Abstract：
:Gastrin releasing peptide (GRP) is a neuropeptide that has been suggested to play a role in the development of some malignancies. Our aim was: (1) to identify the expression of GRP in cancerous prostate glands, and (2) to correlate its expression to various pathological parameters and to the patient's clinical outcome. Using standard immunohistochemistry, we evaluated GRP expression in both biopsy and radical prostatectomy specimens from 30 patients with prostatic adenocarcinomas. GRP was expressed in 18 radical prostatectomy specimens (60%) and in 15 biopsies (50%). There was an association between positive immunoexpression of GRP, relapse ( P=0.029) and advanced tumor stages (i.e. pT3, pT4) ( P=0.049). In the respective biopsies, GRP immunostatus was similar to that observed in the subsequent radical prostatectomy specimens. GRP immunoexpression may be of some value as a diagnostic and prognostic marker. Patients whose pathology specimens demonstrate GRP immunopositivity should be closely monitored, since they appear to be at higher risk of disease progression and relapse.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Constantinides C,Lazaris AC,Haritopoulos KN,Pantazopoulos D,Chrisofos M,Giannopoulos Adoi
10.1007/s00345-003-0339-ykeywords:
subject
Has Abstractpub_date
2003-08-01 00:00:00pages
183-7issue
3eissn
0724-4983issn
1433-8726journal_volume
21pub_type
杂志文章abstract：PURPOSE:Holmium laser enucleation of the prostate (HoLEP) has become a popular alternative to TURP for desobstructive prostate surgery. The prevalence of incidental prostate cancer (iPCa) during surgery varies depending on many preoperative factors. To evaluate whether the surgical procedure itself (HoLEP vs. TURP) inf...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2353-0
更新日期：2018-12-01 00:00:00
abstract：:One of the historic landmarks in urology is the first planned nephrectomy performed in 1869 by Gustav Simon of Heidelberg (1824-1877). In the history of medicine the reflections and considerations of the specialized surgeon reveal distinguished analyses of the "case" and, thus, the beginning of a modern scientific dis...
journal_title：World journal of urology
pub_type： 传,历史文章,杂志文章
doi：10.1007/s003450050125
更新日期：1999-06-01 00:00:00
abstract：PURPOSE:To review current practices in manual bladder washouts (MBW) for haematuria with clot retention, comparing those conducted by a urology unit to other inpatient services. Secondly, to describe a standardised protocol for MBWs. METHODS:Prospective data were collected for patients treated for clot retention, from...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2346-z
更新日期：2018-12-01 00:00:00
abstract：:The 30-45% failure rate after radical cystoprostatectomy mandates that we explore and optimize multimodal therapy to achieve better disease control in these patients. Cisplatin-based multi-agent combination chemotherapy has been used with success in metastatic disease and has therefore also been introduced in patients...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-006-0113-z
更新日期：2006-11-01 00:00:00
abstract：PURPOSE:Data assessing the effectiveness of single-use flexible ureteropyeloscopy (FURS) are limited. This study evaluates and compares single-use FURS with conventional reusable FURS. METHODS:A systematic search using electronic databases (Pubmed and Embase) was performed for studies evaluating single-use FURS in the...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-017-2131-4
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:We aimed to explore the knowledge, attitudes, and practices towards prostate cancer (PCa) risk factors and prevention amongst men living in the southern Italian peninsula. METHODS:We retrospectively reviewed data collected during free preventive visits carried out by the Prevention and Research in Oncology (PR...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2074-9
更新日期：2017-12-01 00:00:00
abstract：:Oxybutynin is a tertiary amine, which undergoes an extensive first-pass metabolism. It has an active metabolite, N-desethyl oxybutynin, and the effect of oral oxybutynin is to a large extent exerted by this metabolite. Oxybutynin has both an antimuscarinic and a direct muscle relaxant effect, and, in addition, local a...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/pl00007103
更新日期：2001-11-01 00:00:00
abstract：PURPOSE:To identify factors predicting the risk of inguinal metastasis in squamous cell carcinoma of the penis. The therapeutic advantages of early lymphadenectomy in squamous cell carcinoma of the penis must be counterbalanced against its post-operative morbidity. Loss to follow up is a major problem in developing cou...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-009-0421-1
更新日期：2010-02-01 00:00:00
abstract：PURPOSE:Lymph node dissection (LND) is not routinely performed during radical nephroureterectomy (RNU) in upper tract urothelial carcinomas (UTUC), and its clinical relevance is unclear. The purpose of the present study was to evaluate the impact of LND on clinical outcomes in a large multicenter series of RNU for UTUC...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-011-0705-0
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVES:The objective of our study was to study trainees' feedback and rating of models for training transurethral resection of bladder lesions (TURBT) and prostate (TURP) during simulation. METHODS:The study was performed during the ''Transurethral resection (TUR) module" at the boot camp held in 2019. Prior to th...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03559-4
更新日期：2021-01-04 00:00:00
abstract：PURPOSE:To evaluate the association between the plant-based content of diet and serum testosterone levels in men from the national health and nutrition examination survey (NHANES) database. MATERIALS AND METHODS:Data on demographics, diet, and testosterone levels was acquired from the NHANES database. Using the food f...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03276-y
更新日期：2020-05-28 00:00:00
abstract：PURPOSE:To explore the role of prostate biopsy core length on prediction of index tumor clinical significance and localization on radical prostatectomy (RP) and time to recurrence, hypothesizing 10-, 10-12-, or > 12-mm minimum core as potential biopsy quality control. METHODS:Assessed 2424 prostate biopsy cores and co...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2242-6
更新日期：2018-07-01 00:00:00
abstract：PURPOSE:To assess oncologic outcomes after salvage radiotherapy (SRT) without androgen deprivation therapy (ADT) in patients with persistently detectable PSA after radical prostatectomy (RT). METHODS:Two hundred and one patients who failed to achieve an undetectable PSA received SRT without ADT. The primary endpoint w...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-013-1214-0
