Abstract：
PURPOSE:To evaluate the incidence of glaucoma and elevation of intraocular pressure (IOP) in patients with inflammatory eye disease. METHODS:Retrospective review of medical records of 391 consecutive patients with uveitis attending a uveitis clinic of an academic Department of Ophthalmology from January 1999 to August 2002. Demographic, ocular and systemic variables were recorded. The diagnosis and treatment of uveitis were recorded. Uveitis was classified according to standard anatomic, etiological and clinical criteria. "Glaucoma" was defined as elevated IOP (>21 mm Hg) or glaucomatous optic nerve damage requiring medical and/or surgical anti-glaucoma treatment. Kaplan-Maier analysis and log-rank tests were used to evaluate and compare the incidence of glaucoma. RESULTS:The incidence of glaucoma as defined above at 3 and 12 months after acute uveitis was 7.6%. In patients with chronic uveitis (n = 337), the incidence of glaucoma at 1 and 5 years was 6.5% and 11.1%, respectively. There was no statistically significant difference in the incidence of glaucoma between different types of uveitis, idiopathic versus non-idiopathic, and among anterior, intermediate, posterior and panuveitis. Visual loss occurred more frequently in patients with glaucoma than in patients without glaucoma. CONCLUSION:In patients with chronic inflammatory eye disease, the presence of glaucoma was associated with an increasing risk of visual loss. The incidence of glaucoma increased with time and was similar among the different types of uveitis.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Neri P,Azuara-Blanco A,Forrester JVdoi
10.1097/01.ijg.0000146391.77618.d0keywords:
subject
Has Abstractpub_date
2004-12-01 00:00:00pages
461-5issue
6eissn
1057-0829issn
1536-481Xpii
00061198-200412000-00006journal_volume
13pub_type
杂志文章abstract：PURPOSE:The purpose of this study was to examine the long-term efficacy and safety of dorzolamide (a topical carbonic anhydrase inhibitor, previously known as MK-507) as an ocular hypotensive agent. METHODS:This open-labeled, multicenter, 52-week trial enrolled patients with primary open-angle glaucoma or ocular hyper...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：PURPOSE:To investigate the efficacy and safety of a treatment strategy with latanoprost and dorzolamide in primary pediatric glaucoma patients partially responsive to surgery. PATIENTS AND METHODS:Children with primary pediatric glaucoma having postsurgical untreated intraocular pressure (IOP) between 22 and 26 mm Hg ...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/IJG.0000000000000773
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:To evaluate aqueous levels of vascular endothelial growth factor (VEGF) and endothelin-1 (ET-1) in patients with branch retinal vein occlusion (BRVO) with and without normal tension glaucoma (NTG), and to assess the therapeutic efficacy of intravitreal bevacizumab (IVB) in these patients. METHODS:Sixteen eyes ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3182312047
更新日期：2013-02-01 00:00:00
abstract：PURPOSE:To determine if laser iridotomy altered the anterior segment anatomy of patients with plateau iris configuration. METHODS:Twenty eyes of 9 female and 1 male patients were imaged using an ultrasound biomicroscope within 19 weeks before and 52 weeks after laser iridotomy. Measurements obtained included the anter...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000151687.96785.03
更新日期：2005-04-01 00:00:00
abstract：:A 54-year-old woman who presented with photopsia was found to have elevated intraocular pressure in both eyes and optic disc cupping in the right eye. Angle infiltration was noted on gonioscopy. She was previously been diagnosed with metastatic breast cancer. This case report describes a rare case of glaucoma as a com...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001445
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To study the additive effect of latanoprost 0.005% in patients who have uncontrolled intraocular pressure (IOP) using timolol 0.5% and dorzolamide 2%. METHODS:Fifty-two consecutive patients with open-angle glaucoma who were using timolol and dorzolamide and were considered to have IOP above their defined targe...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200004000-00010
更新日期：2000-04-01 00:00:00
abstract：PURPOSE:The purpose of this study is to describe the outcomes of mitomycin C (MMC)-augmented trabeculectomy performed following a failed MMC-augmented XEN-45 implantation. DESIGN:Retrospective case series. METHODS:All consecutive cases of MMC-augmented trabeculectomy performed after MMC-augmented XEN-45 in the Glauco...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001000
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:This meta-analysis aims to comprehensively evaluate the association between total homocysteine (tHcy) levels, serum folic acid, vitamin B12, vitamin B6 levels, methylenetetrahydrofolate reductase (MTHFR) C677T genotype, and risk of normal-tension glaucoma (NTG). MATERIALS AND METHODS:A systematic search of ...
