Abstract:
:Coupling between dynamical heterogeneity of ionic liquids and their structural periodicity on different length-scales can be directly probed by quasielastic neutron scattering with polarization analysis. The technique provides the tools to investigate single-particle and cooperative ion motions separately and, thus, dynamics of ion associations affecting the net charge transport can be experimentally explored. The focus of this study is the structure-dynamic relationship in the protic ionic liquid, triethylammonium triflate, characterized by strong hydrogen bonds between cations and anions. The site-selective deuterium/hydrogen-isotope substitution was applied to modulate the relative contributions of different atom groups to the total coherent and incoherent scattering signal. This approach in combination with molecular dynamics simulations allowed us to obtain a sophisticated description of cation self-diffusion and confined ion pair dynamics from the incoherent spectral component by using the acidic proton as a tagged particle. The coherent contribution of the neutron spectra demonstrated substantial ion association leading to collective ion migration that preserves charge alteration on picosecond time scale, as well as correlation of the localized dynamics occurring between adjacent ions.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Burankova T,Mora Cardozo JF,Rauber D,Wildes A,Embs JPdoi
10.1038/s41598-018-34481-wsubject
Has Abstractpub_date
2018-11-06 00:00:00pages
16400issue
1issn
2045-2322pii
10.1038/s41598-018-34481-wjournal_volume
8pub_type
杂志文章abstract::Lipidomic analyses address the problem of characterizing the lipid components of given cells, tissues and organisms by means of chromatographic separations coupled to high-resolution, tandem mass spectrometry analyses. A number of software tools have been developed to help in the daunting task of mass spectrometry sig...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-70259-9
更新日期:2020-08-07 00:00:00
abstract::The Ebola filovirus causes severe hemorrhagic fever with a high fatality rate in humans. The primary structural matrix protein VP40 displays transformer-protein characteristics and exists in different conformational and oligomeric states. VP40 plays crucial roles in viral assembly and budding at the plasma membrane of...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-28077-7
更新日期:2018-06-27 00:00:00
abstract::The use of biopurification systems (BPS) constitutes an efficient strategy to eliminate pesticides from polluted wastewaters from farm activities. BPS environments contain a high microbial density and diversity facilitating the exchange of information among bacteria, mediated by mobile genetic elements (MGEs), which p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep28284
更新日期:2016-06-20 00:00:00
abstract::Pregnancy and puerperium are typified by marked biobehavioral changes. These changes, which are traceable in both mothers and fathers, play an important role in parenthood and may modulate social cognition abilities. However, the latter effects remain notably unexplored in parents of newborns (PNs). To bridge this gap...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-62622-7
更新日期:2020-04-01 00:00:00
abstract::Wolfram syndrome (WS) is a rare neurodegenerative disorder that is mainly characterized by diabetes mellitus, optic nerve atrophy, deafness, and progressive brainstem degeneration. Treatment with GLP-1 receptor agonists has shown a promising anti-diabetic effect in WS treatment in both animal models and in human patie...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52295-2
更新日期:2019-10-31 00:00:00
abstract::When acoustic signals from different sound sources are mixed upon arrival at the ears, the auditory system organizes these acoustic elements by their features. This study shows that individuals with autism spectrum disorder (ASD) performed better in terms of hearing a target sequence among distractors that had similar...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10524
更新日期:2015-05-22 00:00:00
abstract::Mobility of people and goods during the Upper Paleolithic has proven difficult to reconstruct given the relative rareness of remains. Nevertheless, archaeological contexts like the Late Pleistocene horizon of Borsuka Cave (Southern Poland) represent a unique opportunity to explore patterns of objects' transportation a...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67017-2
更新日期:2020-06-25 00:00:00
abstract::Both CC and CXC-class chemokines drive inflammatory disease. Tick salivary chemokine-binding proteins (CKBPs), or evasins, specifically bind subsets of CC- or CXC-chemokines, and could precisely target disease-relevant chemokines. Here we have used yeast surface display to identify two tick evasins: a CC-CKBP, P1243 f...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24568-9
更新日期:2018-04-20 00:00:00
abstract::We analysed the imaging findings of macular telangiectasia (MacTel) type 2 in Korea using spectral domain optical coherence tomography (SD-OCT) and investigated their relationship with visual acuity and clinical stages. A retrospective multicentre cross-sectional study was conducted in six tertiary hospitals in Korea ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-73803-9
更新日期:2020-10-06 00:00:00
abstract::Caspase-2 is known to be involved in oxidative-stress mediated neuronal cell death. In this study, we demonstrated that rotenone-induced neuronal cell death is mediated by caspase-2 activation via PIDDosome formation. Our newly designed TAT-fused peptides, which contains wild-type helix number3 (H3) from RAIDD and PID...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31198
更新日期:2016-08-09 00:00:00
abstract::In this paper, we present an evolutionary trust game, taking punishment and protection into consideration, to investigate the formation of trust in the so-called sharing economy from a population perspective. This sharing economy trust model comprises four types of players: a trustworthy provider, an untrustworthy pro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55384-4
更新日期:2019-12-24 00:00:00
abstract::The extensive reliance on insecticides to control Aedes aegypti mosquitoes and disrupt transmission of dengue, chikungunya and Zika has fueled the emergence of widespread resistance to insecticides. Mismatch between the frequency of pyrethroid resistance in mosquitoes and the occurrence of pyrethroid-based insecticide...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-30968-8
更新日期:2018-08-22 00:00:00
abstract::A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-018-26061-9
更新日期:2018-05-15 00:00:00
abstract::This corrects the article DOI: 10.1038/srep46290. ...
