Osteostimulatory effect of biocomposite scaffold containing phytomolecule diosmin by Integrin/FAK/ERK signaling pathway in mouse mesenchymal stem cells.

abstract：:The influenza virus neuraminidase (NA) is essential for the virus life cycle. The rise of resistance mutations against current antiviral therapies has increased the need for the development of novel inhibitors. Recent efforts have targeted a cavity adjacent to the catalytic site (the 150-cavity) in addition to the pri...

journal_title：Scientific reports

authors： Kerry PS,Mohan S,Russell RJ,Bance N,Niikura M,Pinto BM

更新日期：2013-10-16 00:00:00

abstract：:Although low socioeconomic status (SES) is related to poor glycemic control, the underlying mechanisms remain unclear. We examined potentially modifiable factors involved in the association between low SES and poor glycemic control using data from the baseline survey of a multicenter, prospective cohort study. Five hu...

journal_title：Scientific reports

authors： Rahman M,Nakamura K,Hasan SMM,Seino K,Mostofa G

更新日期：2020-04-21 00:00:00

abstract：:The D40 gene encodes a kinetochore protein that plays an essential role in kinetochore formation during mitosis. Short inhibitory RNA against D40, D40 siRNA, has been shown to deplete the D40 protein in the human cancer cell line HeLa, which harbors wild-type p53, and this activity was followed by the significant inhi...

journal_title：Scientific reports

authors： Urata YN,Takeshita F,Tanaka H,Ochiya T,Takimoto M

更新日期：2015-09-08 00:00:00

abstract：:Studies have proven that IL-2 and IL-15 showed contrasting roles during CIK cells preparation. By employing microarray, we analyzed miRNA expression profiles of PBMC, CIKIL-2 and CIKIL-15. Advanced bioinformatic analyses were performed to explore the key miRNAs which may regulate cell proliferation and anti-tumor acti...

journal_title：Scientific reports

authors： Wang W,Li R,Meng M,Wei C,Xie Y,Zhang Y,Jiang L,Dong R,Wang C,Zhong Y,Yang F,Tang W,Jin X,Liu B,Hou Z

更新日期：2015-03-31 00:00:00

abstract：:Covalent functionalisation of graphene is a continuously progressing field of research. The optical properties of such derivatives attract particular attention. In virtually all optical responses, however, an enhancement in peak intensity with increase of sp3 carbon content, and a vanishing of the peak position shift ...

journal_title：Scientific reports

authors： Vecera P,Eigler S,Koleśnik-Gray M,Krstić V,Vierck A,Maultzsch J,Schäfer RA,Hauke F,Hirsch A

更新日期：2017-03-27 00:00:00

abstract：:Epstein Barr Virus (EBV) is a human herpesvirus, and has been reported to be associated with nasopharyngeal carcinoma, gastric carcinoma, Burkitt's lymphoma and Hodgkin's lymphoma. In most of the associated tumors, the virus remains in a latently infected state. During latency, EBV expresses Latent Membrane Protein 2A...

journal_title：Scientific reports

authors： Singh S,Banerjee S

更新日期：2020-03-25 00:00:00

abstract：:Prostate cancer is a common malignancy in men worldwide and it is known that oxidative stress is a risk factor for cancer development. A common functional haptoglobin (Hp) polymorphism, originating from a duplication of a gene segment spanning over two exons, results in three distinct phenotypes with different anti-ox...

journal_title：Scientific reports

authors： Kaiser M,Thurner EM,Mangge H,Herrmann M,Semeraro MD,Renner W,Langsenlehner T

更新日期：2020-08-04 00:00:00

abstract：:The push for a semiconductor-based quantum information technology has renewed interest in the spin states and optical transitions of shallow donors in silicon, including the donor bound exciton transitions in the near-infrared and the Rydberg, or hydrogenic, transitions in the mid-infrared. The deepest group V donor i...

