Health Economic Analysis in Glaucoma.


:The pressure on glaucoma services is ever-growing, and policymakers seek robust cost-effectiveness arguments in their decisions around resource allocation. The benefits of glaucoma are in preventing or delaying a future loss of vision and associated quality of life, and this expectation is quantified using a metric called utility which can be compared against other disease states. In recent clinical trials lasting up to 3 years, it has been difficult to show a difference in utility between glaucoma treatments in this limited period of time. When it comes to cost, the direct medical costs are only part of the broad range of costs that glaucoma brings to patients and communities, and the estimation of these costs can be difficult and imprecise. While the cost-effectiveness of glaucoma care, in general, is not in dispute, especially over longer time frames, the inability to measure changes in utility in shorter time frames impedes the uptake of innovations around the world. A number of approaches to improve the sensitivity and specificity of utility measurements are under investigation.


J Glaucoma


Journal of glaucoma


Park I,Gale J,Skalicky SE




Has Abstract


2020-04-01 00:00:00












  • Slit-lamp Needling of the Anterior Capsule for Aqueous Misdirection After Hyaloido-zonulectomy and Iridectomy.

    abstract:INTRODUCTION:We present a case of persistent aqueous misdirection, after Ahmed glaucoma valve surgery, despite undergoing an anterior vitrectomy with hyaloido-zonulectomy and iridectomy. CASE REPORT:A 73-year-old female patient, 4 months after phacotrabeculectomy, was referred with persistent high intraocular pressure...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Mardelli PG,Mardelli ME

    更新日期:2018-04-01 00:00:00

  • Ahmed Valve Upstream Obstruction Caused by Fibrous Ingrowth: Surgical Approach.

    abstract::Glaucoma secondary to penetrating keratoplasty can be challenging and multiple surgeries may be needed to control the intraocular pressure (IOP), including the use of glaucoma drainage implants. However, late failure of these drainage implant surgery is common, mostly because of excessive scarring or bleb encapsulatio...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Medeiros Pinto J,Pinto Ferreira N,Abegão Pinto L

    更新日期:2017-10-01 00:00:00

  • Comparison of symptomatic and asymptomatic, chronic, primary angle-closure glaucoma, open-angle glaucoma, and controls.

    abstract:PURPOSE:To determine the clinical features and anatomic parameters in asymptomatic (creeping) and symptomatic, chronic, primary angle-closure glaucoma (PACG) as compared with open-angle glaucoma (OAG) and with control subjects with normal eyes. METHODS:Forty consecutive patients with each of the following four types o...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Sihota R,Gupta V,Agarwal HC,Pandey RM,Deepak KK

    更新日期:2000-06-01 00:00:00

  • Molteno implant versus trabeculectomy with adjunctive intreoperative mitomycin-C in high-risk glaucoma patients.

    abstract:PURPOSE:The Molteno implant is one of the most widely used drainage devices for the management of complicated glaucoma. Antiproliferative agents such as mitomycin-C (MMC) have markedly improved the outcome of glaucoma filtering surgery. This case control study compares the results of these two techniques in the managem...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Sayyad FE,Helal M,Elsherif Z,El-Maghraby A

    更新日期:1995-04-01 00:00:00

  • Phaco-viscocanalostomy versus phaco-trabeculotomy: a middle-term study.

    abstract:PURPOSE:To compare the surgical outcomes between phaco-viscocanalostomy and phaco-trabeculotomy in open-angle glaucoma. PATIENTS AND METHODS:In a nonrandomized, retrospective clinical study, 110 eyes underwent phaco-viscocanalostomy (VCS group), and 110 eyes underwent phaco-trabeculotomy (LOT group). The mean follow-u...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Park M,Hayashi K,Takahashi H,Tanito M,Chihara E

    更新日期:2006-10-01 00:00:00

  • Primary Open-angle Glaucoma and Increased Risk of Chronic Kidney Disease.

    abstract:PRECIS:The association between primary open-angle glaucoma (POAG) and subsequent development of chronic kidney disease (CKD) was investigated using a nationwide, population-based, retrospective cohort in South Korea. POAG increases the risk of subsequent CKD development. PURPOSE:The purpose of this study was to invest...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Park SJ,Byun SJ,Park JY,Kim M

    更新日期:2019-12-01 00:00:00

  • A new model of glaucoma filtering surgery in the rat.