journal_title:Scientific reports
pub_type: 杂志文章,已发布勘误
doi:10.1038/srep46823
更新日期:2017-05-22 00:00:00
abstract::Recently, 5-hydroxymethylcytosine patterning across the tumor genome was considered as a hallmark of cancer development and progression. However, locus-specific difference of hydroxymethylation between colorectal cancer and normal tissue is unknown. In this study, we performed a newly developed method, HMST-seq, to pr...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep31826
更新日期:2016-08-22 00:00:00
abstract::This work presents a new method for assisting in the identification process of missing persons in several contexts, such as enforced disappearances. We apply a Bayesian technique to incorporate non-genetic variables in the construction of prior information. In that way, we can learn from the already-solved cases of a ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-59841-3
更新日期:2020-03-19 00:00:00
abstract::In this study we present an image analysis methodology capable of quantifying morphological changes in tissue collagen fibril organization caused by pathological conditions. Texture analysis based on first-order statistics (FOS) and second-order statistics such as gray level co-occurrence matrix (GLCM) was explored to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep02190
更新日期:2013-01-01 00:00:00
abstract::Cephalotaxus oliveri is an endangered tertiary relict conifer endemic to China. The species survives in a wide range from west to east with heterogeneous climatic conditions. Precipitation and temperature are main restrictive factors for distribution of C. oliveri. In order to comprehend the mechanism of adaptive evol...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25031
更新日期:2016-04-26 00:00:00
abstract::Long non-coding RNAs (lncRNAs) form the largest transcript class in the human transcriptome. These lncRNA are expressed not only in the cells, but they are also present in the cell-derived extracellular vesicles such as exosomes. The function of these lncRNAs in cancer biology is not entirely clear, but they appear to...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24922
更新日期:2016-04-22 00:00:00
abstract::Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel cancer-suppressing mechanism, via the secretion of bioactive factors by mammary cells, that is present in domesticated mammals with a low mammary cancer incidence. Sp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77639-1
更新日期:2020-11-25 00:00:00
abstract::The aim of this systematic review was to assess the performance of anthropometric tools to determine obesity in the general population (CRD42018086888). Our review included 32 studies. To detect obesity with body mass index (BMI), the meta-analyses rendered a sensitivity of 51.4% (95% CI 38.5-64.2%) and a specificity ...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/s41598-020-69498-7
更新日期:2020-07-29 00:00:00
abstract::The graft-versus-leukemia effect reminds us to observe the allogeneic cell elicited anti-tumor immune responses. Here we immunized recipient B6 mice with different types of allogenic leukocytes and found that vaccination with allogenic dendritic cells (alloDC) elicited the most efficient protection against broad-spect...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-52151-3
更新日期:2019-10-29 00:00:00
abstract::The kynurenine pathway (KP) is dysregulated in neuroinflammatory diseases including Alzheimer's disease (AD), however has not been investigated in preclinical AD characterized by high neocortical amyloid-β load (NAL), prior to cognitive impairment. Serum KP metabolites were measured in the cognitively normal KARVIAH c...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-25968-7
更新日期:2018-05-22 00:00:00
abstract::The role of changes in dopamine neuronal activity during the development of symptoms in affective disorders remains controversial. Here, we show that inactivation of NMDA receptors on dopaminergic neurons in adult mice led to the development of affective disorder-like symptoms. The loss of NMDA receptors altered activ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep37171
更新日期:2016-11-17 00:00:00
abstract::Enhanced and immediate expression of cyclooxygenase-2 (COX-2) mRNA is observed in IL-1β-stimulated OA chondrocytes but the synthesis of protein found significantly delayed. Here we investigated the role of stress granules (SGs), ribonucleoprotein complexes that regulate mRNA translation, in the delayed translation of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep27611
更新日期:2016-06-08 00:00:00
abstract::Ocean acidification is predicted to have detrimental effects on many marine organisms and ecological processes. Despite growing evidence for direct impacts on specific species, few studies have simultaneously considered the effects of ocean acidification on individuals (e.g. consequences for energy budgets and resourc...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep20194
更新日期:2016-01-29 00:00:00
abstract::The presence of missing values (MVs) in label-free quantitative proteomics greatly reduces the completeness of data. Imputation has been widely utilized to handle MVs, and selection of the proper method is critical for the accuracy and reliability of imputation. Here we present a comparative study that evaluates the p...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81279-4
更新日期:2021-01-19 00:00:00
abstract::The valosin-containing protein (VCP) participates in signaling pathways essential for cell homeostasis in multiple tissues, however, its function in the heart in vivo remains unknown. Here we offer the first description of the expression, function and mechanism of action of VCP in the mammalian heart in vivo in both n...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep46324
更新日期:2017-04-20 00:00:00
abstract::PP2A is a master controller of multiple inflammatory signaling pathways. It is a target in asthma; however the molecular mechanisms by which PP2A controls inflammation warrant further investigation. In A549 lung epithelial cells in vitro we show that inhibition of basal PP2A activity by okadaic acid (OA) releases rest...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep10063
更新日期:2015-05-18 00:00:00
abstract::Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages. Here, we use a low-carbon based strategy to cultivate low-abundance bacteria from Spongia officinalis. This approach favoured the growth of Alphaproteoba...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-38737-x
更新日期:2019-02-13 00:00:00