Abstract：
:Due to its unique biological behavior, late relapse (LR) of testicular cancer has recently been described as an own tumor entity. It is currently defined as tumor recurrence more than 2 years after complete remission following primary treatment including chemotherapy. The incidence ranges from 2 to 6%, with a median relapse-free interval of 5.4-7.1 years from the initial treatment. Although histology shows a germ cell tumor (GCT) origin, the clinical biology is different. The dominant characteristics are slow tumor growth and chemoresistance. Molecular analysis currently focuses on the mechanisms of drug resistance. The initial response to chemotherapy is less than 30% and in most cases complete surgical resection remains the only treatment option with favorable long-term results. The most common site of LR is the retroperitoneum, with undifferentiated cancer (yolk sac) being the most frequent histology. In most cases, patients have already undergone previous retroperitoneal surgery. The overall cure rate is only about 50%, hence, adequate treatment of the primary tumor is essential to prevent the development of LR.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Lipphardt ME,Albers Pdoi
10.1007/s00345-004-0397-9keywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
47-54issue
1eissn
0724-4983issn
1433-8726journal_volume
22pub_type
杂志文章,评审abstract：PURPOSE:To evaluate for the first time the prognostic significance of female invasive patterns in stage pT4a urothelial carcinoma of the bladder in a large series of women undergoing anterior pelvic exenteration. PATIENTS AND METHODS:Our series comprised of 92 female patients in total of whom 87 with known invasion pa...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-014-1308-3
更新日期：2015-03-01 00:00:00
abstract：:The treatment of clinically locally advanced prostate cancer (cT3-4) is subject to controversies. Patients with lymph node metastases as well as patients with overstaged localized and thus curable disease fall into this category. Radical prostatectomy, external beam radiotherapy and early or deferred hormonal therapy ...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-007-0158-7
更新日期：2007-04-01 00:00:00
abstract：INTRODUCTION:Currently, osteoporosis research is rarely undertaken in males but an increase in male life expectancy in the company of hypogonadism suggests the necessity for potential therapeutic options. MATERIALS AND METHODS:In this study, the changes in bone structure under standardized testosterone- (T), raloxifen...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-009-0373-5
更新日期：2009-08-01 00:00:00
abstract：PURPOSE:To determine the impact of intraoperative ultrasound on robotic-assisted radical nephrectomy with inferior vena cava (IVC) tumor thrombectomy in renal cell carcinoma (RCC). METHODS:We retrospectively analyzed intraoperative records of 27 patients with RCC and invasion of the IVC who underwent robotic-assisted ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03141-y
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To assess the impact of prolonged catheterization time on 1-week (short-term), 3-month (intermediate-term) and 1-year (long-term) UC. METHODS:Between 2008 and 2015, 6918 men underwent RP by four high-volume surgeons. Exclusion criteria were baseline urinary incontinence (UI) and radiotherapy prior or within 12...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2274-y
更新日期：2018-08-01 00:00:00
abstract：:The prostatitis syndrome is commonly found in urologic practice and is classified according to the NIDDK/NIH, in which bacterial prostatitis (acute and chronic) is distinguished from chronic pelvic pain syndrome (CPPS). In acute bacterial prostatitis (NIH category I), antibiotic treatment is mandatory and successful i...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-003-0333-4
更新日期：2003-06-01 00:00:00
abstract：:Glycosaminoglycans (GAGs) are potent inhibitors of calcium oxalate growth and aggregation. The synthetic GAG pentosan polysulphate (PPS) was used in the treatment of patients with renal calcium stone disease. Altogether, 121 patients were included in an open trial over a 3-year-period. The average stone episode rate a...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/BF00182052
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:To evaluate contemporary international trends in the implementation of minimally invasive adrenalectomy and to assess contemporary outcomes of different minimally invasive techniques performed at urologic centers worldwide. METHODS:A retrospective multinational multicenter study of patients who underwent min...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-016-1791-9
更新日期：2016-10-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03260-6
更新日期：2020-05-23 00:00:00
abstract：PURPOSE:To test the association between family history of prostate cancer (FH) and prostate cancer (PCa) risk in a large screening program in Brazil, as no conclusive study has yet investigated this. METHODS:Between 2004 and 2007, 17,569 men were screened in 231 small municipalities using mobile screening units. Posit...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-012-0904-3
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:Patients and their families utilize online resources when dealing with a diagnosis of bladder cancer. Many patients have questions regarding clinical management options. Online research forums may help researchers and providers identify research areas of interest. Our objective was to review online forums and i...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2479-0
更新日期：2019-06-01 00:00:00
abstract：:The aim of this study was to determine the long-term clinical efficacy and complications of neuromodulation with a unilateral sacral foramen electrode in 36 patients with chronic voiding dysfunction. Following a positive effect of a percutaneous nerve evaluation test, patients underwent open surgery. A permanent elect...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s003450050074
更新日期：1998-01-01 00:00:00
abstract：:The aim of this cross-sectional study was to compare single with repeated high-intensity focused ultrasound (HIFU) treatment in patients with localized prostate cancer, regarding treatment-related morbidity. A number of 223 consecutive patients with localized prostate cancer were treated with HIFU. Among them, 174 (78...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-006-0107-x
更新日期：2006-11-01 00:00:00
abstract：PURPOSE:The use of a ureteral access sheath (UAS) during flexible retrograde intrarenal surgery (RIRS) has become increasingly popular. Our aim was to evaluate the accessibility of a new UAS device, allowing the transformation of the working guidewire into a safety guidewire. METHODS:A prospective, multicenter study w...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-013-1094-3
