Relational memory generalization and integration in a transitive inference task with and without instructed awareness.

Abstract:

:Two experiments investigated the potential facilitative effects of prior instructed awareness and predetermined learning criteria on humans' ability to make transitive inference (TI) judgments. Participants were first exposed to a learning phase and required to learn five premise pairs (A+B-, B+C-, C+D-, D+E-, E+F-). Testing followed, where participants made judgments on novel non-endpoint (BD, BE and CE) and endpoint inferential pairs (AC, AD, AE, AF, BF, CF and DF), as well as learned premise pairs. Across both experiments, one group were made aware that the stimuli could be arranged in a hierarchy, while another group were not given this instruction. Results demonstrated that prior instructional task awareness led to a minor performance advantage, but that this difference was not significant. Furthermore, in Experiment 2, inferential test trial accuracy was not correlated with a post-experimental measure of awareness. Thus, the current findings suggest that successful TI task performance may occur in the absence of awareness, and that repeated exposure to learning and test phases may allow weak inferential performances to emerge gradually. Further research and alternative methods of measuring awareness and its role in TI are needed.

journal_name

Neurobiol Learn Mem

authors

Munnelly A,Dymond S

doi

10.1016/j.nlm.2014.01.004

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

169-77

eissn

1074-7427

issn

1095-9564

pii

S1074-7427(14)00005-7

journal_volume

109

pub_type

杂志文章
  • Stress during puberty boosts metabolic activation associated with fear-extinction learning in hippocampus, basal amygdala and cingulate cortex.

    abstract::Adolescence is characterized by major developmental changes that may render the individual vulnerable to stress and the development of psychopathologies in a sex-specific manner. Earlier we reported lower anxiety-like behavior and higher risk-taking and novelty seeking in rats previously exposed to peri-pubertal stres...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2012.05.006

    authors: Toledo-Rodriguez M,Pitiot A,Paus T,Sandi C

    更新日期:2012-07-01 00:00:00

  • Androgens' effects to enhance learning may be mediated in part through actions at estrogen receptor-beta in the hippocampus.

    abstract::Testosterone (T) may enhance cognitive performance. However, its mechanisms are not well understood. First, we hypothesized that if T's effects are mediated in part through actions of its 5alpha-reduced metabolites, dihydrotestosterone (DHT) and/or 3alpha-androstanediol (3alpha-diol) in the hippocampus, then T, DHT, a...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2006.07.001

    authors: Edinger KL,Frye CA

    更新日期:2007-01-01 00:00:00

  • Commonly-occurring polymorphisms in the COMT, DRD1 and DRD2 genes influence different aspects of motor sequence learning in humans.

    abstract::Performing sequences of movements is a ubiquitous skill that involves dopamine transmission. However, it is unclear which components of the dopamine system contribute to which aspects of motor sequence learning. Here we used a genetic approach to investigate the relationship between different components of the dopamin...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2015.09.009

    authors: Baetu I,Burns NR,Urry K,Barbante GG,Pitcher JB

    更新日期:2015-11-01 00:00:00

  • Newly acquired and reactivated contextual fear memories are more intense and prone to generalize after activation of prelimbic cortex NMDA receptors.

    abstract::Activity in the rodent prelimbic (PL) cortex contributes to consolidation, retrieval and reconsolidation of learned fear. The PL cortex is considered homologous to the primate dorsal anterior cingulate cortex (dACC). In patients with post-traumatic stress disorder (PTSD), the dACC is often reported to be hyperactive a...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2016.12.002

    authors: Vanvossen AC,Portes MAM,Scoz-Silva R,Reichmann HB,Stern CAJ,Bertoglio LJ

    更新日期:2017-01-01 00:00:00

  • Effects of intrastriatal injections of platelet-activating factor and the PAF antagonist BN 52021 on memory.

    abstract::The present experiments examined the effects of posttraining intra-dorsal striatal (i.e., caudate-putamen) injections of the phospholipid methylcarbamyl platelet-activating factor (mc-PAF) and the platelet-activating factor (PAF) antagonist BN 52021 on memory using a striatal-dependent cued water maze task. Male Long-...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.1996.0058

    authors: Packard MG,Teather LA,Bazan NG

    更新日期:1996-09-01 00:00:00

  • Involvement of the basolateral amygdala in muscarinic cholinergic modulation of extinction memory consolidation.

