Abstract:
PURPOSE:To evaluate strength of associations between optical coherence tomography (OCT)-angiography vessel density (VD) measurements in the macula and peripapillary region of the optic nerve head (ONH) with standard structural OCT thickness measures. MATERIALS AND METHODS:This cross-sectional study included 333 eyes of 219 primary open-angle glaucoma patients, 41 glaucoma suspects, and 73 healthy participants from the Diagnostic Innovations in Glaucoma Study (DIGS) with good quality OCT angiography images. The strength of associations between microvasculature measures in the ONH retinal nerve fiber layer (RNFL) and superficial macula layer was assessed using linear regression models. Associations between ONH and macula VD, and circumpapillary (cp) RNFL thickness and macular ganglion cell complex (mGCC) measures were also evaluated. RESULTS:The strength (r) of associations among VD and thickness measures of ONH and macula ranged from 14.1% to 69.4%; all were statistically significant (P<0.001). The association between ONH and macula whole-image VD (r=41.0%) was significantly weaker than the relationship between mGCC and cpRNFL thickness (r=69.4%, P<0.001). Although both cpRNFL and mGCC thicknesses tended to be more strongly associated with ONH VD (r=39.2% and 26.7%, respectively) than macula VD (r=27.5% and 17.7%, respectively), differences did not reach statistical significance (P=0.050 and P=0.113, respectively). CONCLUSIONS:The strength of the association of VD with cpRNFL and mGCC thicknesses varies by retinal layer. The weaker association of macula VD compared with ONH VD with tissue thickness may be due to differences in micorovasculature between the macula and ONH.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Manalastas PIC,Zangwill LM,Daga FB,Christopher MA,Saunders LJ,Shoji T,Akagi T,Penteado RC,Yarmohammadi A,Suh MH,Medeiros FA,Weinreb RNdoi
10.1097/IJG.0000000000000862subject
Has Abstractpub_date
2018-03-01 00:00:00pages
227-232issue
3eissn
1057-0829issn
1536-481Xjournal_volume
27pub_type
杂志文章abstract:OBJECTIVE:To describe reoperations in the operating room for complications encountered within 90 days after glaucoma surgery at a single institution over a 2-year period. DESIGN:Retrospective case series. SUBJECTS:Adult patients who have undergone glaucoma surgery including a tube shunt, trabeculectomy with mitomycin...
journal_title:Journal of glaucoma
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:Journal of glaucoma
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doi:10.1097/IJG.0b013e31817d235c
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更新日期:2019-04-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1999-04-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000212210.33265.24
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:The authors describe the first case of delayed antimetabolite-related corneal epithelial toxicity after trabeculectomy and its successful treatment with limbal stem cell transplantation. METHODS:A 73-year-old woman underwent trabeculectomy with intraoperative mitomycin C. After surgery she received six 5-mg in...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract:PURPOSE:This study investigated the effects of posterior sub-Tenon capsule (PST) injection of triamcinolone acetonide (TA) on intraocular pressure (IOP) in the human eye. METHODS:The study included 115 patients who received PST injections of 40-mg TA to treat macular edema with diabetic retinopathy (n=57), branch reti...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31802d696f
更新日期:2007-03-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001538
更新日期:2020-07-01 00:00:00
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更新日期:2016-06-01 00:00:00
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更新日期:2019-09-01 00:00:00
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journal_title:Journal of glaucoma
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abstract::PRéCIS:: Four parameters of the noninvasive, portable RETeval electroretinogram (ERG) system were found to correlate with visual field mean deviation and optical coherence tomography (OCT) thickness parameters, and may therefore be suitable for glaucoma detection. PURPOSE:To investigate the RETeval full-field ERG par...
journal_title:Journal of glaucoma
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doi:10.1097/IJG.0000000000001509
更新日期:2020-07-01 00:00:00
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journal_title:Journal of glaucoma
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更新日期:2014-09-01 00:00:00
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journal_title:Journal of glaucoma
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doi:10.1097/IJG.0b013e318287aba0
更新日期:2014-12-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00061198-200402000-00006
更新日期:2004-02-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001183
更新日期:2019-03-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31815768b3
更新日期:2008-04-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000877
更新日期:2018-04-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
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更新日期:2014-10-01 00:00:00
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更新日期:2007-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e318265bc0b
更新日期:2014-02-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e318225472a
更新日期:2013-01-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000212289.00917.a8
更新日期:2006-12-01 00:00:00
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journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2015-06-01 00:00:00