Expression and regulation of LOXL1 and elastin-related genes in eyes with exfoliation syndrome.

abstract：PURPOSE OF THE STUDY:The purpose of the study was to evaluate the long-term effectiveness and safety profile of Baerveldt glaucoma implant (BGI) in patients with refractory glaucoma operated using a modified technique to avoid postoperative complications. PATIENTS AND METHODS:A total of 160 eyes from 147 glaucomatous ...

journal_title：Journal of glaucoma

authors： Marchini G,Ceruti P,Vizzari G,Toscani M,Amantea C,Tosi R,Marchetti P

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To develop a descriptive system for a glaucoma-specific preference-based health-related quality of life (HRQoL) instrument: the Health Utility for Glaucoma (HUG-5). METHODS:The descriptive system was developed in 2 stages: item identification and item selection. A systematic literature review of HRQoL assessme...

journal_title：Journal of glaucoma

authors： Muratov S,Podbielski DW,Kennedy K,Jack SM,Pemberton J,Ahmed IIK,Baltaziak M,Xie F

更新日期：2018-07-01 00:00:00

abstract：:The multifunctional protein clusterin (CLU) is a secreted glycoprotein ubiquitously expressed throughout the body, including in the eye. Its primary function is to act as an extracellular molecular chaperone, preventing the precipitation and aggregation of misfolded extracellular proteins. Clusterin is commonly identi...

journal_title：Journal of glaucoma

authors： Wiggs JL,Kang JH,Fan B,Levkovitch-Verbin H,Pasquale LR

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To determine if laser iridotomy altered the anterior segment anatomy of patients with plateau iris configuration. METHODS:Twenty eyes of 9 female and 1 male patients were imaged using an ultrasound biomicroscope within 19 weeks before and 52 weeks after laser iridotomy. Measurements obtained included the anter...

journal_title：Journal of glaucoma

authors： Polikoff LA,Chanis RA,Toor A,Ramos-Esteban JC,Fahim MM,Gagliuso DJ,Serle JB

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:To evaluate the diagnostic ability of macular parameters and peripapillary retinal nerve fiber layer (RNFL) parameters for early glaucoma using spectral domain optical coherence tomography (SD-OCT). MATERIALS AND METHODS:One eye from 32 early glaucoma patients (including preperimetric glaucoma) and 32 normal p...

journal_title：Journal of glaucoma

authors： Nakatani Y,Higashide T,Ohkubo S,Takeda H,Sugiyama K

更新日期：2011-04-01 00:00:00

abstract：PURPOSE:The authors describe the first case of delayed antimetabolite-related corneal epithelial toxicity after trabeculectomy and its successful treatment with limbal stem cell transplantation. METHODS:A 73-year-old woman underwent trabeculectomy with intraoperative mitomycin C. After surgery she received six 5-mg in...

journal_title：Journal of glaucoma

authors： Manche EE,Afshari MA,Singh K

更新日期：1998-08-01 00:00:00

abstract：PRECIS:Citicoline eyedrops in patients with progressing glaucoma. PURPOSE:This study aimed to test whether the additional therapy with citicoline eyedrops to intraocular pressure (IOP)-lowering treatment could slow glaucoma progression in patients with worsening of damage and IOP 18 mm Hg or less. DESIGN:This was a r...

journal_title：Journal of glaucoma

authors： Rossetti L,Iester M,Tranchina L,Ottobelli L,Coco G,Calcatelli E,Ancona C,Cirafici P,Manni G

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:The purpose of this article was to report the efficacy of intravitreal bevacizumab to resolve secondary angle-closure glaucoma caused by biliary tract carcinoma metastasis to the iris. MATERIALS AND METHODS:A 52-year-old white woman who was under systemic chemotherapy for biliary tract carcinoma presented with...

journal_title：Journal of glaucoma

authors： Aydin R,Tezel TH

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:This study aimed to investigate (1) the prevalence of nonadherence with eye drop treatment; (2) selected correlates of nonadherence at the patient and health-care organization level; and (3) the diagnostic value of the ophthalmologists' ratings, using patients' self-reports as standard. METHODS:This cross-sect...

journal_title：Journal of glaucoma

authors： Vandenbroeck S,De Geest S,Dobbels F,Fieuws S,Stalmans I,Zeyen T

更新日期：2011-09-01 00:00:00

abstract：PURPOSE:The purpose of the study was to evaluate the tolerability and functionality of a wireless ocular telemetry sensor in African American patients with glaucoma. MATERIALS AND METHODS:In this prospective, observational cohort study, 20 African American patients with primary open angle glaucoma (POAG) were evaluate...