    abstract::Previous studies have reported that drugs affecting neuromodulatory systems within the basolateral amygdala (BLA), including drugs affecting muscarinic cholinergic receptors, modulate the consolidation of many kinds of training, including contextual fear conditioning (CFC). The present experiments investigated the inv...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2008.07.012

    authors: Boccia MM,Blake MG,Baratti CM,McGaugh JL

    更新日期:2009-01-01 00:00:00

  • Regulation of glutamate synapses by nicotinic acetylcholine receptors in auditory cortex.

    abstract::Acetylcholine plays an important role in regulating the processing of sensory stimuli, and understanding its specific cellular actions is critical to understanding how sensory cortex develops and functions in different behavioral states. Here we review recent work on the cellular effects of nicotinic receptor activati...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章,评审

    doi:10.1016/s1074-7427(03)00062-5

    authors: Metherate R,Hsieh CY

    更新日期:2003-11-01 00:00:00

  • Inhibition of guanylate cyclase and protein kinase G impairs retention for the passive avoidance task in the day-old chick.

    abstract::Nitric oxide (NO) is a highly labile chemical messenger which has previously been implicated in memory processes in a variety of learning paradigms and species. However, there is only limited evidence to suggest which enzymes are acted upon by NO during the formation of memory. The present study investigates the role ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.2001.4021

    authors: Edwards TM,Rickard NS,Ng KT

    更新日期:2002-05-01 00:00:00

  • The effect of amygdala lesions on conditional and unconditional vocalizations in rats.

    abstract::Electrolytic lesions centered on the amygdaloid central nucleus (ACe) resulted in the inability of rats to acquire a Pavlovian conditional vocalization response. Conditioning consisted of pairing a light conditional stimulus with a tailshock unconditional stimulus (US). The thresholds of three unconditional responses ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/s1074-7427(03)00002-9

    authors: Borszcz GS,Leaton RN

    更新日期:2003-05-01 00:00:00

  • Heart rate changes during conditioning-specific reflex modification of the rabbit's (Oryctolagus cuniculus) nictitating membrane response.

    abstract::Conditioning-specific reflex modification (CRM) of the rabbit's nictitating membrane response (NMR) involves changes in responding to an unconditioned stimulus (US) when the US is tested in the absence of the conditioned stimulus. Previous experiments have shown that CRM is a function of the type and intensity of the ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2005.06.003

    authors: Schreurs BG,Smith-Bell CA

    更新日期:2005-09-01 00:00:00

  • Immunization with either prion protein fragment 95-123 or the fragment-specific antibodies rescue memory loss and neurodegenerative phenotype of neurons in olfactory bulbectomized mice.

    abstract::Epidemiological studies demonstrated association between head injury (HI) and the subsequent development of Alzheimer's disease (AD). Certain hallmarks of AD, e.g. amyloid-β (Aβ) containing deposits, may be found in patients following traumatic BI (TBI). Recent studies uncover the cellular prion protein, PrP(C), as a ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2013.10.019

    authors: Bobkova NV,Medvinskaya NI,Kamynina AV,Aleksandrova IY,Nesterova IV,Samokhin AN,Koroev DO,Filatova MP,Nekrasov PV,Abramov AY,Leonov SV,Volpina OM

    更新日期:2014-01-01 00:00:00

  • D-cycloserine in the basolateral amygdala prevents extinction and enhances reconsolidation of odor-reward associative learning in rats.

    abstract::It is well established that D-cycloserine (DCS), a partial agonist of the NMDA receptor glycine site, enhances learning and memory processes. Although the effects of DCS have been especially elucidated in the extinction and reconsolidation of aversive behavioral paradigms or drug-related behaviors, they have not been ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2012.11.003

    authors: Portero-Tresserra M,Martí-Nicolovius M,Guillazo-Blanch G,Boadas-Vaello P,Vale-Martínez A

    更新日期:2013-02-01 00:00:00

  • The effects of selective cholinergic basal forebrain lesions and aging upon expectancy in the rat.

    abstract::The effects of selective cholinergic cell loss within the basal forebrain (BF) were determined using a task that requires shifting of attention between two visual stimuli. Discriminability between two stimuli and response bias were determined in young and old F-344 rats given BF injections of IgG-192 saporin (100 ng)....

