Ciliary body melanocytoma with anterior segment pigment dispersion and elevated intraocular pressure.

Abstract:

PURPOSE:To discuss a case in which melanocytoma of the ciliary body presented with widespread pigment dispersion and elevated intraocular pressure (IOP). METHODS:A 64-year old woman presented with increased IOP and persistent anterior segment inflammation in her right eye. She had undergone a trabeculectomy for uncontrolled IOP before presentation. Slit-lamp examination, gonioscopy, and ultrasound biomicroscopy revealed a ciliary body mass with extension into the subconjunctiva in addition to widespread pigmentary dispersion in the anterior segment. Enucleation of the right eye was performed for histopathologic evaluation, as a diagnosis of ciliary body melanoma was made on clinical examination. RESULTS:Histopathologic findings were diagnostic of a melanocytoma of the ciliary body with necrosis and focal malignant transformation with extension of melanocytoma cells and melanophages into the subconjunctival space, trabecular meshwork, and anterior chamber angle. CONCLUSION:Melanocytoma of the ciliary body is a rare intraocular tumor that may present with pigment dispersion and secondary elevated IOP. Careful examination of the anterior segment is imperative in such cases.

journal_name

J Glaucoma

journal_title

Journal of glaucoma

authors

Bhorade AM,Edward DP,Goldstein DA

keywords:

subject

Has Abstract

pub_date

1999-04-01 00:00:00

pages

129-33

issue

2

eissn

1057-0829

issn

1536-481X

journal_volume

8

pub_type

杂志文章
  • Hypotony Keratopathy Following Trabeculectomy.

    abstract:PRECIS:Hypotony keratopathy is a potential complication of hypotony following trabeculectomy and successful treatment depends on increasing intraocular pressure (IOP). PURPOSE:To evaluate corneal decompensation in patients following trabeculectomy with adjuvant mitomycin C (MMC). We propose "hypotony keratopathy" as a...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001425

    authors: Camp AS,Weinreb RN

    更新日期:2020-02-01 00:00:00

  • Kinetics of fluid delivery from methylcellulose sponges.

    abstract:PURPOSE:The authors quantitatively evaluate the kinetics of fluid transfer from microsurgical sponges in a laboratory model to understand the kinetics of mitomycin C (MMC) delivery. METHODS:The amount of fluid transferred from soaked methylcellulose (Weck-cel, Weck Inc., Durham, NC, U.S.A.) sponges to small pieces of ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:

    authors: Brooks SE,Laird ML,Marcus DM,Johnson MH,Ramage JI,Green K

    更新日期:1998-02-01 00:00:00

  • "Bleb window"-pexy for the management of symptomatic, oversized blebs.

    abstract:PURPOSE:To describe a simple method and outcomes of remodeling dysesthetic, oversized filtering blebs. PATIENTS AND METHODS:Retrospective chart review of the initial consecutive patients who had undergone "bleb window"-pexy (BWP) over a 1-year period. Patients with symptomatic, oversized, and dysmorphic blebs that did...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181815a06

    authors: Tabet R,Feldman RM,Bell NP,Lee DA

    更新日期:2009-09-01 00:00:00

  • Intereye Symmetry of 24-Hour Intraocular Pressure-related Patterns in Untreated Glaucoma Patients Using a Contact Lens Sensor.

    abstract:PURPOSE:Scarce data are available on the symmetry of 24-hour intraocular pressure (IOP) variations between fellow eyes of glaucoma patients, and such evidence could have profound consequences on the interpretation of monocular therapeutic trials. The objective is to evaluate the intereye correlation of continuously mea...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001563

    authors: Mansouri K,Gillmann K

    更新日期:2020-08-01 00:00:00

  • Xen Gel Stent to Resolve Late Hypotony After Glaucoma Drainage Implant Surgery: A Novel Technique.

    abstract:PURPOSE:To describe a new surgical method for treating late profound hypotony in 2 patients with glaucoma drainage implant (GDI). PATIENTS AND METHODS:Two patients, an 85-year-old woman and a 44-year-old woman, presented with choroidal effusions secondary related to chronic hypotony after GDI surgery. A novel techniqu...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001022

    authors: Välimäki J

    更新日期:2018-10-01 00:00:00

  • Aqueous vascular endothelial growth factor and endothelin-1 levels in branch retinal vein occlusion associated with normal tension glaucoma.

    abstract:PURPOSE:To evaluate aqueous levels of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in patients with branch retinal vein occlusion (BRVO) with and without normal tension glaucoma (NTG), and to assess the therapeutic efficacy of intravitreal bevacizumab (IVB) in these patients. METHODS:Sixteen eyes ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3182312047

    authors: Sin BH,Song BJ,Park SP

    更新日期:2013-02-01 00:00:00

  • Trabeculectomy Following Failed Ab Interno Gelatin Microstent: Case Series.

