Abstract：
PURPOSE:To determine whether the multifocal visual evoked potential (mfVEP) technique can detect early functional damage in ocular hypertensive (OHT) and glaucoma suspect (GS) patients with normal standard achromatic automated perimetry (SAP) results. PATIENTS AND METHODS:Twenty-five GS patients (25 eyes), 25 patients with OHT (25 eyes), and 50 normal controls (50 eyes) were enrolled in this study. All GS, OHT and normal control eyes had normal SAP as defined by a pattern standard deviation and mean deviation within the 95% confidence interval and a glaucoma hemifield test within normal limits on the Humphrey visual field 24-2 program. Eyes with GS had optic disc changes consistent with glaucoma with or without raised intraocular pressure (IOP), and eyes with OHT showed no evidence of glaucomatous optic neuropathy and IOPs >or=22 mm Hg. Monocular mfVEPs were obtained from both eyes of each subject using a pattern-reversal dartboard array with 60 sectors. The entire display had a radius of 22.3 degrees. The mfVEPs, for each eye, were defined as abnormal when either the monocular or interocular probability plot had a cluster of 3 or more contiguous points with P<0.05 and at least 2 of these points with P<0.01. RESULTS:The mfVEP results were abnormal in 4% of the eyes from normal subjects. Abnormal mfVEPs were detected in 20% of the eyes of GS patients and 16% of the eyes of OHT patients. Significantly more mfVEP abnormalities were detected in GS patients than in normal controls. However, there was no significant difference in mfVEP results between OHT patients and normal controls. CONCLUSIONS:The mfVEP technique can detect visual field deficits in a minority of eyes with glaucomatous optic disks and normal SAP results.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Thienprasiddhi P,Greenstein VC,Chu DH,Xu L,Liebmann JM,Ritch R,Hood DCdoi
10.1097/01.ijg.0000212237.26466.0esubject
Has Abstractpub_date
2006-08-01 00:00:00pages
321-7issue
4eissn
1057-0829issn
1536-481Xpii
00061198-200608000-00009journal_volume
15pub_type
杂志文章abstract：PURPOSE:To determine whether a structure-function model developed for normal age-related losses of retinal ganglion cells also models the retinal ganglion cell losses in glaucomatous optic neuropathy. METHODS:The model to relate age-related loss of retinal nerve fiber layer thickness and reduced sensitivity for standa...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31820bcfbe
更新日期：2012-02-01 00:00:00
abstract：:The in vivo response to laser trabeculoplasty (LTP) was evaluated by measuring the incorporation of thymidine into DNA in the nuclei of trabecular meshwork cells. incorporation into DNA was analyzed by light microscopic autoradiography and by scintillation counting of trabecular extracts. Sixteen cats received argon L...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：AIMS:An observational study to determine the safety and efficacy of filtering surgery employing a microlumen aqueous drainage device (InnFocus MicroShunt), used intraoperatively with Mitomycin C, implanted alone or in combination with phacoemulsification. MATERIALS AND METHODS:Single-site, prospective, nonrandomized s...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000368
更新日期：2016-02-01 00:00:00
abstract：PRECIS:The VisuALL head-mounted perimetry in normal subjects and glaucoma patients had a moderate to strong correlation with the Humphrey Field Analyzer (HFA). PURPOSE:Visual field testing has a vital role in diagnosing and managing glaucoma. The current clinical practice relies on large, table-based testing units. Th...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001670
更新日期：2021-01-01 00:00:00
abstract：PRECIS:Micropulse trans-scleral cyclophotocoagulation is only moderately effective in lowering intraocular pressure and useful as an adjunct procedure to other glaucoma surgeries. There was a small risk of loss of vision, prolonged hypotony and phthisis bulbi. AIMS:To determine the efficacy and safety of a single micr...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001729
