Abstract:
:Surgery following chemotherapy for treatment of metastatic testis cancer is reserved for partial remissions with localized tumors considered resectable. After primary chemotherapy, about 90% will have teratoma or necrosis and only 10% will have cancer. The concept of two cycles of post operative chemotherapy in this small group with cancer is supported by a 70% long term cure rate. A more difficult group of patients are those who have had not only primary but also salvage chemotherapy for refractory tumor. About 55% of these patients undergoing post (salvage) chemotherapy RPLND surgery have persistent cancer in the resected specimen. There is no data to support the routine use of repeat salvage chemotherapy post operatively. Of 91 patients presenting for surgery post salvage chemotherapy, 53 were considered completely resected and 36 incompletely resected. Of the 53 realistic candidates for cure with complete resections, 25 were given post operative repeat salvage chemotherapy and 28 received none. 9 (36%) receiving more chemotherapy remained NED and 12 (43%) receiving none remained NED. 12 in each group died of disease. Therefore, there is no data to support routine repeat salvage chemotherapy in patients considered completely resected who had already received salvage chemotherapy pre-operatively. Rather the outcome in this cohort depends more on the completeness of its resectability.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Donohue JP,Fox EP,Williams SD,Loehrer PJ,Ulbright TM,Einhorn LH,Weathers TDdoi
10.1007/BF00185671subject
Has Abstractpub_date
1994-01-01 00:00:00pages
190-5issue
4eissn
0724-4983issn
1433-8726journal_volume
12pub_type
杂志文章,评审abstract:PURPOSE:To assess long-term clinical and oncological outcome in women undergoing radical cystectomy and ileal neobladder reconstruction for invasive bladder cancer. METHODS:From 1995 to 2010, a total of 121 women with clinically organ-confined urothelial carcinoma underwent radical cystectomy with an orthotopic ileal ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0837-x
更新日期:2012-12-01 00:00:00
abstract::Telemedicine is the use of communication technologies to deliver health care. Telesurgical telementoring represents an advanced form of telemedicine, whereby an experienced surgeon can guide and teach practicing surgeons new operative techniques utilizing current video technology, medical robots, and high-band-width t...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s003450050082
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To evaluate temporary double J ureteric stenting (TDJS) as a test to diagnose ureteropelvic junction obstruction (UPJO) in equivocal cases. MATERIALS AND METHODS:One hundred and nine consecutive adult patients with loin pain and ipsilateral equivocal UPJO (EqUPJO) on radioisotope diuretic renogram (RDR) were e...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-009-0464-3
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:To evaluate the opinion of urologists and their audience regarding patient safety and educational value of live surgical demonstrations (LSD) and semi-live surgical demonstrations (semi-LSD). METHODS:Following the '2017 Challenges in Endourology' meeting, a survey addressing patient safety and the educational ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2291-x
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To compare the efficiency and safety of suctioning ureteral access sheath (UAS) and traditional UAS during flexible ureteroscopy (FURS) for treatment of renal stones. METHODS:Between January 2015 and December 2017, 165 patients who had renal stones successfully underwent FURS with suctioning UAS created by con...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2455-8
更新日期:2019-05-01 00:00:00
abstract::Many women develop stress urinary incontinence (SUI) after childbirth, but the exact neuronal changes are largely unknown. This study is designed to identify the neuronal changes associated with pregnancy, delivery and ovariectomy. A total of 10 virgin and 48 pregnant rats were used. Cystometry and stress/sneeze tests...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-004-0444-6
更新日期:2004-10-01 00:00:00
abstract:INTRODUCTION:Adherent perirenal fat (APF) can be defined as inflammatory fat sticking to renal parenchyma, whose dissection is difficult and makes it troublesome to expose the tumour. Our objective was to evaluate the impact of APF on the technical difficulty of robot-assisted partial nephrectomy (RPN). PATIENTS AND M...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1500-0
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:To investigate the association between overactive bladder (OAB) and coronary artery disease (CAD) as demonstrated on coronary angiography in patients > 65 years. METHODS:The patients who were > 65 years completed an OAB-V8 form before undergoing coronary angiography at a tertiary care hospital. The presence of...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2098-1
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To review current practices in manual bladder washouts (MBW) for haematuria with clot retention, comparing those conducted by a urology unit to other inpatient services. Secondly, to describe a standardised protocol for MBWs. METHODS:Prospective data were collected for patients treated for clot retention, from...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2346-z
更新日期:2018-12-01 00:00:00
abstract:INTRODUCTION:Percutaneous stone removal increasingly plays an important role among the different approaches of interventional stone therapy, particularly since the development of miniaturized instruments is resulting in lower morbidity for the patients. One major drawback of smaller instruments is the increased difficu...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1541-4
更新日期:2015-11-01 00:00:00
abstract::Prostate carcinoma (PCa) displays a wide variety of genetic alterations, versatile expression profiles as well as cell surface markers. Despite this heterogeneity, a common treatment for advanced PCa is androgen deprivation therapy (ADT). ADT targets the androgen receptor-a member of the nuclear receptor superfamily-w...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-011-0792-y
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To determine retrospectively the perioperative management and outcome of transurethral prostate/bladder surgery (TURP, TURB) and transrectal prostate biopsy in hemophiliacs. METHODS:Thirty-seven hemophilic patients underwent TURP (12 patients), TURB (13 patients), or transrectal prostate biopsy (12 patients) w...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0988-9
更新日期:2013-06-01 00:00:00
abstract::The diagnosis of prostate cancer (PCa) can be challenging due to the limited performance of current diagnostic tests, including PSA, digital rectal examination and transrectal conventional US. Multiparametric MRI has improved PCa diagnosis and is recommended prior to biopsy; however, mp-MRI does miss a substantial num...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03193-0
更新日期:2020-04-18 00:00:00
