Abstract：
PURPOSE:To evaluate the results of Ahmed Glaucoma Valve surgery in neovascular glaucoma and control patients. PATIENTS AND METHODS:In this retrospective comparative study, we reviewed 76 eyes of 76 patients, comparing the surgical outcomes in control patients (N=38) to matched neovascular glaucoma patients (N=38). Success was defined as intraocular pressure (IOP) ≥6 mm Hg and ≤21 mm Hg, without further glaucoma surgery, and without loss of light perception. RESULTS:Average follow-up for control and neovascular glaucoma patients was 18.4 and 17.4 months, respectively (P=0.550). The mean IOPs were 17.9±8.4 mm Hg and 16.5±15.8 mm Hg at 1-year (P=0.150), and 18.4±11.2 mm Hg and 9.9±6.3 mm Hg at 2 years (P=0.057) in controls and eyes with neovascular glaucoma, respectively. Life-table analysis showed a significantly lower success for neovascular glaucoma patients compared with controls (P=0.0096), with success at 1 year=89.2% and 73.1%, 2 years=81.8% and 61.9%, and 5 years=81.8% and 20.6% for control and neovascular glaucoma eyes, respectively. Cox proportional hazard regression analysis showed neovascular glaucoma as a risk factor for surgical failure (odds ratio=5.384, 95% CI=1.22-23.84, P=0.027). Although IOP control and complications were comparable between the 2 groups, visual outcomes were worse in neovascular glaucoma patients, with 9 (23.7%) eyes with neovascular glaucoma compared with no controls losing light perception vision (P=0.002). The majority with loss of vision (5 of 9) had successful control of IOP during the postoperative period. CONCLUSIONS:Neovascular glaucoma patients have greater risk of surgical failure after Ahmed Glaucoma Valve surgery compared with controls. Despite improved IOP with drainage implants, visual outcomes may be poor, probably owing to progression of underlying disease.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Netland PA,Ishida K,Boyle JWdoi
10.1097/IJG.0b013e3181ca7f7fsubject
Has Abstractpub_date
2010-12-01 00:00:00pages
581-6issue
9eissn
1057-0829issn
1536-481Xjournal_volume
19pub_type
杂志文章abstract：OBJECTIVES:To evaluate the outcomes of trabeculectomy with mitomycin-C (MMC) in uveitis associated with Vogt-Koyanagi-Harada disease (VKH). METHODS:Retrospective cohort study included 27 eyes of 15 patients with uveitic glaucoma associated with VKH disease who underwent trabeculectomy with MMC as a first glaucoma proc...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000384
更新日期：2016-06-01 00:00:00
abstract：PURPOSE:To assess the efficacy and safety of botulinum toxin type A (BoNT-A) injection in patients suffering from intractable periorbital pain after acute angle closure glaucoma (AACG). PATIENTS AND METHODS:In this prospective randomized intervention study, 19 patients suffering from periorbital pain after an AACG att...
journal_title：Journal of glaucoma
pub_type： 杂志文章,随机对照试验
doi：10.1097/IJG.0b013e3181ca76a9
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To characterize and compare the ocular comfort and symptoms of dorzolamide and tear-replacement drops (placebo) in healthy volunteers. PATIENTS AND METHODS:Subjects were randomized in a double-masked fashion to receive each medicine for 6 days twice daily. Patients used a visual analog scale to assess the qual...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200304000-00010
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:The aim of this study was to quantitatively study the retinal nerve fiber layer (RNFL) thickness in children born prematurely with isolated optic nerve cupping. PATIENTS AND METHODS:Six otherwise healthy premature children with clinical evidence of increased cup to disc ratios were enrolled in this observation...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000006
更新日期：2014-01-01 00:00:00
abstract：PRECIS:Repeated use of the Micropulse P3 (MP3) probe during micropulse transscleral cyclophotocoagulation is associated with an increase in laser output over time. PURPOSE:The purpose of this study was to examine the laser efficacy of the MP3 probe following repeated use. METHODS:This was an observational study carri...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001277
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the factors that influence the outcome of trabectome surgery. METHODS:This was a retrospective nonrandomized study. Seventy-eight glaucoma patients (86 eyes) who underwent trabectome surgeries and were followed up for more than 12 months were included. We classified ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000743
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:To report clinical outcomes after pars plana endoscopic cyclophotocoagulation of the ciliary processes and pars plana (ECP-plus), a novel treatment for refractory glaucoma. DESIGN:Retrospective, noncomparative interventional case series. MATERIALS AND METHODS: SETTING:multicenter tertiary referral academic a...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/IJG.0000000000000278