journal_title：Journal of glaucoma

authors： Marando CM,Mansouri K,Kahook MY,Seibold LK

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:To propose a new surgical technique for optimized visualization of the chamber angle using scleral indentation under an operating microscope in goniosynechialysis (GSL). PATIENTS AND METHODS:Six volunteers with normal chamber angle and five patients with synechial angle closure glaucoma were examined. Scleral ...

journal_title：Journal of glaucoma

authors： Takanashi T,Masuda H,Tanito M,Nonoyama S,Katsube T,Ohira A

更新日期：2005-08-01 00:00:00

abstract：STUDY OBJECTIVES:The association between obstructive sleep apnea syndrome (OSAS) and retinal nerve fiber layer (RNFL) thickness has been examined in many studies. However, the findings are inconsistent. Our goal is to evaluate the association between OSAS and RNFL thickness by performing a meta-analysis. METHODS:We co...

journal_title：Journal of glaucoma

authors： Zhao XJ,Yang CC,Zhang JC,Zheng H,Liu PP,Li Q

更新日期：2016-04-01 00:00:00

abstract：PURPOSE:Primary open-angle glaucoma is a significant health-economic burden in both the United States and Europe that is likely to increase. This study compared treatment patterns and cost among patients with primary open-angle glaucoma in these locations. METHODS:Retrospective medical chart reviews were conducted in ...

journal_title：Journal of glaucoma

authors： Lee PP,Kelly SP,Mills RP,Traverso CE,Walt JG,Doyle JJ,Katz LM,Siegartel LR,Costs of Glaucoma Study Group.

更新日期：2007-08-01 00:00:00

abstract：PURPOSE:To investigate, using in vivo confocal microscopy (IVCM), the Meibomian gland (MG) features and conjunctival goblet cell density (GCD) in glaucomatous patients controlled with prostaglandin/timolol fixed combinations (PTFCs). MATERIALS AND METHODS:In this cross-sectional study, 60 white patients were treated w...

journal_title：Journal of glaucoma

authors： Agnifili L,Mastropasqua R,Fasanella V,Brescia L,Scatena B,Oddone F,Mastropasqua L

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:To compare the efficacy and tolerability of latanoprost or brimonidine in patients with elevated intraocular pressure (IOP). MATERIALS AND METHODS:This prospective, randomized, masked-evaluator, parallel-group, multicenter study in the United States included patients with primary open angle glaucoma or ocular ...

journal_title：Journal of glaucoma

authors： Camras CB,Sheu WP,United States Latanoprost-Brimonidine Study Group.

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:The purpose of this study was to examine the long-term efficacy and safety of dorzolamide (a topical carbonic anhydrase inhibitor, previously known as MK-507) as an ocular hypotensive agent. METHODS:This open-labeled, multicenter, 52-week trial enrolled patients with primary open-angle glaucoma or ocular hyper...

journal_title：Journal of glaucoma

authors： MK-507 Clinical Study Group.

更新日期：1995-02-01 00:00:00

abstract：PURPOSE:The authors quantitatively evaluate the kinetics of fluid transfer from microsurgical sponges in a laboratory model to understand the kinetics of mitomycin C (MMC) delivery. METHODS:The amount of fluid transferred from soaked methylcellulose (Weck-cel, Weck Inc., Durham, NC, U.S.A.) sponges to small pieces of ...

journal_title：Journal of glaucoma

authors： Brooks SE,Laird ML,Marcus DM,Johnson MH,Ramage JI,Green K

更新日期：1998-02-01 00:00:00

abstract：PURPOSE:The Molteno implant is one of the most widely used drainage devices for the management of complicated glaucoma. Antiproliferative agents such as mitomycin-C (MMC) have markedly improved the outcome of glaucoma filtering surgery. This case control study compares the results of these two techniques in the managem...

journal_title：Journal of glaucoma

authors： Sayyad FE,Helal M,Elsherif Z,El-Maghraby A

更新日期：1995-04-01 00:00:00

abstract：PURPOSE:To report plateau iris configuration (PIC) in subjects who have the long anterior zonule (LAZ) clinical trait. METHODS:Two elderly African American males who exhibited LAZ and had partial appositional angle closure persisting after laser iridotomy were imaged with high-resolution ultrasonography to examine for...

journal_title：Journal of glaucoma

authors： Roberts DK,Ayyagari R,Moroi SE

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To report 3-year results evaluating the effect on safety and efficacy of canaloplasty to treat open-angle glaucoma when combined with cataract surgery. PATIENTS AND METHODS:This was a retrospective subset analysis of a prospective, international, multicenter study evaluating 133 eyes of 133 adult, open-angle g...

journal_title：Journal of glaucoma

authors： Tetz M,Koerber N,Shingleton BJ,von Wolff K,Bull H,Samuelson TW,Lewis RA

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:To evaluate the neuroprotective effect of rasagiline (N-propargyl-1 (R)-aminoindan), a selective monoamine oxidase inhibitor, on the survival of retinal ganglion cells (RGCs) in glaucomatous rat eyes. Rasagiline is an FDA approved anti-Parkinson disease drug with neuroprotective capabilities that were shown in ...

