Abstract:
:Pancreatic adenocarcinoma (PDAC) is mostly refractory to immunotherapies. In this issue of Immunity, Li et al. (2018) generate a library of clonal PDAC tumors to examine the tumor-intrinsic features shaping the anti-tumor immune response and find that tumor cell-derived CXCL1 directly blunts T cell infiltration and reduces responsiveness to immunotherapy.
journal_name
Immunityjournal_title
Immunityauthors
Horton B,Spranger Sdoi
10.1016/j.immuni.2018.07.001subject
Has Abstractpub_date
2018-07-17 00:00:00pages
11-13issue
1eissn
1074-7613issn
1097-4180pii
S1074-7613(18)30302-9journal_volume
49pub_type
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