Erythropoietin: a candidate neuroprotective agent in the treatment of glaucoma.

Abstract:

:Glaucoma is a progressive optic neuropathy that is the leading cause of irreversible blindness in the world. Although methods to lower intraocular pressure are the mainstay of glaucoma therapy, there are currently no available treatment modalities targeted at neuroprotection. Erythropoietin is a hematopoietic cytokine that has been shown to possess remarkable tissue-protective properties in preclinical models of neurodegeneration. As a result, there is a growing interest to explore the neuroprotective properties of erythropoietin as a possible therapeutic agent in neuropathic diseases of the eye such as glaucoma. Initial results in animal models have been promising, but further studies are needed to fully evaluate the safety and efficacy of this candidate neuroprotective agent in clinical trials.

journal_name

J Glaucoma

journal_title

Journal of glaucoma

authors

Tsai JC,Song BJ,Wu L,Forbes M

doi

10.1097/IJG.0b013e318156a556

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

567-71

issue

6

eissn

1057-0829

issn

1536-481X

pii

00061198-200709000-00010

journal_volume

16

pub_type

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