journal_title：Scientific reports

authors： Saeedi K,Szech M,Dluhy P,Salvail JZ,Morse KJ,Riemann H,Abrosimov NV,Nötzel N,Litvinenko KL,Murdin BN,Thewalt ML

更新日期：2015-05-20 00:00:00

abstract：:The cysteine-rich PLAC8 domain of unknown function occurs in proteins found in most Eukaryotes. PLAC8-proteins play important yet diverse roles in different organisms, such as control of cell proliferation in animals and plants or heavy metal resistance in plants and fungi. Mammalian Onzin can be either pro-proliferat...

journal_title：Scientific reports

authors： Daghino S,Di Vietro L,Petiti L,Martino E,Dallabona C,Lodi T,Perotto S

更新日期：2019-04-29 00:00:00

abstract：:One current concept suggests that unchecked proliferation of clonally selected precursors of endothelial cells (ECs) contribute to severe pulmonary arterial hypertension (PAH). We hypothesized that clonally selected ECs expressing the progenitor marker CD117 promote severe occlusive pulmonary hypertension (PH). The re...

journal_title：Scientific reports

authors： Bhagwani AR,Farkas D,Harmon B,Authelet KJ,Cool CD,Kolb M,Goncharova E,Yoder MC,Clauss M,Freishtat R,Farkas L

更新日期：2020-01-24 00:00:00

abstract：:By eliminating the spherical aberrations of microsphere we derived a simple but useful formula on the focusing of dielectric microsphere. On basis of this formula, not only can researchers determine the parameters of an optical microsphere system with super-resolution, but they can also perform parameter transformatio...

journal_title：Scientific reports

authors： Xia T,Guo H,Hu J,Zhuang S

更新日期：2017-07-18 00:00:00

abstract：:Pharmacological activities of some natural products diminish and even disappear after purification. In this study, we explored the mechanisms underlying the decrease of acute oral toxicity of Coptidis Rhizoma extract after purification. The water solubility, in vitro absorption, and plasma exposure of berberine (the m...

journal_title：Scientific reports

authors： Ma BL,Yin C,Zhang BK,Dai Y,Jia YQ,Yang Y,Li Q,Shi R,Wang TM,Wu JS,Li YY,Lin G,Ma YM

更新日期：2016-01-29 00:00:00

abstract：:A tunable high-order sideband spectra generation scheme is presented by using a photonic molecule optomechanical system coupled to a waveguide beyond the perturbation regime. The system is coherently driven by a two-tone laser consisting of a continuous-wave control field and a pulsed driving field which propagates th...

journal_title：Scientific reports

authors： Cao C,Mi SC,Gao YP,He LY,Yang D,Wang TJ,Zhang R,Wang C

更新日期：2016-03-10 00:00:00

abstract：:Resistin, an adipokine involved in insulin resistance (IR) and diabetes, has recently been reported to play a role in cardiovascular events. However, its effect on blood pressure (BP) and the underlying mechanisms remain unclear. In the present study, we showed that resistin induces hypertension and IR in wild type (W...

journal_title：Scientific reports

authors： Jiang Y,Lu L,Hu Y,Li Q,An C,Yu X,Shu L,Chen A,Niu C,Zhou L,Yang Z

更新日期：2016-02-26 00:00:00

abstract：:The regulatory transcriptional factor PATZ1 is constantly downregulated in human thyroid cancer where it acts as a tumour suppressor by targeting p53-dependent genes involved in Epithelial-Mesenchymal Transition and cell migration. The aim of the present work was to elucidate the upstream signalling mechanisms regulat...

journal_title：Scientific reports

authors： Vitiello M,Valentino T,De Menna M,Crescenzi E,Francesca P,Rea D,Arra C,Fusco A,De Vita G,Cerchia L,Fedele M

