Abstract：
PURPOSE:The purpose this study is to evaluate the efficacy of multiparametric ultrasound-targeted biopsies in patients undergoing initial biopsy of the prostate for the suspicion of prostate cancer. MATERIALS AND METHODS:A total of 167 patients who are biopsy naïve underwent multiparametric ultrasound-targeted biopsy of the prostate. All patients had a transrectal ultrasound which included gray-scale evaluation and color Doppler evaluation. 12-core biopsies were performed on all patients, based on sextant anatomy; however, all cores were directed toward visually abnormal areas of the prostate as identified by multiparametric ultrasound, when such areas were present. RESULTS:Of 167 patients undergoing biopsy, a total of 111 (66.5%) were positive for cancer. Of these, 78 (70.3%) had a Gleason grade ≥ 7 and 33 (29.7%) had a Gleason grade ≤ 6. Of those undergoing radical prostatectomy 29 of 38 (76.3%) had biopsy Gleason grade ≥ 7, while nine of 38 (23.7%) had a Gleason grade ≤ 6. Only four of 38 (10.5%) patients who had final pathologic staging underwent surgical therapy for disease of low-malignant potential (Gleason ≤ 6). CONCLUSION:On initial biopsy for prostate cancer, multiparametric ultrasound-targeted biopsy compares favorably to the published performance of multiparametric MRI-TRUS fusion-targeted biopsy in terms of positive biopsy rate and the detection of disease of low-malignant potential.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Fulgham PFdoi
10.1007/s00345-018-2187-9subject
Has Abstractpub_date
2018-05-01 00:00:00pages
713-718issue
5eissn
0724-4983issn
1433-8726pii
10.1007/s00345-018-2187-9journal_volume
36pub_type
杂志文章abstract：:Glycosaminoglycans (GAGs) are potent inhibitors of calcium oxalate growth and aggregation. The synthetic GAG pentosan polysulphate (PPS) was used in the treatment of patients with renal calcium stone disease. Altogether, 121 patients were included in an open trial over a 3-year-period. The average stone episode rate a...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/BF00182052
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVES:To characterize testosterone profile changes over time in a cohort of prostate cancer (PCa) patients managed with active surveillance (AS) and to assess its correlation with the initial disease characteristics and further progression. METHODS:We conducted retrospective chart review of PCa patients managed w...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2270-2
更新日期：2018-08-01 00:00:00
abstract：:The funding number was incorrect in the original published article. The correct funding number should read as follows. ...
journal_title：World journal of urology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00345-018-2289-4
更新日期：2018-08-01 00:00:00
abstract：:Gastrin releasing peptide (GRP) is a neuropeptide that has been suggested to play a role in the development of some malignancies. Our aim was: (1) to identify the expression of GRP in cancerous prostate glands, and (2) to correlate its expression to various pathological parameters and to the patient's clinical outcome...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-003-0339-y
更新日期：2003-08-01 00:00:00
abstract：OBJECTIVES:To evaluate retrospectively the objective and subjective parameters in 42 male patients who underwent bone anchored sub-urethral sling positioning (BAUS) for SUI (stress urinary incontinence) due to ISD (intrinsic sphincter deficiency). METHODS:Patients with SUI due to radical retropubic prostatectomy (36 p...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-007-0222-3
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:To analyse whether the reported differences in nodal yield at pelvic lymph node dissection (PLND) for bladder cancer, between two hospitals, are reflected in the survival rates. PATIENTS AND METHODS:We assessed follow-up data of all 174 patients (mean age: 62.7, median follow-up: 3 years) who underwent PLND ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0916-z
更新日期：2013-10-01 00:00:00
abstract：:In this prospective study a comparison of 4-versus 7-MHz transrectal ultrasonography for the detection of prostatic carcinoma is reported. A total of 150 prostates were biopsied due to suspicion of malignancy arising at either digital rectal examination, 4- and/or 7-MHz transrectal ultrasonography, or elevated serum p...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00182174
更新日期：1993-01-01 00:00:00
abstract：:Mycophenolate mofetil (MM) is the ester derivative of mycophenolic acid (MPA), which exerts immunosuppressive activity by inhibiting de novo purine biosynthesis. Following animal models and pilot studies in human renal allograft recipients that confirmed MM's ability to prevent and half rejection episodes, 3 large mul...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00182076
