Abstract：
:Research has shown that a single presentation of the conditioned stimulus prior to extinction training can diminish conditioned responses. However, replication has proven difficult and appears to be limited by boundary conditions. Here we tested the boundary condition of memory strength by comparing the effect of reinforcement rate to assess its role in post-retrieval extinction. Eighty university students had undergone a three-day fear conditioning experiment in which two partial reinforcement schedules (40%, 80%) were applied. The findings indicated that both low and high partial reinforcement groups did not demonstrate recovery of conditioned responses after post-retrieval extinction. In contrast, both groups demonstrated significant recovery to standard extinction with significantly greater recovery in the 80% group relative to the 40% group. Additionally, we found that greater physiological arousal during memory retrieval significantly predicted recovery of fear at test phase. We conclude that when compared to a lower partial reinforcement schedule, a higher partial reinforcement resulted in the formation of a stronger memory as indicated by greater physiological arousal during memory reactivation and recovery of conditioned responses after standard extinction, but that it does not function as a boundary condition of post-retrieval extinction. These data are significant because it is the first study to investigate the effect of varying partial reinforcement schedules on fear recovery and add to the body of literature that continue to identify sources of failure in the application of post-retrieval extinction.
journal_name
Neurobiol Learn Memjournal_title
Neurobiology of learning and memoryauthors
Kitamura H,Johnston P,Johnson L,Strodl Edoi
10.1016/j.nlm.2020.107285subject
Has Abstractpub_date
2020-10-01 00:00:00pages
107285eissn
1074-7427issn
1095-9564pii
S1074-7427(20)30129-5journal_volume
174pub_type
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pub_type： 杂志文章,评审
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journal_title：Neurobiology of learning and memory
pub_type： 杂志文章,评审
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