Abstract:
:Many women develop stress urinary incontinence (SUI) after childbirth, but the exact neuronal changes are largely unknown. This study is designed to identify the neuronal changes associated with pregnancy, delivery and ovariectomy. A total of 10 virgin and 48 pregnant rats were used. Cystometry and stress/sneeze tests were performed in the virgin once and the pregnant rats at certain time points. Postpartum the rats were equally grouped as follows: group I: delivery, group II: delivery + ballooning, group III: delivery + ovariectomy, group IV: delivery + ballooning + ovariectomy. Tissues from bladder, bladder neck, and urethra were analyzed by immunostaining for PGP 9.5, CGRP, SP, NPY, VIP, TH, n-NOS. We found complex innervation changes in the different tissue samples. Since the bladder neck and the mid-urethra play an important role in the continence mechanism the neuronal changes in these areas contribute to the observed functional changes.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Sievert KD,Bakircioglu ME,Tsai T,Nunes L,Lue TFdoi
10.1007/s00345-004-0444-6keywords:
subject
Has Abstractpub_date
2004-10-01 00:00:00pages
244-50issue
4eissn
0724-4983issn
1433-8726journal_volume
22pub_type
杂志文章abstract:PURPOSE:The lack of precedent in transitioning from pediatric to adult care poses a challenge to providers for patients with spina bifida (SB). The purpose of this study was to summarize perceptions about best practices for the care of adult spina bifida patients. MATERIALS AND METHODS:A national survey was electronic...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02635-8
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:To assess oncologic outcomes after salvage radiotherapy (SRT) without androgen deprivation therapy (ADT) in patients with persistently detectable PSA after radical prostatectomy (RT). METHODS:Two hundred and one patients who failed to achieve an undetectable PSA received SRT without ADT. The primary endpoint w...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-013-1214-0
更新日期:2014-10-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0655-6
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND/AIM:The effects of printed educational material on cancer screening in women (Pap test and mammography) are well documented and confirmed by several studies. The aim of our study was to evaluate the impact of similar printed educational material on prostate cancer screening by PSA and DRE. MATERIAL AND METH...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00345-008-0258-z
更新日期:2008-08-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Reactive oxygen species (ROS) are produced during the interaction between oxalate/calcium oxalate monohydrate (COM) crystals and renal epithelial cells and are responsible for the various cellular responses through the activation of NADPH oxidase (Nox). Ox and COM also activate the renin-ang...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1563-y
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To report our experience with pelvic reconstructive surgery with transobturator mesh implants in elderly women. MATERIALS AND METHODS:A total of 32 women aged >75 years with pelvic organ prolapse receiving anterior and/or posterior repair using transobturator mesh implants were included. Concomitant mid-urethr...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-012-0863-8
更新日期:2013-06-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2274-y
更新日期:2018-08-01 00:00:00
abstract::Vesicoureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. The current indications for the surgical correction of VUR depend on the presence or absence of renal scars. If no scars are present, primary ureteral reimplantation is only indicated in high-grade bil...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-004-0408-x
更新日期:2004-06-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-019-02898-1
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVE:To assess treatments and survival of patients with muscle invasive bladder cancer (MIBC) in the Comprehensive Cancer Center Northern Netherlands (CCCN) region. STUDY DESIGN AND SETTING:Retrospective cohort analysis. Data of 548 patients with MIBC diagnosed between 1997 and 2002 were collected from the CCCN c...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-010-0546-2
更新日期:2010-08-01 00:00:00
abstract::The author presents the life and achievements of Johann von Mikulicz-Radecki and his contribution to European and world surgery. Mikulicz was born in Czernowitz, then a part of the Austro-Hungarian Empire. He was educated in numerous Austrian schools and graduated at Vienna University in 1875. In 1880 he became surgeo...
