Abstract:
PURPOSE:The purpose of the study was to evaluate the tolerability and functionality of a wireless ocular telemetry sensor in African American patients with glaucoma. MATERIALS AND METHODS:In this prospective, observational cohort study, 20 African American patients with primary open angle glaucoma (POAG) were evaluated at the University of Colorado Eye Center. Before lens placement, patients recorded ocular comfort and underwent a baseline eye exam. Following the exam, patients were fitted with a SENSIMED Triggerfish contact lens sensor and data recording device. Patients were sent home and instructed to record their activities in a journal and return in 24 hours. Repeat exams were performed at various time points in clinic before and after lens removal. RESULTS:All 20 patients retained the lens for the 24-hour study period. The patient reported comfort was excellent, with a nadir of mean recorded comfort of 7.05/10. Significant clinical changes were noted in lid/conjunctival erythema, BCVA, refraction, and pachymetry over the course of lens wear. The majority of these changes were improved or resolved by 1 hour after lens removal. Voltage output was significantly greater nocturnally than diurnally (184.79 mV and 71.48 mV, respectively; P<0.0001). There was no significant change in signal variability or slope over the entire duration of the sleep/wake period based on sleep. CONCLUSIONS:The wireless ocular sensor is well tolerated over a 24-hour period in African American patients with POAG despite transient changes in visual acuity and conjunctival erythema. Clinically usable 24-hour profiles were generated for all patients, with voltage output increasing significantly during periods of sleep.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Marando CM,Mansouri K,Kahook MY,Seibold LKdoi
10.1097/IJG.0000000000001141subject
Has Abstractpub_date
2019-02-01 00:00:00pages
119-124issue
2eissn
1057-0829issn
1536-481Xpii
00061198-201902000-00005journal_volume
28pub_type
杂志文章abstract::Our purpose is to document the first case of unilateral mild corneal ectasia developed in an apparently nonpredisposed cornea after topical latanoprost treatment, and its regression after treatment withdrawal. We describe a 44-year-old man with visual impairment in his left eye (OS) and a past medical history of myopi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001660
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:To examine clinical outcomes following an initial trabeculectomy with mitomycin-C for secondary glaucoma associated with uveitis in Behçet disease (BD) patients. DESIGN:Retrospective interventional case series. PATIENTS AND METHODS:Twenty-two eyes in 18 patients with uveitic glaucoma (UG) associated with Behç...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000665
更新日期:2017-07-01 00:00:00
abstract:PRECIS:Chinese Glaucoma Study Consortium (CGSC) as the first nationwide glaucoma registry in China, we describe its design, rationale, the geographic distribution of the hospitals, and baseline patient characteristics. AIM:As a leading cause of blindness in China, glaucoma affects 2% to 4% of adults over the age of 40...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001378
更新日期:2019-11-01 00:00:00
abstract:PURPOSE:To assess and compare the impact of medical and surgical glaucoma treatments on patients' health-related Quality of Life (QoL). MATERIALS AND METHODS:We used the 25-question version of the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) for this cross-sectional study. Patients were divided...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31824ceb8b
更新日期:2013-06-01 00:00:00
abstract:PURPOSE:We assessed vision-related quality of life (VR-QOL) in glaucoma patients and examined the relationship between VR-QOL and indices of visual function and subjective symptoms. PATIENTS AND METHODS:Four hundred seventy-two glaucoma patients completed a questionnaire concerning VR-QOL and subjective symptoms of gl...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究
doi:10.1097/IJG.0000000000000221
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy. METHODS:We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence t...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000326
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To evaluate the outcome of modified deep sclerectomy [D-lectomy mitomycin C (MMC)] for medically refractory glaucoma patients. METHODS:In a retrospective comparative study, the surgical outcome in 1 eye each of 31 patients who underwent D-lectomy MMC was compared with that of 91 eyes of 91 patients who underwe...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181752cc8
更新日期:2009-02-01 00:00:00
abstract:PURPOSE:To describe the appearance of a defect in the parapapillary region of a highly myopic eye. METHODS:During a routine ophthalmologic examination, in a 26-year-old man with a visual acuity of 0.80 and a refractive error of -10.25 D, a dehiscence in the parapapillary region was detected. A choroidal vessel appeare...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000438610.31653.48
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To determine the risk factors for hyphema after trabeculectomy with mitomycin C (MMC). PATIENTS AND METHODS:In total, 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto University Hospital, Japan, were retrospectively evaluated. Hy...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3182741c85
更新日期:2014-06-01 00:00:00
abstract::The pressure on glaucoma services is ever-growing, and policymakers seek robust cost-effectiveness arguments in their decisions around resource allocation. The benefits of glaucoma are in preventing or delaying a future loss of vision and associated quality of life, and this expectation is quantified using a metric ca...
journal_title:Journal of glaucoma
pub_type: 杂志文章,评审
doi:10.1097/IJG.0000000000001462
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:This study was conducted to evaluate the effect of long-term intraocular pressure reduction with timolol on the incidence of glaucomatous visual field defects and optic nerve cupping in individuals with ocular hypertension and to compare this incidence with that of a similar group on no treatment. ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:The purpose of this article was to report the efficacy of intravitreal bevacizumab to resolve secondary angle-closure glaucoma caused by biliary tract carcinoma metastasis to the iris. MATERIALS AND METHODS:A 52-year-old white woman who was under systemic chemotherapy for biliary tract carcinoma presented with...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000959
更新日期:2018-06-01 00:00:00
abstract::Glaucoma is a progressive optic neuropathy that is the leading cause of irreversible blindness in the world. Although methods to lower intraocular pressure are the mainstay of glaucoma therapy, there are currently no available treatment modalities targeted at neuroprotection. Erythropoietin is a hematopoietic cytokine...