更新日期：2020-10-29 00:00:00
abstract：PURPOSE:The American Academy of Ophthalmology Preferred Practice Patterns for angle closure and open-angle glaucoma (OAG) patients recommends performing bilateral gonioscopy upon initial presentation to evaluate the possibility of narrow angle or angle-closure glaucoma (ACG) and then repeating the examination at least ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000212287.62798.8f
更新日期：2006-12-01 00:00:00
abstract：PRECIS:As the only microinvasive glaucoma surgery (MIGS) with a reusable component, the cost per procedure of endoscopic cyclophotocoagulation (ECP) diminishes with each successive use. We present a cost comparison of ECP with other MIGS devices, based on our clinical practice. PURPOSE:ECP delivers diode laser via a r...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001245
更新日期：2019-06-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of a tube fenestration stented with a 10-0 polyglactin suture for controlling early postoperative intraocular pressure (IOP) after Baerveldt glaucoma implant (BGI) surgery. METHODS:The medical records of 110 patients (119 eyes) who underwent BGI surgery with a tube fenestrat...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000885
更新日期：2018-03-01 00:00:00
abstract：PURPOSE:Management of a case of glaucoma secondary to an iris metastasis is reported. RESULTS:A 31-year-old woman developed glaucoma secondary to a metastatic tumor to the iris. Anti-glaucoma medication failed to control the increase in intraocular pressure (IOP). However, diode laser cyclophotocoagulation controlled ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:We present a case of conjunctival melting over the tube of a glaucoma shunt, which was successfully repaired with amniotic membrane transplantation. ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000212292.93292.80
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To determine the outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery. PATIENTS AND METHODS:Retrospective, consecutive, noncomparative case series. Outcome measures were closure of bleb leak, intraocular pressure (IOP), and best ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181e87efc
更新日期：2011-08-01 00:00:00
abstract：:Variants in LOXL1 are significantly associated with exfoliation syndrome (XFS), however the impact of the associated variants on disease development is not yet understood. Initially the associated missense changes, R141L and G153D, were considered to be pathogenic alleles. Flipping of the risk allele in certain popula...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0000000000000124
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To correlate Humphrey visual field mean sensitivity and peripapillary nerve fiber layer thickness as measured by scanning laser polarimetry. METHODS:The authors studied 54 eyes of 34 patients who visited a university-based glaucoma clinic and had undergone scanning laser polarimetry and Humphrey perimetry with...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200008000-00001
更新日期：2000-08-01 00:00:00
abstract：PURPOSE:To assess the comparative efficacy and safety of primary deep sclerectomy (DS) augmented with subconjunctival Bevacizumab and intraoperative Mitomycin C (MMC). METHODS:Retrospective, comparative case-control series of consecutive primary DS between January 2008 and December 2010. Seventy-five eyes of 73 patien...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3182883c0c
更新日期：2015-01-01 00:00:00
abstract：:Treatment with noncardioselective beta-adrenoceptor antagonists (e.g., 0.5% timolol or 0.5% levobunolol) is standard practice for lowering elevated intraocular pressure (IOP). However, because there are risks and side effects associated with the use of these agents, a lower, yet still effective, dose may be preferred....