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.1997.3768

    authors: Stoehr JD,Mobley SL,Roice D,Brooks R,Baker LM,Wiley RG,Wenk GL

    更新日期:1997-05-01 00:00:00

  • Hippocampal Arc (Arg3.1) expression is induced by memory recall and required for memory reconsolidation in trace fear conditioning.

    abstract::Mounting evidence suggests that long-lasting, protein synthesis-dependent changes in synaptic strength accompany both the initial acquisition and subsequent recall of specific memories. Within brain areas thought to be important for learning and memory, including the hippocampus, learning-related plasticity is likely ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2013.06.021

    authors: Chia C,Otto T

    更新日期:2013-11-01 00:00:00

  • Mapping number to space in the two hemispheres of the avian brain.

    abstract::Pre-verbal infants and non-human animals associate small numbers with the left space and large numbers with the right space. Birds and primates, trained to identify a given position in a sagittal series of identical positions, whenever required to respond on a left/right oriented series, referred the given position st...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2016.05.010

    authors: Rugani R,Vallortigara G,Regolin L

    更新日期:2016-09-01 00:00:00

  • Effect of neonatal dentate gyrus lesion on allothetic and idiothetic navigation in rats.

    abstract::Goal-directed navigation is believed to be the combined product of idiothetic and allothetic orientation. Although both navigation systems require the hippocampal formation, it is probable that different circuits implement them. Examination of Long-Evans rats with dentate gyrus lesions induced by neonatal X-ray irradi...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.2000.3975

    authors: Czéh B,Stuchlik A,Wesierska M,Cimadevilla JM,Pokorný J,Seress L,Bures J

    更新日期:2001-03-01 00:00:00

  • Hippocampal coupling with cortical and subcortical structures in the context of memory consolidation.

    abstract::Memory consolidation is a gradual process through which episodic memories become incorporated into long-term 'semantic' representations. It likely involves reactivation of neural activity encoding the recent experience during non-REM sleep. A critical prerequisite for memory consolidation is precise coordination of re...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章,评审

    doi:10.1016/j.nlm.2018.04.004

    authors: Skelin I,Kilianski S,McNaughton BL

    更新日期:2019-04-01 00:00:00

  • d-cycloserine reverses the detrimental effects of stress on learning in females and enhances retention in males.

    abstract::Exposure to acute, inescapable stress produces a facilitation of subsequent classical eyeblink conditioning in male rats. The same stress exposure produces a profound deficit in classical eyeblink conditioning in females. Activation of N-methyl-d-aspartate receptors (NMDAr) is necessary for the effect of stress on lea...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2009.08.002

    authors: Waddell J,Mallimo E,Shors T

    更新日期:2010-01-01 00:00:00

  • Mice with targeted genetic reduction of GABA(A) receptor alpha1 subunits display performance differences in Morris water maze tasks.

    abstract::Recent research has begun to demonstrate that specific subunits of GABA(A) receptors may be involved in the normal expression of specific behaviors. The present research used mice with GABA(A) receptors whose alpha1 subunits contained mutations of serine 270 to histidine and leucine 277 to alanine in the TM2 region. T...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2008.06.004

    authors: Berry RB,Werner DF,Wang X,Jablonski MM,Homanics GE,Mittleman G,Matthews DB

    更新日期:2008-10-01 00:00:00

  • Participation of NK1 receptors of the amygdala on the processing of different types of fear.

    abstract::The amygdala, medial hypothalamus, dorsal periaqueductal gray (dPAG), superior and inferior colliculus together constitutes the encephalic aversion system which has been considered the main neural substrate for the integration of unconditioned aversive behavioral states. Within the amygdala the basolateral nucleus (BL...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2013.03.004

    authors: Carvalho MC,Santos JM,Bassi GS,Brandão ML

    更新日期:2013-05-01 00:00:00

  • Prefrontal NMDA receptors expressed in excitatory neurons control fear discrimination and fear extinction.

    abstract::N-methyl-D-aspartate receptors (NMDARs) are critically involved in various learning mechanisms including modulation of fear memory, brain development and brain disorders. While NMDARs mediate opposite effects on medial prefrontal cortex (mPFC) interneurons and excitatory neurons, NMDAR antagonists trigger profound cor...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2014.12.012

    authors: Vieira PA,Corches A,Lovelace JW,Westbrook KB,Mendoza M,Korzus E

    更新日期:2015-03-01 00:00:00

  • Micro- and macrostructure of learning in active avoidance: a quantitative approach.

    abstract::The dynamics of learning in the Active Avoidance test was analyzed at the trials level as well as at the level of daily sessions, each comprising numerous trials. The two scales (large scale for the sessions and small scale for the trials) were demonstrated to be mutually independent. The intermediate derived scales (...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.1996.0009

    authors: Giuliani A,Mancini AM,Ghirardi O,Ramacci MT,Voronina T,Sirabella P,Colosimo A

