Abstract：
PURPOSE:To investigate, if and how omitting gadolinium-based contrast agents (GBCA) and dynamic contrast-enhanced imaging (DCE) influences diagnostic accuracy and tumor detection rates of prostate MRI. METHODS:In this retrospective study, 236 patients were included. The results of biparametric (bpMRI) and multiparametric magnetic resonance imaging (mpMRI) were compared using the PI-RADS version 2 scoring system. The distribution of lesions to PIRADS score levels, tumor detection rates, diagnostic accuracy and RoC analysis were calculated and compared to the results of histopathological analysis or 5-year follow-up for benign findings. RESULTS:Omitting DCE changed PI-RADS scores in 9.75% of patients, increasing the number of PI-RADS 3 scores by 8.89% when compared to mpMRI. No change of more than one score level was observed. BpMRI did not show significant differences in diagnostic accuracy or tumor detection rates. (AuC of 0.914 vs 0.917 in ROC analysis). Of 135 prostate carcinomas (PCa), 94.07% were scored identically, and 5.93% were downgraded only from PI-RADS 4 to PI-RADS 3 by bpMRI. All of them were low-grade PCa with Gleason Score 6 or 7a. No changes were observed for PCa ≥ 7b. CONCLUSION:Omitting DCE did not lead to significant differences in diagnostic accuracy or tumor detection rates when using the PI-RADS 2 scoring system. According to these data, it seems reasonable to use a biparametric approach for initial routine prostate MRI. This could decrease examination time and reduce costs without significantly lowering the diagnostic accuracy.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Junker D,Steinkohl F,Fritz V,Bektic J,Tokas T,Aigner F,Herrmann TRW,Rieger M,Nagele Udoi
10.1007/s00345-018-2428-ysubject
Has Abstractpub_date
2019-04-01 00:00:00pages
691-699issue
4eissn
0724-4983issn
1433-8726pii
10.1007/s00345-018-2428-yjournal_volume
37pub_type
杂志文章abstract：INTRODUCTION:Concomitant anti-incontinence surgery at the time of prolapse repair has been a long-debated topic. Still today, there remains no clear answer to this question, although in recent years the literature has become more robust with the addition of more randomized controlled trials. The lifetime risk for women...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-015-1591-7
更新日期：2015-09-01 00:00:00
abstract：:A Persian Gulf War veteran presented to the University Neuro-Urology service for management of severe chronic perineal pain. The overall physical and neurological exam was unremarkable. However, the rectal exam and the urodynamic study revealed a severe pelvic floor dysfunction. A neuro-behavioral approach is recommen...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/pl00007098
更新日期：2001-06-01 00:00:00
abstract：PURPOSE:First robotic-assisted kidney transplants (RAKT) were performed in Germany in 2016. To introduce and establish this method as a routine procedure for patients in transplantation medicine, our 2-year experiences are presented. METHODS:Non-randomized open-label cohort study to compare functional and operative re...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02814-7
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To review the United States National Cancer Database (NCDB) from 2004 to 2015 and analyze survival outcomes of invasive non-urachal adenocarcinoma based on treatment modality. METHODS:The NCDB 2004-2015 bladder dataset was queried for adenocarcinoma histology, excluding urachal variant, and limited to patients...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2411-7
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Chronic intraprostatic inflammation is suspected to play a major role in the pathogenesis of prostate cancer (PCa). Polymorphisms in interleukin-10 (IL-10), a key anti-inflammatory cytokine gene can influence immune response and immune evasion of tumor cells. Its role as an anti-metastatic molecule is also w...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0361-1
更新日期：2009-06-01 00:00:00
abstract：PURPOSE:Testicular torsion is the most concerning underlying cause of acute scrotal pain that can lead to loss of the affected testicle. Whether a torted testicle can be salvaged surgically is directly affected by prompt presentation and diagnosis. This study aims to evaluate the awareness of testicular torsion amongst...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2269-8
更新日期：2018-09-01 00:00:00
abstract：:The orthotopic neobladder has become the preferred method of handling the urinary tract after removal of the bladder in men and women. However, an improved quality of life compared to urinary diversion fails to be realized when voiding dysfunction arises. These difficulties with urination range from retention to incon...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450000146
更新日期：2000-10-01 00:00:00