    abstract:PURPOSE:The purpose of this study is to describe the outcomes of mitomycin C (MMC)-augmented trabeculectomy performed following a failed MMC-augmented XEN-45 implantation. DESIGN:Retrospective case series. METHODS:All consecutive cases of MMC-augmented trabeculectomy performed after MMC-augmented XEN-45 in the Glauco...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001000

    authors: Gizzi C,Mohamed-Noriega J,Elkarmouty A,Scott A

    更新日期:2018-10-01 00:00:00

  • Effects of Nonporous Silica Nanoparticles on Human Trabecular Meshwork Cells.

    abstract:PRECIS:Silica nanoparticles (SiNPs), which are potential drug carriers for glaucoma treatment, may induce mild dose-dependent cytotoxicity but not so severe as to compromise a mammalian target of rapamycin (mTOR) pathway in immortalized trabecular meshwork (TM) cells. PURPOSE:Nanoparticle-based ophthalmic drug deliver...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001709

    authors: Kim M,Park JH,Jeong H,Hong J,Park CY

    更新日期:2021-02-01 00:00:00

  • Postural response of intraocular pressure and visual field damage in patients with untreated normal-tension glaucoma.

    abstract:PURPOSE:To evaluate whether postural changes of intraocular pressure (IOP) are associated with visual field damage by comparing both eyes of patients with previously untreated normal-tension glaucoma (NTG). PATIENTS AND METHODS:Forty eyes of 20 patients newly diagnosed as bilateral NTG were studied. IOP was measured i...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181a98f30

    authors: Kiuchi T,Motoyama Y,Oshika T

    更新日期:2010-03-01 00:00:00

  • Clinical Implications of In Vivo Lamina Cribrosa Imaging in Glaucoma.

    abstract::The lamina cribrosa (LC) is a multilayered, collagenous, sieve-like structure at the deep optic nerve head, and is presumed to be the primary site of axonal injury. According to biomechanical theory, intraocular pressure-induced posterior deformation of the LC causes blockage of axonal transport and alters the ocular ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,评审

    doi:10.1097/IJG.0000000000000728

    authors: Kim YW,Jeoung JW,Kim YK,Park KH

    更新日期:2017-09-01 00:00:00

  • Comparing the Performance of Compass Perimetry With Humphrey Field Analyzer in Eyes With Glaucoma.

    abstract:PURPOSE:To evaluate the reliability indices [fixation losses, false negative response rates (FN) and false positive response rates] and threshold sensitivities obtained from glaucoma patients with a Compass perimeter and to compare the same with the Humphrey field analyzer (HFA). METHODS:In a cross-sectional study, 97...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000609

    authors: Rao HL,Raveendran S,James V,Dasari S,Palakurthy M,Reddy HB,Pradhan ZS,Rao DA,Puttaiah NK,Devi S

    更新日期:2017-03-01 00:00:00

  • Outcomes of pars plana glaucoma drainage implant in Boston type 1 keratoprosthesis surgery.

    abstract:PURPOSE:Glaucoma drainage implantation in conjunction with Boston Type 1 Keratoprosthesis placement is a surgical option in controlling postoperative glaucoma. The purpose of this study is to report outcomes of combined pars plana vitrectomy and glaucoma drainage implantation with corneal patch graft in Boston Type 1 K...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31829e55f8

    authors: Huh ES,Aref AA,Vajaranant TS,de la Cruz J,Chau FY,Cortina MS

    更新日期:2014-01-01 00:00:00

  • Preliminary Report on a Novel Virtual Reality Perimeter Compared With Standard Automated Perimetry.

    abstract:PRECIS:The VisuALL head-mounted perimetry in normal subjects and glaucoma patients had a moderate to strong correlation with the Humphrey Field Analyzer (HFA). PURPOSE:Visual field testing has a vital role in diagnosing and managing glaucoma. The current clinical practice relies on large, table-based testing units. Th...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001670

    authors: Razeghinejad R,Gonzalez-Garcia A,Myers JS,Katz LJ

    更新日期:2021-01-01 00:00:00

  • Assessing the Methodological Quality of Glaucoma Clinical Practice Guidelines and Their Recommendations on Microinvasive Glaucoma Surgery: A Systematic Review.

    abstract:INTRODUCTION:Clinical practice guidelines (CPG) are regarded by many as critical communications providing guidance within specific medical fields. Over a decade ago, the first microinvasive glaucoma surgical (MIGS) procedures were introduced. Since then, a number of these novel intraocular pressure controlling surgical...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000820

    authors: Michaelov E,Armstrong JJ,Nguyen M,Instrum B,Lam T,Denstedt J,Hutnik CML

    更新日期:2018-02-01 00:00:00

  • The Cost and Economics of Endoscopic Cyclophotocoagulation in the United Kingdom: A Tertiary Center Experience.

