Abstract：
PURPOSE:Although the role of lymph node dissection (LND) is well defined in many urological settings, uncertainty regarding need for LND still exists for patients with renal cell carcinoma (RCC). The aim of the current review is to highlight the rationale for performing or omitting LND at the time of renal surgery. METHODS:Data were identified through a search of PubMed and Web of Science, including studies published in the last 20 years in core clinical journals. The review is based on evidence synthesis from a peer-review process of the two authors after a structured data search. RESULTS:Neither imaging, nor predictive tools or molecular/genetic markers accurately identify which patients may warrant a LND. In patients with clinical T1abN0 and absence of unfavorable clinical and pathological characteristics, LND does not appear to offer benefit in terms of staging and cancer control. Conversely, LND can be considered in selected cases (larger tumors, locally advanced diseases or when unfavorable pathological characteristics are likely, as high Fuhrman grade, sarcomatoid features or tumor necrosis) due to the non-negligible risk of associated nodal metastases and possible benefit in terms of cancer control. CONCLUSIONS:Although LND does not provide any benefit in the majority of RCC cases (mainly T1abN0M0 cases), it remains an important consideration in intermediate-/high-risk patients for staging purposes, given an increased risk of LNI, and for potential benefit in terms of cancer control. Additional data are urgently needed to improve the accuracy of nodal staging tools and to evaluate the potential role of salvage LND.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Capitanio U,Leibovich BCdoi
10.1007/s00345-016-1886-3subject
Has Abstractpub_date
2017-04-01 00:00:00pages
497-506issue
4eissn
0724-4983issn
1433-8726pii
10.1007/s00345-016-1886-3journal_volume
35pub_type
杂志文章,评审abstract：BACKGROUND:The anti-androgen withdrawal syndrome (AAWS) can be seen in one-third of patients after discontinuation of first-generation non-steroidal anti-androgen therapy. With the introduction of new agents for anti-androgen therapy as well as alternate mechanisms of action, new therapeutic options before and after do...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-014-1288-3
更新日期：2014-10-01 00:00:00
abstract：PURPOSE:Salvage radiotherapy (SRT) for biochemical recurrence (BCR) following radical prostatectomy (RP) should if possible be added at a prostate-specific antigen (PSA) level of <1-2 ng/mL. The value of positron emission tomography combined with computed tomography (PET/CT) at such low PSA values is not defined. The p...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-015-1547-y
更新日期：2015-11-01 00:00:00
abstract：:This study examined subjective continence status and use of subsequent alternative therapeutic procedures at long-term follow-up after collagen injection for stress incontinence (SI) in women. Seventy women who underwent collagen injection for SI were identified by retrospective chart review and surveyed by mail quest...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-007-0193-4
更新日期：2007-08-01 00:00:00
abstract：PURPOSE:Urinary cytology (C) and cystoscopy remain the gold standard for the detection and screening of bladder cancer (BC). In this prospective study, we analyzed whether baseline C, ImmunoCyt (I), BTA Stat (B), hemoglobin dipstick (H), and NMP22 BladderChek (N) can predict recurrence and progression. METHODS:Urinary...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/s00345-016-1795-5
更新日期：2016-10-01 00:00:00
abstract：:Our objectives were to ascertain the tolerability and efficacy of trospium chloride in doses of 20 mg twice daily for long-term therapy (52 weeks) in patients with urge syndrome. The trial comprised a total of 358 patients with urge syndrome or urge incontinence. After randomisation in the ratio of 3:1, participants w...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1007/s00345-003-0321-8
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:To introduce the detailed procedures of two innovative surgical options for pediatric buried penis and prospectively compare their efficacy and safety. METHODS:A single-center, non-randomized, prospective study was conducted at the Zhongnan Hospital of Wuhan University, where patients were operated on using...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2243-5
更新日期：2018-08-01 00:00:00
abstract：:The prostatitis syndrome is commonly found in urologic practice and is classified according to the NIDDK/NIH, in which bacterial prostatitis (acute and chronic) is distinguished from chronic pelvic pain syndrome (CPPS). In acute bacterial prostatitis (NIH category I), antibiotic treatment is mandatory and successful i...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-003-0333-4
更新日期：2003-06-01 00:00:00