abstract：OBJECTIVES:We reviewed our patients with pathologic T3b renal cell carcinoma (RCC) to determine which factors influenced survival in this high risk patient group. METHODS:From April 1988 to August 2006, 722 patients underwent nephrectomy for RCC at Vanderbilt University. 128 patients (17%) had T3b disease by 2002 AJCC...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0358-9
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:The efficacy and safety of a novel remotely programmed BetterStim sacral neuromodulation (SNM) system was evaluated in patients with refractory overactive bladder (OAB) in a prospective, controlled, multicenter trial. METHODS:A total of 84 patients referred for SNM therapy from October 2015 to January 2018 wer...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00345-019-02698-7
更新日期：2019-11-01 00:00:00
abstract：PURPOSE:Metastatic renal cell carcinoma (mRCC) represents a significant and rising burden of disease, with rapidly evolving treatment modalities. The role of cytoreductive nephrectomy (CN) is controversial in this setting. As such, London Cancer has pursued a multidisciplinary team (MDT) approach when assessing suitabi...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03107-0
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVES:Squamous cell carcinoma (SCC) of the penis with inguinal lymph node involvement aggravates prognosis and can cause femoral artery bleeding, hemorrhagic shock and even death. The objective of this study is to describe the use of extra-anatomical transobturator bypass graft for femoral artery involvement by me...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0282-z
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:To examine the effect of marital status and gender on stage at diagnosis, tumor grade, treatment type and cancer specific mortality (CSM) in patients with localized renal cell carcinoma (RCC). METHODS:Within Surveillance, Epidemiology, and End Results registry (2001-2013), we identified 57,700 patients with T1...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2082-9
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVES:To place chemoprevention of prostate cancer in current clinical context. METHODS:Review of recently published updates of large, randomized, controlled trials of primary chemoprevention of prostate cancer. RESULTS:With extended post-intervention follow-up, SELECT demonstrated a 17% increased risk of prostat...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-011-0822-9
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:To assess the performance of EAU risk classification in PCa patients according to the biopsy pathway (standard versus MRI guided) and to develop a new, more accurate, targeted biopsy (TB)-based classification. MATERIALS AND METHODS:We included 1345 patients consecutively operated by radical prostatectomy (RP) ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-03053-6
更新日期：2020-10-01 00:00:00
abstract：:Gastrin releasing peptide (GRP) is a neuropeptide that has been suggested to play a role in the development of some malignancies. Our aim was: (1) to identify the expression of GRP in cancerous prostate glands, and (2) to correlate its expression to various pathological parameters and to the patient's clinical outcome...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-003-0339-y
更新日期：2003-08-01 00:00:00
abstract：PURPOSE:For better understanding of urogenital tuberculosis (UGTB), its clinical spectrum and characteristic features need to be evaluated. MATERIALS AND METHODS:One hundred and forty-two cases of UGTB patients were analyzed retrospectively. We considered age, gender, symptoms, and diagnostic procedures. RESULTS:The ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02767-x
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:To propose a new coating to silicone implants using Manganese dioxide. We present bacterial adhesion and proliferation when implants are challenged with Escherichia coli. METHODS:Coated and control silicon implants were placed in two independent subcutaneous pouches in the dorsum of Wistar rats. After skin clo...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02856-x
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:Orchialgia after laproscopic renal surgery has been rarely reported in literature, and gonadal vein ligation is considered the main etiology. Our objective was to study the incidence, intensity and to find out any specific factors that could lead to orchialgia. MATERIALS AND METHODS:All patients planned for la...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0864-7
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Different methods for induction and monitoring of urethral sphincter deficiency were explored in a large animal model. METHODS:Sphincter deficiency was established in female pigs by dilatation and cauterization, and amount and frequencies of voiding were monitored and explored by pad test. Sphincteric closu...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2088-3