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-199201040-00005
更新日期：1992-01-01 00:00:00
abstract：:The recent advent of in vivo two-photon microscopy has allowed the repeat imaging of cortical structures at microscopic resolution within intact brains. Recent data obtained using this imaging technique shows that dendritic spines, the postsynaptic sites of the majority of excitatory synapses in the central nervous sy...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0b013e3182934a30
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To compare the results of Ahmed glaucoma valve (AGV) implantation in eyes containing silicone oil to those without silicone oil. METHODS:This was a multicenter, retrospective, comparative study of 94 eyes in 94 patients with mean follow-up of 2 years, comparing surgical outcomes in eyes with silicone oil (N=47...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318182ede3
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:To report 2-year results of deep sclerectomy (DS) with mitomycin C and the uveoscleral implant Esnoper-Clip (AJL Ophthalmics, Álava, Spain), a nonabsorbable hema implant, and the morphologic analysis of the surgical area with anterior segment optical coherence tomography (AS-OCT). MATERIALS AND METHODS:In tota...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000756
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:To elucidate the relationship between macular retinal thickness and corresponding superior or inferior visual hemifield defects in glaucoma patients. METHODS:Thirty-nine eyes of 39 patients with open-angle glaucoma showed superior or inferior hemifield defects (superior hemifield defects, 27 eyes; inferior hem...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318225472a
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation (PEX) syndrome, an age-related, systemic, elastic microfibrillopathy, is characterized by fibrillar-granular deposits in the anterior segment of the eye. Although not representing a true amyloidosis, PEX syndrome shares some features with amyloid disorders, such as Alzheimer disease. It has be...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181ca76c4
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To determine the level of adherence to the American Academy of Ophthalmology preferred practice pattern (PPP) guidelines for quality primary open-angle glaucoma (POAG) and POAG suspect (POAGS) care among retail-based optometrists. METHODS:Patients with a diagnosis of POAG or POAGS who participated in a telemed...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001093
更新日期：2018-12-01 00:00:00
abstract：PURPOSE:To report a case of secondary pulmonary arterial hypertension (PAH) and the relationship of intraocular pressure (IOP) change with right ventricular diameter (RVD) and brain natriuretic peptide (BNP). METHODS:Case report. PATIENT:A 22-year-old woman with dilated and congested conjunctival and episcleral veins...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000371
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:To report the clinical presentation and outcome of delayed-onset endophthalmitis caused by Moraxella species and to evaluate the eubacterial polymerase chain reaction (PCR) in aqueous humor samples for the microbiologic diagnosis. PATIENTS AND METHODS:Seven patients with bleb-related delayed onset-endophthalmi...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/IJG.0b013e31816299ec
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To evaluate the usefulness of day-long sequential office measurements of intraocular pressure (IOP) to make therapeutic decisions in patients with progressive glaucomatous damage despite apparently 'controlled' IOP. METHODS:We reviewed the records of 93 consecutive glaucoma patients (185 eyes) who underwent se...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000159125.34241.79
更新日期：2005-06-01 00:00:00
abstract：PRECIS:Silica nanoparticles (SiNPs), which are potential drug carriers for glaucoma treatment, may induce mild dose-dependent cytotoxicity but not so severe as to compromise a mammalian target of rapamycin (mTOR) pathway in immortalized trabecular meshwork (TM) cells. PURPOSE:Nanoparticle-based ophthalmic drug deliver...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001709
更新日期：2021-02-01 00:00:00
abstract：PURPOSE:To investigate the effects of topical instillation of 0.5% tranilast eye drops on intraocular pressure (IOP) and bleb formation after glaucoma filtering surgery. PATIENTS AND METHODS:This was a prospective, randomized, double-masked, and controlled clinical trial. A total of 52 eyes of 52 patients were randoml...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200204000-00008
更新日期：2002-04-01 00:00:00
abstract：PURPOSE:To determine if treatment with prostaglandin (PG) analogues affects keratocyte density as an indirect measure of extracellular matrix in the corneal stroma. PATIENTS AND METHODS:In this case control study, 129 eyes from 68 patients were examined: 52 eyes had only PG analogue therapy for at least 3 years, 37 ey...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181ca7c7a
更新日期：2010-12-01 00:00:00
abstract：SUMMARY:Subconjunctival fibrosis is one of the major causes of most bleb failures. To inhibit the wound-healing process and to achieve a better intraocular pressure (IOP) lowering effect as well as bleb formation, we performed a sclerostomy using a THC:YAG laser (thulium, holmium, and chromium-doped yttrium-aluminum-ga...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：OBJECTIVE:To describe reoperations in the operating room for complications encountered within 90 days after glaucoma surgery at a single institution over a 2-year period. DESIGN:Retrospective case series. SUBJECTS:Adult patients who have undergone glaucoma surgery including a tube shunt, trabeculectomy with mitomycin...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001484
更新日期：2020-05-01 00:00:00
abstract：PURPOSE:To measure the change in intraocular pressure (IOP) of the fellow eye after glaucoma surgery in 1 eye. PATIENTS AND METHODS:In this prospective interventional study, 71 patients with primary and secondary glaucoma, undergoing glaucoma surgery in 1 eye were included. The IOP in the fellow eye following glaucoma...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000217
更新日期：2016-03-01 00:00:00
