Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products.

abstract：:To achieve a better understanding of the "vinegar syndrome" phenomenon, which has caused serious damage to triacetyl cellulose-based motion picture films, the white powder obtained from damaged film surfaces was analysed in this study. The powder was found to be soluble in acetone, diethyl ether, dimethylformamide, an...

journal_title：Scientific reports

authors： Takahashi K,Sasaki M,Hayakawa H,Yajima H,Oda Y

更新日期：2021-01-15 00:00:00

abstract：:Non-availability of an ideal alternative for autografts in treating critical-size bone defects is a major challenge in orthopedics. Phytocompounds have been proven to enhance osteogenesis via various osteogenic signaling pathways, but its decreased bioavailability and increased renal clearance limit its application. I...

journal_title：Scientific reports

authors： Chandran SV,Vairamani M,Selvamurugan N

更新日期：2019-08-15 00:00:00

abstract：:Mechanosensitive ion channels are pore-forming transmembrane proteins that allow ions to move down their electrochemical gradient in response to mechanical stimuli. They participate in many plant developmental processes including the maintenance of plastid shape, pollen tube growth, etc. Herein, a total of 11, 10, 6, ...

journal_title：Scientific reports

authors： Kaur A,Taneja M,Tyagi S,Sharma A,Singh K,Upadhyay SK

更新日期：2020-10-06 00:00:00

abstract：:Sweet potato leaf curl virus (SPLCV) causes yield losses in sweet potato cultivation. Diagnostic techniques such as serological detection have been developed because these plant viruses are difficult to treat. Serological assays have been used extensively with recombinant antibodies such as whole immunoglobulin or sin...

journal_title：Scientific reports

authors： Cho SH,Kil EJ,Cho S,Byun HS,Kang EH,Choi HS,Lee MG,Lee JS,Lee YG,Lee S

更新日期：2020-05-15 00:00:00

abstract：:Climate change is expected to have profound, partly unforeseeable effects on the composition of functional traits of complex ecosystems, such as coral reefs, and some ecosystem properties are at risk of disappearing. This study applies a novel spatially explicit, individual-based model to explore three critical life h...

journal_title：Scientific reports

authors： Kubicek A,Breckling B,Hoegh-Guldberg O,Reuter H

更新日期：2019-03-06 00:00:00

abstract：:Local drug delivery systems (DDS) have become a favourable approach for the treatment of numerous diseases. Biomedical imaging techniques such as ultrahigh field magnetic resonance imaging (UHF-MRI) offer unique insight into DDS biodegradation in vivo. We describe the establishment of a 7 Tesla MRI routine for longitu...

journal_title：Scientific reports

authors： Kopp F,Eickner T,Polei S,Falke K,Witt M,Grabow N,Stachs O,Guthoff RF,Lindner T

更新日期：2017-11-17 00:00:00

abstract：:Photosensitizer protoporphyrin IX (PpIX) fluorescence, intracellular localization and cell response to photodynamic therapy (PDT) were analyzed in MCF10A normal breast epithelial cells and a panel of human breast cancer cells including estrogen receptor (ER) positive, human epidermal growth factor receptor 2 (HER2) po...

journal_title：Scientific reports

authors： Palasuberniam P,Yang X,Kraus D,Jones P,Myers KA,Chen B

更新日期：2015-08-18 00:00:00

abstract：:OVGP1 is the major non-serum glycoprotein in the oviduct fluid at the time of fertilization and early embryo development. Its activity differs among species. Here, we show that the C-terminal region of recombinant OVGP1 regulates its binding to the extracellular zona pellucida and affects its activity during fertiliza...

journal_title：Scientific reports

authors： Algarra B,Han L,Soriano-Úbeda C,Avilés M,Coy P,Jovine L,Jiménez-Movilla M

更新日期：2016-09-07 00:00:00

abstract：:Kinases are involved in numerous critical cell signaling processes, and dysregulation in kinase signaling is implicated in many types of human cancers. In this study, we applied a parallel-reaction monitoring (PRM)-based targeted proteomic method to assess kinome reprogramming during melanoma metastasis in three pairs...

journal_title：Scientific reports

authors： Miao W,Li L,Liu X,Qi TF,Guo L,Huang M,Wang Y

更新日期：2020-02-12 00:00:00

abstract：:Recently, CuZr-based bulk metallic glass (BMG) composites reinforced by the TRIP (transformation-induced plasticity) effect have been explored in attempt to accomplish an optimal of trade-off between strength and ductility. However, the design of such BMG composites with advanced mechanical properties still remains a ...

journal_title：Scientific reports

authors： Qin YS,Han XL,Song KK,Tian YH,Peng CX,Wang L,Sun BA,Wang G,Kaban I,Eckert J

