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Effects of magnesium citrate and phytin on reducing urinary calcium excretion in rats.

Abstract：

:The aim of this study was to determine and compare the effects of both magnesium citrate and phytin on reducing urinary calcium excretion under high-calcium-diet conditions during single and combined treatments. An animal experiment was carried out over a period of 4 weeks in 35 male rats. Urinary calcium excretion was reduced significantly by magnesium citrate and/or phytin in rats fed on high-calcium diets. The hypocalciuric effect of magnesium citrate was more evident than that of phytin. Urinary magnesium excretion was high in all experimental groups. However, the urinary magnesium/calcium ratios showed a consistent increase only in the groups treated with magnesium citrate. Urinary citrate excretion showed a relative increase with the introduction of magnesium citrate plus phytin; however, in both the high-calcium-diet group and the magnesium-citrate group this was found to be reduced. Urinary phosphate excretion was slightly higher in the groups treated with phytin. There was no definite difference in urinary oxalate concentration between the groups. No significant change was noted in the serum concentration of calcium, magnesium, or phosphate.

journal_name

World J Urol

journal_title

World journal of urology

authors

Wu N,Thon WF,Krah H,Schlick R,Jonas U

doi

10.1007/BF00184113

subject

Has Abstract

pub_date

1994-01-01 00:00:00

pages

323-8

issue

6

eissn

0724-4983

issn

1433-8726

journal_volume

12

pub_type

杂志文章

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