Abstract：
PURPOSE:To study the frequencies and factors associated with 4 disc patterns in primary open-angle glaucoma (POAG) identified in population-based studies: focal glaucomatous (FG type), generalized enlargement of cup (GE type), myopic glaucomatous (MG type), and senile sclerotic glaucomatous (SS type) patterns. SUBJECTS:In total, 270 disc photographs of acceptable quality were extracted from the records of 270 definitive POAG cases diagnosed according to the International Society of Geographical and Epidemiological Ophthalmology Criteria in 2 Japanese population-based glaucoma surveys. One randomly chosen eye from the bilateral POAG cases was included. RESULTS:Using a method of κ coefficient of reproducibility of classification of 0.80 according to a preliminary study, 143 discs were classified as FG, GE, MG, or SS types with respective frequencies of 57% (95% confidence interval [CI], 48-66), 33% (95% CI, 25-42), 7% (95% CI, 3-13), and 3% (95% CI, 0-7), and 127 discs as the miscellaneous type. Multinomial logistic regression analysis showed that the MG type was associated (P=0.052, 0.025, 0.019, and 0.018) with younger age, lower body mass index (BMI), and greater disc area and ovality, and the GE type was associated (P<0.001, 0.036, and 0.056) with greater disc area, corneal radius, and hyperopic refraction than the FG type. CONCLUSIONS:The FG type occurs most frequently in Japanese POAG followed by the GE type. The MG and SS types occurred much less often than previously reported in Japanese. Associations with age, BMI, disc area and ovality, refraction, and corneal radius differed among the FG, GE, and MG types.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Iwase A,Araie M,Kuwayama Y,Murata H,Yamamoto Tdoi
10.1097/IJG.0000000000001240subject
Has Abstractpub_date
2019-06-01 00:00:00pages
487-492issue
6eissn
1057-0829issn
1536-481Xjournal_volume
28pub_type
杂志文章abstract：:Variants in LOXL1 are significantly associated with exfoliation syndrome (XFS), however the impact of the associated variants on disease development is not yet understood. Initially the associated missense changes, R141L and G153D, were considered to be pathogenic alleles. Flipping of the risk allele in certain popula...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0000000000000124
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To evaluate anxiety felt by glaucoma patients. PATIENTS AND METHODS:In total, 472 glaucoma patients responded to a questionnaire on anxiety, subjective symptoms, and vision-related quality of life (VR-QOL) associated with glaucoma. Anxiety was evaluated using the State-Trait Anxiety Inventory (STAI), state anx...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000761
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVES:This study was conducted to evaluate the effect of long-term intraocular pressure reduction with timolol on the incidence of glaucomatous visual field defects and optic nerve cupping in individuals with ocular hypertension and to compare this incidence with that of a similar group on no treatment. ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:To investigate the practice patterns among glaucoma subspecialists in the American Glaucoma Society regarding the management of blebitis. METHODS:An anonymous survey incorporating 14 questions regarding the management of blebitis was mailed to all current active American Glaucoma Society members, including pro...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200108000-00015
更新日期：2001-08-01 00:00:00
abstract：PURPOSE:Subconjunctival mitomycin C has been used in glaucoma filtration surgery with success. A prospective, randomized, masked, placebo-controlled study was performed to evaluate whether single transconjunctival mitomycin C applied either preoperatively or postoperatively would enhance the success of filtration surge...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：PURPOSE:To determine the risk factors for hyphema after trabeculectomy with mitomycin C (MMC). PATIENTS AND METHODS:In total, 420 patients (420 eyes) with glaucoma who underwent trabeculectomy with MMC between June 1, 2005 and December 31, 2010 at Kumamoto University Hospital, Japan, were retrospectively evaluated. Hy...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3182741c85
更新日期：2014-06-01 00:00:00
abstract：:To prevent corneal endothelial cell loss, ciliary sulcus tube insertion is preferred for the pseudophakic eye. However, we sometimes encounter technical difficulties when inserting the tube through the sulcus. Even in cases in which we are able to insert a 23-G needle through the sulcus into the space between the iris...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001602
