Abstract:
:Recent investigations have given a clearer insight into the genetic progression of bladder cancer. In this review we identify the clinical courses of bladder cancer, review the basic concepts of carcinogenesis, and focus on the specific cytogenetic and molecular alterations observed in bladder cancer. Progression models to superficial and invasive disease are discussed.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Simoneau AR,Jones PAdoi
10.1007/BF00184243subject
Has Abstractpub_date
1994-01-01 00:00:00pages
89-95issue
2eissn
0724-4983issn
1433-8726journal_volume
12pub_type
杂志文章,评审abstract:PURPOSE:To present current evidence supporting the vessel sparing technique to reconstruct bulbar urethral strictures via primary anastomosis. METHODS:English literature review of presented series of transecting and non-transecting bulbar urethroplasty from 2000 to 2018. RESULTS:Since its introduction in 2007, vessel...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02867-8
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:It was our aim in this study to develop a technique that is rather simple, overcomes the problems of Devine and Horton glanuloplasty in patients with small glans, and is flexible to be tailored to any hypospadias surgery. METHODS:A total of 11 patients were included in this preliminary report. A triangular ski...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-009-0386-0
更新日期:2009-10-01 00:00:00
abstract:PURPOSE:The introduction of robotic surgical technology into urological reconstruction, particularly pediatrics, has introduced new horizons for reducing the morbidity and enhancing the efficacy of surgical repair of congenital conditions in children. In reviewing the evolution of pediatric urological applications of r...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-02753-3
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:Squamous cell carcinoma (SCC) of the penis with inguinal lymph node involvement aggravates prognosis and can cause femoral artery bleeding, hemorrhagic shock and even death. The objective of this study is to describe the use of extra-anatomical transobturator bypass graft for femoral artery involvement by me...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-008-0282-z
更新日期:2008-10-01 00:00:00
abstract:PURPOSE:To evaluate the still controversially discussed prognostic role of preoperative platelet level (PPL) and thrombocytosis (TC) in patients who undergo surgery for renal cell carcinoma (RCC) based on the largest patient series reported to date. METHODS:A total of 3,139 patients, who underwent radical or nephron-s...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-012-0931-0
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:We hypothesized that a relevant number of patients with clinically high-risk prostate cancer (PCA) indeed harbor overall favorable tumor characteristics (OFTC) (i.e., pT2a-c and Gleason score ≤3 + 4 = 7 and pN0/X) and that in these patients radical prostatectomy (RP) alone is most likely curative. METHODS:Betw...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1274-9
更新日期:2015-01-01 00:00:00
abstract::The most important phosphates involved in urinary stone disease are carbonate apatite, brushite, and struvite. Overall, phosphate stones account for 12-20% of all stones, with a downward trend for struvite and an increase in carbonate apatite being observed in the last decade. The physicochemical basis for the formati...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s003450050152
更新日期:1999-10-01 00:00:00
abstract:PURPOSE:Prostate cancer (PCa) is the most common malignancy in men and the cause for the second most common cancer-related death in the western world. Despite ongoing development of novel approaches such as second generation androgen receptor targeted therapies, metastatic disease is still fatal. In PCa, immunotherapy ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03497-1
更新日期:2020-10-26 00:00:00
abstract:PURPOSE:To examine phosphodiesterase type 5 (PDE5) expression in the anterior fibromuscular stroma (AFMS) of the prostate. Although PDE5 expression was identified in the human prostate, differences in PDE5 expression in intra-prostatic regions are unknown. The AFMS in the prostate has peculiar innervations that could c...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03095-1
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:The purpose of the study is to introduce our experience of a modified single-port minilaparoscopic technique for the treatment of pediatric hydrocele. METHODS:Between June 2008 and May 2012, 279 boys (115 communicating hydrocele and 164 "non-communicating" hydrocele, diagnosis based on preoperative physical ex...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1259-8
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the impact of age, stone size, location, radiolucency, extraction of stone fragments, size of ureteroscope and presence and degree of hydronephrosis on the efficacy and safety of holmium:YAG (Ho:YAG) laser lithotripsy in the ureteroscopic treatment of ureteral stones in children. METHODS:Between...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-013-1152-x
更新日期:2014-08-01 00:00:00
abstract::Tissue engineering, long a matter of myth and dream throughout the history of medicine, is now a practical reality. A wide spectrum of biological materials are used in the field of urology to treat disease and to overcome human disabilities, including tissue grafts and organ transplantation. Laboratory-engineered biop...
journal_title:World journal of urology
pub_type: 历史文章,杂志文章
doi:10.1007/s003450050015
更新日期:2000-02-01 00:00:00
abstract:PURPOSE:Clear cell, papillary cell, and chromophobe renal cell carcinomas (RCCs) have now been well characterised thanks to large collaborative projects such as The Cancer Genome Atlas (TCGA). Not only has knowledge of the genomic landscape helped inform the development of new drugs, it also promises to fine tune progn...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-018-2429-x
更新日期:2018-12-01 00:00:00
abstract::We prospectively compared, within the same center and during the same period of time, the perioperative parameters as well as the oncological and functional results of both open retropubic (ORP) and laparoscopic radical prostatectomy (LRP). From September 1999 to September 2001, 162 patients with prostate cancer were ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-002-0306-z
更新日期:2003-05-01 00:00:00
abstract::In multivariate analysis, GS of the regular prostatectomy specimen was the only statistically significant parameter for pT2R1 prostate cancer. ...