    abstract:PRECIS:As the only microinvasive glaucoma surgery (MIGS) with a reusable component, the cost per procedure of endoscopic cyclophotocoagulation (ECP) diminishes with each successive use. We present a cost comparison of ECP with other MIGS devices, based on our clinical practice. PURPOSE:ECP delivers diode laser via a r...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001245

    authors: Ho H,Ho J,Rodrigues I,Syrimi M,Goyal S,Lim KS

    更新日期:2019-06-01 00:00:00

  • Characteristics of pseudoexfoliation in the Thessaloniki Eye Study.

    abstract:PURPOSE:To report on the prevalence of pseudoexfoliation (PEX) and its association with ophthalmic characteristics and systemic diseases in a well-defined population. METHODS:The Thessaloniki Eye study is a cross-sectional population-based study of chronic eye diseases in Thessaloniki, Greece. Participants with PEX we...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e3181d9d8bd

    authors: Anastasopoulos E,Topouzis F,Wilson MR,Harris A,Pappas T,Yu F,Koskosas A,Founti P,Coleman AL

    更新日期:2011-03-01 00:00:00

  • Scanning protocol choice affects optical coherence tomography (OCT-3) measurements.

    abstract:PURPOSE:To determine the optimal OCT-3 scanning protocol. METHODS:Normal subjects, ocular hypertensive, and open-angle glaucoma patients were enrolled. The "fast" RNFL scan protocol consists of 3 consecutive circular scans, each containing 256 A-scans obtained in a single 1.92 second session. The "regular" RNFL scan p...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/00061198-200404000-00010

    authors: Zafar S,Gurses-Ozden R,Makornwattana M,Vessani R,Liebmann JM,Tello C,Ritch R

    更新日期:2004-04-01 00:00:00

  • Acute angle-closure glaucoma in a patient with miller fisher syndrome without pupillary dysfunction.

    abstract:PURPOSE:To report a case of an angle-closure glaucoma in a patient with Miller Fisher syndrome (MFS) without pupillary dysfunction. METHODS:We present a case report of a 75-year-old male presenting with total ophthalmoplegia, complete bilateral ptosis, and gait disturbance. He was diagnosed with MFS without pupillary ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000191

    authors: Ryu WY,Kim JK,Jin SW,Shim DH

    更新日期:2015-02-01 00:00:00

  • Ethnicity and Deprivation are Associated With Blindness Among Adults With Primary Glaucoma in Nigeria: Results From the Nigeria National Blindness and Visual Impairment Survey.

    abstract:PURPOSE:We explored the risk factors for glaucoma blindness among adults aged 40 years and above with primary glaucoma in Nigeria. PARTICIPANTS AND METHODS:A total of 13,591 participants aged 40 years and above were examined in the Nigeria Blindness Survey; 682 (5.02%; 95 CI, 4.60%-5.47%) had glaucoma by ISGEO's crite...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000487

    authors: Kyari F,Wormald R,Murthy GV,Evans JR,Gilbert CE,Nigeria National Blindness and Visual Impairment Study Group.

    更新日期:2016-10-01 00:00:00

  • Possible association between long anterior lens zonules and plateau iris configuration.

    abstract:PURPOSE:To report plateau iris configuration (PIC) in subjects who have the long anterior zonule (LAZ) clinical trait. METHODS:Two elderly African American males who exhibited LAZ and had partial appositional angle closure persisting after laser iridotomy were imaged with high-resolution ultrasonography to examine for...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31815c3b04

    authors: Roberts DK,Ayyagari R,Moroi SE

    更新日期:2008-08-01 00:00:00

  • Effects of bunazosin hydrochloride on ciliary muscle constriction and matrix metalloproteinase activities.

    abstract:PURPOSE:To clarify the mechanism by which bunazosin hydrochloride (BZ), a selective alpha1-adrenoceptor antagonist, increases uveoscleral outflow. METHODS:The effects of BZ on matrix metalloproteinase (MMP) activities in cultured monkey ciliary muscle cells, and on phenylephrine hydrochloride-induced constriction in b...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/00061198-200408000-00009

    authors: Akaishi T,Takagi Y,Matsugi T,Ishida N,Hara H,Kashiwagi K

    更新日期:2004-08-01 00:00:00

  • Glycomics, extracellular matrix, and anti-glycan antibodies in exfoliation syndrome.

    abstract::Exfoliation syndrome (XFS) is considered to be a disease of extracellular matrix. Here we review key experimental evidence of aberrations in structure, expression, and function of glycoproteins, complex carbohydrates, and glycosaminoglycans found in extracellular matrix components forming exfoliation material in patie...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,评审

    doi:10.1097/IJG.0000000000000118

    authors: Huflejt ME,Preiss JS,Thomson JE,Gils IM,Vuskovic MI

    更新日期:2014-10-01 00:00:00

  • Incidence of glaucoma in patients with uveitis.