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of adjuvant systemic chemotherapy for locally advanced (pT3-4pN0/xM0) upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS:We retrospectively reviewed the medical records of 109 patients with pT3-4pN0/xM0 UTUC who had undergone radical nephroureterectomy between 1996 and 2013...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2032-6
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:To critically review and synthesize data of ureteroscopy (URS) in different circumstances that all urologists may encounter during everyday clinical practice, such as pregnancy, obesity, bleeding diathesis, renal stones larger than 2 cm, calyceal diverticula, and kidney malformations. METHODS:According to PRIS...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-014-1345-y
更新日期：2015-02-01 00:00:00
abstract：PURPOSE:To evaluate the benefit of an antimicrobial prophylaxis protocol using rectal swab cultures in patients undergoing transrectal ultrasound (TRUS)-guided prostate biopsy in our Veterans Affairs population. METHODS:Between June 1, 2013, and June 1, 2014, we implemented an antimicrobial prophylaxis protocol using ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1571-y
更新日期：2015-12-01 00:00:00
abstract：:Surgery following chemotherapy for treatment of metastatic testis cancer is reserved for partial remissions with localized tumors considered resectable. After primary chemotherapy, about 90% will have teratoma or necrosis and only 10% will have cancer. The concept of two cycles of post operative chemotherapy in this s...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00185671
更新日期：1994-01-01 00:00:00
abstract：:Intratesticular varicocele is a rare condition with a variable clinical and ultrasound presentation. The purpose of this study was to evaluate the grey scale and color Doppler appearances of intratesticular varicocele (ITV). Herein we present seven new cases of intratesticular varicocele. From 2003 to 2005 we evaluate...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-007-0216-1
更新日期：2008-02-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to evaluate the factors affecting the lower urinary tract symptoms (LUTS) related quality of life (QoL) score. METHODS:This retrospective study analyzed 29,123 men who underwent health check-ups from January 2007 to July 2011 at a single institution. Those patients who completed th...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2052-2
更新日期：2017-11-01 00:00:00
abstract：:Can urolithiasis start as an intratubular event? Under severe hyperoxaluric conditions in animal models at least crystal formation can. Recently models have been presented that assess the chances of crystal formation under more normal conditions. These models describe changes in fluid composition as this passes throug...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF01367659
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:The purpose of the study is to introduce our experience of a modified single-port minilaparoscopic technique for the treatment of pediatric hydrocele. METHODS:Between June 2008 and May 2012, 279 boys (115 communicating hydrocele and 164 "non-communicating" hydrocele, diagnosis based on preoperative physical ex...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1259-8
更新日期：2014-12-01 00:00:00
abstract：: ...
journal_title：World journal of urology
pub_type： 社论
doi：10.1007/s00345-019-02659-0
更新日期：2019-02-01 00:00:00
abstract：:Percutaneous nephrolithotomy (PCNL) remains the treatment of choice for staghorn renal calculi. Many reports suggest that laparoscopy can be an alternative treatment for large renal stones. We wished to evaluate the role and feasibility of laparoscopic extended pyelolithotomy (REP) for treatment of staghorn calculi. T...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-006-0099-6
更新日期：2006-06-01 00:00:00
abstract：PURPOSE:To test the association between family history of prostate cancer (FH) and prostate cancer (PCa) risk in a large screening program in Brazil, as no conclusive study has yet investigated this. METHODS:Between 2004 and 2007, 17,569 men were screened in 231 small municipalities using mobile screening units. Posit...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-012-0904-3
更新日期：2013-10-01 00:00:00
abstract：:Many human tumors such as bladder carcinoma that are initially responsive to chemotherapy eventually fail to respond to treatment. For most drugs, dose escalation that may be required for a cure cannot be achieved because sensitive tissues such as bone marrow limit cytotoxic therapy. Approaches to prevent or circumven...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00184246
更新日期：1994-01-01 00:00:00
abstract：:A review of the current literature is conducted to explore the developmental aspects, animal and human experiences and the effects of pharmacological manipulation to explain the role androgens play in sexual function with special emphasis on erectile function and the erectile tissue. This review reveals that androgens...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF01275152
更新日期：1997-01-01 00:00:00
abstract：:Local recurrent prostate cancer after radical treatment is found in the majority of men with a rising PSA. Salvage treatment procedures for recurrent disease, such as radiation therapy and ablative procedures, can provide long-term responses in well-selected cases. Prostate magnetic resonance imaging (MRI) allows diag...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-019-02677-y
更新日期：2019-08-01 00:00:00
abstract：:The cost of urethral catheterisation injury (UCI) is significant, but the true incidence of patient care error is difficult to establish in the absence of specific hospital codes recording difficult urethral catheterisation (DUC) and UCI. For many years urologists are familiar passing a non-traumatic hydrophilic guide...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2499-9
更新日期：2019-04-01 00:00:00
abstract：:Transcutaneous application of low-frequency electric current in the treatment of partially or temporarily denervated striated muscles is widely used to prevent or treat muscular atrophy. Due to the high regenerative capacity of smooth-muscle cells, this approach should be beneficial in the treatment of diseases with s...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF00182971
更新日期：1995-01-01 00:00:00
abstract：:Despite several new urine markers urinary cytology remains the gold standard for the non-invasive detection of bladder carcinoma. The use of monoclonal antibodies against tumor associated antigens offers a promising approach to improve urinary cytology. The aim of this study was to compare fluorescence immunocytology ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-003-0390-8
更新日期：2004-06-01 00:00:00