    abstract:PURPOSE:The most common reason for long-term failure of glaucoma filtering surgery (GFS) is scarring of the external filtering "bleb" tissues. The identification of the factors that mediate this process, as well as the development and initial testing of new therapies to limit scarring is enhanced by the use of appropri...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Sherwood MB,Esson DW,Neelakantan A,Samuelson DA

    更新日期:2004-10-01 00:00:00

  • Clinical Implications of In Vivo Lamina Cribrosa Imaging in Glaucoma.

    abstract::The lamina cribrosa (LC) is a multilayered, collagenous, sieve-like structure at the deep optic nerve head, and is presumed to be the primary site of axonal injury. According to biomechanical theory, intraocular pressure-induced posterior deformation of the LC causes blockage of axonal transport and alters the ocular ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,评审


    authors: Kim YW,Jeoung JW,Kim YK,Park KH

    更新日期:2017-09-01 00:00:00

  • Evaluating the Laser Output of the Micropulse P3 Laser Delivery Device Following Repeated Use.

    abstract:PRECIS:Repeated use of the Micropulse P3 (MP3) probe during micropulse transscleral cyclophotocoagulation is associated with an increase in laser output over time. PURPOSE:The purpose of this study was to examine the laser efficacy of the MP3 probe following repeated use. METHODS:This was an observational study carri...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Lun K,Suwandono ME,Koh V,Chew PT

    更新日期:2019-08-01 00:00:00

  • Comparison of scanning laser polarimetry and optical coherence tomography in quantitative retinal nerve fiber assessment.

    abstract:PURPOSE:To investigate the relationship between retinal nerve fiber layer (RNFL) measurements in corresponding areas obtained with scanning laser polarimetry and optical coherence tomography and to compare their discriminating ability in the diagnosis of preperimetric and perimetric glaucoma. PATIENTS AND METHODS:Thre...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Schrems WA,Mardin CY,Horn FK,Juenemann AG,Laemmer R

    更新日期:2010-02-01 00:00:00

  • Imaging visual cortical structure and function in vivo.

    abstract::The recent advent of in vivo two-photon microscopy has allowed the repeat imaging of cortical structures at microscopic resolution within intact brains. Recent data obtained using this imaging technique shows that dendritic spines, the postsynaptic sites of the majority of excitatory synapses in the central nervous sy...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,评审


    authors: Majewska AK

    更新日期:2013-06-01 00:00:00

  • Risk factors for decompression retinopathy after glaucoma surgery.

    abstract:PURPOSE:To evaluate the risk factors for decompression retinopathy after glaucoma surgery. METHODS:We reviewed the medical records of patients who underwent a trabeculectomy or Ahmed valve implantation and divided them into 2 groups by the development of decompression retinopathy. Various factors were compared between...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Jung KI,Lim SA,Lopilly Park HY,Park CK

    更新日期:2014-12-01 00:00:00

  • Ahmed glaucoma valve implantation with tube insertion through the ciliary sulcus in pseudophakic/aphakic eyes.

    abstract:PURPOSE:To report the efficacy and safety of Ahmed glaucoma valve (AGV) insertion into the ciliary sulcus in pseudophakic/aphakic patients. PATIENTS AND METHODS:A chart review was done on patients with uncontrolled glaucoma, who underwent AGV implantation with tube inserted into the ciliary sulcus. Baseline intraocula...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Eslami Y,Mohammadi M,Fakhraie G,Zarei R,Moghimi S

    更新日期:2014-02-01 00:00:00

  • Radial Peripapillary Capillary Density Measurement Using Optical Coherence Tomography Angiography in Early Glaucoma.

    abstract:PURPOSE:The purpose of the study was to compare radial peripapillary capillary (RPC) density between normal subjects and patients with early primary open-angle glaucoma (POAG) using optical coherence tomography angiography (OCT-A). MATERIALS AND METHODS:A total of 24 patients with early POAG and age-matched 52 normal ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Mansoori T,Sivaswamy J,Gamalapati JS,Balakrishna N

    更新日期:2017-05-01 00:00:00

  • Decreased cardiovagal regulation in exfoliation syndrome.

