Abstract:
PURPOSE:To determine the outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery. PATIENTS AND METHODS:Retrospective, consecutive, noncomparative case series. Outcome measures were closure of bleb leak, intraocular pressure (IOP), and best corrected visual acuity after patch grafting and complications from intervention. Complete success was defined as resolution of the bleb leak or hypotony, with IOP between 6 and 18 mm Hg. RESULTS:Fifty-eight eyes (57 patients) were included: 51 with bleb leaks and 7 with hypotonous maculopathy without a bleb leak. Eight eyes required scleral flap resuturing and 2 required scleral patch grafts in addition to free conjunctival patch grafting. The mean postoperative follow-up period was 112.65 ± 128.74 weeks (median 80.0 wk). At 6 weeks and final follow-up, the IOP increased from baseline of 4.41 ± 4.61 mm Hg (median 4.00 mm Hg) to 11.98 ± 6.25 mm Hg (median 11.50 mm Hg) (P<0.001) and 12.67 ± 4.83 mm Hg (median 12.00) (P<0.001), respectively. Visual acuity increased from baseline of 0.87 ± 0.95 logMAR (median 0.60) to 0.65 ± 0.80 logMAR (median 0.48) (P=0.001) and 0.76 ± 0.93 logMAR (median 0.48) (P=0.35) at 6 weeks and last follow-up, respectively. The complete and qualified success rates at the final follow-up were 75.8% and 79.3%, respectively. Failure events occurred in 12 (20.6%) eyes, including 2 eyes with hypotony, 5 with raised IOP, and 3 with postoperative bleb leaks. CONCLUSIONS:Free conjunctival patch grafting is a successful procedure for bleb repair and hypotony providing moderate IOP control with minimal postoperative complications in majority of patients.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Panday M,Shantha B,George R,Boda S,Vijaya Ldoi
10.1097/IJG.0b013e3181e87efcsubject
Has Abstractpub_date
2011-08-01 00:00:00pages
392-7issue
6eissn
1057-0829issn
1536-481Xjournal_volume
20pub_type
杂志文章abstract:PURPOSE:To report the clinical presentation and outcome of delayed-onset endophthalmitis caused by Moraxella species and to evaluate the eubacterial polymerase chain reaction (PCR) in aqueous humor samples for the microbiologic diagnosis. PATIENTS AND METHODS:Seven patients with bleb-related delayed onset-endophthalmi...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究
doi:10.1097/IJG.0b013e31816299ec
更新日期:2008-10-01 00:00:00
abstract:STUDY OBJECTIVES:The association between obstructive sleep apnea syndrome (OSAS) and retinal nerve fiber layer (RNFL) thickness has been examined in many studies. However, the findings are inconsistent. Our goal is to evaluate the association between OSAS and RNFL thickness by performing a meta-analysis. METHODS:We co...
journal_title:Journal of glaucoma
pub_type: 杂志文章,meta分析
doi:10.1097/IJG.0000000000000349
更新日期:2016-04-01 00:00:00
abstract:PURPOSE:To evaluate morphological features of filtering blebs after trabeculectomy with limbus-based versus fornix-based conjunctival flaps (LBCF and FBCF, respectively) using in vivo confocal microscopy (IVCM) and ultrasound biomicroscopy (UBM). PATIENTS AND METHODS:Seventy-five eyes of 62 patients with glaucoma were...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3182120a08
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:Axenfeld-Rieger syndrome is a genetically heterogeneous, autosomal dominant disorder that is characterized by anterior segment defects, glaucoma, and extraocular anomalies. This study examined the two genes known to cause Rieger syndrome, PITX2 and FOXC1, for mutations in five Brazilian families with Axenfeld-R...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200202000-00010
更新日期:2002-02-01 00:00:00
abstract:PURPOSE:To estimate the outpatient clinic burden and surgical workload related to glaucoma in Lagos, Nigeria. METHODS:A multicentre study involving the 2 tertiary eye institutions, 7 secondary eye centers with eye care facilities, and the largest private eye hospital in Lagos state, Nigeria. Data on outpatient departm...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究
doi:10.1097/IJG.0b013e318264cd80
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To assess the ability of frequency-doubling technology (FDT) perimetry and short-wavelength automated perimetry (SWAP) to detect glaucomatous damage in preperimetric glaucoma subjects. PARTICIPANTS:Two hundred seventy-eight eyes of 278 subjects categorized as normal eyes [n=98; intraocular pressure <20 mm Hg, ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31803bbb17
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To evaluate and compare the findings and changes of the anterior chamber angle configuration with indentation ultrasound biomicroscopy (UBM) gonioscopy in relative pupillary block (RPB), peripheral anterior synechia (PAS), and plateau iris configuration (PIC). METHODS:This study included 73 eyes of 52 patients...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000141366.45974.3a
更新日期:2004-12-01 00:00:00
abstract::Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patients' health decisions begin even before conception and continue throughout pregnancy and breastfeeding. The data on this topic is limited due to ethical and legal constraints and challenges of conducting large,...