更新日期：2017-02-13 00:00:00

abstract：:Although the perception of faces depends on low-level neuronal processes, it is also affected by high-level social processes. Faces from a social in-group, such as people of a similar age, receive more in-depth processing and are processed holistically. To explore whether own-age biases affect subconscious face percep...

journal_title：Scientific reports

authors： Nicholls MER,Churches O,Loetscher T

更新日期：2018-08-23 00:00:00

abstract：:In this paper, we investigate the possibility of improving efficiency in non-radiative wireless power transfer (WPT) using metasurfaces embedded between two current varying coils and present a complete theoretical analysis of this system. We use a point-dipole approximation to calculate the fields of the coils. Based ...

journal_title：Scientific reports

authors： Younesiraad H,Bemani M

更新日期：2018-10-05 00:00:00

abstract：:Some previous studies have indicated that valproate (VPA) might change the pharmacokinetics and enhance the effects of propofol. We evaluated whether clinical VPA therapy affected the propofol blood level, the protein-unbound free propofol level, and/or the anesthetic effects of propofol in the clinical setting. The s...

journal_title：Scientific reports

authors： Kodama M,Higuchi H,Ishii-Maruhama M,Nakano M,Honda-Wakasugi Y,Maeda S,Miyawaki T

更新日期：2020-01-31 00:00:00

abstract：:In this paper, we present a strategy to improve delivery of femtosecond laser pulses from a regenerative amplifier through a hollow core photonic crystal fiber for temporally focused wide-field two-photon endomicroscopy. For endomicroscope application, wide-field two-photon excitation has the advantage of requiring no...

journal_title：Scientific reports

authors： Choi H,So PT

更新日期：2014-10-15 00:00:00

abstract：:One of the main characteristics of cancer tissues is poor development of neovascularization that results in a limited blood circulation. Because of this phenomenon, it is harder for cancer tissues to diffuse their elevated heat into other parts of the body. The scientific principle of radiofrequency hyperthermia relie...

journal_title：Scientific reports

authors： Chung HJ,Lee HK,Kwon KB,Kim HJ,Hong ST

更新日期：2018-09-10 00:00:00

abstract：:Elastic waves are guided along finite structures such as cylinders, plates, or rods through reflection, refraction, and mode conversion at the interfaces. Such wave propagation is ubiquitous in the world around us, and studies of elastic waveguides first emerged in the later part of the 19(th) century. Early work on e...

journal_title：Scientific reports

authors： Philippe FD,Murray TW,Prada C

更新日期：2015-06-08 00:00:00

abstract：:The high hydrophobicity of poly(vinylidene fluoride) (PVDF) membrane remains an obstacle to be applied in some purification processes of water or wastewater. Herein, a highly hydrophilic hybrid mesoporous titania membrane composed of mesoporous anatase titania (meso-TiO2) materials inside the three-dimensional (3D) ma...

journal_title：Scientific reports

authors： Wang M,Yang G,Jin P,Tang H,Wang H,Chen Y

更新日期：2016-01-12 00:00:00

abstract：:Holography--originally developed for correcting spherical aberration in transmission electron microscopes--is now used in a wide range of disciplines that involve the propagation of waves, including light optics, electron microscopy, acoustics and seismology. In electron microscopy, the two primary modes of holography...

journal_title：Scientific reports

authors： Ozsoy-Keskinbora C,Boothroyd CB,Dunin-Borkowski RE,van Aken PA,Koch CT

更新日期：2014-11-12 00:00:00

abstract：:Graphene, a two-dimensional structure of carbon, due to its structure has unique physico-chemical properties that can be used in numerous research and industry areas. Although this structure is already well known, there are still technological (and cost) barriers which do not allow to produce this material in large qu...

journal_title：Scientific reports

authors： Głuchowski P,Tomala R,Jeżowski A,Szewczyk D,Macalik B,Smolina I,Kurzynowski T,Stręk W

更新日期：2020-07-06 00:00:00

abstract：:Alpha synuclein (α-syn) is a central player in neurodegeneration, but the mechanisms triggering its pathology are not fully understood. Here we found that α-syn is a highly efficient substrate for arginyltransferase ATE1 and is arginylated in vivo by a novel mid-chain mechanism that targets the acidic side chains of E...

journal_title：Scientific reports

authors： Wang J,Han X,Leu NA,Sterling S,Kurosaka S,Fina M,Lee VM,Dong DW,Yates JR 3rd,Kashina A

更新日期：2017-09-12 00:00:00

abstract：:In endometriosis, M2 MΦs are dominant in endometriotic lesions, but the actual role of M2 MΦ is unclear. CD206 positive (+) MΦ is classified in one of M2 type MΦs and are known to produce cytokines and chemokines. In the present study, we used CD206 diphtheria toxin receptor mice, which enable to deplete CD206+ cells ...

