Hippocampal Arc (Arg3.1) expression is induced by memory recall and required for memory reconsolidation in trace fear conditioning.

abstract：:Prediction error is recognized as a necessary boundary condition for memory reactivation and reconsolidation. Furthermore, behavioral manipulations (e.g., visuospatial interference tasks, like Tetris) have been shown to be effective at disrupting reactivated memory. In the present study, participants created a memory ...

journal_title：Neurobiology of learning and memory

authors： Gotthard GH,Gura H

更新日期：2018-12-01 00:00:00

abstract：:Studies in rodents have demonstrated that glucocorticoids enhance memory consolidation but impair delayed memory retrieval. Similar findings have been reported in humans. Emotional items are better remembered than neutral items. However, it is unknown if emotional valence influences the effects of cortisol on retrieva...

journal_title：Neurobiology of learning and memory

authors： Kuhlmann S,Kirschbaum C,Wolf OT

更新日期：2005-03-01 00:00:00

abstract：:Previously, we demonstrated that mice in which the gene for the L-type voltage-gated calcium channel Ca(V)1.3 is deleted (Ca(V)1.3 knockout mice) exhibit an impaired ability to consolidate contextually-conditioned fear. Given that this form of Pavlovian fear conditioning is critically dependent on the basolateral comp...

journal_title：Neurobiology of learning and memory

authors： McKinney BC,Sze W,Lee B,Murphy GG

更新日期：2009-11-01 00:00:00

abstract：:Memory consolidation is associated with sleep physiology but the contribution of specific sleep stages remains controversial. To clarify the contribution of REM sleep, participants were administered two REM sleep-sensitive tasks to determine if associated changes occurred only in REM sleep. Twenty-two participants (7 ...

journal_title：Neurobiology of learning and memory

authors： Nielsen T,O'Reilly C,Carr M,Dumel G,Godin I,Solomonova E,Lara-Carrasco J,Blanchette-Carrière C,Paquette T

更新日期：2015-07-01 00:00:00

abstract：:The present study examined the effects of posttraining ethanol administration upon retention of an appetitive task using a variety of retention behaviors associated with the task. Male C57BL/6J mice were individually trained to find a cheese pellet placed in the corner of an open field. Five behavioral measures were u...

journal_title：Neurobiology of learning and memory

authors： Ladner CJ,Babbini M,Davies DL,Parker ES,Alkana RL

更新日期：2001-01-01 00:00:00

abstract：:Socially housed mice with cytotoxic lesions of the hippocampus do not exhibit social recognition memory 30 min following exposure to a juvenile mouse, however the social recognition memory of singly housed rats is unimpaired. The present study tests the hypothesis that social housing of rats could render social recogn...

journal_title：Neurobiology of learning and memory

authors： Squires AS,Peddle R,Milway SJ,Harley CW

更新日期：2006-01-01 00:00:00

abstract：:Recent research has begun to demonstrate that specific subunits of GABA(A) receptors may be involved in the normal expression of specific behaviors. The present research used mice with GABA(A) receptors whose alpha1 subunits contained mutations of serine 270 to histidine and leucine 277 to alanine in the TM2 region. T...

journal_title：Neurobiology of learning and memory

authors： Berry RB,Werner DF,Wang X,Jablonski MM,Homanics GE,Mittleman G,Matthews DB

更新日期：2008-10-01 00:00:00

abstract：:The impact of past history on behavior across the life span is largely unknown. This is why the role of previous experience in subsequent memory performances has been studied in a combined longitudinal (animals repeatedly tested) and cross-sectional (animals tested once at various ages) study, in male Sprague-Dawley r...

journal_title：Neurobiology of learning and memory

authors： Dellu F,Mayo W,Vallee M,Le Moal M,Simon H

更新日期：1997-03-01 00:00:00

abstract：:Numerous preclinical studies show that acute cannabinoid administration impairs cognitive performance. Almost all of this research has employed cannabinoid injections, however, whereas smoking is the preferred route of cannabis administration in humans. The goal of these experiments was to systematically determine how...

journal_title：Neurobiology of learning and memory

authors： Blaes SL,Orsini CA,Holik HM,Stubbs TD,Ferguson SN,Heshmati SC,Bruner MM,Wall SC,Febo M,Bruijnzeel AW,Bizon JL,Setlow B

更新日期：2019-01-01 00:00:00

abstract：:Rats were trained to run on a staircase stopping on the 3rd, 6th, 9th, and 12th steps (correct responses). Stopping on any other step was considered an error. Acute administration of 0.5 mg/kg of arecoline 15 min before the trial improved behavior and 3.5 mg/kg of arecoline caused a reduction of correct responses. An ...