journal_title：Journal of glaucoma
pub_type： 杂志文章,meta分析
doi：10.1097/IJG.0000000000000269
更新日期：2016-02-01 00:00:00
abstract：:Exfoliation syndrome (XFS) is considered to be a disease of extracellular matrix. Here we review key experimental evidence of aberrations in structure, expression, and function of glycoproteins, complex carbohydrates, and glycosaminoglycans found in extracellular matrix components forming exfoliation material in patie...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0000000000000118
更新日期：2014-10-01 00:00:00
abstract：:PRéCIS:: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted. PURPOSE:The main purpose of this study was to evaluate the ...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1097/IJG.0000000000001209
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To investigate corneal viscoelasticity in primary open-angle glaucoma patients with and without diabetes mellitus, and to correlate corneal hysteresis (CH) with central corneal thickness (CCT). METHODS:In this cross-sectional study, 44 primary open-angle glaucoma patients [19 with diabetes (34 eyes) and 25 wit...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181b4caa1
更新日期：2010-06-01 00:00:00
abstract：PURPOSE:The purpose of this study was to report a case of recurrent conjunctival erosion and XEN Gel Stent exposure after implantation in a primary open-angle glaucoma patient. Minimally invasive glaucoma surgery (MIGS) is a new approach in glaucoma surgery, and there is a lack of published data with regard to the mana...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001146
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To evaluate the effect of a latanoprost/timolol fixed combination (LTFC) versus a latanoprost and timolol gel-forming solution unfixed combination (LTuFC) on daytime intraocular pressure (IOP) levels and fluctuations. METHODS:This was an 8-week, randomized, parallel-group study. Ninety eyes of 90 patients diag...
journal_title：Journal of glaucoma
pub_type： 杂志文章,随机对照试验
doi：10.1097/IJG.0000000000000170
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:Our purpose was to investigate the effects of the calcium channel blocker verapamil on intraocular pressure and blood circulation in the human optic nerve head. METHODS:The effects of three different concentrations of topical verapamil (0.063%, 0.125%, and 0.25%) on intraocular pressure and optic nerve head ca...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-06-01 00:00:00
abstract：:The mainstay of open-angle glaucoma surgery involves subconjunctival drainage of aqueous fluid. Insertion of the XEN Gel Stent leads to formation of a subconjunctival bleb to assist in the drainage of aqueous fluid and offers the advantage of ease and speed of insertion with conjunctival sparing over traditional surgi...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001058
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:To determine the optimal OCT-3 scanning protocol. METHODS:Normal subjects, ocular hypertensive, and open-angle glaucoma patients were enrolled. The "fast" RNFL scan protocol consists of 3 consecutive circular scans, each containing 256 A-scans obtained in a single 1.92 second session. The "regular" RNFL scan p...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200404000-00010
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:The purpose of this study was to perform a comparison of static and dynamic pupillometry measurements in patients with clinically unilateral pseudoexfoliation syndrome (PES) and age-matched controls. METHODS:This prospective cross-sectional study consisted of 38 patients with unilateral PES and 40 control part...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000953
更新日期：2018-06-01 00:00:00
abstract：:PRéCIS:: In primary open-angle glaucoma (POAG), unlogged mean macular hemifield visual field sensitivity correlates significantly better with superficial capillary vessel density (VD) than with ganglion cell complex (GCC) thickness of the opposite macular hemifield. PURPOSE:The aim of this study was to compare the re...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001441
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To evaluate the peripapillary retinal nerve fiber layer (RNFL), ganglion cell complex, and macular thickness as well as their correlation with the severity of diseases. MATERIALS AND METHODS:This is a cross-sectional study and comparing both eyes of 26 patients with primary open-angle glaucoma, 25 patients wit...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000239
