当前位置： SCI文献检索 > NEUROBIOLOGY OF LEARNING AND MEMORY期刊下所有文献 > Dorsal hippocampal damage disrupts the auditory context-dependent attenuation of taste neophobia in mice.

Dorsal hippocampal damage disrupts the auditory context-dependent attenuation of taste neophobia in mice.

Abstract：

:Rodents exhibit neophobia for novel tastes, demonstrated by an initial reluctance to drink novel-tasting, potentially-aversive solutions. Taste neophobia attenuates across days if the solution is not aversive, demonstrated by increased consumption as the solution becomes familiar. This attenuation of taste neophobia is context dependent, which has been demonstrated by maintained reluctance to drink the novel tasting solution if the subject has to drink it after being brought to a novel environment. This spatial context-dependent attenuation of taste neophobia has been described and likely depends on the integrity of the dorsal hippocampus because this brain area is crucial for representing space and spatial context associations, but is unnecessary for processing taste memories per se. Whether changing the non-spatial auditory context causes a similar effect on attenuation of taste neophobia and the potential role of the dorsal hippocampus in processing this decidedly non-spatial information has not been determined. Here we demonstrate that changing the non-spatial auditory context affects the attenuation of taste neophobia in mice, and investigate the consequence of hippocampal lesion. The results demonstrate that the non-spatial auditory context-dependent attenuation of taste neophobia in mice is lost following NMDA excitotoxic lesions of the CA1 region of the dorsal hippocampus. These findings demonstrate that the dorsal hippocampus is crucial for the modulation non-associative taste learning by auditory context, neither of which provide information about space.

journal_name

Neurobiol Learn Mem

journal_title

Neurobiology of learning and memory

authors

Grau-Perales AB,Levy ERJ,Fenton AA,Gallo M

doi

10.1016/j.nlm.2018.12.009

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

121-127

eissn

1074-7427

issn

1095-9564

pii

S1074-7427(18)30285-5

journal_volume

157

pub_type

杂志文章

相关文献

NEUROBIOLOGY OF LEARNING AND MEMORY文献大全
  • Impaired fear extinction retention and increased anxiety-like behaviours induced by limited daily access to a high-fat/high-sugar diet in male rats: Implications for diet-induced prefrontal cortex dysregulation.

    abstract：:Anxiety disorders and obesity are both common in youth and young adults. Despite increasing evidence that over-consumption of palatable high-fat/high-sugar "junk" foods leads to adverse neurocognitive outcomes, little is known about the effects of palatable diets on emotional memories and fear regulation. In the prese...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2016.10.002

    authors： Baker KD,Reichelt AC

    更新日期：2016-12-01 00:00:00

  • Post-encoding frontal theta activity predicts incidental memory in the reward context.

    abstract：:Memories for daily events require that individuals integrate initial fragile traces of events over time. Recent evidence suggests that reward anticipation enhances memory performance and amplifies frontal theta activity for remembered items vs. forgotten items. However, little is known about how incidental rewards aft...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2019.01.008

    authors： Pu M,Yu R

    更新日期：2019-02-01 00:00:00

  • The effect of sleep deprivation on the encoding of contextual and non-contextual aspects of emotional memory.

    abstract：:Sleep loss affects emotional memory, but the specific effects on its contextual and non-contextual aspects are unknown. In this study we investigated the possible differential influence of one night of sleep deprivation on the encoding and subsequent recall of these two aspects of emotional information. Forty-eight he...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2016.03.007

    authors： Tempesta D,Socci V,Coppo M,Dello Ioio G,Nepa V,De Gennaro L,Ferrara M

    更新日期：2016-05-01 00:00:00

  • Maintenance of long-term memory storage is dependent on late posttraining Egr-1 expression.

    abstract：:Expression of immediate-early genes, like Egr-1, has been shown to be induced by activity-dependent synaptic plasticity or behavioral training and is widely thought to play an important role in long-term memory (LTM) formation. However, little is known about the role of Egr-1 in the maintenance of memory storage. Here...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2012.08.001

    authors： Katche C,Goldin A,Gonzalez C,Bekinschtein P,Medina JH

    更新日期：2012-10-01 00:00:00

  • Fetal alcohol-exposed rats exhibit differential response to cholinergic drugs on a delay-dependent memory task.

    abstract：:Fetal alcohol exposure in human and rodents produces a number of cognitive deficits including impairments in learning and memory. Recent evidence in our laboratory has shown that fetal alcohol-exposed (FAE) rats respond differently to systemic administration of cholinergic drugs when tested for vigilance and locomotor...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1006/nlme.1999.3909

    authors： Nagahara AH,Handa RJ

    更新日期：1999-11-01 00:00:00

  • Age-related differences in appetitive trace conditioning and novel object recognition procedures.

