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Cellulose hydrogel with tunable shape and mechanical properties: From rigid cylinder to soft scaffold.

Abstract：

:Cellulose hydrogel from aqueous solution of lithium bromide demonstrated excellent tunability of mechanical property and shape. A series of compression tests showed that cellulose hydrogel covered a wide range of mechanical property, where the compressive Young's modulus was controllable from 30 kPa to 1.3 MPa by changing the initial concentration of cellulose solution. Meanwhile, the diameter of the building block of gel, namely nano-fibrous cellulose, was constant at 15-20 nm irrelevant of the initial concentration of cellulose solution. Moreover, thanks to the biocompatibility of cellulose, the cultivation of cartilage tissue was successful in the micro-porous sponge-like cellulose hydrogel prepared by salt-leaching process. These findings show that this environmentally-benign versatile gel offers a new substrate for the biomaterial-based nanomaterial in biomedical applications.

journal_name

Int J Biol Macromol

journal_title

International journal of biological macromolecules

authors

Isobe N,Komamiya T,Kimura S,Kim UJ,Wada M

doi

10.1016/j.ijbiomac.2018.05.071

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

625-631

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(18)31200-5

journal_volume

117

pub_type

杂志文章

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