journal_title:Journal of glaucoma
pub_type: 杂志文章,评审
doi:10.1097/IJG.0000000000001324
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:Upper eyelid sulcus deepening has recently been reported as an adverse effect of prostaglandin (PG) eye drop use. However, no data are available regarding the frequency of upper eyelid sulcus deepening caused by different types of PG eye drops. We used 5 types of PG eye drops in Japanese subjects and examined t...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31824d8d7c
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:Scarce data are available on the symmetry of 24-hour intraocular pressure (IOP) variations between fellow eyes of glaucoma patients, and such evidence could have profound consequences on the interpretation of monocular therapeutic trials. The objective is to evaluate the intereye correlation of continuously mea...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001563
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:To investigate the meibomian gland (MG) performance in patients with glaucoma under topical intraocular pressure (IOP)-lowering medications. MATERIALS AND METHODS:This was a cross-sectional case-control study. Patients with glaucoma under different dosages and instillation periods of topical IOP-lowering medic...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000841
更新日期:2018-02-01 00:00:00
abstract:PURPOSE:To investigate corneal viscoelasticity in primary open-angle glaucoma patients with and without diabetes mellitus, and to correlate corneal hysteresis (CH) with central corneal thickness (CCT). METHODS:In this cross-sectional study, 44 primary open-angle glaucoma patients [19 with diabetes (34 eyes) and 25 wit...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181b4caa1
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:The goal of this study was to identify the early postoperative intraocular pressure (IOP) that predicts low pressure control after a trabeculectomy with mitomycin C. MATERIALS AND METHODS:This study retrospectively analyzed the medical records of the initial trabeculectomy with mitomycin C in patients with pri...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e318285fd7d
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:To investigate the relationship between the peripapillary retinal nerve fiber layer (RNFL) thickness, as measured by Stratus time domain optical coherence tomography (OCT) (Stratus OCT) and Cirrus spectral domain OCT (Cirrus HD-OCT), and the severity indices of the visual field (VF) defects in glaucoma patients...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181efb371
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:To measure the serum bile acids (SBA) in patients with primary open-angle glaucoma (POAG) and to compare with nonglaucomatous controls. PATIENTS AND METHODS:A hospital-based case control study of 90 patients above the age of 40 years was conducted. Patients with POAG formed the study group and individuals with...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000993
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:To investigate the effects of topical instillation of 0.5% tranilast eye drops on intraocular pressure (IOP) and bleb formation after glaucoma filtering surgery. PATIENTS AND METHODS:This was a prospective, randomized, double-masked, and controlled clinical trial. A total of 52 eyes of 52 patients were randoml...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00061198-200204000-00008
更新日期:2002-04-01 00:00:00
abstract:PURPOSE:The pattern of the distribution of nerve fiber layer (NFL) thickness values across the retina may provide an early anatomic indication of glaucomatous disruption. We developed a method of analyzing polarimetry measurements that emphasizes the shape of the pattern of NFL thickness values. Sensitivity and specifi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200012000-00005
更新日期:2000-12-01 00:00:00
abstract:PURPOSE:To investigate levels of vascular endothelial growth factor (VEGF) and nitric oxide (NO) in the aqueous humor and plasma of patients with pseudoexfoliation syndrome (PXS) and pseudoexfoliation glaucoma (PXG), compared with controls. METHODS:This prospective study involved 37 patients with PXS, 15 with PXG, and...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181aae93e
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To evaluate circulatory melatonin levels by assessing nocturnal urinary excretion of 6-sulfatoxymelatonin (aMT6s) in patients with primary open-angle glaucoma (POAG) and to compare the high-tension group and the low-tension group. METHODS:This study included 80 eyes of 41 POAG patients and 87 eyes of 44 contro...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001130