    abstract：:Appetitive trace conditioning (TC) was examined over 6 months in younger-adult (2-8 months) and middle-aged (12-18 months) male Wistar RccHan rats, to test for early age-related impairment in working memory. Novel object recognition (NOR) was included as a comparison task, to provide a positive control in the event th...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2019.107041

    authors： Marshall HJ,Pezze MA,Fone KCF,Cassaday HJ

    更新日期：2019-10-01 00:00:00

  • Is the unilateral lesion of the left substantia nigra pars compacta sufficient to induce working memory impairment in rats?

    abstract：:Adult male Wistar rats with a substantia nigra pars compacta (SNc) lesion induced by intranigral administration of 1 micromol 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were used as a model of early phase Parkinson's disease (PD). This lesion caused a partial depletion of striatal dopamine (DA). The animals w...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2004.06.006

    authors： Bellissimo MI,Kouzmine I,Ferro MM,de Oliveira BH,Canteras NS,Da Cunha C

    更新日期：2004-09-01 00:00:00

  • The effects of selective cholinergic basal forebrain lesions and aging upon expectancy in the rat.

    abstract：:The effects of selective cholinergic cell loss within the basal forebrain (BF) were determined using a task that requires shifting of attention between two visual stimuli. Discriminability between two stimuli and response bias were determined in young and old F-344 rats given BF injections of IgG-192 saporin (100 ng)....

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1006/nlme.1997.3768

    authors： Stoehr JD,Mobley SL,Roice D,Brooks R,Baker LM,Wiley RG,Wenk GL

    更新日期：1997-05-01 00:00:00

  • Progesterone to ovariectomized mice enhances cognitive performance in the spontaneous alternation, object recognition, but not placement, water maze, and contextual and cued conditioned fear tasks.

    abstract：:Research on how steroid hormones mediate mnemonic processes have focused on effects of 17beta-estradiol (E(2)); yet, progesterone (P(4)) co-varies with E(2) across endogenous hormonal milieu, and itself may influence cognitive processes. We investigated the hypothesis that acute P(4) treatment enhances cognitive perfo...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2008.03.005

    authors： Frye CA,Walf AA

    更新日期：2008-07-01 00:00:00

  • Consolidation of spatial memory in the rat: Findings using zeta-inhibitory peptide.

    abstract：:Whether or not spatial memories reorganize in the rodent brain is an unanswered question that carries the importance of whether the rodent provides a suitable animal model of human retrograde amnesia. The finding of equally impaired recent and remote spatial memory could reflect the continued importance of the hippoca...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2016.11.003

    authors： Hales JB,Ocampo AC,Broadbent NJ,Clark RE

    更新日期：2016-12-01 00:00:00

  • Lesions of ventrolateral striatum eliminate lose-shift but not win-stay behaviour in rats.

    abstract：:Animals tend to repeat actions that are associated with reward delivery, whereas they tend to shift responses to alternate choices following reward omission. These so-called win-stay and lose-shift responses are employed by a wide range of animals in a variety of decision-making scenarios, and depend on dissociated re...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2018.08.022

    authors： Thapa R,Gruber AJ

    更新日期：2018-11-01 00:00:00

  • Weak involvement of octopamine in aversive taste learning in a snail.

    abstract：:The pond snail Lymnaea stagnalis is capable of learning taste aversion by pairing presentations of a sucrose solution and an electric shock and consolidating it into long-term memory (LTM), which is referred to as conditioned taste aversion (CTA). We asked here if the neurotransmitter octopamine is involved in CTA. We...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2017.04.010

    authors： Aonuma H,Kaneda M,Hatakeyama D,Watanabe T,Lukowiak K,Ito E

    更新日期：2017-05-01 00:00:00

  • Subordinate male mice show long-lasting differences in spatial learning that persist when housed alone.

    abstract：:In the wild, house mice live in social groups, whereas in the laboratory male mice are often singly housed. Environmental enrichment such as that provided by social housing has been argued to improve the cognitive performance of laboratory animals in experimental tests. The aim of the present study was to test the cos...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2005.08.004

    authors： Fitchett AE,Collins SA,Barnard CJ,Cassaday HJ

    更新日期：2005-11-01 00:00:00

  • Inhibition of guanylate cyclase and protein kinase G impairs retention for the passive avoidance task in the day-old chick.