    abstract:PURPOSE:To evaluate the incidence of glaucoma and elevation of intraocular pressure (IOP) in patients with inflammatory eye disease. METHODS:Retrospective review of medical records of 391 consecutive patients with uveitis attending a uveitis clinic of an academic Department of Ophthalmology from January 1999 to August...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/01.ijg.0000146391.77618.d0

    authors: Neri P,Azuara-Blanco A,Forrester JV

    更新日期:2004-12-01 00:00:00

  • Imaging visual cortical structure and function in vivo.

    abstract::The recent advent of in vivo two-photon microscopy has allowed the repeat imaging of cortical structures at microscopic resolution within intact brains. Recent data obtained using this imaging technique shows that dendritic spines, the postsynaptic sites of the majority of excitatory synapses in the central nervous sy...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,评审

    doi:10.1097/IJG.0b013e3182934a30

    authors: Majewska AK

    更新日期:2013-06-01 00:00:00

  • The Chinese Glaucoma Study Consortium for Patients With Glaucoma: Design, Rationale and Baseline Patient Characteristics.

    abstract:PRECIS:Chinese Glaucoma Study Consortium (CGSC) as the first nationwide glaucoma registry in China, we describe its design, rationale, the geographic distribution of the hospitals, and baseline patient characteristics. AIM:As a leading cause of blindness in China, glaucoma affects 2% to 4% of adults over the age of 40...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000001378

    authors: Zhang H,Jia H,Duan X,Li L,Wang H,Wu J,Hu J,Cao K,Zhao A,Liang J,Song J,Qiao C,Wang N,Investigators for The Chinese Glaucoma Study Consortium Investigators.

    更新日期:2019-11-01 00:00:00

  • Latanoprost or brimonidine as treatment for elevated intraocular pressure: multicenter trial in the United States.

    abstract:PURPOSE:To compare the efficacy and tolerability of latanoprost or brimonidine in patients with elevated intraocular pressure (IOP). MATERIALS AND METHODS:This prospective, randomized, masked-evaluator, parallel-group, multicenter study in the United States included patients with primary open angle glaucoma or ocular ...

    journal_title:Journal of glaucoma

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1097/01.ijg.0000151881.99607.4e

    authors: Camras CB,Sheu WP,United States Latanoprost-Brimonidine Study Group.

    更新日期:2005-04-01 00:00:00

  • Provider Agreement in the Assessment of Glaucoma Progression Within a Team Model.

    abstract:PURPOSE:Glaucoma specialists and optometrists who work in a team model at a single institution utilize a common definition of glaucoma progression and treatment algorithm. The purpose of this study was to assess the consistency of agreement in identifying glaucoma progression among glaucoma specialists and optometrists...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0000000000000994

    authors: Shah SM,Choo C,Odden J,Zhao B,Fang C,Schornack M,Stalboerger G,Bennett JR,Khanna CL

    更新日期:2018-08-01 00:00:00

  • Corneal parameters and difference between goldmann applanation tonometry and dynamic contour tonometry in normal eyes.

    abstract:PURPOSE:To compare the difference between 2 methods of measuring the intraocular pressure (IOP), namely, Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT) and to study the relationship with the corneal parameters in patients with no glaucoma signs. METHODS:One hundred and eighteen eyes of 118 he...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e31816224bd

    authors: Lanza M,Borrelli M,De Bernardo M,Filosa ML,Rosa N

    更新日期:2008-09-01 00:00:00

  • Using the early postoperative intraocular pressure to predict pressure control after a trabeculectomy.

    abstract:PURPOSE:The goal of this study was to identify the early postoperative intraocular pressure (IOP) that predicts low pressure control after a trabeculectomy with mitomycin C. MATERIALS AND METHODS:This study retrospectively analyzed the medical records of the initial trabeculectomy with mitomycin C in patients with pri...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/IJG.0b013e318285fd7d

    authors: Okimoto S,Kiuchi Y,Akita T,Tanaka J

    更新日期:2014-08-01 00:00:00

  • Correlation of automated visual field parameters and peripapillary nerve fiber layer thickness as measured by scanning laser polarimetry.

    abstract:PURPOSE:To correlate Humphrey visual field mean sensitivity and peripapillary nerve fiber layer thickness as measured by scanning laser polarimetry. METHODS:The authors studied 54 eyes of 34 patients who visited a university-based glaucoma clinic and had undergone scanning laser polarimetry and Humphrey perimetry with...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章

    doi:10.1097/00061198-200008000-00001

    authors: Kwon YH,Hong S,Honkanen RA,Alward WL

    更新日期:2000-08-01 00:00:00