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:To investigate levels of vascular endothelial growth factor (VEGF) and nitric oxide (NO) in the aqueous humor and plasma of patients with pseudoexfoliation syndrome (PXS) and pseudoexfoliation glaucoma (PXG), compared with controls. METHODS:This prospective study involved 37 patients with PXS, 15 with PXG, and...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181aae93e
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:To estimate resource use and costs associated with the diagnosis and treatment of glaucoma and ocular hypertension in the Netherlands in 1996 and to determine how costs differed between patients, diagnoses, and hospitals. PATIENTS AND METHODS:Patient characteristics and glaucoma-related resource use were colle...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200106000-00007
更新日期：2001-06-01 00:00:00
abstract：PURPOSE:To report the safety and the effectiveness of deep sclerectomy (DS) with a new nonabsorbable uveoscleral hema implant (Esnoper-Clip) designed to increase trabecular and uveoscleral outflow and to achieve higher intrascleral blebs. MATERIALS AND METHODS:Twenty-seven eyes of 27 patients with open-angle glaucoma,...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000253
更新日期：2015-08-01 00:00:00
abstract：PURPOSE:To assess the efficacy of collagen cross-linking in the treatment of late-onset bleb leakage. METHODS:A retrospective, interventional case-series. Cross-linking was performed for late-onset bleb leakage after failure of standard medical therapy. Primary outcome is measured by complete resolution of bleb leakag...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000295
更新日期：2016-03-01 00:00:00
abstract：PURPOSE:To evaluate the usefulness of day-long sequential office measurements of intraocular pressure (IOP) to make therapeutic decisions in patients with progressive glaucomatous damage despite apparently 'controlled' IOP. METHODS:We reviewed the records of 93 consecutive glaucoma patients (185 eyes) who underwent se...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000159125.34241.79
更新日期：2005-06-01 00:00:00
abstract：PURPOSE:To compare the results of frequency-doubling technology perimetry (FDT), assumed to test the magnocellular visual pathway, and high-pass resolution perimetry (HRP), assumed to test the parvocellular visual pathway, in patients with ocular hypertension or glaucoma. PATIENTS AND METHODS:Forty-eight consecutive p...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200302000-00008
更新日期：2003-02-01 00:00:00
abstract：PURPOSE:To determine the risk factors for hyphema after trabeculectomy with mitomycin C (MMC). PATIENTS AND METHODS:In total, 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto University Hospital, Japan, were retrospectively evaluated. Hy...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3182741c85
更新日期：2014-06-01 00:00:00
abstract：PURPOSE:We aimed to evaluate the ability of new psychophysical discrimination tests, based on readily available hardware, to probe motion, achromatic, and chromatic contrast sensitivity, across the natural history of glaucoma. We assessed the sensitivity of these tests to detect functional damage at ocular hypertension...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000226
更新日期：2016-06-01 00:00:00
abstract：PURPOSE:To assess the reproducibility of retinal nerve fiber layer thickness and macular thickness measurements using OCT-3. METHODS:Randomly chosen eyes of healthy individuals were scanned following pupillary dilation by two trained operators (RGO, RV) using OCT-3 (software version A1.1, Carl Zeiss Meditec, Inc., Dub...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200406000-00012
更新日期：2004-06-01 00:00:00
abstract：PURPOSE:Subconjunctival mitomycin C has been used in glaucoma filtration surgery with success. A prospective, randomized, masked, placebo-controlled study was performed to evaluate whether single transconjunctival mitomycin C applied either preoperatively or postoperatively would enhance the success of filtration surge...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：PURPOSE:To discuss a case in which melanocytoma of the ciliary body presented with widespread pigment dispersion and elevated intraocular pressure (IOP). METHODS:A 64-year old woman presented with increased IOP and persistent anterior segment inflammation in her right eye. She had undergone a trabeculectomy for uncont...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：PURPOSE:To examine the effect of the myopic optical defocus on the Humphrey Matrix 30-2 test. DESIGN:Prospective, nonrandomized, comparative case series. METHODS:Forty eyes from 40 patients with and without glaucoma underwent 2 consecutive tests using the Humphrey Matrix 30-2 threshold program. The first and second t...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181b21ef6
