Abstract：
PURPOSE:To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) in primary and pseudoexfoliative open-angle glaucoma. MATERIALS AND METHODS:Patients for primary filtration surgery underwent CLASS with a CO2 laser system (OT-134-IOPtiMate, IOPtima Ltd., Ramat Gan, Israel). This self-controlled system gradually ablates and removes scleral layers until percolating fluid absorbs the energy, attenuating further tissue ablation. Intraocular pressure (IOP) was measured at baseline, 1, 2, 4, and 6 weeks, and 3, 6, and 12 months, respectively. Complete success was defined as 5≤IOP≤18 mm Hg and 20% IOP reduction with no medication at a 12-month endpoint visit, and qualified success as the same IOP range with or without medication. RESULTS:Thirty of 37 patients completed 12 months of follow-up. Mitomycin C was used in 25 procedures (83.3%). The mean baseline IOP of 26.3±7.8 mm Hg (mean±SD) dropped to 14.4±3.4 and 14.3±3.1 mm Hg at 6 and 12 months, respectively, with 42.4% and 40.7% IOP reduction at 6 and 12 months, respectively (P<0.001). Complete success was achieved by 76.7% and 60% of the patients at 6 and 12 months, respectively, whereas qualified success was achieved by 83.3% and 86.6% of the patients at 6 and 12 months, respectively. Complications were mild and transitory with no sequela. CONCLUSIONS:Short-term and intermediate results suggest that CLASS may become a simple, safe, and effective means of choice for the treatment of open-angle glaucoma.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Geffen N,Ton Y,Degani J,Assia EIdoi
10.1097/IJG.0b013e3181f7b14fsubject
Has Abstractpub_date
2012-03-01 00:00:00pages
193-8issue
3eissn
1057-0829issn
1536-481Xjournal_volume
21pub_type
临床试验,杂志文章,多中心研究abstract：PURPOSE:To determine the effect of cataract extraction on the glaucoma progression index (GPI) in glaucoma patients with coexisting cataract. PATIENTS AND METHODS:This is a retrospective noncomparative study. Consecutive eligible patients with glaucoma who underwent phacoemulsification alone or in combination with aug...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181b21fb9
更新日期：2010-04-01 00:00:00
abstract：PURPOSE:To evaluate the influence of age-related macular degeneration (AMD) on macular thickness measurement made with Fourier-domain optical coherence tomography (RTVue-OCT) to detect glaucoma. METHODS:: One nonglaucomatous eye of 79 white persons was imaged. This comprised 25 healthy eyes, 19 eyes with early/interme...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31824083e6
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:To investigate the agreement between neuroretinal rim area (RA) measurements using the Heidelberg Retina Tomograph I (HRT Classic) and Heidelberg Retina Tomograph II (HRT II). To compare apparent RA changes in follow-up series of HRT II topographies when using either an HRT Classic or HRT II mean topography as ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318255da30
更新日期：2013-10-01 00:00:00
abstract：:A 78-year-old man with angle closure glaucoma and on treatment with oral anticoagulants, underwent phacoemulsification. An early acute suprachoroidal hemorrhage (SCH) occurred and the surgical wound was rapidly sutured without complete soft lens matter removal, nor insertion of intraocular lens. The SCH was managed co...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001170
更新日期：2019-05-01 00:00:00
abstract：PURPOSE:To evaluate the effects of flunarizine, a nonselective calcium channel blocker, on intraocular pressure (IOP) in monkeys with laser-induced unilateral glaucoma and on aqueous humor dynamics in normal monkeys. METHODS:The IOP was measured before and hourly for 6 hours after single-dose administration of 0.5%, 1...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318133a845
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:To compare characteristics of functioning blebs (FBs) and nonfunctioning blebs (NFBs) with en-face spectral-domain optical coherence tomography (OCT). METHODS:We evaluated 41 blebs of 38 patients after a first-time trabeculectomy. Eyes were classified into 2 groups: FBs (22 eyes) and NFBs (19 eyes). En-face OC...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000319
更新日期：2016-05-01 00:00:00
abstract：:We report a case of an explanted stainless steel miniature glaucoma drainage device (EX-PRESS) implanted under a scleral flap for pseudoexfoliation open-angle glaucoma surgical treatment. The glaucoma shunt was implanted in a 75-year-old white man with medically refractive glaucoma. Cataract surgery was performed simu...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000521
更新日期：2017-01-01 00:00:00