journal_title：Journal of glaucoma

authors： Levkovitch-Verbin H,Vander S,Melamed S

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:To report the safety and the effectiveness of deep sclerectomy (DS) with a new nonabsorbable uveoscleral hema implant (Esnoper-Clip) designed to increase trabecular and uveoscleral outflow and to achieve higher intrascleral blebs. MATERIALS AND METHODS:Twenty-seven eyes of 27 patients with open-angle glaucoma,...

journal_title：Journal of glaucoma

authors： Loscos-Arenas J,Parera-Arranz A,Romera-Romera P,Castellvi-Manent J,Sabala-Llopart A,de la Cámara-Hermoso J

更新日期：2015-08-01 00:00:00

abstract：PRECIS:Repeated use of the Micropulse P3 (MP3) probe during micropulse transscleral cyclophotocoagulation is associated with an increase in laser output over time. PURPOSE:The purpose of this study was to examine the laser efficacy of the MP3 probe following repeated use. METHODS:This was an observational study carri...

journal_title：Journal of glaucoma

authors： Lun K,Suwandono ME,Koh V,Chew PT

更新日期：2019-08-01 00:00:00

abstract：PURPOSE:To investigate the association of antihypertensive medications with optic disc structure by blood pressure (BP) level, in nonglaucoma subjects. DESIGN:Cross-sectional, population-based study. METHODS:A subset of Thessaloniki Eye Study participants was included in this study. Subjects were interviewed for medi...

journal_title：Journal of glaucoma

authors： Harris A,Topouzis F,Wilson MR,Founti P,Kheradiya NS,Anastasopoulos E,Gong G,Yu F,Jonescu-Cuypers CP,Pappas T,Koskosas A,Coleman AL

更新日期：2013-09-01 00:00:00

abstract：PURPOSE:Evaluate the long-term results of the Ahmed glaucoma valve (AGV) surgery in association with bevacizumab (Avastin) in neovascular glaucoma (NVG) patients. DESIGN AND METHODS:This retrospective institutional study reviewed 39 eyes of 34 patients with NVG who underwent AGV implantation. The intravitreal bevacizu...

journal_title：Journal of glaucoma

authors： Sahyoun M,Azar G,Khoueir Z,Antoun J,Kourie H,Nehme J,Jalkh A

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To compare central corneal thickness between eyes with congenital glaucoma and normal controls and to correlate this parameter with corneal diameter and axial length. METHODS:Eyes of consecutive children with congenital glaucoma with previous glaucoma surgery and eyes of children with inadequacy of lacrimal dr...

journal_title：Journal of glaucoma

authors： Henriques MJ,Vessani RM,Reis FA,de Almeida GV,Betinjane AJ,Susanna R Jr

更新日期：2004-06-01 00:00:00

abstract：PURPOSE:To compare the rates of retinal nerve fiber layer (RNFL) thickness loss using optical coherence tomography (OCT) in progressing versus nonprogressing eyes using 4 methods to define functional progression. METHODS:Normal and glaucomatous eyes with ≥3 years of follow up were prospectively enrolled. Standard auto...

journal_title：Journal of glaucoma

authors： Grewal DS,Sehi M,Paauw JD,Greenfield DS,Advanced Imaging in Glaucoma Study Group.

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:To investigate changes in scanning laser polarimetry with variable corneal compensation (GDx-VCC) parameters caused by posterior capsular opacification (PCO). METHODS:In this comparative case-control series, 20 eyes due to undergo YAG laser capsulotomy for PCO were recruited. GDx-VCC was performed before and a...

journal_title：Journal of glaucoma

authors： Brittain CJ,Fong KC,Hull CC,Gillespie IH

更新日期：2007-01-01 00:00:00

abstract：PURPOSE:To investigate the meibomian gland (MG) performance in patients with glaucoma under topical intraocular pressure (IOP)-lowering medications. MATERIALS AND METHODS:This was a cross-sectional case-control study. Patients with glaucoma under different dosages and instillation periods of topical IOP-lowering medic...

journal_title：Journal of glaucoma

authors： Cho WH,Lai IC,Fang PC,Chien CC,Tseng SL,Lai YH,Huang YT,Kuo MT

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:The objective was to assess the long-term economic consequences of the medical management of glaucoma in the UK. METHODS:The economic evaluation was conducted using the results from a 10-year Markov model based around 3 key triggers for a switch in medical therapy for glaucoma, namely: lack of tolerance (using...

journal_title：Journal of glaucoma

authors： Orme M,Collins S,Loftus J

更新日期：2012-09-01 00:00:00