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:Although the role of lymph node dissection (LND) is well defined in many urological settings, uncertainty regarding need for LND still exists for patients with renal cell carcinoma (RCC). The aim of the current review is to highlight the rationale for performing or omitting LND at the time of renal surgery. ME...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-016-1886-3
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:To evaluate histological changes in stenotic urethral tissue post-radiation therapy. Treatment of prostate cancer by radiation therapy carries a risk of off-target injury to the membranous urethra causing urethral stenosis. Limited characterization of post-radiation urethral stenosis exists in the literature. W...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-03031-y
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND/AIM:The effects of printed educational material on cancer screening in women (Pap test and mammography) are well documented and confirmed by several studies. The aim of our study was to evaluate the impact of similar printed educational material on prostate cancer screening by PSA and DRE. MATERIAL AND METH...
journal_title：World journal of urology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00345-008-0258-z
更新日期：2008-08-01 00:00:00
abstract：PURPOSE:We sought the association of preoperative serum total testosterone (tT), hypogonadism, 17β estradiol (E2), and sex hormone-binding globulin (SHBG) with early biochemical recurrence (BCR) after radical prostatectomy (RP). METHODS:Sex steroids were assessed the day before surgery (7-11 a.m.) in a cohort of 605 p...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0856-7
更新日期：2013-04-01 00:00:00
abstract：:We prospectively compared, within the same center and during the same period of time, the perioperative parameters as well as the oncological and functional results of both open retropubic (ORP) and laparoscopic radical prostatectomy (LRP). From September 1999 to September 2001, 162 patients with prostate cancer were ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-002-0306-z
更新日期：2003-05-01 00:00:00
abstract：INTRODUCTION:Natural orifice transluminal endoscopic surgery (NOTES) and laparoendoscopic single-site surgery (LESS) are the next steps in the evolution of laparoscopic surgery, promising reduced morbidity and improved cosmetic result. The inconsistent terminology initially used led to confusion. Understanding the tech...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-012-0899-9
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVES:Recent advances have led to the use of magnetic resonance imaging (MRI) alone or with fusion to transrectal ultrasound (TRUS) images for guiding biopsy of the prostate. Our group sought to develop consensus recommendations regarding MRI-guided prostate biopsy based on currently available literature and exper...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-018-2374-8
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:Neurogenic bladder due to spinal cord injury has significant consequences for patients' health and quality of life. Regular surveillance is required to assess the status of the upper and lower urinary lower urinary tracts and prevent their deterioration. In this review, we examine surveillance techniques in neu...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-018-2345-0
更新日期：2018-10-01 00:00:00
abstract：PURPOSE:To investigate, if and how omitting gadolinium-based contrast agents (GBCA) and dynamic contrast-enhanced imaging (DCE) influences diagnostic accuracy and tumor detection rates of prostate MRI. METHODS:In this retrospective study, 236 patients were included. The results of biparametric (bpMRI) and multiparamet...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2428-y
更新日期：2019-04-01 00:00:00
abstract：:The cost of urethral catheterisation injury (UCI) is significant, but the true incidence of patient care error is difficult to establish in the absence of specific hospital codes recording difficult urethral catheterisation (DUC) and UCI. For many years urologists are familiar passing a non-traumatic hydrophilic guide...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2499-9
更新日期：2019-04-01 00:00:00
abstract：:Although immediate radical cystectomy remains the standard of care for invasive bladder cancer, a large body of international experience from single institutions and cooperative groups has accumulated, suggesting favorable results with bladder-sparing approaches in appropriately selected patients. Modern selective bla...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-006-0114-y