abstract：PURPOSE:To investigate changes in scanning laser polarimetry with variable corneal compensation (GDx-VCC) parameters caused by posterior capsular opacification (PCO). METHODS:In this comparative case-control series, 20 eyes due to undergo YAG laser capsulotomy for PCO were recruited. GDx-VCC was performed before and a...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000243469.05719.0d
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:To investigate the relationship between retinal nerve fiber layer (RNFL) measurements in corresponding areas obtained with scanning laser polarimetry and optical coherence tomography and to compare their discriminating ability in the diagnosis of preperimetric and perimetric glaucoma. PATIENTS AND METHODS:Thre...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181a2fc0e
更新日期：2010-02-01 00:00:00
abstract：:Treatment with noncardioselective beta-adrenoceptor antagonists (e.g., 0.5% timolol or 0.5% levobunolol) is standard practice for lowering elevated intraocular pressure (IOP). However, because there are risks and side effects associated with the use of these agents, a lower, yet still effective, dose may be preferred....
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-199201040-00005
更新日期：1992-01-01 00:00:00
abstract：PURPOSE:The aim of the study was to investigate whether floppy eyelid syndrome (FES) could be an indicator of glaucoma in patients with obstructive sleep apnea (OSA). MATERIALS AND METHODS:A total of 152 patients were included: 75 patients with OSA and without FES; 52 patients with OSA and FES; and 25 non-OSA patients...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31829da19f
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:To evaluate an alternate method of covering the subconjunctival portion of the tube in aqueous shunt surgery. Evidence of tube erosion, graft-related infection, graft melting, or other associated intraocular complications were evaluated. METHODS:A retrospective study of 16 patients (17 eyes) who underwent tube...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：AIM:Dietary deficiencies in ω-3 polyunsaturated fatty acids are known to effect retinal function including retinal ganglion cell (RGC) activity, which may have implications for glaucoma. In this study we consider retinal function after dietary manipulation and intraocular pressure (IOP) stress designed to compromise RG...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318237cac7
更新日期：2013-04-01 00:00:00
abstract：PURPOSE:The aim of this study is to evaluate the safety and efficacy of laser goniopuncture (LGP) to lower intraocular pressure (IOP) post-viscocanalostomy (VC)/phacoviscocanalostomy (PVC). Outcomes include: IOP reduction from pre-LGP levels and the need for further topical antiglaucomatous medication or surgery. PATI...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000333
更新日期：2016-06-01 00:00:00
abstract：PURPOSE:To evaluate the safety and efficacy of Ahmed Glaucoma Valve implantation (AGVI) for the management of neovascular glaucoma (NVG) associated with proliferative diabetic retinopathy (PDR) in the vitrectomized eyes. PATIENTS AND METHODS:We reviewed the medical records of patients with NVG associated with PDR who ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181f3eb06
更新日期：2011-09-01 00:00:00
abstract：AIMS:An observational study to determine the safety and efficacy of filtering surgery employing a microlumen aqueous drainage device (InnFocus MicroShunt), used intraoperatively with Mitomycin C, implanted alone or in combination with phacoemulsification. MATERIALS AND METHODS:Single-site, prospective, nonrandomized s...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000368
更新日期：2016-02-01 00:00:00
abstract：PURPOSE:More than one million patients in the United States are treated for glaucoma, although little is known about the typical clinical characteristics of this group of patients and the type of therapy they receive. This study was conducted to describe the demographic and diagnostic characteristics of patients beginn...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200002000-00008
更新日期：2000-02-01 00:00:00
abstract：:Exfoliation syndrome (XFS) is considered to be a disease of extracellular matrix. Here we review key experimental evidence of aberrations in structure, expression, and function of glycoproteins, complex carbohydrates, and glycosaminoglycans found in extracellular matrix components forming exfoliation material in patie...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0000000000000118