journal_title:Journal of glaucoma
pub_type: 杂志文章,评审
doi:10.1097/IJG.0b013e318156a556
更新日期:2007-09-01 00:00:00
abstract:PURPOSE:The authors quantitatively evaluate the kinetics of fluid transfer from microsurgical sponges in a laboratory model to understand the kinetics of mitomycin C (MMC) delivery. METHODS:The amount of fluid transferred from soaked methylcellulose (Weck-cel, Weck Inc., Durham, NC, U.S.A.) sponges to small pieces of ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1998-02-01 00:00:00
abstract:PURPOSE:Multiuse of the G-probe transscleral cyclophotocoagulation (TSCPC) device can lead to contamination. We evaluated the mechanical stability and clinical efficacy of a disposable sterile barrier for the G-probe footplate. METHODS:We measured diode laser output with and without the G-probe barrier both before and...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181e08109
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:To compare the rates of retinal nerve fiber layer (RNFL) thickness loss using optical coherence tomography (OCT) in progressing versus nonprogressing eyes using 4 methods to define functional progression. METHODS:Normal and glaucomatous eyes with ≥3 years of follow up were prospectively enrolled. Standard auto...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3182071cc7
更新日期:2012-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the risk of developing glaucoma in patients taking systemic fluoroquinolones. METHODS:A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed wi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31829463c1
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:To evaluate the effects of flunarizine, a nonselective calcium channel blocker, on intraocular pressure (IOP) in monkeys with laser-induced unilateral glaucoma and on aqueous humor dynamics in normal monkeys. METHODS:The IOP was measured before and hourly for 6 hours after single-dose administration of 0.5%, 1...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e318133a845
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To determine if there is a difference in response to metyrapone, which blocks the conversion of 11-deoxycortisol to cortisol in the adrenal gland between normals and ocular hypertensives (OH) plus primary open-angle glaucomas (POAG) without pigmented angles. METHODS:Intravenous metyrapone was given to 20 norma...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000185613.56168.9d
更新日期:2005-12-01 00:00:00
abstract:PURPOSE:To evaluate the intraocular pressure (IOP) lowering effect of the XEN140 microfistula gel stent implant for the surgical treatment of open-angle glaucoma. PATIENTS AND METHODS:Forty-nine eyes of 49 patients with an IOP>18 mm Hg and ≤35 mm Hg were studied in a prospective nonrandomized multicenter cohort trial ...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/IJG.0000000000000352
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To report a case of an angle-closure glaucoma in a patient with Miller Fisher syndrome (MFS) without pupillary dysfunction. METHODS:We present a case report of a 75-year-old male presenting with total ophthalmoplegia, complete bilateral ptosis, and gait disturbance. He was diagnosed with MFS without pupillary ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000191
更新日期:2015-02-01 00:00:00
abstract:PURPOSE:To report a simple technique for removal of malpositioned Ex-PRESS miniature glaucoma filtration device. PATIENT AND METHODS:A patient who underwent removal of a malpositioned Ex-PRESS shunt from the right eye with wound revision. RESULTS:Description of step-by-step technique for removal of the Ex-PRESS shunt...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31827b1540
更新日期:2014-09-01 00:00:00
abstract:PURPOSE:To evaluate strength of associations between optical coherence tomography (OCT)-angiography vessel density (VD) measurements in the macula and peripapillary region of the optic nerve head (ONH) with standard structural OCT thickness measures. MATERIALS AND METHODS:This cross-sectional study included 333 eyes o...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000862
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:This meta-analysis aims to comprehensively evaluate the association between total homocysteine (tHcy) levels, serum folic acid, vitamin B12, vitamin B6 levels, methylenetetrahydrofolate reductase (MTHFR) C677T genotype, and risk of normal-tension glaucoma (NTG). MATERIALS AND METHODS:A systematic search of ...
journal_title:Journal of glaucoma
pub_type: 杂志文章,meta分析
doi:10.1097/IJG.0000000000000269
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. MATERIALS AND METHODS:A novel AS-OCT grading system based on bleb size and internal reflectivity was devel...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000636
更新日期:2017-05-01 00:00:00
abstract:PURPOSE:To examine intra- and interrater agreement when analyzing cumulative defect curves. Cumulative defect (Bebié) curves provide a graphical representation of the visual field and allow a subjective classification of diffuse and localized loss. METHODS:We used 75 Humphrey 30-2 visual field tests, randomly chosen f...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract:PRECIS:Rabbit model studies suggested better morphology blebs with equal intraocular pressure (IOP) efficacy as a standard mitomycin C (MMC) trabeculectomy using a novel slow-release drug delivery antifibrotic system delivering small quantities of MMC and 5-fluorouracil (5-FU). PURPOSE:To evaluate 2 different concentr...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001215
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To evaluate the relationship between glaucomatous structural damage assessed by the Cirrus Spectral Domain OCT (SDOCT) and functional loss as measured by standard automated perimetry (SAP). METHODS:Four hundred twenty-two eyes (78 healthy, 210 suspects, 134 glaucomatous) of 250 patients were recruited from the...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31822af27a
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To evaluate aqueous levels of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in patients with branch retinal vein occlusion (BRVO) with and without normal tension glaucoma (NTG), and to assess the therapeutic efficacy of intravitreal bevacizumab (IVB) in these patients. METHODS:Sixteen eyes ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3182312047
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:We measured changes in the corneal morphology and intraocular pressure (IOP) before and after the use of contact lens sensor (CLS). Then, we investigated whether the ocular dimensional change affected the measured IOP value with CLS. MATERIAL AND METHODS:In this prospective study, we examined 112 eyes of glauc...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001318
更新日期:2019-09-01 00:00:00