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:Few studies have been conducted on the serial evaluation of predictors for recovery of urinary continence (RC) after radical prostatectomy (RP) among same cohort. We developed and validated nomograms to predict immediate (≤1), early (≤3), and late (≤12 months) RC from a contemporary series and compared each nom...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-013-1127-y
更新日期：2014-04-01 00:00:00
abstract：PURPOSE:To critically review and synthesize data of ureteroscopy (URS) in different circumstances that all urologists may encounter during everyday clinical practice, such as pregnancy, obesity, bleeding diathesis, renal stones larger than 2 cm, calyceal diverticula, and kidney malformations. METHODS:According to PRIS...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-014-1345-y
更新日期：2015-02-01 00:00:00
abstract：:Urinary bladder cancer (UBC) ranks ninth in worldwide cancer incidence. It is more frequent in men than in women. We review the main established/proposed factors, both environmental and genetic, associated with bladder cancer etiology and prognosis. Data were extracted from previous reviews and original articles ident...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-007-0168-5
更新日期：2007-06-01 00:00:00
abstract：:The physiological role of dehydroepiandrosterone (DHEA) and DHEA sulphate (DHEAS) is poorly understood. It depends in a large part on their transformation into testosterone and estradiol. The capacity of DHEA as a neurosteroid, the recent discovery of putative specific DHEA receptors on endothelial and vascular smooth...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-003-0367-7
更新日期：2003-11-01 00:00:00
abstract：PURPOSE:The effect of living donor kidney allograft size on recipient outcomes is not well understood. In this study, we sought to investigate the relationship between preoperatively measured donor kidney volume and recipient estimated glomerular filtration rate (eGFR) in living donor kidney transplantation (LDKT). ME...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2595-x
更新日期：2019-09-01 00:00:00
abstract：OBJECTIVES:To evaluate the diagnostic value of 12 core biopsy versus sextant biopsy at different prostatic-specific antigen densities (PSAD). METHODS:We retrospectively analyzed the records of 1,463 patients who underwent transrectal ultrasound-guided prostate biopsies at our institution. 995 patients underwent 12 cor...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-008-0264-1
更新日期：2008-08-01 00:00:00
abstract：:Intratesticular varicocele is a rare condition with a variable clinical and ultrasound presentation. The purpose of this study was to evaluate the grey scale and color Doppler appearances of intratesticular varicocele (ITV). Herein we present seven new cases of intratesticular varicocele. From 2003 to 2005 we evaluate...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-007-0216-1
更新日期：2008-02-01 00:00:00
abstract：:Prostate carcinoma (PCa) displays a wide variety of genetic alterations, versatile expression profiles as well as cell surface markers. Despite this heterogeneity, a common treatment for advanced PCa is androgen deprivation therapy (ADT). ADT targets the androgen receptor-a member of the nuclear receptor superfamily-w...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-011-0792-y
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Prognoses for intermediate-risk prostate cancer (PCa) remain heterogeneous. Improved substratification could optimize treatment and monitoring strategies. The objective was to validate this subclassification in a radical prostatectomy (RP) series. METHODS:Between 2000 and 2011, 4038 patients who underwent R...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-016-1979-z
更新日期：2017-08-01 00:00:00
abstract：INTRODUCTION:The da Vinci Single-Port (SP) platform (Intuitive Surgical Inc, Sunnyvale CA) is a recently approved robotic surgical platform which features several novel modifications from previously available single trocar models including a flexible camera, articulating instruments, and navigator guidance for real-tim...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-019-02898-1
更新日期：2020-04-01 00:00:00
abstract：:We are fortunate that our ability to diagnose the specific adrenal entities that mandate a surgical approach is extremely accurate. The combination of analytical methodology to measure the appropriate adrenocortical and medullary hormone production and the radiology techniques for localization are superb. The manageme...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s003450050103
更新日期：1999-02-01 00:00:00