更新日期：2016-04-29 00:00:00

abstract：:A low-cost compact planar leaky-wave antenna (LWA) is proposed offering directive broadside radiation over a significantly wide bandwidth. The design is based on an annular metallic strip grating (MSG) configuration, placed on top of a dual-layer grounded dielectric substrate. This defines a new two-layer parallel-pla...

journal_title：Scientific reports

authors： Comite D,Podilchak SK,Baccarelli P,Burghignoli P,Galli A,Freundorfer AP,Antar YMM

更新日期：2018-12-10 00:00:00

abstract：:This study aimed to determine the clinicopathological features of the subtypes of ampullary carcinoma (AC) to explore the indications for endoscopic papillectomy (EP) in early AC. Fifty-seven patients with AC who underwent curative resection were retrospectively reviewed. The 0/IA stages were significantly more common...

journal_title：Scientific reports

authors： Yamamoto K,Itoi T,Nagata N,Sofuni A,Tsuchiya T,Ishii K,Tanaka R,Tonozuka R,Honjo M,Mukai S,Asai Y,Matsunami Y,Yamaguchi H,Matsubayashi J,Joyama E,Nagakawa Y

更新日期：2021-01-12 00:00:00

abstract：:Biomass waste treatment and detrimental dye adsorption are two of the crucial environmental issues nowadays. In this study, we investigate to simultaneously resolve the aforementioned issues by synthesizing chitosan sponges as adsorbents toward rose bengal (RB) dye adsorption. Through a temperature-controlled freeze-c...

journal_title：Scientific reports

authors： Wang M,Ma Y,Sun Y,Hong SY,Lee SK,Yoon B,Chen L,Ci L,Nam JD,Chen X,Suhr J

更新日期：2017-12-22 00:00:00

abstract：:Here, we assessed the sulfated derivative of the microbial polysaccharide gellan gum and derivatives of λ and κ-carrageenans for their ability to inhibit Plasmodium falciparum 3D7 and Dd2 growth and invasion of red blood cells in vitro. Growth inhibition was assessed by means of flow cytometry after a 96-h exposure to...

journal_title：Scientific reports

authors： Recuenco FC,Kobayashi K,Ishiwa A,Enomoto-Rogers Y,Fundador NG,Sugi T,Takemae H,Iwanaga T,Murakoshi F,Gong H,Inomata A,Horimoto T,Iwata T,Kato K

更新日期：2014-04-17 00:00:00

abstract：:Mucociliary clearance is a biomechanical mechanism of airway protection. It consists of the active transport along the bronchial tree of the mucus, a fluid propelled by the coordinated beating of a myriad of cilia on the epithelial surface of the respiratory tract. The physics of mucus transport is poorly understood b...

journal_title：Scientific reports

authors： Khelloufi MK,Loiseau E,Jaeger M,Molinari N,Chanez P,Gras D,Viallat A

更新日期：2018-02-05 00:00:00

abstract：:Spin-orbit coupling (SOC) plays an essential role in many exotic and interesting phenomena in condensed matter physics. In neutral-atom-based quantum simulations, synthetic SOC constitutes a key enabling element. The strength of SOC realized so far is limited by various reasons or constraints. This work reports tunabl...

journal_title：Scientific reports

authors： Wu LN,Luo XY,Xu ZF,Ueda M,Wang R,You L

更新日期：2017-04-27 00:00:00

abstract：:Essential oils are volatile compounds commonly used by several industries, easily degradable, which restrains their applications. Therefore, we developed and validated a methodology for producing microcapsules loaded with orange essential oil, using a spray-drying process. The experimental design results showed that t...

journal_title：Scientific reports

authors： Aguiar MCS,das Graças Fernandes da Silva MF,Fernandes JB,Forim MR

更新日期：2020-07-16 00:00:00

abstract：:The aim was to investigate the ability of self-assembling Peptide P11-4 Matrix (SAPM) to remineralize artificial initial caries lesions compared to the use of fluoride varnish. Volunteers were recruited for this randomised, cross-over in situ trial. Bovine specimens, half including orthodontic brackets, were recessed ...

