Changing concepts in the surgery of renal cell carcinoma.

Abstract:

INTRODUCTION:Herein, current developments in open and minimally invasive renal surgery are presented. MATERIALS AND METHODS:This also includes considerations on the appropriate indication for the two surgical procedures in small renal tumours, locally advanced disease (>pT2), complicated renal tumours as well as cytoreductive surgical situations. In small renal tumours, similar survival rates have been described for laparoscopic radical and partial nephrectomy. However, even experienced high volume laparoscopic centres report a high learning curve, increased complications and initial technical problems to achieve parenchymal haemostasis and renal ischaemia during nephron-sparing surgery. Surgical management of large (>T2) or complicated tumours is feasible, but long-term oncological outcome is not yet available. CONCLUSION:Promising new developments such as natural orifice translumenal endoscopic surgery (NOTES) might add to our surgical armamentarium for minimally invasive surgery.

journal_name

World J Urol

journal_title

World journal of urology

authors

Merseburger AS,Kuczyk MA

doi

10.1007/s00345-008-0238-3

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

127-33

issue

2

eissn

0724-4983

issn

1433-8726

journal_volume

26

pub_type

杂志文章
  • Molecular predictors of response to PD-1/PD-L1 inhibition in urothelial cancer.

    abstract:INTRODUCTION:The survival of patients with metastatic urothelial cancer (mUC) is poor. During the last 40 years, chemotherapy was the predominant treatment modality for mUC. The discovery of the immune checkpoint inhibitors (ICI), especially the inhibitors of the programmed cell death 1 and its ligand (PD-1/PD-L1), has...

    journal_title:World journal of urology

    pub_type: 杂志文章,评审

    doi:10.1007/s00345-018-2538-6

    authors: Stühler V,Maas JM,Bochem J,da Costa IA,Todenhöfer T,Stenzl A,Bedke J

    更新日期:2019-09-01 00:00:00

  • The BET-inhibitor PFI-1 diminishes AR/AR-V7 signaling in prostate cancer cells.

    abstract:OBJECTIVE:The bromodomain and extra-terminal (BET) family of proteins provides a scaffolding platform for the recruitment and tethering of transcription factors to acetylated chromatin, thereby modulating gene expression. In this study, we evaluated the efficacy of the BET-inhibitor PFI-1 to diminish AR/AR-V7 signaling...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-018-2382-8

    authors: Hupe MC,Hoda MR,Zengerling F,Perner S,Merseburger AS,Cronauer MV

    更新日期:2019-02-01 00:00:00

  • Local antiseptic therapy for non-gonococcal urethritis: phase II study with Instillagel.

    abstract::Non-gonococcal urethritis (NGU) is conventionally treated with oral antibiotics. With this Phase II study, we investigated the action of a locally disinfecting substance, Instillagel, in symptomatic NGU. Instillation treatment was performed twice daily to 32 male patients with symptomatic NGU. To evaluate the therapeu...

    journal_title:World journal of urology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00345-001-0236-1

    authors: Sperling H,Bastian HP,Boeminghau F,Ludwig G,Terhorst B,Rübben H

    更新日期:2002-05-01 00:00:00

  • Microcirculatory effects of sildenafil in experimental testicular torsion in rats.

    abstract:PURPOSE:Investigate the short-term effect of sildenafil on microcirculation, especially the velocity, the pattern of the flow and the recruitment of the leukocyte in postcapillaries. METHODS:In male Sprague-Dawley rats, the microcirculatory consequences of 60 min experimental testicular torsion, followed by 240 min of...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-018-2340-5

    authors: Oroszi M,Szabó A,Fehér ÁM,Deák G,Bajory Z

    更新日期:2018-12-01 00:00:00

  • Preoperative frailty predicts postoperative complications and mortality in urology patients.

    abstract:PURPOSE:Our objective was to determine the impact of preoperative frailty, as measured by validated Risk Analysis Index (RAI), on the occurrence of postoperative complications after urologic surgeries in a national database comprised of diverse practice groups and cases. STUDY DESIGN:The National Surgical Quality Impr...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-016-1845-z

    authors: Isharwal S,Johanning JM,Dwyer JG,Schimid KK,LaGrange CA

    更新日期:2017-01-01 00:00:00

  • Challenges in urogenital tuberculosis.

    abstract:PURPOSE:For better understanding of urogenital tuberculosis (UGTB), its clinical spectrum and characteristic features need to be evaluated. MATERIALS AND METHODS:One hundred and forty-two cases of UGTB patients were analyzed retrospectively. We considered age, gender, symptoms, and diagnostic procedures. RESULTS:The ...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-019-02767-x

    authors: Kulchavenya E,Kholtobin D,Shevchenko S

    更新日期:2020-01-01 00:00:00

  • Effect of testosterone, raloxifene and estrogen replacement on the microstructure and biomechanics of metaphyseal osteoporotic bones in orchiectomized male rats.

    abstract:INTRODUCTION:Currently, osteoporosis research is rarely undertaken in males but an increase in male life expectancy in the company of hypogonadism suggests the necessity for potential therapeutic options. MATERIALS AND METHODS:In this study, the changes in bone structure under standardized testosterone- (T), raloxifen...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-009-0373-5

    authors: Stuermer EK,Sehmisch S,Tezval M,Tezval H,Rack T,Boekhoff J,Wuttke W,Herrmann TR,Seidlova-Wuttke D,Stuermer KM

    更新日期:2009-08-01 00:00:00

  • The effect of labor and/or ovariectomy on rodent continence mechanism--the neuronal changes.

