Abstract：
:Prediction error is recognized as a necessary boundary condition for memory reactivation and reconsolidation. Furthermore, behavioral manipulations (e.g., visuospatial interference tasks, like Tetris) have been shown to be effective at disrupting reactivated memory. In the present study, participants created a memory with positive valence by viewing an uplifting video of a young boy who built an arcade out of cardboard boxes. Two weeks later, memory for the video was reactivated with a prediction error (i.e., new information was added) or without a prediction error (i.e., no new information was added). Following memory reactivation, participants completed a novel visuospatial interference task (i.e., a complex word search) or a control task (i.e., sitting quietly). One week following reactivation, participants completed two memory tests (i.e., free recall and recognition). Results showed that the visuospatial interference task was effective in reducing free recall, but only in the group that received a prediction error during retrieval. No other significant differences were observed, including on the recognition test. These results expand the literature on reconsolidation by showing that destabilization of memory with a positive emotional valence requires a prediction error and that a novel visuospatial interference task (i.e., complex word search) is an effective behavioral manipulation for decreasing free recall.
journal_name
Neurobiol Learn Memjournal_title
Neurobiology of learning and memoryauthors
Gotthard GH,Gura Hdoi
10.1016/j.nlm.2018.11.003subject
Has Abstractpub_date
2018-12-01 00:00:00pages
80-85eissn
1074-7427issn
1095-9564pii
S1074-7427(18)30258-2journal_volume
156pub_type
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