更新日期：2006-11-01 00:00:00
abstract：PURPOSE:To investigate the association between overactive bladder (OAB) and coronary artery disease (CAD) as demonstrated on coronary angiography in patients > 65 years. METHODS:The patients who were > 65 years completed an OAB-V8 form before undergoing coronary angiography at a tertiary care hospital. The presence of...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2098-1
更新日期：2018-01-01 00:00:00
abstract：:Metastasis is the cascade of events involved in the transition of a malignancy from a localized tumor to the establishment of a distant foci. In this review we define the known stages and the factors involved. The multiplicity of steps involved allows many opportunities for therapeutic intervention. Current research h...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00186891
更新日期：1996-01-01 00:00:00
abstract：PURPOSE:To review the United States National Cancer Database (NCDB) from 2004 to 2015 and analyze survival outcomes of invasive non-urachal adenocarcinoma based on treatment modality. METHODS:The NCDB 2004-2015 bladder dataset was queried for adenocarcinoma histology, excluding urachal variant, and limited to patients...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2411-7
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To investigate the effects of onabotulinum toxin type A (Onabot/A) intravesical injections on urinary and sexual function in a group of patients affected by multiple sclerosis (MS). METHODS:We enrolled 31 MS female patients with symptoms of overactive bladder and detrusor overactivity. All patients underwent u...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/s00345-015-1578-4
更新日期：2015-12-01 00:00:00
abstract：:The landscape has dramatically changed for patients seeking treatment for rapid ejaculation. Previously, psychotherapy or behavioral treatment was considered to be the treatment of choice for this troubling sexual dysfunction. Since the early 1990s, an efficacious alternative treatment has emerged-the off-label admini...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-004-0489-6
更新日期：2005-06-01 00:00:00
abstract：:The purpose of this study was to assess possible central side-effects of sildenafil (Viagra) on attention and memory functions. Sildenafil and placebo were administered in young male subjects in a double-blind balanced cross-over design. Behavioral patterns and event-related brain potentials (ERP) were recorded in a s...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/pl00007092
更新日期：2001-02-01 00:00:00
abstract：PURPOSE:Donor and recipient gender influence on post-transplant kidney and patient survival is still controversial, and the literature data do not present unanimous conclusions. The aim of this study was to evaluate the effect of gender disparities between donor and recipient in 963 kidney transplants performed at our ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-013-1137-9
更新日期：2014-06-01 00:00:00
abstract：:Growth and morphogenesis of the prostate involves mesenchymal-epithelial interactions. Transforming growth factor-beta 1 (TGF-beta1) is one growth factor that may play a role in these paracrine interactions. We have localized TGF-beta1 by molecular and immunohistochemical analysis in the developing mouse prostate. Acc...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00191212
更新日期：1995-01-01 00:00:00
abstract：:A once-daily (o.d.) formulation of alfuzosin has recently been developed in order to improve the convenience of dosing and to provide optimal pharmacokinetic coverage over a 24-h period. The results of two double-blind, placebo-controlled phase III studies of similar design that included 983 patients with LUTS that su...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-002-0244-9
更新日期：2002-04-01 00:00:00
abstract：PURPOSE:A paucity of data exists on the insignificant disease potentially suitable for active surveillance (AS) among men with intermediate-risk prostate cancer (PCa). We tried to identify pathologically insignificant disease and its preoperative predictors in men who underwent radical prostatectomy (RP) for intermedia...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1413-3
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:To test the association between family history of prostate cancer (FH) and prostate cancer (PCa) risk in a large screening program in Brazil, as no conclusive study has yet investigated this. METHODS:Between 2004 and 2007, 17,569 men were screened in 231 small municipalities using mobile screening units. Posit...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-012-0904-3
更新日期：2013-10-01 00:00:00