journal_title：Scientific reports

authors： Ono Y,Yoshino O,Hiraoka T,Sato E,Furue A,Nawaz A,Hatta H,Fukushi Y,Wada S,Tobe K,Hirota Y,Osuga Y,Unno N,Saito S

更新日期：2021-01-13 00:00:00

abstract：:Joint action is essential in daily life, as humans often must coordinate with others to accomplish shared goals. Previous studies have mainly focused on sensorimotor aspects of joint action, with measurements reflecting event-to-event precision of interpersonal sensorimotor coordination (e.g., tapping). However, while...

journal_title：Scientific reports

authors： Chang A,Kragness HE,Livingstone SR,Bosnyak DJ,Trainor LJ

更新日期：2019-01-18 00:00:00

abstract：:Methods to repair bone defects arising from trauma, resection, or disease, continue to be sought after. Cyclic mechanical loading is well established to influence bone (re)modelling activity, in which bone formation and resorption are correlated to micro-scale strain. Based on this, the application of mechanical stimu...

journal_title：Scientific reports

authors： Malhotra A,Walle M,Paul GR,Kuhn GA,Müller R

更新日期：2021-01-21 00:00:00

abstract：:Radical cystectomy (RC) together with bilateral pelvic lymph node dissection remains the standard treatment for muscle invasive bladder cancer (MIBC). However, radiation-based treatments such as tri-modal therapy (TMT) involving maximally performed transurethral resection of bladder tumor (TURBT), radiotherapy (XRT), ...

journal_title：Scientific reports

authors： Ayoub M,Shinde-Jadhav S,Mansure JJ,Alvarez F,Connell T,Seuntjens J,Piccirillo CA,Kassouf W

更新日期：2019-04-23 00:00:00

abstract：:Regional abnormalities in brain structure and function, as well as disrupted connectivity, have been found repeatedly in adolescents with conduct disorder (CD). Yet, the large-scale brain topology associated with CD is not well characterized, and little is known about the systematic neural mechanisms of CD. We employe...

journal_title：Scientific reports

authors： Jiang Y,Liu W,Ming Q,Gao Y,Ma R,Zhang X,Situ W,Wang X,Yao S,Huang B

更新日期：2016-11-14 00:00:00

abstract：:Non-forest ecosystems (predominant in semi-arid and arid regions) contribute significantly to the increasing trend and interannual variation of land carbon uptake over the last three decades, yet the mechanisms are poorly understood. By analysing the flux measurements from 23 ecosystems in Australia, we found the the ...

journal_title：Scientific reports

authors： Li L,Wang YP,Beringer J,Shi H,Cleverly J,Cheng L,Eamus D,Huete A,Hutley L,Lu X,Piao S,Zhang L,Zhang Y,Yu Q

更新日期：2017-09-15 00:00:00

abstract：:Silver nanoparticles (AgNPs) have been extensively used and are considered as an emerging contaminant in the ocean. The environmental contamination of AgNPs is expected to increase greatly over time, and cetaceans, as the top ocean predators, will suffer the negative impacts of AgNPs. In the present study, we investig...

journal_title：Scientific reports

authors： Li WT,Chang HW,Yang WC,Lo C,Wang LY,Pang VF,Chen MH,Jeng CR

更新日期：2018-04-04 00:00:00

abstract：:α-synuclein (aS) is a natively unfolded pre-synaptic protein found in all Parkinson's disease patients as the major component of fibrillar plaques. Metal ions, and especially Cu(II), have been demonstrated to accelerate aggregation of aS into fibrillar plaques, the precursors to Lewy bodies. In this work, copper bindi...

journal_title：Scientific reports

authors： Rose F,Hodak M,Bernholc J

更新日期：2011-01-01 00:00:00

abstract：:Although the search for quantitative trait loci for behaviour remains a considerable challenge, the complicated genetic architecture of quantitative traits is beginning to be understood. The current project utilised heterogeneous stock (HS) male mice (n = 580) to investigate the genetic basis for brain weights, activi...

journal_title：Scientific reports

authors： Janecka M,Marzi SJ,Parsons MJ,Liu L,Paya-Cano JL,Smith RG,Fernandes C,Schalkwyk LC

更新日期：2017-02-01 00:00:00

abstract：:Within the framework of precision agriculture, the determination of various soil properties is moving into focus, especially the demand for sensors suitable for in-situ measurements. Energy-dispersive X-ray fluorescence (EDXRF) can be a powerful tool for this purpose. In this study a huge diverse soil set (n = 598) fr...

journal_title：Scientific reports

authors： Büchele D,Chao M,Ostermann M,Leenen M,Bald I

更新日期：2019-11-26 00:00:00