Age-related differences in appetitive trace conditioning and novel object recognition procedures.

abstract：:Four experiments were conducted to examine social and emotional memory in the R6/2 transgenic mouse model of Huntington's disease. First, R6/2 mice were tested in a social transmission of food preference task where they had to acquire a preference for a flavoured food (acquisition) and subsequently to learn a preferen...

journal_title：Neurobiology of learning and memory

authors： Ciamei A,Morton AJ

更新日期：2008-05-01 00:00:00

abstract：:Sign-tracking behavior, in which animals interact with a cue that predicts reward, provides an example of how incentive salience can be attributed to cues and elicit motivation. The nucleus accumbens (NAc) and ventral pallidum (VP) are two regions involved in cue-driven motivation. The VP, and NAc subregions including...

journal_title：Neurobiology of learning and memory

authors： Smedley EB,DiLeo A,Smith KS

更新日期：2019-07-01 00:00:00

abstract：:The entorhinal cortex (EC) has been shown to be an integral piece of the hippocampal memory system. It sits in a unique position within the brain with strong, intricate, reciprocal connectivity with the hippocampus as well as a vast array of neocortical regions. Topographical patterns of afferent and efferent projecti...

journal_title：Neurobiology of learning and memory

authors： Morrissey MD,Takehara-Nishiuchi K

更新日期：2014-11-01 00:00:00

abstract：:Relapse to drug use is often precipitated by exposure to drug associated cues that evoke craving. Cue-induced drug craving has been observed in both animals and humans to increase over the first few weeks of abstinence and remain high over extended periods, a phenomenon known as 'incubation of craving'. As adolescence...

journal_title：Neurobiology of learning and memory

authors： Madsen HB,Zbukvic IC,Luikinga SJ,Lawrence AJ,Kim JH

更新日期：2017-09-01 00:00:00

abstract：:Pre-verbal infants and non-human animals associate small numbers with the left space and large numbers with the right space. Birds and primates, trained to identify a given position in a sagittal series of identical positions, whenever required to respond on a left/right oriented series, referred the given position st...

journal_title：Neurobiology of learning and memory

authors： Rugani R,Vallortigara G,Regolin L

更新日期：2016-09-01 00:00:00

abstract：:Studies in rodents have demonstrated that glucocorticoids enhance memory consolidation but impair delayed memory retrieval. Similar findings have been reported in humans. Emotional items are better remembered than neutral items. However, it is unknown if emotional valence influences the effects of cortisol on retrieva...

journal_title：Neurobiology of learning and memory

authors： Kuhlmann S,Kirschbaum C,Wolf OT

更新日期：2005-03-01 00:00:00

abstract：:Transcriptional changes in the hippocampus are required for memory formation, and these changes are regulated by numerous post-translational modifications of chromatin-associated proteins. One of the epigenetic marks that has been implicated in memory formation is histone 3 lysine 4 trimethylation (H3K4me3), and this ...

journal_title：Neurobiology of learning and memory

authors： Collins BE,Sweatt JD,Greer CB

更新日期：2019-05-01 00:00:00

abstract：:It has recently become widely appreciated that value-based decision making is supported by multiple computational strategies. In particular, animal and human behavior in learning tasks appears to include habitual responses described by prominent model-free reinforcement learning (RL) theories, but also more deliberati...

journal_title：Neurobiology of learning and memory

authors： Doll BB,Shohamy D,Daw ND

更新日期：2015-01-01 00:00:00

abstract：:There is ongoing debate concerning whether new protein synthesis is necessary for, or even contributes to, memory formation and storage. This review summarizes a contemporary model proposing a role for altered protein synthesis in memory formation and its subsequent stabilization. One defining aspect of the model is t...

journal_title：Neurobiology of learning and memory

authors： Klann E,Sweatt JD

更新日期：2008-03-01 00:00:00

abstract：:The efficacy of synaptic transmission between two neurons changes as a function of the history of previous activations of the synaptic connection. This history dependence can be characterized by examining the dependence of transmission on the frequency of stimulation. In this framework synaptic plasticity can also be ...

journal_title：Neurobiology of learning and memory

authors： Markram H,Gupta A,Uziel A,Wang Y,Tsodyks M

更新日期：1998-07-01 00:00:00

abstract：:Traditional learning theory has developed models that can accurately predict and describe the course of learned behavior. These "psychological process" models rely on hypothetical constructs that are usually thought to be not directly measurable or manipulable. Recently, and mostly in parallel, the neural mechanisms u...