    abstract：:Nitric oxide (NO) is a highly labile chemical messenger which has previously been implicated in memory processes in a variety of learning paradigms and species. However, there is only limited evidence to suggest which enzymes are acted upon by NO during the formation of memory. The present study investigates the role ...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1006/nlme.2001.4021

    authors： Edwards TM,Rickard NS,Ng KT

    更新日期：2002-05-01 00:00:00

  • Glycine(B) receptor antagonists and partial agonists prevent memory deficits in inhibitory avoidance learning.

    abstract：:Activation of N-methyl-d-aspartate (NMDA) receptors has been hypothesized to mediate certain forms of learning and memory. This hypothesis is based on the ability of competitive and uncompetitive NMDA receptor antagonists to disrupt learning. We investigated the effects of glycine site antagonists and partial agonists...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1006/nlme.1999.3947

    authors： Viu E,Zapata A,Capdevila J,Skolnick P,Trullas R

    更新日期：2000-09-01 00:00:00

  • The consolidation of inhibitory avoidance memory in mice depends on the intensity of the aversive stimulus: The involvement of the amygdala, dorsal hippocampus and medial prefrontal cortex.

    abstract：:Several studies using inhibitory avoidance models have demonstrated the importance of limbic structures, such as the amygdala, dorsal hippocampus and medial prefrontal cortex, in the consolidation of emotional memory. However, we aimed to investigate the role of the amygdala (AMG), dorsal hippocampus (DH) and medial p...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2016.01.012

    authors： Canto-de-Souza L,Mattioli R

    更新日期：2016-04-01 00:00:00

  • ORAI1-dependent synaptic plasticity in rat hippocampal neurons.

    abstract：:It is well established that neurons are plastic and can change the strength of their connections with other neurons depending on their recent history. While many molecular entities involved in plastic processes were already described, the role of a store-operated calcium channel ORAI1 in neuronal plasticity is not kno...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2016.12.024

    authors： Tshuva RY,Korkotian E,Segal M

    更新日期：2017-04-01 00:00:00

  • Molecular mechanisms controlling protein synthesis in memory reconsolidation.

    abstract：:It is currently well established that the synthesis of new proteins (mRNA translation) is required for long-lasting synaptic plasticity and memory formation. Translation in the brain is regulated primarily at the initiation stage by general as well as by gene-specific mechanisms. Stored memories can become sensitive t...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章,评审

    doi：10.1016/j.nlm.2017.04.015

    authors： Roesler R

    更新日期：2017-07-01 00:00:00

  • ADHD symptoms are associated with decreased activity of fast sleep spindles and poorer procedural overnight learning during adolescence.

    abstract：:ADHD and its subclinical symptoms have been associated with both disturbed sleep and weakened overnight memory consolidation. As sleep spindle activity during NREM sleep plays a key role in both sleep maintenance and memory consolidation, we examined the association between subclinical ADHD symptoms and sleep spindle ...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2018.12.004

    authors： Merikanto I,Kuula L,Makkonen T,Halonen R,Lahti J,Heinonen K,Räikkönen K,Pesonen AK

    更新日期：2019-01-01 00:00:00

  • Enhanced cognitive activity--over and above social or physical activity--is required to protect Alzheimer's mice against cognitive impairment, reduce Abeta deposition, and increase synaptic immunoreactivity.

    abstract：:Although social, physical, and cognitive activities have each been suggested to reduce the risk of Alzheimer's disease (AD), epidemiologic studies cannot determine which activity or combination of activities is most important. To address this question, mutant APP transgenic AD mice were reared long-term in one of four...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2007.07.007

    authors： Cracchiolo JR,Mori T,Nazian SJ,Tan J,Potter H,Arendash GW

    更新日期：2007-10-01 00:00:00

  • Why bother using non-human primate models of cognitive disorders in translational research?

    abstract：:Although everyone would agree that successful translation of therapeutic candidates for central nervous disorders should involve non-human primate (nhp) models of cognitive disorders, we are left with the paucity of publications reporting either the target validation or the actual preclinical testing in heuristic nhp ...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章,评审

    doi：10.1016/j.nlm.2015.06.012

    authors： Camus S,Ko WK,Pioli E,Bezard E

    更新日期：2015-10-01 00:00:00

  • The neural basis of individual differences in memory performance in young and older adults: Using the encoding/retrieval flip account as framework.

    abstract：:Aging is associated with cognitive decline, specifically in episodic memory. However, there are large individual differences in the extent of this decline and previous research suggests that these are associated with differences in executive functioning (EF). These EF differences, and associated differences in the enc...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2020.107251

    authors： Fu L,Maes JHR,Kessels RPC,Huijbers W

    更新日期：2020-09-01 00:00:00

  • Effects of intrastriatal injections of platelet-activating factor and the PAF antagonist BN 52021 on memory.

