Abstract：
OBJECTIVES:To place chemoprevention of prostate cancer in current clinical context. METHODS:Review of recently published updates of large, randomized, controlled trials of primary chemoprevention of prostate cancer. RESULTS:With extended post-intervention follow-up, SELECT demonstrated a 17% increased risk of prostate cancer relative to placebo in the vitamin E alone arm. Two other trials in men with high-grade PIN demonstrated no effect of selenium alone or in combination with soy and lycopene. Trials of 5α-reductase inhibitors show an approximate 25% relative risk reduction in men at average risk and in those with an "elevated" PSA and prior negative biopsy, but adoption of these agents in clinical practice has been limited by concerns over an apparently increased risk of high-grade disease. CONCLUSIONS:Primary prevention of prostate cancer remains an attractive goal because of its prevalence and treatment-related morbidity. Neither selenium nor vitamin E prevents prostate cancer. The benefit/risk ratio for 5α-reductase inhibitors can be improved by limiting their use to men at high risk.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Klein EA,Thompson IMdoi
10.1007/s00345-011-0822-9subject
Has Abstractpub_date
2012-04-01 00:00:00pages
189-94issue
2eissn
0724-4983issn
1433-8726journal_volume
30pub_type
杂志文章,评审abstract：BACKGROUND:Dhat syndrome (DS) consists of vague somatic symptoms and at times sexual dysfunction which the patient falsely attributes to involuntary emissions of semen outside of sexual relations. OBJECTIVE:Describe and analyse the occurrences of DS in patients attending the clinic and clarify the existence of this co...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0911-4
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:To assess the long-term patient-reported outcomes following TO-TVT as a secondary continence procedure in women with recurrent stress urinary incontinence (R-SUI). METHODS:A secondary analysis of the 9-year follow-up of the E-TOT study was performed: 341 women with predominant SUI symptoms were randomised to u...
journal_title：World journal of urology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00345-016-1969-1
更新日期：2017-07-01 00:00:00
abstract：INTRODUCTION:Adherent perirenal fat (APF) can be defined as inflammatory fat sticking to renal parenchyma, whose dissection is difficult and makes it troublesome to expose the tumour. Our objective was to evaluate the impact of APF on the technical difficulty of robot-assisted partial nephrectomy (RPN). PATIENTS AND M...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1500-0
更新日期：2015-11-01 00:00:00
abstract：INTRODUCTION:Percutaneous stone removal increasingly plays an important role among the different approaches of interventional stone therapy, particularly since the development of miniaturized instruments is resulting in lower morbidity for the patients. One major drawback of smaller instruments is the increased difficu...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1541-4
更新日期：2015-11-01 00:00:00
abstract：PURPOSE:To evaluate the association between the plant-based content of diet and serum testosterone levels in men from the national health and nutrition examination survey (NHANES) database. MATERIALS AND METHODS:Data on demographics, diet, and testosterone levels was acquired from the NHANES database. Using the food f...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03276-y
更新日期：2020-05-28 00:00:00
abstract：INTRODUCTION AND OBJECTIVES:The possibility of performing remote-surgery has been the goal to achieve, since the early development of the first surgical robotic platforms. This systematic review aims to analyse the state of the art in the field and to provide an overview of the possible growth of this technology. METH...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02996-0
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:Erectile dysfunction (ED) is an early sign of vascular dysfunction. Studies have reported a correlation between arterial stiffness and cardiovascular events. The objective of this study was to evaluate the association among different criteria for assessing arterial stiffness and cardiovascular risk factors in E...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-009-0486-x
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To test the association between family history of prostate cancer (FH) and prostate cancer (PCa) risk in a large screening program in Brazil, as no conclusive study has yet investigated this. METHODS:Between 2004 and 2007, 17,569 men were screened in 231 small municipalities using mobile screening units. Posit...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-012-0904-3
更新日期：2013-10-01 00:00:00
abstract：:The landscape has dramatically changed for patients seeking treatment for rapid ejaculation. Previously, psychotherapy or behavioral treatment was considered to be the treatment of choice for this troubling sexual dysfunction. Since the early 1990s, an efficacious alternative treatment has emerged-the off-label admini...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-004-0489-6
更新日期：2005-06-01 00:00:00
abstract：PURPOSE:To determine whether individual and/or cumulative components of metabolic syndrome (obesity, hypertension, dyslipidemia, and hyperglycemia) are associated with pathologic features of kidney cancer. PATIENTS AND METHODS:A review of our kidney tumor database identified 462 patients who underwent partial or radic...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-016-1850-2
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVE:It has been hypothesized that endothelial dysfunction and pelvic atherosclerosis may contribute to lower urinary tract symptoms (LUTS). We assessed the relationship between cardiovascular risk factors and LUTS severity in male patients presented to urology clinic. METHODS:It is a cross-sectional study on pat...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2432-2
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Numerous recent studies have shown that concomitant carcinoma in situ (CIS) can be closely associated with the prognosis of patients with bladder cancer (BCa). However, the prognostic value of CIS in BCa is still not conclusive. Hence, we performed a systematic review and meta-analysis to explore the associa...
journal_title：World journal of urology
pub_type： 杂志文章,meta分析
doi：10.1007/s00345-019-02738-2
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:Although randomized controlled trials (RCTs) remain the gold standard for determining evidence-based clinical practices, large disease registries that enroll large numbers of patients have become paramount as a relatively cost-effective additional tool. METHODS:We highlight the advantages of disease regis...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-011-0658-3
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:To compare the efficiency and safety of suctioning ureteral access sheath (UAS) and traditional UAS during flexible ureteroscopy (FURS) for treatment of renal stones. METHODS:Between January 2015 and December 2017, 165 patients who had renal stones successfully underwent FURS with suctioning UAS created by con...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2455-8
更新日期：2019-05-01 00:00:00
abstract：: ...
