Abstract：
AIMS:An observational study to determine the safety and efficacy of filtering surgery employing a microlumen aqueous drainage device (InnFocus MicroShunt), used intraoperatively with Mitomycin C, implanted alone or in combination with phacoemulsification. MATERIALS AND METHODS:Single-site, prospective, nonrandomized study of 23 eyes that had failed maximum tolerated glaucoma medication, followed for 3 years. A MicroShunt was implanted ab externo through a needle tract under the limbus, draining aqueous from the anterior chamber to the scleral surface. Prespecified outcome measures include: intraocular pressure (IOP) control, with and without supplemental medication, success rate, medication use, and adverse events. RESULTS:Fourteen patients received the MicroShunt alone and 9 with cataract surgery. At 1 (n=23), 2 (n=22), and 3 (n=22) years of follow-up; the qualified success rate (IOP ≤ 14 mm Hg and IOP reduction ≥ 20%) was 100%, 91%, and 95%; mean medicated IOP was reduced from 23.8 ± 5.3 to 10.7 ± 2.8, 11.9 ± 3.7, and 10.7 ± 3.5 mm Hg, and the mean number of glaucoma medications/patient was reduced from 2.4 ± 0.9 to 0.3 ± 0.8, 0.4 ± 1.0, and 0.7 ± 1.1, respectively. The most common complications were transient hypotony (13%, 3/23) and transient choroidal effusion (8.7%, 2/23), all resolved spontaneously. There were no leaks, infections, migrations, erosions, persistent corneal edema, or serious long-term adverse events. CONCLUSION:Surgery with the InnFocus MicroShunt transscleral aqueous drainage tube with Mitomycin C achieved IOP control in the low teens in most subjects up to 3 years of follow-up with only transient adverse events occurring within the first 3 months after surgery.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Batlle JF,Fantes F,Riss I,Pinchuk L,Alburquerque R,Kato YP,Arrieta E,Peralta AC,Palmberg P,Parrish RK 2nd,Weber BA,Parel JMdoi
10.1097/IJG.0000000000000368subject
Has Abstractpub_date
2016-02-01 00:00:00pages
e58-65issue
2eissn
1057-0829issn
1536-481Xjournal_volume
25pub_type
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journal_title：Journal of glaucoma
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journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2013-12-01 00:00:00
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journal_title：Journal of glaucoma
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更新日期：1995-08-01 00:00:00
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journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2003-06-01 00:00:00
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journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1998-12-01 00:00:00
abstract：:Many of these techniques have been adapted to investigate hemodynamic alterations, not only in glaucoma, but in diverse disorders such as diabetic retinopathy, macular degeneration, retinal dystrophies, and nonglaucomatous optic neuropathies. However, each of these techniques has limitations and there is not a single ...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/00061198-200110001-00022
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journal_title：Journal of glaucoma
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doi：10.1097/00061198-200604000-00013
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journal_title：Journal of glaucoma
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doi：
更新日期：1997-08-01 00:00:00
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更新日期：2008-01-01 00:00:00
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journal_title：Journal of glaucoma
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更新日期：2004-12-01 00:00:00
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journal_title：Journal of glaucoma
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更新日期：2020-07-01 00:00:00
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更新日期：2001-06-01 00:00:00
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更新日期：2016-04-01 00:00:00
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journal_title：Journal of glaucoma
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更新日期：2016-03-01 00:00:00
abstract：:The in vivo response to laser trabeculoplasty (LTP) was evaluated by measuring the incorporation of thymidine into DNA in the nuclei of trabecular meshwork cells. incorporation into DNA was analyzed by light microscopic autoradiography and by scintillation counting of trabecular extracts. Sixteen cats received argon L...
journal_title：Journal of glaucoma
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更新日期：1994-04-01 00:00:00
abstract：PURPOSE:To describe a new and simple technique of glaucoma tube extension that carries several advantages over previously described techniques. PATIENTS AND METHODS:A retrospective noncomparative case series of 3 patients (1 adult and 2 pediatric cases) with glaucoma tube retraction managed by the "tube-in-tube" techn...
journal_title：Journal of glaucoma
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更新日期：2017-02-01 00:00:00