journal_title：Neurobiology of learning and memory

authors： Fanselow MS,Zelikowsky M,Perusini J,Barrera VR,Hersman S

更新日期：2014-02-01 00:00:00

abstract：:Evidence indicating a role for the nucleus accumbens in the development of latent inhibition of learning has accumulated. Two experiments were conducted using Wistar rats to investigate this role directly. Experiment 1 used a conditioned emotional response paradigm to assess the effects of discrete electrolytic lesion...

journal_title：Neurobiology of learning and memory

authors： Tai CT,Cassaday HJ,Feldon J,Rawlins JN

更新日期：1995-07-01 00:00:00

abstract：:Previous studies have reported that drugs affecting neuromodulatory systems within the basolateral amygdala (BLA), including drugs affecting muscarinic cholinergic receptors, modulate the consolidation of many kinds of training, including contextual fear conditioning (CFC). The present experiments investigated the inv...

journal_title：Neurobiology of learning and memory

authors： Boccia MM,Blake MG,Baratti CM,McGaugh JL

更新日期：2009-01-01 00:00:00

abstract：:Anxiety disorders and obesity are both common in youth and young adults. Despite increasing evidence that over-consumption of palatable high-fat/high-sugar "junk" foods leads to adverse neurocognitive outcomes, little is known about the effects of palatable diets on emotional memories and fear regulation. In the prese...

journal_title：Neurobiology of learning and memory

authors： Baker KD,Reichelt AC

更新日期：2016-12-01 00:00:00

abstract：:Inappropriate defense-alerting reaction to fear is a common feature of neuropsychiatric diseases. Therefore, impairments in brain circuits, as well as in molecular pathways underlying the neurovegetative adjustments to fear may play an essential role on developing neuropsychiatric disorders. Here we tested the hypothe...

journal_title：Neurobiology of learning and memory

authors： Lazaroni TL,Bastos CP,Moraes MF,Santos RS,Pereira GS

更新日期：2016-01-01 00:00:00

abstract：:Aiming at exploring the brain's structural organisation underlying successful second language learning, we investigate the anatomy of the perisylvian language network in a group of healthy adults, consisting of participants with high and average language analytical abilities. Utilising deterministic tractography, six ...

journal_title：Neurobiology of learning and memory

authors： Kepinska O,Lakke EAJF,Dutton EM,Caspers J,Schiller NO

更新日期：2017-10-01 00:00:00

abstract：:Long-term memory formation requires gene expression after acquisition of new information. The first step in the regulation of gene expression is the participation of transcription factors (TFs) such as nuclear factor kappa B (NF-кB), which are present before the neuronal activity induced by training. It was proposed t...

journal_title：Neurobiology of learning and memory

authors： Zalcman G,Federman N,de la Fuente V,Romano A

更新日期：2015-03-01 00:00:00

abstract：:Accumulating evidence indicates that homeostatic plasticity mechanisms dynamically adjust synaptic strength to promote stability that is crucial for memory storage. Our previous studies have shown that prior training in conditioned taste aversion (CTA) prevents the subsequent induction of long-term potentiation (LTP) ...

journal_title：Neurobiology of learning and memory

authors： Rivera-Olvera A,Nelson-Mora J,Gonsebatt ME,Escobar ML

更新日期：2018-10-01 00:00:00

abstract：:The present experiments examined the effects of posttraining intra-dorsal striatal (i.e., caudate-putamen) injections of the phospholipid methylcarbamyl platelet-activating factor (mc-PAF) and the platelet-activating factor (PAF) antagonist BN 52021 on memory using a striatal-dependent cued water maze task. Male Long-...

journal_title：Neurobiology of learning and memory

authors： Packard MG,Teather LA,Bazan NG

更新日期：1996-09-01 00:00:00

abstract：:Nitric oxide (NO) is a highly labile chemical messenger which has previously been implicated in memory processes in a variety of learning paradigms and species. However, there is only limited evidence to suggest which enzymes are acted upon by NO during the formation of memory. The present study investigates the role ...

