Scanning laser polarimetry with enhanced corneal compensation in patients with open-angle glaucoma.

Abstract:

AIMS:To compare the retinal nerve fiber layer thickness (RNFLT) parameters obtained with newly introduced GDx with enhanced corneal compensation (ECC) and those with GDx with variable corneal compensation (VCC) and to evaluate their reproducibility and the correspondence with visual field damage (VFD) in total or sectorized fields in association with refractive errors in open-angle glaucoma (OAG) patients. PATIENTS AND METHODS:Measurement reproducibility was assessed in 30 normal and 30 OAG eyes. Correlation between the RNFLT parameters and the corresponding VFD was evaluated in 58 OAG eyes. RESULTS:All parameters of both GDx VCC and ECC showed high intraclass correlation coefficients among the repeated measurements (0.89 to 0.99), suggesting good reproducibility. All RNFLT parameters were significantly correlated between VCC and ECC (intraclass correlation coefficient=0.58-0.92, P<0.001) though they were significantly different. In OAG eyes, correlation between temporal, superior, nasal, inferior, temporal average and mean deviation of VFD was similar in both algorithms (Rs=0.58 and 0.53, P<0.001). When the OAG eyes were subgrouped by refractive error at -5 D, the correlation was significant for both ECC and VCC in the lower myopic group (>-5 D) (Rs=0.71 and 0.74, P<0.0001) but was significant only for ECC in the higher myopic group (

journal_name

J Glaucoma

journal_title

Journal of glaucoma

authors

Saito H,Tomidokoro A,Yanagisawa M,Aihara M,Tomita G,Araie M

doi

10.1097/IJG.0b013e318133fb47

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

24-9

issue

1

eissn

1057-0829

issn

1536-481X

pii

00061198-200801000-00006

journal_volume

17

pub_type

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