    更新日期:1996-01-01 00:00:00

  • Expression of polysialyltransferases (STX and PST) in adult rat olfactory bulb after an olfactory associative discrimination task.

    abstract::Neuronal plasticity and neurogenesis occur in the adult hippocampus and in other brain structures such as the olfactory bulb and often involve the neural cell adhesion molecule NCAM. During an olfactory associative discrimination learning task, NCAM polysialylation triggers neuronal plasticity in the adult hippocampus...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2016.01.011

    authors: Mione J,Manrique C,Duhoo Y,Roman FS,Guiraudie-Capraz G

    更新日期:2016-04-01 00:00:00

  • Limbic-striatal memory systems and drug addiction.

    abstract::Drug addiction can be understood as a pathological subversion of normal brain learning and memory processes strengthened by the motivational impact of drug-associated stimuli, leading to the establishment of compulsive drug-seeking habits. Such habits evolve through a cascade of complex associative processes with Pavl...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1006/nlme.2002.4103

    authors: Robbins TW,Everitt BJ

    更新日期:2002-11-01 00:00:00

  • Effects of stress and motivation on performing a spatial task.

    abstract::Learning is ubiquitous in the animal kingdom but has been studied extensively in only a handful of species. Moreover, learning studied under laboratory conditions is typically unrelated to the animal's natural environment or life history. Here, we designed a task relevant to the natural behavior of male African cichli...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2010.12.002

    authors: Wood LS,Desjardins JK,Fernald RD

    更新日期:2011-03-01 00:00:00

  • Slow-wave disruption enhances the accessibility of positive memory traces.

    abstract::The purpose of this study was to explore the effects of slow-wave disruption on positive and negative word recognition in a sample of healthy control participants and those with major depressive disorder. Prior to sleep, participants learned a set of emotional and neutral words during an encoding task by responding wh...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2015.09.006

    authors: Goldschmied JR,Cheng P,Kim HS,Casement M,Armitage R,Deldin PJ

    更新日期:2015-11-01 00:00:00

  • Maintenance of enriched environment-induced changes of auditory spatial sensitivity and expression of GABAA, NMDA, and AMPA receptor subunits in rat auditory cortex.

    abstract::Enriched environment (EE) has an important role in the development and plasticity of the brain. In this study, we investigated the maintenance of early EE exposure-induced changes of spatial sensitivity, and the possible underlying mechanisms of this maintenance. We found that, compared with the age-matched control, t...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2010.08.008

    authors: Cai R,Zhou X,Guo F,Xu J,Zhang J,Sun X

    更新日期:2010-11-01 00:00:00

  • The perisylvian language network and language analytical abilities.

    abstract::Aiming at exploring the brain's structural organisation underlying successful second language learning, we investigate the anatomy of the perisylvian language network in a group of healthy adults, consisting of participants with high and average language analytical abilities. Utilising deterministic tractography, six ...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2017.07.003

    authors: Kepinska O,Lakke EAJF,Dutton EM,Caspers J,Schiller NO

    更新日期:2017-10-01 00:00:00

  • Is the unilateral lesion of the left substantia nigra pars compacta sufficient to induce working memory impairment in rats?

    abstract::Adult male Wistar rats with a substantia nigra pars compacta (SNc) lesion induced by intranigral administration of 1 micromol 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were used as a model of early phase Parkinson's disease (PD). This lesion caused a partial depletion of striatal dopamine (DA). The animals w...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2004.06.006

    authors: Bellissimo MI,Kouzmine I,Ferro MM,de Oliveira BH,Canteras NS,Da Cunha C

    更新日期:2004-09-01 00:00:00

  • Transcriptional changes before and after forgetting of a long-term sensitization memory in Aplysia californica.

    abstract::Most long-term memories are forgotten, becoming progressively less likely to be recalled. Still, some memory fragments may persist, as savings memory (easier relearning) can be detected long after recall has become impossible. What happens to a memory trace during forgetting that makes it inaccessible for recall and y...

    journal_title:Neurobiology of learning and memory

    pub_type: 杂志文章

    doi:10.1016/j.nlm.2018.09.007

    authors: Patel U,Perez L,Farrell S,Steck D,Jacob A,Rosiles T,Krause E,Nguyen M,Calin-Jageman RJ,Calin-Jageman IE

    更新日期:2018-11-01 00:00:00