journal_title:World journal of urology
pub_type: 传,历史文章
doi:10.1007/s00345-007-0227-y
更新日期:2008-02-01 00:00:00
abstract::We are fortunate that our ability to diagnose the specific adrenal entities that mandate a surgical approach is extremely accurate. The combination of analytical methodology to measure the appropriate adrenocortical and medullary hormone production and the radiology techniques for localization are superb. The manageme...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s003450050103
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:To propose a new coating to silicone implants using Manganese dioxide. We present bacterial adhesion and proliferation when implants are challenged with Escherichia coli. METHODS:Coated and control silicon implants were placed in two independent subcutaneous pouches in the dorsum of Wistar rats. After skin clo...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02856-x
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:To evaluate the benefit of an antimicrobial prophylaxis protocol using rectal swab cultures in patients undergoing transrectal ultrasound (TRUS)-guided prostate biopsy in our Veterans Affairs population. METHODS:Between June 1, 2013, and June 1, 2014, we implemented an antimicrobial prophylaxis protocol using ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1571-y
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:The purpose of the study is to introduce our experience of a modified single-port minilaparoscopic technique for the treatment of pediatric hydrocele. METHODS:Between June 2008 and May 2012, 279 boys (115 communicating hydrocele and 164 "non-communicating" hydrocele, diagnosis based on preoperative physical ex...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1259-8
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:Clinical outcomes prognostic markers are awaited in clear-cell renal carcinoma (ccRCC) to improve patient-tailored management and to assess six different markers' influence on clinical outcomes from ccRCC specimen and their incremental value combined with TNM staging. MATERIALS AND METHODS:This is a retrospect...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-016-1854-y
更新日期:2017-01-01 00:00:00
abstract:PURPOSE:Current systemic treatment of targeted therapies, namely the vascular endothelial growth factor-antibody (VEGF-AB), VEGF receptor tyrosine kinase inhibitor (TKI) and mammalian target of rapamycin (mTOR) inhibitors, have improved progression-free survival and replaced non-specific immunotherapy with cytokines in...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-016-1868-5
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:To evaluate renal function and to identify factors associated with renal dysfunction in the elective indications setting of nephron-sparing surgery (NSS). METHODS:We retrospectively reviewed operative data and glomerular filtration rate (GFR) of 519 patients treated by NSS in an elective indications setting be...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-014-1292-7
更新日期:2015-01-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1241-5
更新日期:2014-12-01 00:00:00
abstract::A once-daily (o.d.) formulation of alfuzosin has recently been developed in order to improve the convenience of dosing and to provide optimal pharmacokinetic coverage over a 24-h period. The results of two double-blind, placebo-controlled phase III studies of similar design that included 983 patients with LUTS that su...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-002-0244-9
更新日期:2002-04-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-008-0361-1
更新日期:2009-06-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-016-1830-6
更新日期:2017-01-01 00:00:00
abstract::The purpose of this study was to assess possible central side-effects of sildenafil (Viagra) on attention and memory functions. Sildenafil and placebo were administered in young male subjects in a double-blind balanced cross-over design. Behavioral patterns and event-related brain potentials (ERP) were recorded in a s...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/pl00007092
更新日期:2001-02-01 00:00:00
abstract::The physiological role of dehydroepiandrosterone (DHEA) and DHEA sulphate (DHEAS) is poorly understood. It depends in a large part on their transformation into testosterone and estradiol. The capacity of DHEA as a neurosteroid, the recent discovery of putative specific DHEA receptors on endothelial and vascular smooth...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-003-0367-7
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVES:Molecular targets in cancer diagnosis and therapy have come to the fore of the oncology field in the last decade. Their identification is rooted in basic science investigation and enhanced knowledge in the fields of genetics, biochemistry, molecular and tumor biology, and pathology among others. METHODS:A m...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-008-0339-z
更新日期:2009-02-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2066-9
更新日期:2017-11-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02950-0
更新日期:2020-06-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-013-1099-y
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To present current evidence supporting the vessel sparing technique to reconstruct bulbar urethral strictures via primary anastomosis. METHODS:English literature review of presented series of transecting and non-transecting bulbar urethroplasty from 2000 to 2018. RESULTS:Since its introduction in 2007, vessel...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02867-8
更新日期:2020-12-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-010-0633-4
更新日期:2011-06-01 00:00:00