Abstract:
PURPOSE:To evaluate the outcome of modified deep sclerectomy [D-lectomy mitomycin C (MMC)] for medically refractory glaucoma patients. METHODS:In a retrospective comparative study, the surgical outcome in 1 eye each of 31 patients who underwent D-lectomy MMC was compared with that of 91 eyes of 91 patients who underwent trabeculectomy with adjunctive MMC. These eyes had a diagnosis of primary open-angle glaucoma or pseudoexfoliation glaucoma, a record of high intraocular pressure (IOP) exceeding 25 mm Hg, and planned for surgical intervention. In the D-lectomy MMC cases, a slit incision at the trabecular meshwork and peripheral iridectomy were created. The "lake" and trabeculo-Descemet membrane ("window") were examined by ultrasound biomicroscope, gonioscopy, and time-domain optical coherence tomography. RESULTS:Postsurgical IOP at 1, 3, 6, and 12 months after the D-lectomy MMC and trabeculectomy MMC were comparable (P=0.63-0.97). The filtering bleb was noted in 14 (45%) of the 31 D-lectomy MMC eyes at 3 months, and their survival was significantly less than trabeculectomy MMC subjects in which 81 of 91 eyes had the bleb at 3 months (P<0.0001). The lake was noted in 29 of 31 D-lectomy MMC eyes. The sealing of the once penetrated trabecular meshwork was complete at 3 months in 23 of 29 eyes by ultrasound biomicroscopic and/or gonioscopic examinations, whereas that was incomplete in 6 eyes. CONCLUSIONS:Addition of a slit incision to the trabecular meshwork and peripheral iridectomy (D-lectomy MMC) improved postsurgical IOP of the deep sclerectomy to the level comparable with trabeculectomy MMC, with a less frequency of the bleb formation.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Chihara E,Okazaki K,Takahashi H,Shoji T,Adachi H,Hayashi Kdoi
10.1097/IJG.0b013e3181752cc8subject
Has Abstractpub_date
2009-02-01 00:00:00pages
132-9issue
2eissn
1057-0829issn
1536-481Xpii
00061198-200902000-00008journal_volume
18pub_type
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更新日期:2018-10-01 00:00:00
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更新日期:2003-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:1992-01-01 00:00:00
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更新日期:2004-12-01 00:00:00
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更新日期:2017-10-01 00:00:00
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更新日期:2013-10-01 00:00:00
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journal_title:Journal of glaucoma
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doi:10.1097/IJG.0b013e3181ca7c7a
更新日期:2010-12-01 00:00:00
abstract:STUDY OBJECTIVES:The association between obstructive sleep apnea syndrome (OSAS) and retinal nerve fiber layer (RNFL) thickness has been examined in many studies. However, the findings are inconsistent. Our goal is to evaluate the association between OSAS and RNFL thickness by performing a meta-analysis. METHODS:We co...
journal_title:Journal of glaucoma
pub_type: 杂志文章,meta分析
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更新日期:2016-04-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00061198-200206000-00011
更新日期:2002-06-01 00:00:00
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更新日期:2018-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/IJG.0000000000001407
更新日期:2020-01-01 00:00:00
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journal_title:Journal of glaucoma
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doi:10.1097/IJG.0000000000000216
更新日期:2016-04-01 00:00:00
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journal_title:Journal of glaucoma
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更新日期:2019-08-01 00:00:00
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更新日期:2008-04-01 00:00:00
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更新日期:2013-12-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2009-08-01 00:00:00
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更新日期:2014-01-01 00:00:00
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更新日期:2013-12-01 00:00:00
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更新日期:2016-07-01 00:00:00
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更新日期:2020-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2013-09-01 00:00:00
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journal_title:Journal of glaucoma
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更新日期:2020-12-29 00:00:00
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更新日期:2016-06-01 00:00:00