journal_title：Neurobiology of learning and memory

authors： Molinengo L,Orsetti M,Pastorello B,Scordo I,Ghi P

更新日期：1995-03-01 00:00:00

abstract：:The aim of the present study was to investigate the effects of paradoxical sleep deprivation (PSD) for 96 h on the learning/memory processes in rats submitted to the plus-maze discriminative avoidance task (PM-DAT), which simultaneously evaluates learning, memory, anxiety and motor function. Four experiments were perf...

journal_title：Neurobiology of learning and memory

authors： Alvarenga TA,Patti CL,Andersen ML,Silva RH,Calzavara MB,Lopez GB,Frussa-Filho R,Tufik S

更新日期：2008-11-01 00:00:00

abstract：:Fetal alcohol exposure in human and rodents produces a number of cognitive deficits including impairments in learning and memory. Recent evidence in our laboratory has shown that fetal alcohol-exposed (FAE) rats respond differently to systemic administration of cholinergic drugs when tested for vigilance and locomotor...

journal_title：Neurobiology of learning and memory

authors： Nagahara AH,Handa RJ

更新日期：1999-11-01 00:00:00

abstract：:An enormous amount of research has been aimed at identifying biological and environmental factors that are contributing to the current global obesity pandemic. The present paper reviews recent findings which suggest that obesity is attributable, at least in part, to a disruption of the Pavlovian control of energy regu...

journal_title：Neurobiology of learning and memory

authors： Davidson TL,Sample CH,Swithers SE

更新日期：2014-02-01 00:00:00

abstract：:Cognitive impairments are amongst the most debilitating deficits of schizophrenia and the best predictor of functional outcome. Schizophrenia is hypothesized to have a neurodevelopmental origin, making animal models of neurodevelopmental insult important for testing predictions that early insults will impair cognitive...

journal_title：Neurobiology of learning and memory

authors： O'Reilly KC,Perica MI,Fenton AA

更新日期：2016-10-01 00:00:00

abstract：:Sleep loss affects emotional memory, but the specific effects on its contextual and non-contextual aspects are unknown. In this study we investigated the possible differential influence of one night of sleep deprivation on the encoding and subsequent recall of these two aspects of emotional information. Forty-eight he...

journal_title：Neurobiology of learning and memory

authors： Tempesta D,Socci V,Coppo M,Dello Ioio G,Nepa V,De Gennaro L,Ferrara M

更新日期：2016-05-01 00:00:00

abstract：:One of the major achievements of the last century of research in experimental psychology is the identification of a coherent set of theories and principles to characterize the nature of simple forms of associative learning. Major advances are also currently being made at a rapid pace in the neurobiology of associative...

journal_title：Neurobiology of learning and memory

authors： Delamater AR,Lattal KM

更新日期：2014-02-01 00:00:00

abstract：:New neurons are continually produced in the adult mammalian brain from progenitor cells located in specific brain regions, including the subgranular zone (SGZ) of the dentate gyrus of the hippocampus. We hypothesized that neurogenesis occurs in the canine brain and is reduced with age. We examined neurogenesis in the ...

journal_title：Neurobiology of learning and memory

authors： Siwak-Tapp CT,Head E,Muggenburg BA,Milgram NW,Cotman CW

更新日期：2007-09-01 00:00:00

abstract：:The single-trial passive avoidance task is a useful procedure for examining learning and memory in the young chick. However, it has recently been suggested that discrepant results reported by different laboratories are due to differences in training procedure. The present study investigated a number of parameters surr...

journal_title：Neurobiology of learning and memory

authors： Crowe SF,Hale MW

更新日期：2002-09-01 00:00:00

abstract：:Two experiments examined the effects of total stimulus preexposure on latent inhibition (LI) in a conditioned taste aversion procedure with rats. Experiment 1 varied the frequency and duration of saccharin preexposures. LI was an increasing function of the product of frequency x duration. Experiment 2 kept saccharin e...

journal_title：Neurobiology of learning and memory

authors： De la Casa G,Lubow RE

更新日期：1995-09-01 00:00:00

abstract：:Chronic stress leads to a dysregulated inhibitory tone that could impact hippocampal-dependent spatial learning and memory. The present study examined whether spatial memory deficits resulting from chronic stress could be overcome by antagonizing the GABAA receptor, a prominent inhibitory receptor of GABA in the hippo...