abstract：PURPOSE:Our objective was to determine the impact of preoperative frailty, as measured by validated Risk Analysis Index (RAI), on the occurrence of postoperative complications after urologic surgeries in a national database comprised of diverse practice groups and cases. STUDY DESIGN:The National Surgical Quality Impr...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-016-1845-z
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVES:Molecular targets in cancer diagnosis and therapy have come to the fore of the oncology field in the last decade. Their identification is rooted in basic science investigation and enhanced knowledge in the fields of genetics, biochemistry, molecular and tumor biology, and pathology among others. METHODS:A m...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-008-0339-z
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:To perform a feasibility phase study of a panel of putative protein biomarkers and determine whether it can identify and predict tumor recurrence in patients with non-muscle-invasive bladder cancer (NMIBC) on follow-up. METHODS:We prospectively analyzed the urine of 152 patients previously treated for NMIBC. Q...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03188-x
更新日期：2020-04-06 00:00:00
abstract：OBJECTIVES:Squamous cell carcinoma (SCC) of the penis with inguinal lymph node involvement aggravates prognosis and can cause femoral artery bleeding, hemorrhagic shock and even death. The objective of this study is to describe the use of extra-anatomical transobturator bypass graft for femoral artery involvement by me...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0282-z
更新日期：2008-10-01 00:00:00
abstract：PURPOSE:In mid-2007, we introduced a new risk-stratified follow-up programme (FUP) for surgically treated localized renal cell carcinoma. After inclusion, the patients have been followed prospectively. In this study, we present the results in regard to stratification, completeness of the FUP and recurrences. METHODS:T...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-016-1796-4
更新日期：2016-08-01 00:00:00
abstract：PURPOSE:The introduction of collagenase Clostridium histolyticum (CCH) has revolutionized the treatment of Peyronie's disease. The efficacy of this therapy has been well demonstrated and the safety profile is favorable. However, post-injection complications are poorly characterized and management of these complications...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-019-02817-4
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Different methods for induction and monitoring of urethral sphincter deficiency were explored in a large animal model. METHODS:Sphincter deficiency was established in female pigs by dilatation and cauterization, and amount and frequencies of voiding were monitored and explored by pad test. Sphincteric closu...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2088-3
更新日期：2017-12-01 00:00:00
abstract：PURPOSE:Vesico-ureteral reflux (VUR) represents one of the most significant risk factors for acute pyelonephritis in children. Surgery is an important part of its management. Laparoscopic ureteric reimplantation using the Lich-Gregoir technique is an option for VUR. The aim of this study is to assess short- and medium-...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2064-y
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:We compared perioperative and long-term renal functional outcomes of robot-assisted partial nephrectomy (RAPN) with laparoscopic partial nephrectomy (LPN) for small renal masses. MATERIALS AND METHODS:A total of 1,032 patients were included for evaluation; propensity score matching was performed to adjust for ...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-015-1488-5
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:The effect of living donor kidney allograft size on recipient outcomes is not well understood. In this study, we sought to investigate the relationship between preoperatively measured donor kidney volume and recipient estimated glomerular filtration rate (eGFR) in living donor kidney transplantation (LDKT). ME...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2595-x
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:To determine retrospectively the perioperative management and outcome of transurethral prostate/bladder surgery (TURP, TURB) and transrectal prostate biopsy in hemophiliacs. METHODS:Thirty-seven hemophilic patients underwent TURP (12 patients), TURB (13 patients), or transrectal prostate biopsy (12 patients) w...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-012-0988-9
更新日期：2013-06-01 00:00:00
abstract：:Due to its unique biological behavior, late relapse (LR) of testicular cancer has recently been described as an own tumor entity. It is currently defined as tumor recurrence more than 2 years after complete remission following primary treatment including chemotherapy. The incidence ranges from 2 to 6%, with a median r...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-004-0397-9