    abstract:PURPOSE:To investigate the parasympathetic cardiovascular regulation, baroreflex sensitivity (BRS), and pulse wave velocity (PWV) in exfoliation syndrome (XFS). METHODS:Heart rate variability indices [standard deviation of all RR intervals (SDNN); the mean of absolute successive differences (RMSSD); the percentage of ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Visontai Z,Horváth T,Kollai M,Holló G

    更新日期:2008-03-01 00:00:00

  • Secondary Epiretinal Membrane After Trabeculectomy.

    abstract:PURPOSE:To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy. METHODS:We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence t...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Vieira L,Cabugueira A,Borges B,Carvalho V,Noronha M,Abegão Pinto L,Reina M,Dutra Medeiros M

    更新日期:2016-06-01 00:00:00

  • Relationship between pattern electroretinogram, standard automated perimetry, and optic nerve structural assessments.

    abstract:PURPOSE:To examine the relationship between retinal ganglion cell function measured using pattern electroretinogram optimized for glaucoma screening (PERGLA), retinal nerve fiber layer (RNFL) thickness, and optic nerve head topography. METHODS:Twenty-nine normal, 28 glaucoma, and 37 glaucoma suspect volunteers were en...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Sehi M,Pinzon-Plazas M,Feuer WJ,Greenfield DS

    更新日期:2009-10-01 00:00:00

  • Deep Sclerectomy With a New Nonabsorbable Uveoscleral Implant (Esnoper-Clip): 1-Year Outcomes.

    abstract:PURPOSE:To report the safety and the effectiveness of deep sclerectomy (DS) with a new nonabsorbable uveoscleral hema implant (Esnoper-Clip) designed to increase trabecular and uveoscleral outflow and to achieve higher intrascleral blebs. MATERIALS AND METHODS:Twenty-seven eyes of 27 patients with open-angle glaucoma,...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Loscos-Arenas J,Parera-Arranz A,Romera-Romera P,Castellvi-Manent J,Sabala-Llopart A,de la Cámara-Hermoso J

    更新日期:2015-08-01 00:00:00

  • Optic Nerve Head Drusen: Imaging Using Optical Coherence Tomography Angiography.

    abstract:PURPOSE:To describe findings and utility of optical coherence tomography angiography (OCTA) in optic nerve head drusen (ONHD). OBSERVATIONS:A 57-year-old white man presented with a decrease in contrast sensitivity of the inferior visual field in both eyes. Clinical examination, visual fields, optical coherence tomogra...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Flores-Reyes E,Hoskens K,Mansouri K

    更新日期:2017-09-01 00:00:00

  • A Novel Method of Extending Glaucoma Drainage Tube: "Tube-in-Tube" Technique.

    abstract:PURPOSE:To describe a new and simple technique of glaucoma tube extension that carries several advantages over previously described techniques. PATIENTS AND METHODS:A retrospective noncomparative case series of 3 patients (1 adult and 2 pediatric cases) with glaucoma tube retraction managed by the "tube-in-tube" techn...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Chiang MY,Camuglia JE,Khaw PT

    更新日期:2017-02-01 00:00:00

  • Microbiologic identification of bleb-related delayed-onset endophthalmitis caused by moraxella species.

    abstract:PURPOSE:To report the clinical presentation and outcome of delayed-onset endophthalmitis caused by Moraxella species and to evaluate the eubacterial polymerase chain reaction (PCR) in aqueous humor samples for the microbiologic diagnosis. PATIENTS AND METHODS:Seven patients with bleb-related delayed onset-endophthalmi...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,多中心研究


    authors: Cornut PL,Chiquet C,Bron A,Romanet JP,Lina G,Lafontaine PO,Benito Y,Pechinot A,Burillon C,Vandenesch F,Denis P,FRIENDS Group.

    更新日期:2008-10-01 00:00:00

  • Relief of periorbital pain after acute angle closure glaucoma attack by botulinum toxin type A.

    abstract:PURPOSE:To assess the efficacy and safety of botulinum toxin type A (BoNT-A) injection in patients suffering from intractable periorbital pain after acute angle closure glaucoma (AACG). PATIENTS AND METHODS:In this prospective randomized intervention study, 19 patients suffering from periorbital pain after an AACG att...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,随机对照试验


    authors: Chien KH,Lu DW,Chen YH,Cheng JH,Chen JT

    更新日期:2010-10-01 00:00:00

  • Modified deep sclerectomy (D-lectomy MMC) for primary open-angle glaucoma: preliminary results.