journal_title：Scientific reports

authors： Jablonski-Momeni A,Korbmacher-Steiner H,Heinzel-Gutenbrunner M,Jablonski B,Jaquet W,Bottenberg P

更新日期：2019-01-22 00:00:00

abstract：:Long noncoding RNAs (lncRNAs) represent a vast unexplored genetic space that may hold missing drivers of tumourigenesis, but few such "driver lncRNAs" are known. Until now, they have been discovered through changes in expression, leading to problems in distinguishing between causative roles and passenger effects. We h...

journal_title：Scientific reports

authors： Lanzós A,Carlevaro-Fita J,Mularoni L,Reverter F,Palumbo E,Guigó R,Johnson R

更新日期：2017-01-27 00:00:00

abstract：:To date, the cell and molecular mechanisms regulating tendon healing are poorly understood. Here, we establish a novel model of tendon regeneration using neonatal mice and show that neonates heal via formation of a 'neo-tendon' that differentiates along the tendon specific lineage with functional restoration of gait a...

journal_title：Scientific reports

authors： Howell K,Chien C,Bell R,Laudier D,Tufa SF,Keene DR,Andarawis-Puri N,Huang AH

更新日期：2017-03-23 00:00:00

abstract：:Neuro-Behçet's disease (NBD) is subcategorized into parenchymal-NBD (P-NBD) and non-parenchymal-NBD types. Recently, P-NBD has been further subdivided into acute P-NBD (A-P-NBD) and chronic progressive P-NBD (CP-P-NBD). Although an increasing number of studies have reported the various clinical features of A-P-NBD and...

journal_title：Scientific reports

authors： Ishido M,Horita N,Takeuchi M,Shibuya E,Yamane T,Kawagoe T,Ishido T,Minegishi K,Yoshimi R,Kirino Y,Hirohata S,Ishigatsubo Y,Takeno M,Kaneko T,Mizuki N

更新日期：2017-08-31 00:00:00

abstract：:The expansion of agriculture is shrinking pristine forest areas worldwide, jeopardizing the persistence of their wild inhabitants. The Udzungwa red colobus monkey (Procolobus gordonorum) is among the most threatened primate species in Africa. Primarily arboreal and highly sensitive to hunting and habitat destruction, ...

journal_title：Scientific reports

authors： Barelli C,Albanese D,Donati C,Pindo M,Dallago C,Rovero F,Cavalieri D,Tuohy KM,Hauffe HC,De Filippo C

更新日期：2015-10-07 00:00:00

abstract：:This was a nine-year retrospective cohort study to investigate obstetric and perinatal outcomes in a cohort of adolescent girls with twin pregnancies from a major Australian tertiary centre in Brisbane, Australia. The adolescent cohort was aged <19 years and the control group was aged 20-24 years. The total study coho...

journal_title：Scientific reports

authors： Robson D,Daniels S,Flatley C,Kumar S

更新日期：2018-12-24 00:00:00

abstract：:Mitochondrial dysfunction is implicated in many human diseases and occurs in normal aging. Mitochondrial health is maintained through organelle biogenesis and repair or turnover of existing mitochondria. Mitochondrial turnover is principally mediated by mitophagy, the trafficking of damaged mitochondria to lysosomes v...

journal_title：Scientific reports

authors： Sargsyan A,Cai J,Fandino LB,Labasky ME,Forostyan T,Colosimo LK,Thompson SJ,Graham TE

更新日期：2015-07-28 00:00:00

abstract：:Real-time Precise Point Positioning (PPP) technique is being widely applied for providing precise positioning services with the significant improvement on satellite precise products accuracy. With the rapid development of the multi-constellation Global Navigation Satellite Systems (multi-GNSS), currently, about 80 nav...

journal_title：Scientific reports

authors： Gao Z,Shen W,Zhang H,Niu X,Ge M

更新日期：2016-07-29 00:00:00