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To determine if there is a difference in response of the adrenal gland to intramuscular adrenocorticotropic hormone (ACTH) between normals and ocular hypertensives (OHs) plus primary open-angle glaucomas (POAGs) without pigmented angles. METHODS:Intramuscular ACTH was given to 29 normals and 24 OH plus POAG ho...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3180334ff6
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To describe findings and utility of optical coherence tomography angiography (OCTA) in optic nerve head drusen (ONHD). OBSERVATIONS:A 57-year-old white man presented with a decrease in contrast sensitivity of the inferior visual field in both eyes. Clinical examination, visual fields, optical coherence tomogra...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000730
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:To determine the long-term intraocular pressure (IOP) control and postoperative complications after initial trabeculectomy with use of mitomycin C (MMC) in patients with primary open-angle glaucoma (POAG). PATIENTS AND METHODS:A retrospective review was conducted of a consecutive series of 123 eyes (87 patient...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000212202.57029.45
更新日期:2006-06-01 00:00:00
abstract:PURPOSE:The purpose of the study was to evaluate the tolerability and functionality of a wireless ocular telemetry sensor in African American patients with glaucoma. MATERIALS AND METHODS:In this prospective, observational cohort study, 20 African American patients with primary open angle glaucoma (POAG) were evaluate...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001141
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To study the frequencies and factors associated with 4 disc patterns in primary open-angle glaucoma (POAG) identified in population-based studies: focal glaucomatous (FG type), generalized enlargement of cup (GE type), myopic glaucomatous (MG type), and senile sclerotic glaucomatous (SS type) patterns. SUBJECT...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001240
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of transconjunctival revision (TCR) with mitomycin-C (MMC) following failed trabeculectomy. MATERIALS AND METHODS:The medical records of 27 patients (27 eyes) who underwent TCR with subconjunctival injection of MMC by a single surgeon between September 2001 and August 2013 were retrosp...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000408
更新日期:2016-07-01 00:00:00
abstract:PURPOSE:To evaluate the incidence of glaucoma and elevation of intraocular pressure (IOP) in patients with inflammatory eye disease. METHODS:Retrospective review of medical records of 391 consecutive patients with uveitis attending a uveitis clinic of an academic Department of Ophthalmology from January 1999 to August...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000146391.77618.d0
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:The aim of this study was to improve the scanning peripheral anterior chamber depth analyzer (SPAC) for measuring anterior chamber depth (ACD), differentiating eyes with shallow anterior chamber, and automatically categorizing eyes into subgroups based on the ACD values. We also investigated its accuracy for me...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000212256.25573.44
更新日期:2006-10-01 00:00:00
abstract:PURPOSE:To compare the efficacy and tolerability of latanoprost or brimonidine in patients with elevated intraocular pressure (IOP). MATERIALS AND METHODS:This prospective, randomized, masked-evaluator, parallel-group, multicenter study in the United States included patients with primary open angle glaucoma or ocular ...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/01.ijg.0000151881.99607.4e
更新日期:2005-04-01 00:00:00
abstract::PRéCIS:: In this study, we report clinical results after implantation of an adjustable glaucoma drainage device. The intraocular pressure (IOP) profile was efficiently controlled postoperatively as the resistance to aqueous humor outflow was finely adjusted. PURPOSE:The main purpose of this study was to evaluate the ...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/IJG.0000000000001209
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to examine the long-term efficacy and safety of dorzolamide (a topical carbonic anhydrase inhibitor, previously known as MK-507) as an ocular hypotensive agent. METHODS:This open-labeled, multicenter, 52-week trial enrolled patients with primary open-angle glaucoma or ocular hyper...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1995-02-01 00:00:00