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To report the histopathologic and immunohistochemical findings from the iridectomy specimen of a patient with acquired unilateral iris heterochromia due to latanoprost. PATIENT AND METHODS:A 45-year-old woman with open-angle glaucoma and unilateral iris heterochromia was evaluated for uncontrolled intraocular ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/00061198-200110000-00009
更新日期：2001-10-01 00:00:00
abstract：PURPOSE OF THE STUDY:The purpose of the study was to evaluate the clinical efficacy of swept-source optical coherence tomography (SS-OCT), we compared the intradevice repeatability of thickness measurements obtained using SS-OCT to that of measurements obtained using spectral domain OCT (SD-OCT), and assessed the inter...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000536
更新日期：2017-02-01 00:00:00
abstract：PURPOSE:To determine the correlation of central corneal thickness (CCT) to Goldmann applanation tonometry (GAT) and dynamic contour tonometry (DCT, PASCAL), and to glaucoma stage as assessed by cup-to-disc ratio (CDR). DESIGN:Prospective, cross-sectional tricenter observation study. PATIENTS AND METHODS:From three gl...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/00061198-200604000-00003
更新日期：2006-04-01 00:00:00
abstract：PURPOSE:The authors report a rare complication of "pseudophakic reverse pupillary block" after a secondary, scleral-fixated intraocular lens implantation using the Yamane technique. METHODS/RESULTS:A 52-year-old male patient was referred for uncontrolled intraocular pressure (IOP) despite 3 topical antiglaucoma medica...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001538
更新日期：2020-07-01 00:00:00
abstract：PURPOSE:To evaluate the effects of flunarizine, a nonselective calcium channel blocker, on intraocular pressure (IOP) in monkeys with laser-induced unilateral glaucoma and on aqueous humor dynamics in normal monkeys. METHODS:The IOP was measured before and hourly for 6 hours after single-dose administration of 0.5%, 1...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e318133a845
更新日期：2008-01-01 00:00:00
abstract：PURPOSE:To investigate the effects of topical instillation of 0.5% tranilast eye drops on intraocular pressure (IOP) and bleb formation after glaucoma filtering surgery. PATIENTS AND METHODS:This was a prospective, randomized, double-masked, and controlled clinical trial. A total of 52 eyes of 52 patients were randoml...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200204000-00008
更新日期：2002-04-01 00:00:00
abstract：PURPOSE:The purpose of this study was to compare intraocular pressure measurements obtained with XPERT, an upgraded model of the noncontact tonometer, with those from Goldmann applanation tonometry. METHODS:An average of three intraocular pressure measurements, generated by the XPERT, was compared with a single readin...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1997-02-01 00:00:00
abstract：PURPOSE:To compare the effect of unoprostone isopropyl 0.12% to that of timolol maleate 0.5% solution given twice daily on the diurnal curve of intraocular pressure (IOP) in patients with primary open-angle glaucoma or ocular hypertension. METHODS:In this investigator-masked, single-center, parallel-group comparison, ...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1998-12-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of CO2 laser-assisted sclerectomy surgery (CLASS) in primary and pseudoexfoliative open-angle glaucoma. MATERIALS AND METHODS:Patients for primary filtration surgery underwent CLASS with a CO2 laser system (OT-134-IOPtiMate, IOPtima Ltd., Ramat Gan, Israel). This self-controlled system...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1097/IJG.0b013e3181f7b14f
更新日期：2012-03-01 00:00:00
abstract：:The lamina cribrosa (LC) is a multilayered, collagenous, sieve-like structure at the deep optic nerve head, and is presumed to be the primary site of axonal injury. According to biomechanical theory, intraocular pressure-induced posterior deformation of the LC causes blockage of axonal transport and alters the ocular ...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0000000000000728
更新日期：2017-09-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of CO2 Laser-assisted Sclerectomy Surgery (CLASS) in primary and pseudoexfoliative open-angle glaucoma. MATERIALS AND METHODS:Single-arm, open-label study included data from 9 medical centers located in 7 countries. Subjects underwent nonpenetrating CLASS procedure with a CO...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/IJG.0000000000000437
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To develop a descriptive system for a glaucoma-specific preference-based health-related quality of life (HRQoL) instrument: the Health Utility for Glaucoma (HUG-5). METHODS:The descriptive system was developed in 2 stages: item identification and item selection. A systematic literature review of HRQoL assessme...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000984
