Abstract:
PURPOSE:The effect of living donor kidney allograft size on recipient outcomes is not well understood. In this study, we sought to investigate the relationship between preoperatively measured donor kidney volume and recipient estimated glomerular filtration rate (eGFR) in living donor kidney transplantation (LDKT). METHODS:We studied computed tomography (CT) donor kidney volumes and recipient outcomes for 438 LDKTs at the Toronto General Hospital between 2007 and 2016. Estimated glomerular filtration rate (eGFR) was calculated at 1, 3, and 6 months and a multivariable linear regression model was fitted to study the effect of donor kidney volume on recipient eGFR. RESULTS:The mean volume and weight of the donated kidneys were 157.3 (± 32.3) cc and 186.7 (± 48.7) g, respectively. Kidney volume was significantly associated with eGFR on multivariable analysis (P < 0.001). Specifically, for every 10 cc increase in kidney volume, there was a 1.68 mL/min, 1.25 mL/min and 0.97 mL/min rise in recipient eGFR at 1, 3, and 6 months, respectively. CONCLUSIONS:Donor kidney volume is a strong independent predictor of recipient eGFR in LDKT, and therefore, may be a valuable addition to predictive models of eGFR after transplant. Further research may determine if the inclusion of donor kidney volume in matching algorithms can improve recipient outcomes.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Al-Adra DP,Lambadaris M,Barbas A,Li Y,Selzner M,Singh SK,Famure O,Kim SJ,Ghanekar Adoi
10.1007/s00345-018-2595-xsubject
Has Abstractpub_date
2019-09-01 00:00:00pages
1965-1972issue
9eissn
0724-4983issn
1433-8726pii
10.1007/s00345-018-2595-xjournal_volume
37pub_type
杂志文章abstract:PURPOSE:To assess the common practice to transiently place an indwelling transurethral catheter in case of hospitalization of women with febrile urinary tract infections. So far, this intervention has not been scientifically investigated. METHODS:Inclusion criteria were female gender, a leucocyte esterase-positive uri...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
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abstract::Can urolithiasis start as an intratubular event? Under severe hyperoxaluric conditions in animal models at least crystal formation can. Recently models have been presented that assess the chances of crystal formation under more normal conditions. These models describe changes in fluid composition as this passes throug...
journal_title:World journal of urology
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journal_title:World journal of urology
pub_type: 杂志文章,已发布勘误
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journal_title:World journal of urology
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abstract::A Persian Gulf War veteran presented to the University Neuro-Urology service for management of severe chronic perineal pain. The overall physical and neurological exam was unremarkable. However, the rectal exam and the urodynamic study revealed a severe pelvic floor dysfunction. A neuro-behavioral approach is recommen...
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journal_title:World journal of urology
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journal_title:World journal of urology
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journal_title:World journal of urology
pub_type: 杂志文章
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更新日期:2018-07-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02647-4
更新日期:2019-10-01 00:00:00
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pub_type: 杂志文章,已发布勘误
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更新日期:2020-06-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03559-4
更新日期:2021-01-04 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2074-9
更新日期:2017-12-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
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journal_title:World journal of urology
pub_type: 杂志文章
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journal_title:World journal of urology
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journal_title:World journal of urology
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journal_title:World journal of urology
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journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s003450050115
更新日期:1999-04-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章
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journal_title:World journal of urology
pub_type: 杂志文章,评审
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journal_title:World journal of urology
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更新日期:2020-11-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章,meta分析
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更新日期:2020-01-01 00:00:00
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journal_title:World journal of urology
pub_type: 杂志文章,评审
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更新日期:2020-07-30 00:00:00