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:The authors describe the first case of delayed antimetabolite-related corneal epithelial toxicity after trabeculectomy and its successful treatment with limbal stem cell transplantation. METHODS:A 73-year-old woman underwent trabeculectomy with intraoperative mitomycin C. After surgery she received six 5-mg in...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：PURPOSE:To evaluate the peripapillary retinal nerve fiber layer (RNFL), ganglion cell complex, and macular thickness as well as their correlation with the severity of diseases. MATERIALS AND METHODS:This is a cross-sectional study and comparing both eyes of 26 patients with primary open-angle glaucoma, 25 patients wit...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000239
更新日期：2016-07-01 00:00:00
abstract：PURPOSE:To evaluate rates of adherence to free follow-up eye exam appointments among participants in the Philadelphia Glaucoma Detection and Treatment Project. PATIENTS AND METHODS:Ophthalmologists and testing equipment were brought directly to participants at risk for glaucoma at 43 community sites in Philadelphia. T...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/IJG.0000000000000716
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:The purpose of this study was to compare early postoperative outcomes of patients who underwent Baerveldt 350-mm aqueous drainage device (Abbott Medical Optics Inc., Santa Ana, CA) implantation with and without 7-0 polyglactin (vicryl) suture placement through tube fenestration to serve as a stenting wick. MET...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001080
更新日期：2018-12-01 00:00:00
abstract：AIMS:To compare the retinal nerve fiber layer thickness (RNFLT) parameters obtained with newly introduced GDx with enhanced corneal compensation (ECC) and those with GDx with variable corneal compensation (VCC) and to evaluate their reproducibility and the correspondence with visual field damage (VFD) in total or secto...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318133fb47
更新日期：2008-01-01 00:00:00
abstract：:The multifunctional protein clusterin (CLU) is a secreted glycoprotein ubiquitously expressed throughout the body, including in the eye. Its primary function is to act as an extracellular molecular chaperone, preventing the precipitation and aggregation of misfolded extracellular proteins. Clusterin is commonly identi...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0000000000000916
更新日期：2018-07-01 00:00:00
abstract：:We determined the results of routine whole-field scotopic vision testing in consecutive patients with ocular hypertension or glaucoma who underwent Humphrey automated perimetric testing and optic disc examination. In 39 ocular hypertensive patients we found a mean threshold of 16.7 +/- 7.4 dB and in 61 glaucoma patien...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:To determine if laser iridotomy altered the anterior segment anatomy of patients with plateau iris configuration. METHODS:Twenty eyes of 9 female and 1 male patients were imaged using an ultrasound biomicroscope within 19 weeks before and 52 weeks after laser iridotomy. Measurements obtained included the anter...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000151687.96785.03
更新日期：2005-04-01 00:00:00
abstract：PURPOSE:To evaluate the effectiveness of using a noncontact tonometer (NCT) versus a rebound tonometer (ICare) when measuring the intraocular pressure (IOP) in healthy children. DESIGN:Prospective observational study. METHODS:A total of 180 (96 males and 84 females) healthy children, aged 6 months to 15 years, were r...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181d12dc4
更新日期：2011-01-01 00:00:00
abstract：PURPOSE:The GDx is a scanning laser polarimeter that assesses peripapillary nerve fiber layer thickness. In addition to the 14 existing outcome parameters, four new parameters have been described recently: the Ellipse Standard Deviation (ESD), the Normalized Superior Area (NSA), the Normalized Inferior Area (NIA) and t...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200402000-00006
更新日期：2004-02-01 00:00:00
abstract：:The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address known complications of conventional filtering surgery. They are, ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001417
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:To compare the efficacy, safety, and long-term results of intraocular pressure (IOP) reduction by diode laser contact cyclophotocoagulation (DCPC) and Ahmed glaucoma valve (AGV) implant in cases of neovascular glaucoma. METHODS:A total of 66 eyes of 66 patients with neovascular glaucoma were prospectively a...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31817d235c
更新日期：2009-03-01 00:00:00