更新日期：2018-07-01 00:00:00
abstract：PRECIS:Repeated use of the Micropulse P3 (MP3) probe during micropulse transscleral cyclophotocoagulation is associated with an increase in laser output over time. PURPOSE:The purpose of this study was to examine the laser efficacy of the MP3 probe following repeated use. METHODS:This was an observational study carri...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001277
更新日期：2019-08-01 00:00:00
abstract：PURPOSE:Estimate patient adherence to glaucoma medications and identify potential determinants of nonadherence. DESIGN:Descriptive study. METHODS:Two hundred patients with open angle glaucoma, ocular hypertension, or glaucoma suspects were interviewed regarding their glaucoma and its treatment and their charts were r...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181815421
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:The aims of this study were to observe the changes in the demand for prescriptions of ocular hypertensive drug (OHD) after cataract surgery, to investigate patterns of change in the required OHD amount in open-angle glaucoma (OAG) and angle-closure glaucoma (ACG) cases, and to determine the associated factors r...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000969
更新日期：2018-07-01 00:00:00
abstract：:A 51-year-old white man presented with multiple episodes of transient painless unilateral vision loss precipitated by sexual intercourse. Examination was significant for closed angles bilaterally. His visual symptoms completely resolved following treatment with laser peripheral iridotomies. ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000165
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:To compare near and distance stereoacuity between patients with primary open-angle glaucoma (POAG) and a control group, and to analyze the associations between stereoacuity and POAG severity. METHODS:This cross-sectional study compared near and distance stereoacuity between the POAG and control groups. The dat...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000963
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To compare the intraocular pressure-lowering effect of unoprostone isopropyl (unoprostone) 0.12% and latanoprost 0.005%. A correlation between the intraocular pressure-lowering effect of unoprostone and latanoprost was also evaluated. METHODS:A single-masked randomized study included 18 patients between 49 and...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200112000-00009
更新日期：2001-12-01 00:00:00
abstract：PURPOSE:To evaluate tonometric outcomes of patients with primary angle closure glaucoma (PACG) who have undergone trabeculectomy with mitomycin C (MMC) with and without concurrent phacoemulsification and to identify risk factors for postoperative failure. PATIENTS AND METHODS:Retrospective cohort study of 44 eyes of 3...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000493
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:To measure the serum bile acids (SBA) in patients with primary open-angle glaucoma (POAG) and to compare with nonglaucomatous controls. PATIENTS AND METHODS:A hospital-based case control study of 90 patients above the age of 40 years was conducted. Patients with POAG formed the study group and individuals with...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000993
更新日期：2018-08-01 00:00:00
abstract：PURPOSE:To report a simple technique for removal of malpositioned Ex-PRESS miniature glaucoma filtration device. PATIENT AND METHODS:A patient who underwent removal of a malpositioned Ex-PRESS shunt from the right eye with wound revision. RESULTS:Description of step-by-step technique for removal of the Ex-PRESS shunt...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31827b1540
更新日期：2014-09-01 00:00:00
abstract：PURPOSE:To characterize and compare the ocular comfort and symptoms of dorzolamide and tear-replacement drops (placebo) in healthy volunteers. PATIENTS AND METHODS:Subjects were randomized in a double-masked fashion to receive each medicine for 6 days twice daily. Patients used a visual analog scale to assess the qual...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200304000-00010
更新日期：2003-04-01 00:00:00
abstract：PURPOSE:To assess the relationship between pupillary light reflex and estimated retinal ganglion cell (RGC) counts in patients with glaucoma. METHODS:We recorded and analyzed pupil responses using an automated binocular pupillometer in 148 patients with glaucoma (mean age 67±11, 49% female) and 71 controls (age 60±9.6...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001183
更新日期：2019-03-01 00:00:00