journal_title：Neurobiology of learning and memory

authors： Nishimura KJ,Ortiz JB,Conrad CD

更新日期：2017-11-01 00:00:00

abstract：:We have previously reported that extinction of escape behavior in the water maze due to the removal of the platform coincided with the development of behavioral "despair" in aged and adult rats, as assessed by immobility. The present study examines further predictions derived from the hypothesis that the withholding o...

journal_title：Neurobiology of learning and memory

authors： Schulz D,Huston JP,Buddenberg T,Topic B

更新日期：2007-03-01 00:00:00

abstract：:The present experiments examined the effects of posttraining intra-dorsal striatal (i.e., caudate-putamen) injections of the phospholipid methylcarbamyl platelet-activating factor (mc-PAF) and the platelet-activating factor (PAF) antagonist BN 52021 on memory using a striatal-dependent cued water maze task. Male Long-...

journal_title：Neurobiology of learning and memory

authors： Packard MG,Teather LA,Bazan NG

更新日期：1996-09-01 00:00:00

abstract：:It has been proposed that normal waking levels of acetylcholine (ACH) are important for initial memory acquisition, and that decreased ACH is critical for memory consolidation. Sleep is thought to benefit memory consolidation in part due to the predominance of low ACH levels observed during non-rapid eye movement slee...

journal_title：Neurobiology of learning and memory

authors： Tucker MA,Taylor K,Merchant R,George S,Stoddard C,Kopera K

更新日期：2018-11-01 00:00:00

abstract：:Previous studies have reported that drugs affecting neuromodulatory systems within the basolateral amygdala (BLA), including drugs affecting muscarinic cholinergic receptors, modulate the consolidation of many kinds of training, including contextual fear conditioning (CFC). The present experiments investigated the inv...

journal_title：Neurobiology of learning and memory

authors： Boccia MM,Blake MG,Baratti CM,McGaugh JL

更新日期：2009-01-01 00:00:00

abstract：:Growing evidence indicates that antagonists of the 5-hydroxytryptamine (serotonin) receptor(6) (5-HT(6)) improve memory and reverse amnesia although the mechanisms involved are poorly understood. Hence, in this paper RT-PCR was used to evaluate changes in mRNA expression of 5-HT(6) receptor in trained and untrained ra...

journal_title：Neurobiology of learning and memory

authors： Huerta-Rivas A,Pérez-García G,González-Espinosa C,Meneses A

更新日期：2010-01-01 00:00:00

abstract：:We developed a single-trial cue-location memory task in which rats experienced an auditory cue while exploring an environment. They then recalled and avoided the sound origination point after the cue was paired with shock in a separate context. Subjects with medial prefrontal cortical (mPFC) lesions made no such avoid...

journal_title：Neurobiology of learning and memory

authors： Rawson T,O'Kane M,Talk A

更新日期：2010-01-01 00:00:00

abstract：:The objective of the present study was to observe the effects of pre-training or post-training administration of dicyclomine, a M1 muscarinic antagonist, on inhibitory avoidance (IA) and contextual fear conditioning (CFC) and to investigate if the effects observed with the pre-training administration of dicyclomine ar...

journal_title：Neurobiology of learning and memory

authors： Soares JC,Fornari RV,Oliveira MG

更新日期：2006-09-01 00:00:00

abstract：:The beneficial effects of caloric restriction (CR) on health and life expectancy are well documented, although its ability to slow down age-dependent cognitive decline and the underlying biochemical changes remains unclear. Therefore, the aim of this study was to investigate the effects of CR on spatial memory in aged...

journal_title：Neurobiology of learning and memory

authors： Rojic-Becker D,Portero-Tresserra M,Martí-Nicolovius M,Vale-Martínez A,Guillazo-Blanch G

更新日期：2019-12-01 00:00:00

abstract：:Four experiments were conducted to examine social and emotional memory in the R6/2 transgenic mouse model of Huntington's disease. First, R6/2 mice were tested in a social transmission of food preference task where they had to acquire a preference for a flavoured food (acquisition) and subsequently to learn a preferen...

journal_title：Neurobiology of learning and memory

authors： Ciamei A,Morton AJ

更新日期：2008-05-01 00:00:00

abstract：:An increasing number of studies using human subjects substantiate the use of transcranial direct current stimulation (tDCS) as a noninvasive approach to treat various neurological symptoms. tDCS has been tested in conditions from motor to cognition dysfunctions. Performance enhancement of healthy subjects using tDCS h...

journal_title：Neurobiology of learning and memory

authors： Rohan JG,Miklasevich MK,McInturf SM,Bechmann NA,Moore RJ,Hatcher-Solis C,Jankord R

更新日期：2020-01-01 00:00:00