    abstract:PURPOSE:To evaluate the outcome of modified deep sclerectomy [D-lectomy mitomycin C (MMC)] for medically refractory glaucoma patients. METHODS:In a retrospective comparative study, the surgical outcome in 1 eye each of 31 patients who underwent D-lectomy MMC was compared with that of 91 eyes of 91 patients who underwe...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Chihara E,Okazaki K,Takahashi H,Shoji T,Adachi H,Hayashi K

    更新日期:2009-02-01 00:00:00

  • Corneal viscoelasticity differences between diabetic and nondiabetic glaucomatous patients.

    abstract:PURPOSE:To investigate corneal viscoelasticity in primary open-angle glaucoma patients with and without diabetes mellitus, and to correlate corneal hysteresis (CH) with central corneal thickness (CCT). METHODS:In this cross-sectional study, 44 primary open-angle glaucoma patients [19 with diabetes (34 eyes) and 25 wit...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Castro DP,Prata TS,Lima VC,Biteli LG,de Moraes CG,Paranhos A Jr

    更新日期:2010-06-01 00:00:00

  • Outcomes of Trabeculectomy With Mitomycin-C in Uveitis Associated With Vogt-Koyanagi-Harada Disease.

    abstract:OBJECTIVES:To evaluate the outcomes of trabeculectomy with mitomycin-C (MMC) in uveitis associated with Vogt-Koyanagi-Harada disease (VKH). METHODS:Retrospective cohort study included 27 eyes of 15 patients with uveitic glaucoma associated with VKH disease who underwent trabeculectomy with MMC as a first glaucoma proc...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Almobarak FA,Alharbi AH,Morales J,Aljadaan I

    更新日期:2016-06-01 00:00:00

  • Association of the optic disc structure with the use of antihypertensive medications: the thessaloniki eye study.

    abstract:PURPOSE:To investigate the association of antihypertensive medications with optic disc structure by blood pressure (BP) level, in nonglaucoma subjects. DESIGN:Cross-sectional, population-based study. METHODS:A subset of Thessaloniki Eye Study participants was included in this study. Subjects were interviewed for medi...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Harris A,Topouzis F,Wilson MR,Founti P,Kheradiya NS,Anastasopoulos E,Gong G,Yu F,Jonescu-Cuypers CP,Pappas T,Koskosas A,Coleman AL

    更新日期:2013-09-01 00:00:00

  • Outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery.

    abstract:PURPOSE:To determine the outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery. PATIENTS AND METHODS:Retrospective, consecutive, noncomparative case series. Outcome measures were closure of bleb leak, intraocular pressure (IOP), and best ...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Panday M,Shantha B,George R,Boda S,Vijaya L

    更新日期:2011-08-01 00:00:00

  • Oral fluoroquinolones and risk of glaucoma.

    abstract:OBJECTIVE:To evaluate the risk of developing glaucoma in patients taking systemic fluoroquinolones. METHODS:A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed wi...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Yang L,Etminan M,Mikelberg FS

    更新日期:2014-09-01 00:00:00

  • Outcomes of surgical bleb revision for late-onset bleb leaks after trabeculectomy.

    abstract:PURPOSE:To describe the outcome of surgical bleb revision for late-onset bleb leaks after trabeculectomy. PATIENTS AND METHODS:Appropriate cases were identified. Qualified and complete success required intraocular pressure of 21 mm Hg or less with and without glaucoma medication use, respectively. Bleb survival was de...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章


    authors: Lin AP,Chung JE,Zhang KS,Chang MM,Orengo-Nania S,Gross RL,Chang PT

    更新日期:2013-01-01 00:00:00

  • A Role for Clusterin in Exfoliation Syndrome and Exfoliation Glaucoma?

    abstract::The multifunctional protein clusterin (CLU) is a secreted glycoprotein ubiquitously expressed throughout the body, including in the eye. Its primary function is to act as an extracellular molecular chaperone, preventing the precipitation and aggregation of misfolded extracellular proteins. Clusterin is commonly identi...

    journal_title:Journal of glaucoma

    pub_type: 杂志文章,评审


    authors: Wiggs JL,Kang JH,Fan B,Levkovitch-Verbin H,Pasquale LR

    更新日期:2018-07-01 00:00:00