journal_title：Neurobiology of learning and memory

authors： Edwards TM,Rickard NS,Ng KT

更新日期：2002-05-01 00:00:00

abstract：:The immunotoxin 192-saporin, infused intracerebroventricularly into rats, destroys cholinergic neurons in the basal forebrain nuclei. Doses required for complete cholinergic loss also kill some Purkinje cells. The immunotoxin OX7-saporin, when infused intraventricularly into rats, destroys Purkinje cells in a pattern ...

journal_title：Neurobiology of learning and memory

authors： Waite JJ,Wardlow ML,Power AE

更新日期：1999-05-01 00:00:00

abstract：:It has been well established that moderate physiological or emotional arousal modulates memory. However, there is some controversy about whether the source of arousal must be semantically related to the information to be remembered. To test this idea, 35 healthy young adult participants learned a list of common nouns ...

journal_title：Neurobiology of learning and memory

authors： Nielson KA,Yee D,Erickson KI

更新日期：2005-07-01 00:00:00

abstract：:Learning is ubiquitous in the animal kingdom but has been studied extensively in only a handful of species. Moreover, learning studied under laboratory conditions is typically unrelated to the animal's natural environment or life history. Here, we designed a task relevant to the natural behavior of male African cichli...

journal_title：Neurobiology of learning and memory

authors： Wood LS,Desjardins JK,Fernald RD

更新日期：2011-03-01 00:00:00

abstract：:Place navigation engrams acquired with intact brain can be retrieved with either eye and are stored in both hemispheres. The retrieval circuitry was examined by testing an overtrained rat under lidocaine inactivation of the hippocampus, visual cortex, and superior colliculus. Thirty-three hooded rats with implanted ca...

journal_title：Neurobiology of learning and memory

authors： Turner LF,Liu Z,Bures J

更新日期：1997-07-01 00:00:00

abstract：:Research has shown that a single presentation of the conditioned stimulus prior to extinction training can diminish conditioned responses. However, replication has proven difficult and appears to be limited by boundary conditions. Here we tested the boundary condition of memory strength by comparing the effect of rein...

journal_title：Neurobiology of learning and memory

authors： Kitamura H,Johnston P,Johnson L,Strodl E

更新日期：2020-10-01 00:00:00

abstract：:Autism Spectrum Disorders are a heterogeneous group of neurodevelopmental disorders, with rising incidence but little effective therapeutic intervention available. Currently two main clinical features are described to diagnose ASDs: impaired social interaction and communication, and repetitive behaviors. Much work has...

journal_title：Neurobiology of learning and memory

authors： Pasciuto E,Borrie SC,Kanellopoulos AK,Santos AR,Cappuyns E,D'Andrea L,Pacini L,Bagni C

更新日期：2015-10-01 00:00:00

abstract：:Fetal alcohol exposure in human and rodents produces a number of cognitive deficits including impairments in learning and memory. Recent evidence in our laboratory has shown that fetal alcohol-exposed (FAE) rats respond differently to systemic administration of cholinergic drugs when tested for vigilance and locomotor...

journal_title：Neurobiology of learning and memory

authors： Nagahara AH,Handa RJ

更新日期：1999-11-01 00:00:00

abstract：:Recent evidence suggests that an interaction of noradrenaline (NE) and cortisol (CORT) during encoding leads to greater consolidation of emotional memories. Convergent models of posttraumatic stress disorder (PTSD) suggest the release of CORT and NE lead to greater intrusive memories in PTSD. This study examined the e...

journal_title：Neurobiology of learning and memory

authors： Nicholson EL,Bryant RA,Felmingham KL

更新日期：2014-07-01 00:00:00

abstract：:Neuronal plasticity and neurogenesis occur in the adult hippocampus and in other brain structures such as the olfactory bulb and often involve the neural cell adhesion molecule NCAM. During an olfactory associative discrimination learning task, NCAM polysialylation triggers neuronal plasticity in the adult hippocampus...

journal_title：Neurobiology of learning and memory

authors： Mione J,Manrique C,Duhoo Y,Roman FS,Guiraudie-Capraz G

更新日期：2016-04-01 00:00:00

abstract：:The purpose of this study was to explore the effects of slow-wave disruption on positive and negative word recognition in a sample of healthy control participants and those with major depressive disorder. Prior to sleep, participants learned a set of emotional and neutral words during an encoding task by responding wh...

journal_title：Neurobiology of learning and memory

authors： Goldschmied JR,Cheng P,Kim HS,Casement M,Armitage R,Deldin PJ

更新日期：2015-11-01 00:00:00