journal_title：World journal of urology
pub_type： 社论
doi：10.1007/s00345-019-02659-0
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Systemic inflammatory response (SIR) plays important roles in initiation, promotion and progression of tumor. However, the prognostic role of preoperative circulating neutrophil-lymphocyte ratio (NLR) (known as a marker of SIR) in human primary bladder cancer (BC) undergoing radical cystectomy (RC) remains c...
journal_title：World journal of urology
pub_type： 杂志文章,meta分析
doi：10.1007/s00345-018-2593-z
更新日期：2019-09-01 00:00:00
abstract：:Familial risks for cancer are important for clinical counseling and understanding cancer etiology. The nationwide Swedish Family-Cancer Database includes all Swedes born in 1932 and later (0 to 68-year-old offspring) with their parents, totaling over 10.2 million individuals. Urological cancer cases were retrieved fro...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-003-0375-7
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:Previous study compared limited number of parameters post the treatment of cold knife and laser urethrotomy for urethral stricture and controversy about the superiority of those two techniques still remains. This study aims to update the evidence and provide better clinical guidance. METHOD:We systematicall...
journal_title：World journal of urology
pub_type： 杂志文章,meta分析
doi：10.1007/s00345-019-02729-3
更新日期：2019-12-01 00:00:00
abstract：:The field of tissue engineering has developed in phases: initially researchers searched for "inert" biomaterials to act solely as replacement structures in the body. Then, they explored biodegradable scaffolds--both naturally derived and synthetic--for the temporary support of growing tissues. Now, a third phase of ti...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-008-0273-0
更新日期：2008-08-01 00:00:00
abstract：OBJECTIVES:We reviewed our patients with pathologic T3b renal cell carcinoma (RCC) to determine which factors influenced survival in this high risk patient group. METHODS:From April 1988 to August 2006, 722 patients underwent nephrectomy for RCC at Vanderbilt University. 128 patients (17%) had T3b disease by 2002 AJCC...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0358-9
更新日期：2009-02-01 00:00:00
abstract：:The effects of pelvic floor muscle contraction on rectal and vesical function were studied in 19 healthy volunteers with the aim of shedding light on some of the hitherto vague aspects of the mechanisms involved in micturition and defecation and their disorders. Rectal and vesical pressures were recorded during pubore...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s003450100218
更新日期：2001-08-01 00:00:00
abstract：PURPOSE:Given that the tumor-promoting inflammation has been previously established in squamous cell carcinoma of the bladder but its contribution to development of urothelial carcinoma (UC) still remains elusive, our aim was to study changes in expression and activity of inflammation-mediating NF-κB and STAT3 transcri...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1237-1
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:The effect of living donor kidney allograft size on recipient outcomes is not well understood. In this study, we sought to investigate the relationship between preoperatively measured donor kidney volume and recipient estimated glomerular filtration rate (eGFR) in living donor kidney transplantation (LDKT). ME...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2595-x
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION:The da Vinci Single-Port (SP) platform (Intuitive Surgical Inc, Sunnyvale CA) is a recently approved robotic surgical platform which features several novel modifications from previously available single trocar models including a flexible camera, articulating instruments, and navigator guidance for real-tim...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-019-02898-1
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:To evaluate the 6-month effects of the recommended drug and light dosage in focal vascular-targeted photodynamic therapy (VTP) using TOOKAD(®) Soluble in patients with localized prostate cancer (LPCa). METHODS:We performed a pooled analysis of 117 men with LPCa, PSA <10 ng/mL, and Gleason score ≤ 7 (3 + 4), fr...
journal_title：World journal of urology
pub_type： 杂志文章,meta分析
doi：10.1007/s00345-015-1505-8
更新日期：2015-07-01 00:00:00
abstract：PURPOSE:Patients and their families utilize online resources when dealing with a diagnosis of bladder cancer. Many patients have questions regarding clinical management options. Online research forums may help researchers and providers identify research areas of interest. Our objective was to review online forums and i...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2479-0
更新日期：2019-06-01 00:00:00
abstract：PURPOSE:To compare the range of reach of our newly designed omni-directional ureteroscope (URF-Y0016), compared to the commonly used URF-P6, FlexX2s, and LithoVue™ scopes, in the upper, middle, and lower calyces in an ex-vivo pyelocaliceal model. METHODS:We fabricated a three-dimensional pyelocaliceal model of the upp...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03151-w
更新日期：2020-03-14 00:00:00
abstract：PURPOSE:To evaluate the efficacy of adjuvant systemic chemotherapy for locally advanced (pT3-4pN0/xM0) upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS:We retrospectively reviewed the medical records of 109 patients with pT3-4pN0/xM0 UTUC who had undergone radical nephroureterectomy between 1996 and 2013...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2032-6
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:Robotic partial nephrectomy (RPN) is a minimally-invasive technique used to treat renal tumors. A clinical pathway and prospective research protocol (AMBU-REIN) were specifically set up to establish and assess the routine use of day-case RPN. METHODS:The AMBU-REIN study was conducted in the framework of the Fr...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03283-z
更新日期：2020-06-08 00:00:00
abstract：PURPOSE:Radical cystectomy (RC) can be associated with significant blood loss. Allogenic blood transfusion (ABT) may alter disease outcome because of a theoretical immunomodulatory effect. We evaluated the effects of ABT on overall survival (OS) and progression-free survival (PFS) of patients undergoing RC for urotheli...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1257-x
更新日期：2014-12-01 00:00:00