abstract:PURPOSE:Patients presenting with prostate gland sizes greater than 200 cc pose a unique surgical challenge to both patients and surgeons. The objective of this study is to critically assess the efficacy and risks associated with performing holmium laser enucleation of the prostate (HoLEP) on glands ≥ 200 cc. MATERIALS...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03156-5
更新日期:2020-03-23 00:00:00
abstract:PURPOSE:To explore the role of prostate biopsy core length on prediction of index tumor clinical significance and localization on radical prostatectomy (RP) and time to recurrence, hypothesizing 10-, 10-12-, or > 12-mm minimum core as potential biopsy quality control. METHODS:Assessed 2424 prostate biopsy cores and co...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2242-6
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate the safety and efficiency of multiple-tract percutaneous nephrolithotomy (PCNL) as a day surgery for the treatment of complex renal stones. PATIENTS AND METHODS: A mature protocol for day surgery was implemented. Forty-six patients who underwent planned day-surgery PCNL...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03260-6
更新日期:2020-05-23 00:00:00
abstract:PURPOSE:To review the recent advances in terms of surgical technique and new robotic platforms applied to radical perineal prostatectomy (RPP). METHODS:A literature review was performed focusing on original articles on perineal prostatectomy searching via Medline/Pubmed and Embase. The entire spectrum was covered such...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-019-03004-1
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Following its introduction in 1980, shock wave lithotripsy (SWL) rapidly emerged as the first-line treatment for the majority of patients with urolithiasis. Millions of SWL therapies have since been performed worldwide, and nowadays, SWL still remains to be the least invasive therapy modality for urinary s...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-014-1369-3
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:Androgen receptor (AR) action in benign and malignant tissue is potentiated by a number of co-regulatory proteins that may interact with one or more receptor domains. With improvement of research methodologies, it became possible to detect a number of co-activators whose expression is increased in prostate c...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-011-0797-6
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVES:To place chemoprevention of prostate cancer in current clinical context. METHODS:Review of recently published updates of large, randomized, controlled trials of primary chemoprevention of prostate cancer. RESULTS:With extended post-intervention follow-up, SELECT demonstrated a 17% increased risk of prostat...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-011-0822-9
更新日期:2012-04-01 00:00:00
abstract:INTRODUCTION:Changes in the management of minimally invasive oncologic renal surgery have introduced ablative therapies as the most recent advancement in minimally invasive technology. METHODS:The current evidence-based medicine on the topic of laparoscopic (LCA) and percutaneous (PCA) renal cryoablation was gathered ...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-010-0552-4
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To provide most recent and high quality evidence concerning the comparison between monopolar and bipolar transurethral resection of non-muscle invasive bladder tumors. MATERIALS AND METHODS:Two researchers performed a systematic review of the current literature independently, to identify studies published in...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03313-w
更新日期:2020-06-26 00:00:00
abstract::Urinary tract infection (UTI) remains the most common type of infection contracted by kidney transplant patients. UTI reduces both patient and graft survival. Understanding and managing UTI in transplant patients requires an appreciation of their unique anatomy and physiology. Both the transplant and native urinary sy...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-019-02742-6
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:Erectile dysfunction (ED) and cardiovascular disease (CVD) share a great number of common risk factors. There is growing evidence that aldosterone, an independent CVD risk factor, is associated with ED. AIMS:The purpose of this study was to determine the relationship between plasma aldosterone and erectil...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1723-0
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Previous studies reported improved outcomes for bladder cancer patients who had radical cystectomy (RC) performed by surgeons and hospitals with high annual RC volumes. The objective of this study was to determine the effect of high hospital and surgeon volume on overall survival after RC fo...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-014-1457-4
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Rectal culture screening for fluoroquinolone (FQ)-resistant Enterobacteriaceae before transrectal ultrasound guided prostate (TRUSPB) biopsy and targeted antibiotic prophylaxis (TAP) may decrease post-TRUSPB infection rates compared to empiric (EAP) regimens. The objective of this study was to evaluate the effe...
journal_title:World journal of urology
pub_type: 杂志文章,meta分析
doi:10.1007/s00345-018-2217-7
更新日期:2018-07-01 00:00:00
abstract::Successful management of transitional-cell carcinoma of the urinary bladder is greatly dependent upon regular surveillance and early detection of persistent or recurrent carcinoma. The development of a highly sensitive urinary test for the detection of transitional-cell carcinoma of the bladder could have a dramatic i...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/BF02201981
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:We aimed to explore the knowledge, attitudes, and practices towards prostate cancer (PCa) risk factors and prevention amongst men living in the southern Italian peninsula. METHODS:We retrospectively reviewed data collected during free preventive visits carried out by the Prevention and Research in Oncology (PR...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2074-9
更新日期:2017-12-01 00:00:00
abstract::Peyronie's disease (PD, induratio penis plastica) is uncommon. Its etiology is unknown and the incidence is stated to be 1%, although more recent data suggest that it is higher. The symptoms are penile deviation and painful erection in association with penile plaques. The diagnosis is performed by palpation of the pen...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-004-0424-x
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:Management of male infertility is always a difficult task, with pathophysiology and available treatments often poorly understood. The purpose of this review was to summarize current evidence regarding the use of protective agents against reactive oxygen species (ROS), such as antioxidants that may be useful in ...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-019-02656-3
更新日期:2019-06-01 00:00:00