更新日期：2016-07-01 00:00:00
abstract：:Destruction of the ciliary body, an option in glaucoma surgical treatment, can be performed using various methods. Laser energy, now the principle source for cyclodestruction, can be delivered in a transpupillar, transvitreal in conjunction with a vitrectomy and transscleral manner. The current technique for endocyclo...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31826981b1
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To evaluate the risk of developing glaucoma in patients taking systemic fluoroquinolones. METHODS:A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed wi...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31829463c1
更新日期：2014-09-01 00:00:00
abstract：PURPOSES:To evaluate the effects of axial length and age on the circumpapillary retinal nerve fiber layer (cpRNFL) and the inner macular parameters measured using 3 spectral-domain optical coherence tomography (OCT) instruments. METHODS:A total of 102 normal eyes (1 eye per subject) were imaged using Cirrus, RTVue, an...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000216
更新日期：2016-04-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of selective laser trabeculoplasty (SLT) versus argon laser trabeculoplasty (ALT) in lowering the intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension secondary to pseudoexfoliation. DESIGN:Multicentered randomized clinical trial. PARTICIPANTS:A total...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/IJG.0b013e31829e55e4
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To report a case of secondary pulmonary arterial hypertension (PAH) and the relationship of intraocular pressure (IOP) change with right ventricular diameter (RVD) and brain natriuretic peptide (BNP). METHODS:Case report. PATIENT:A 22-year-old woman with dilated and congested conjunctival and episcleral veins...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000371
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:Recent studies have found nocturnal reductions in systemic arterial blood pressure associated with progressive visual field loss in glaucoma. Although ocular ischemia has been hypothesized to link these two phenomena, it remains unknown if perfusion of the eye is reduced during the night in patients with glauco...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：PURPOSE:The mechanism by which the prostaglandin F2alpha-related antiglaucoma compound isopropyl unoprostone (referred to as unoprostone) reduces intraocular pressure is largely unknown. Another prostaglandin F2alpha-related compound, latanoprost, influences the activities of matrix metalloproteinases in ciliary muscle...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200108000-00005
更新日期：2001-08-01 00:00:00
abstract：PURPOSE:Optic disc photographs of 750 patients attending a glaucoma practice were examined to identify focal peripapillary arteriolar narrowing. METHODS:A subgroup of 110 of these patients' photographs, who had also had finger circulation tested for vasospasm to cold, were divided into patients with peripapillary foca...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
abstract：PURPOSE:To elucidate the relationship between macular retinal thickness and corresponding superior or inferior visual hemifield defects in glaucoma patients. METHODS:Thirty-nine eyes of 39 patients with open-angle glaucoma showed superior or inferior hemifield defects (superior hemifield defects, 27 eyes; inferior hem...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318225472a
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:We assessed vision-related quality of life (VR-QOL) in glaucoma patients and examined the relationship between VR-QOL and indices of visual function and subjective symptoms. PATIENTS AND METHODS:Four hundred seventy-two glaucoma patients completed a questionnaire concerning VR-QOL and subjective symptoms of gl...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/IJG.0000000000000221
更新日期：2016-03-01 00:00:00
abstract：PRECIS:Hypotony keratopathy is a potential complication of hypotony following trabeculectomy and successful treatment depends on increasing intraocular pressure (IOP). PURPOSE:To evaluate corneal decompensation in patients following trabeculectomy with adjuvant mitomycin C (MMC). We propose "hypotony keratopathy" as a...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001425
更新日期：2020-02-01 00:00:00