    abstract：:The present experiments examined the effects of posttraining intra-dorsal striatal (i.e., caudate-putamen) injections of the phospholipid methylcarbamyl platelet-activating factor (mc-PAF) and the platelet-activating factor (PAF) antagonist BN 52021 on memory using a striatal-dependent cued water maze task. Male Long-...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1006/nlme.1996.0058

    authors： Packard MG,Teather LA,Bazan NG

    更新日期：1996-09-01 00:00:00

  • Coupling of prefrontal gamma amplitude and theta phase is strengthened in trace eyeblink conditioning.

    abstract：:Trace eyeblink conditioning requires animals to associate a neutral stimulus (CS) and an aversive periorbital shock (US) that occurred moment later. Acquisition in this conditioning depends on several forebrain regions including the hippocampus, medial prefrontal, and entorhinal cortices in addition to the cerebellum....

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2012.12.014

    authors： Shearkhani O,Takehara-Nishiuchi K

    更新日期：2013-02-01 00:00:00

  • Adult hippocampal MeCP2 preserves the genomic responsiveness to learning required for long-term memory formation.

    abstract：:MeCP2 is required both during postnatal neurodevelopment and throughout the adult life for brain function. Although it is well accepted that MeCP2 in the maturing nervous system is critical for establishing normal development, the functions of MeCP2 during adulthood are poorly understood. Particularly, the requirement...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2018.02.010

    authors： Gulmez Karaca K,Brito DVC,Zeuch B,Oliveira AMM

    更新日期：2018-03-01 00:00:00

  • A therapeutic dose of memantine improves the performance of rats in an active place avoidance task under the continuous dissociation of distal room and proximal arena cues.

    abstract：:Memory is related to the function of N-methyl-D-aspartate (NMDA) receptors. Depending on the dose, NMDA receptor antagonists (such as memantine or MK-801) can impair memory and/or cognitive as well as procedural functions, while they also can prevent the long-term toxic effects of over-excitation of these receptors in...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2019.03.011

    authors： Wesierska M,Svoboda J,Stuchlik A

    更新日期：2019-07-01 00:00:00

  • d-cycloserine reverses the detrimental effects of stress on learning in females and enhances retention in males.

    abstract：:Exposure to acute, inescapable stress produces a facilitation of subsequent classical eyeblink conditioning in male rats. The same stress exposure produces a profound deficit in classical eyeblink conditioning in females. Activation of N-methyl-d-aspartate receptors (NMDAr) is necessary for the effect of stress on lea...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2009.08.002

    authors： Waddell J,Mallimo E,Shors T

    更新日期：2010-01-01 00:00:00

  • Frontal cortex stroke-induced impairment in spatial working memory on the trial-unique nonmatching-to-location task in mice.

    abstract：:Stroke-induced cognitive impairments are of significant concern, however mechanisms that underpin these impairments remain poorly understood and researched. To further characterise cognitive impairments in our frontal cortex stroke model, and to align our assessments with what is used clinically, we tested young C57BL...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2020.107355

    authors： Houlton J,Barwick D,Clarkson AN

    更新日期：2021-01-01 00:00:00

  • Time-course of 5-HT(6) receptor mRNA expression during memory consolidation and amnesia.

    abstract：:Growing evidence indicates that antagonists of the 5-hydroxytryptamine (serotonin) receptor(6) (5-HT(6)) improve memory and reverse amnesia although the mechanisms involved are poorly understood. Hence, in this paper RT-PCR was used to evaluate changes in mRNA expression of 5-HT(6) receptor in trained and untrained ra...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2009.08.009

    authors： Huerta-Rivas A,Pérez-García G,González-Espinosa C,Meneses A

    更新日期：2010-01-01 00:00:00

  • Stress during puberty boosts metabolic activation associated with fear-extinction learning in hippocampus, basal amygdala and cingulate cortex.

    abstract：:Adolescence is characterized by major developmental changes that may render the individual vulnerable to stress and the development of psychopathologies in a sex-specific manner. Earlier we reported lower anxiety-like behavior and higher risk-taking and novelty seeking in rats previously exposed to peri-pubertal stres...

    journal_title：Neurobiology of learning and memory

    pub_type： 杂志文章

    doi：10.1016/j.nlm.2012.05.006

    authors： Toledo-Rodriguez M,Pitiot A,Paus T,Sandi C

    更新日期：2012-07-01 00:00:00