair S,Fuqua SA,Polyak K,Florea LD,Kumar R

更新日期：2013-01-01 00:00:00

abstract：:An analysis of Candida albicans ABC transporters identified conserved related α-helical sequence motifs immediately C-terminal of each Walker A sequence. Despite the occurrence of these motifs in ABC subfamilies of other yeasts and higher eukaryotes, their roles in protein function remained unexplored. In this study w...

journal_title：Scientific reports

authors： Rawal MK,Banerjee A,Shah AH,Khan MF,Sen S,Saxena AK,Monk BC,Cannon RD,Bhatnagar R,Mondal AK,Prasad R

更新日期：2016-06-02 00:00:00

abstract：:Cartilage tissue is avascular and hypoxic which regulates chondrocyte phenotype via stabilization of HIFs. Here, we investigated the role of hypoxia and HIFs in regulation of Rho and canonical Wnt signaling in chondrocytes. Our data demonstrates that hypoxia controls the expression of RhoA in chondrocytes in a context...

journal_title：Scientific reports

authors： Öztürk E,Hobiger S,Despot-Slade E,Pichler M,Zenobi-Wong M

更新日期：2017-08-22 00:00:00

abstract：:To improve the grain yield of the lowland-adapted popular rice variety Samba Mahsuri under reproductive-stage drought (RS) and to understand the interactions between drought QTLs, two mapping populations were developed using marker-assisted selection (MAS) and marker-assisted recurrent selection (MARS). The mean grain...

journal_title：Scientific reports

authors： Sandhu N,Dixit S,Swamy BPM,Vikram P,Venkateshwarlu C,Catolos M,Kumar A

更新日期：2018-01-26 00:00:00

abstract：:Nuclei detection is often a critical initial step in the development of computer aided diagnosis and prognosis schemes in the context of digital pathology images. While over the last few years, a number of nuclei detection methods have been proposed, most of these approaches make idealistic assumptions about the stain...

journal_title：Scientific reports

authors： Lu C,Xu H,Xu J,Gilmore H,Mandal M,Madabhushi A

更新日期：2016-10-03 00:00:00

abstract：:An enormous amount of tumor sequencing data has been generated through large scale sequencing efforts. The functional consequences of the majority of mutations identified by such projects remain an open, unexplored question. This problem is particularly complicated in the case of rare mutations where frequency of occu...

journal_title：Scientific reports

authors： Katigbak A,Cencic R,Robert F,Sénécha P,Scuoppo C,Pelletier J

更新日期：2016-12-16 00:00:00

abstract：:The growing prevalence of resistance to antibiotics motivates the search for new antibacterial agents. Antimicrobial peptides are a diverse class of well-studied membrane-active peptides which function as part of the innate host defence system, and form a promising avenue in antibiotic drug research. Some antimicrobia...

journal_title：Scientific reports

authors： Timmons PB,Hewage CM

更新日期：2020-07-02 00:00:00

abstract：:We have explored the mechanical properties, electronic structures and phase transition behaviors of three designed new phases for element boron from ambient condition to high-pressure of 120 GPa including (1) a C2/c symmetric structure (m-B₁₆); (2) a symmetric structure (c-B₅₆) and (3) a Pmna symmetric structure (o-B₂...

journal_title：Scientific reports

authors： Fan C,Li J,Wang L

更新日期：2014-10-27 00:00:00

abstract：:Native collagen is arranged in bundles of aligned fibrils to withstand in vivo mechanical loads. Reproducing such a process under in vitro conditions has not met with major success. Our approach has been to induce nanolinks, during the self-assembly process, leading to delayed rather than inhibited fibrillogenesis. Fo...

journal_title：Scientific reports

authors： Nidhin M,Vedhanayagam M,Sangeetha S,Kiran MS,Nazeer SS,Jayasree RS,Sreeram KJ,Nair BU

更新日期：2014-08-06 00:00:00