journal_title:World journal of urology
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00345-020-03136-9
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:Salvage radiotherapy (SRT) for biochemical recurrence (BCR) following radical prostatectomy (RP) should if possible be added at a prostate-specific antigen (PSA) level of <1-2 ng/mL. The value of positron emission tomography combined with computed tomography (PET/CT) at such low PSA values is not defined. The p...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-015-1547-y
更新日期:2015-11-01 00:00:00
abstract::Urinary bladder cancer (UBC) ranks ninth in worldwide cancer incidence. It is more frequent in men than in women. We review the main established/proposed factors, both environmental and genetic, associated with bladder cancer etiology and prognosis. Data were extracted from previous reviews and original articles ident...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-007-0168-5
更新日期:2007-06-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of adjuvant systemic chemotherapy for locally advanced (pT3-4pN0/xM0) upper tract urothelial carcinoma (UTUC). MATERIALS AND METHODS:We retrospectively reviewed the medical records of 109 patients with pT3-4pN0/xM0 UTUC who had undergone radical nephroureterectomy between 1996 and 2013...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2032-6
更新日期:2017-10-01 00:00:00
abstract:PURPOSE:We compared perioperative and long-term renal functional outcomes of robot-assisted partial nephrectomy (RAPN) with laparoscopic partial nephrectomy (LPN) for small renal masses. MATERIALS AND METHODS:A total of 1,032 patients were included for evaluation; propensity score matching was performed to adjust for ...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-015-1488-5
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVES:To place chemoprevention of prostate cancer in current clinical context. METHODS:Review of recently published updates of large, randomized, controlled trials of primary chemoprevention of prostate cancer. RESULTS:With extended post-intervention follow-up, SELECT demonstrated a 17% increased risk of prostat...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-011-0822-9
更新日期:2012-04-01 00:00:00
abstract::The thin mucus or glycosaminoglycan layer of the bladder may be implicated in the pathogenesis of many bladder disease states. We have developed a specific antimucus, antisera stabilization technique to study the ultrastructural morphological appearance of the layer in both normal and abnormal bladders that should pro...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00182045
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:Lymph node dissection (LND) is not routinely performed during radical nephroureterectomy (RNU) in upper tract urothelial carcinomas (UTUC), and its clinical relevance is unclear. The purpose of the present study was to evaluate the impact of LND on clinical outcomes in a large multicenter series of RNU for UTUC...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-011-0705-0
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:Combination therapy of male lower urinary tract symptoms with α(1)-adrenoceptor and muscarinic receptor antagonists attracts increasing interest. Propiverine is a muscarinic receptor antagonist possessing additional properties, i.e., block of L-type Ca(2+) channels. Here, we have investigated whether propiverin...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0655-6
更新日期:2011-04-01 00:00:00
abstract:PURPOSE:XPA-210 is a proliferation marker derived from Thymidine kinase-1. It is of clinical significance in kidney, breast, and bladder cancer. There are no data available for XPA-210 in prostate cancer (PC). Herein, we aim to determine the clinical usefulness of XPA-210 in PC. MATERIALS AND METHODS:In a retrospectiv...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0768-y
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:To examine the effect of marital status and gender on stage at diagnosis, tumor grade, treatment type and cancer specific mortality (CSM) in patients with localized renal cell carcinoma (RCC). METHODS:Within Surveillance, Epidemiology, and End Results registry (2001-2013), we identified 57,700 patients with T1...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2082-9
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:To evaluate the diagnostic potential of choline measurements by in vivo magnetic resonance spectroscopy (MR spectroscopy) for diagnosis of renal masses. METHODS:Twenty-eight patients with 29 renal lesions underwent prospectively preoperative 3 T MR spectroscopy of renal masses before diagnostic tissue confirma...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1272-y
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To explore the role of prostate biopsy core length on prediction of index tumor clinical significance and localization on radical prostatectomy (RP) and time to recurrence, hypothesizing 10-, 10-12-, or > 12-mm minimum core as potential biopsy quality control. METHODS:Assessed 2424 prostate biopsy cores and co...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2242-6
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To evaluate the association between the plant-based content of diet and serum testosterone levels in men from the national health and nutrition examination survey (NHANES) database. MATERIALS AND METHODS:Data on demographics, diet, and testosterone levels was acquired from the NHANES database. Using the food f...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03276-y
更新日期:2020-05-28 00:00:00
abstract:PURPOSE:MicroRNAs (miRNAs) play an important role as regulators of gene expression in tumourigenesis by controlling many biological processes in growth, development, differentiation and apoptosis. Previous studies have shown an altered expression of specific miRNAs in clear cell renal cell carcinoma (ccRCC). But the fu...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-010-0633-4
更新日期:2011-06-01 00:00:00
abstract::This review paper highlights the important health issue of orchialgia and the chronic pelvic pain syndrome. There are a number of specific and non-specific etiologies and different treatment options based on the sub-categorization of orchialgia. The focus of this article is on the specific etiologies of chronic orchia...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-013-1092-5
更新日期:2013-08-01 00:00:00