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:The international meeting on reconstructive Urology (IMORU) is a live surgery event (LSE) where expert surgeons perform various reconstructive surgeries. To evaluate patient safety, an extended follow-up of the complications of two subsequent IMORU meetings were gathered. Also, a detailed survey concerning the ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02666-1
更新日期：2019-11-01 00:00:00
abstract：OBJECTIVES:To assess the impact of surgical approaches and clinico-pathological parameters on the prognosis of localized renal cell carcinoma (RCC) after laparoscopic radical nephrectomy (LRN) or open radical nephrectomy (ORN). METHODS:Between 2002 and 2008, 336 patients with localized RCC were treated at our two inst...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-009-0487-9
更新日期：2010-06-01 00:00:00
abstract：:Recent investigations have given a clearer insight into the genetic progression of bladder cancer. In this review we identify the clinical courses of bladder cancer, review the basic concepts of carcinogenesis, and focus on the specific cytogenetic and molecular alterations observed in bladder cancer. Progression mode...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/BF00184243
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:First robotic-assisted kidney transplants (RAKT) were performed in Germany in 2016. To introduce and establish this method as a routine procedure for patients in transplantation medicine, our 2-year experiences are presented. METHODS:Non-randomized open-label cohort study to compare functional and operative re...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02814-7
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To examine phosphodiesterase type 5 (PDE5) expression in the anterior fibromuscular stroma (AFMS) of the prostate. Although PDE5 expression was identified in the human prostate, differences in PDE5 expression in intra-prostatic regions are unknown. The AFMS in the prostate has peculiar innervations that could c...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03095-1
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:To investigate the effects of onabotulinum toxin type A (Onabot/A) intravesical injections on urinary and sexual function in a group of patients affected by multiple sclerosis (MS). METHODS:We enrolled 31 MS female patients with symptoms of overactive bladder and detrusor overactivity. All patients underwent u...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/s00345-015-1578-4
更新日期：2015-12-01 00:00:00
abstract：PURPOSE:To investigate transient receptor potential vanilloid 4 (TRPV4) expression and the effects of ruthenium red (RR)-TRPV antagonist-on detrusor overactivity (DO) associated with bladder outlet obstruction (BOO). METHODS:Rats were randomly assigned to 3 groups. The control group (n = 10) included sham-operated rat...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-013-1099-y
更新日期：2014-06-01 00:00:00
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journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-019-02782-y
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:The anti-androgen withdrawal syndrome (AAWS) can be seen in one-third of patients after discontinuation of first-generation non-steroidal anti-androgen therapy. With the introduction of new agents for anti-androgen therapy as well as alternate mechanisms of action, new therapeutic options before and after do...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-014-1288-3
更新日期：2014-10-01 00:00:00
abstract：:The cost of urethral catheterisation injury (UCI) is significant, but the true incidence of patient care error is difficult to establish in the absence of specific hospital codes recording difficult urethral catheterisation (DUC) and UCI. For many years urologists are familiar passing a non-traumatic hydrophilic guide...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-018-2499-9
更新日期：2019-04-01 00:00:00
abstract：PURPOSE:To assess oncologic outcomes after salvage radiotherapy (SRT) without androgen deprivation therapy (ADT) in patients with persistently detectable PSA after radical prostatectomy (RT). METHODS:Two hundred and one patients who failed to achieve an undetectable PSA received SRT without ADT. The primary endpoint w...
journal_title：World journal of urology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00345-013-1214-0
更新日期：2014-10-01 00:00:00
abstract：INTRODUCTION:Changes in the management of minimally invasive oncologic renal surgery have introduced ablative therapies as the most recent advancement in minimally invasive technology. METHODS:The current evidence-based medicine on the topic of laparoscopic (LCA) and percutaneous (PCA) renal cryoablation was gathered ...
journal_title：World journal of urology
pub_type： 杂志文章,评审
doi：10.1007/s00345-010-0552-4
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To describe results of a simplified technique to configure the vesicourethral anastomosis and to restore posterior musculofascial plate during laparoscopic radical prostatectomy with a "single knot-single running" suture. METHODS:Between December 2006 and 2009, a conventional Van Velthoven anastomosis (group A...
journal_title：World journal of urology
pub_type： 临床试验,杂志文章
doi：10.1007/s00345-012-0840-2
更新日期：2012-10-01 00:00:00
abstract：INTRODUCTION:Herein, current developments in open and minimally invasive renal surgery are presented. MATERIALS AND METHODS:This also includes considerations on the appropriate indication for the two surgical procedures in small renal tumours, locally advanced disease (>pT2), complicated renal tumours as well as cytor...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-008-0238-3
更新日期：2008-04-01 00:00:00
abstract：PURPOSE:To perform a feasibility phase study of a panel of putative protein biomarkers and determine whether it can identify and predict tumor recurrence in patients with non-muscle-invasive bladder cancer (NMIBC) on follow-up. METHODS:We prospectively analyzed the urine of 152 patients previously treated for NMIBC. Q...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03188-x
更新日期：2020-04-06 00:00:00
abstract：INTRODUCTION:The "trifecta" is a summary measure of outcome after partial nephrectomy (PN) that encompasses three parameters: negative surgical margin, ≤ 10% decrease in post-operative estimated glomerular filtration rate (eGFR) and absence of urological complications. We assessed trifecta rates in patients undergoing ...
journal_title：World journal of urology
pub_type： 杂志文章
doi：10.1007/s00345-020-03349-y
更新日期：2020-07-12 00:00:00