更新日期：2004-04-01 00:00:00
abstract：PURPOSE:Taiwan is a highly endemic area for urothelial carcinoma (UC) and chronic kidney disease (CKD). We evaluate the gender effect on the relationship between renal outcome and clinical characteristics of CKD patients with UC. METHODS:The clinical and pathologic records of 404 patients were retrospectively analyzed...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-011-0682-3
更新日期：2011-08-01 00:00:00
abstract：:We constructed a pubovaginal sling using the Gore-tex Soft Tissue Patch and 2-0 polytetrafluoroethylene (PTFE) suspension suture and placed it in 122 consecutive incontinent women with urethral hypermobility and/or intrinsic sphincter deficiency. We performed a retrospective outcome analysis using a questionnaire-base...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/BF02202014
更新日期：1997-01-01 00:00:00
abstract：:We prospectively compared, within the same center and during the same period of time, the perioperative parameters as well as the oncological and functional results of both open retropubic (ORP) and laparoscopic radical prostatectomy (LRP). From September 1999 to September 2001, 162 patients with prostate cancer were ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-002-0306-z
更新日期：2003-05-01 00:00:00
abstract：:The results of changing treatment modalities in 690 consecutive patients with low stages nonseminomatous germ-cell tumors (NSGCT) of the testis were analyzed. Overall, 120 patients (17.4%) suffered relapses, and 25 (3.6%) died of cancer after a follow-up period ranging from 2 to 20 years. The indications for primary (...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/BF00192265
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:To compare the efficacy, safety, Patient Global Impression of Improvement (PGI-I), and complications rates after 180-W GreenLight laser (180-W GL laser) standard and anatomical photoselective vaporization (sPVP and aPVP). METHODS:Within a multi-institutional database, we identified patients who underwent sPVP ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-017-2106-5
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:To evaluate the feasibility of measuring the intrapelvic pressure (IPP) during f-URS with a wire including a pressure sensor and to assess IPP profiles during the procedure. METHODS:Patients undergoing f-URS for stone disease were recruited. A wire with pressure sensor was placed in the renal cavities to measu...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03216-w
更新日期：2020-05-07 00:00:00
abstract：PURPOSE:To determine whether a delayed percutaneous nephrolithotomy (PCNL) reduces the rate of bacteremia/sepsis in patients with neuromuscular disorders. Patients with neuromuscular disorders are at higher risk of developing complications after PCNL. One strategy to reduce the risk of infectious complications is to pl...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-013-1044-0
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:Assess knowledge and awareness concerning human papillomavirus (HPV) infection, HPV-associated diseases, and the existence of a specific vaccine among non-HPV-screened Caucasian-European adults after the market introduction of HPV vaccines. METHODS:A cohort of 934 consecutive patients seeking their first medic...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-014-1379-1
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To review the etiology and pathogenesis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). METHODS:A literature review for the years 1985-2012 was performed using the MEDLINE database of the United States National Library of Medicine. RESULTS:The evidence for ongoing infection in men with CP/CPPS ...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-013-1061-z
更新日期：2013-08-01 00:00:00
abstract：PURPOSE:To assess the long-term patient-reported outcomes following TO-TVT as a secondary continence procedure in women with recurrent stress urinary incontinence (R-SUI). METHODS:A secondary analysis of the 9-year follow-up of the E-TOT study was performed: 341 women with predominant SUI symptoms were randomised to u...
journal_title：World journal of urology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00345-016-1969-1
更新日期：2017-07-01 00:00:00
abstract：PURPOSE:The use of a ureteral access sheath (UAS) during flexible retrograde intrarenal surgery (RIRS) has become increasingly popular. Our aim was to evaluate the accessibility of a new UAS device, allowing the transformation of the working guidewire into a safety guidewire. METHODS:A prospective, multicenter study w...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-013-1094-3
更新日期：2014-02-01 00:00:00