更新日期：2010-04-01 00:00:00
abstract：PRECIS:As the only microinvasive glaucoma surgery (MIGS) with a reusable component, the cost per procedure of endoscopic cyclophotocoagulation (ECP) diminishes with each successive use. We present a cost comparison of ECP with other MIGS devices, based on our clinical practice. PURPOSE:ECP delivers diode laser via a r...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001245
更新日期：2019-06-01 00:00:00
abstract：PURPOSE:To estimate the outpatient clinic burden and surgical workload related to glaucoma in Lagos, Nigeria. METHODS:A multicentre study involving the 2 tertiary eye institutions, 7 secondary eye centers with eye care facilities, and the largest private eye hospital in Lagos state, Nigeria. Data on outpatient departm...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/IJG.0b013e318264cd80
更新日期：2014-01-01 00:00:00
abstract：PRCIS:Use of toric intraocular lenses is a reasonable option for better visual outcomes when a combined minimally invasive glaucoma surgery (MIGS) and cataract surgery is performed in eyes with corneal astigmatism. PURPOSE:To assess the efficacy of toric intraocular lenses (IOLs) in combined cataract and MIGS, visual ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001705
更新日期：2021-01-01 00:00:00
abstract：PURPOSE:To describe a surgical technique to improve visualization and surgical access for trabeculectomy and implantation of aqueous drainage devices. MATERIALS AND METHODS:After the corneal traction suture (6-0 polygalactin; S-29 needle) is placed, a second suture is passed through Tenon's capsule alone, either at th...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200212000-00014
更新日期：2002-12-01 00:00:00
abstract：PURPOSE:To compare the results of Ahmed glaucoma valve (AGV) implantation in eyes containing silicone oil to those without silicone oil. METHODS:This was a multicenter, retrospective, comparative study of 94 eyes in 94 patients with mean follow-up of 2 years, comparing surgical outcomes in eyes with silicone oil (N=47...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318182ede3
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:To determine the outcomes of bleb excision with free autologous conjunctival patch grafting for bleb leak and hypotony after glaucoma filtering surgery. PATIENTS AND METHODS:Retrospective, consecutive, noncomparative case series. Outcome measures were closure of bleb leak, intraocular pressure (IOP), and best ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181e87efc
更新日期：2011-08-01 00:00:00
abstract：:A 56-year-old Hispanic male individual with moderate primary open-angle glaucoma on maximal tolerated topical therapy with recent visual field progression presented with excessive glare due to cataract in the right eye. The patient underwent uncomplicated phacoemulsification with supraciliary microstent implantation. ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001407
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to examine the long-term efficacy and safety of dorzolamide (a topical carbonic anhydrase inhibitor, previously known as MK-507) as an ocular hypotensive agent. METHODS:This open-labeled, multicenter, 52-week trial enrolled patients with primary open-angle glaucoma or ocular hyper...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1995-02-01 00:00:00
abstract：PURPOSE:To report a woman with congenital rubella syndrome of delayed-onset, bleb-related endophthalmitis induced by Streptococcus intermedius. METHODS:Interventional case report. RESULTS:A 33-year-old woman who underwent bilateral trabeculectomy with adjunctive mitomycin C, 11 years earlier presented with redness an...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318170a732
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE AND METHOD:A randomized, double-blind, parallel-group study compared the effectiveness and tolerability of three treatments for glaucoma: 2% carteolol/2% pilocarpine fixed-ratio combination (CBS 341A) twice a day, versus a 0.5% timolol/2% pilocarpine fixed combination twice a day versus 2% carteolol twice a d...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：:Variants in LOXL1 are significantly associated with exfoliation syndrome (XFS), however the impact of the associated variants on disease development is not yet understood. Initially the associated missense changes, R141L and G153D, were considered to be pathogenic alleles. Flipping of the risk allele in certain popula...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0000000000000124
更新日期：2014-10-01 00:00:00