    abstract::Many women develop stress urinary incontinence (SUI) after childbirth, but the exact neuronal changes are largely unknown. This study is designed to identify the neuronal changes associated with pregnancy, delivery and ovariectomy. A total of 10 virgin and 48 pregnant rats were used. Cystometry and stress/sneeze tests...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-004-0444-6

    authors: Sievert KD,Bakircioglu ME,Tsai T,Nunes L,Lue TF

    更新日期:2004-10-01 00:00:00

  • Morbidity associated with repeated transrectal high-intensity focused ultrasound treatment of localized prostate cancer.

    abstract::The aim of this cross-sectional study was to compare single with repeated high-intensity focused ultrasound (HIFU) treatment in patients with localized prostate cancer, regarding treatment-related morbidity. A number of 223 consecutive patients with localized prostate cancer were treated with HIFU. Among them, 174 (78...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-006-0107-x

    authors: Blana A,Rogenhofer S,Ganzer R,Wild PJ,Wieland WF,Walter B

    更新日期:2006-11-01 00:00:00

  • Genital skin loss: unified reconstructive approach to a heterogeneous entity.

    abstract::Genital skin loss results from a heterogeneous group of traumatic and infectious processes. Removal of all devitalized tissue is necessary prior to reconstructive surgery; hyperbaric oxygen may help in the management of necrotizing infections. Defect coverage depends more on the remaining genital skin than on the etio...

    journal_title:World journal of urology

    pub_type: 杂志文章,评审

    doi:10.1007/s003450050115

    authors: Wessells H

    更新日期:1999-04-01 00:00:00

  • 68Ga-labelled PSMA ligand HBED-CC PET/CT imaging in patients with recurrent prostate cancer.

    abstract:BACKGROUND:68Ga-PSMA Positron Emission Tomography/Computerized Tomography (PET/CT) has shown promising results for the detection of recurrent prostate cancer (RPCa). However, the diagnostic value of this method is yet to be validated. The aim of this study was to determine the influence of clinical and biochemical vari...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-018-2460-y

    authors: Akdemir EN,Tuncel M,Akyol F,Bilen CY,Baydar DE,Karabulut E,Ozen H,Caglar M

    更新日期:2019-05-01 00:00:00

  • The inhibitory effect of sacral dorsal root ganglion stimulation on nociceptive and nonnociceptive bladder reflexes in cats.

    abstract:PURPOSE:To investigate the inhibitory effects of electrical stimulation of sacral dorsal root ganglion (DRG) on bladder activity under non-nociceptive and nociceptive bladder conditions in cats. MATERIALS AND METHODS:12 cats were divided into non-nociceptive and nociceptive groups. Saline was used to distend the bladd...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-018-2198-6

    authors: Wang Z,Liao L,Deng H,Li X,Chen G

    更新日期:2018-05-01 00:00:00

  • Elderly patients aged ≥ 75 years with locally advanced prostate cancer may benefit from local treatment: a population-based propensity score-adjusted analysis.

    abstract:OBJECTIVE:To evaluate whether elderly patients aged ≥ 75 years with locally advanced prostate cancer (LAPC) may benefit from local treatment (LT). METHODS:Elderly patients aged ≥ 75 years with non-metastatic cT3-4 LAPC who were treated with LT [radical prostatectomy (RP), radiation therapy (RT)] or non-LT (NLT) were i...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-018-2389-1

    authors: Sheng W,Kirschner-Hermanns R,Zhang H

    更新日期:2019-02-01 00:00:00

  • Correction to: The natural course of pT2 prostate cancer with positive surgical margin: predicting biochemical recurrence.

    abstract::In multivariate analysis, GS of the regular prostatectomy specimen was the only statistically significant parameter for pT2R1 prostate cancer. ...

    journal_title:World journal of urology

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s00345-020-03136-9

    authors: Karl A,Buchner A,Tympner C,Kirchner T,Ganswindt U,Belka C,Ganzer R,Burger M,Eder F,Hofstädter F,Schilling D,Sievert K,Stenzl A,Scharpf M,Fend F,Dorp FV,Rübben H,Schmid K,Porres-Knoblauch D,Heidenreich A,Hangarter

    更新日期:2020-06-01 00:00:00

  • Consistent and significant improvement of nighttime voiding frequency (nocturia) with silodosin in men with LUTS suggestive of BPH: pooled analysis of three randomized, placebo-controlled, double-blind phase III studies.

    abstract:OBJECTIVES:Nocturia is prevalent and bothersome in men with lower urinary tract symptoms suggestive of BPH (LUTS/BPH). α-Adrenoceptor antagonists without subtype selectivity have inconsistently shown significant effects on nocturia in these patients. We explored the effects of the α1A-adrenoceptor subtype-selective ant...

    journal_title:World journal of urology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00345-013-1228-7

    authors: Eisenhardt A,Schneider T,Cruz F,Oelke M

    更新日期:2014-10-01 00:00:00

  • An antimicrobial prophylaxis protocol using rectal swab cultures for transrectal prostate biopsy.

    abstract:PURPOSE:To evaluate the benefit of an antimicrobial prophylaxis protocol using rectal swab cultures in patients undergoing transrectal ultrasound (TRUS)-guided prostate biopsy in our Veterans Affairs population. METHODS:Between June 1, 2013, and June 1, 2014, we implemented an antimicrobial prophylaxis protocol using ...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-015-1571-y

    authors: Summers SJ,Patel DP,Hamilton BD,Presson AP,Fisher MA,Lowrance WT,Southwick AW

    更新日期:2015-12-01 00:00:00

  • Sky is no limit for ureteroscopy: extending the indications and special circumstances.

    abstract:PURPOSE:To critically review and synthesize data of ureteroscopy (URS) in different circumstances that all urologists may encounter during everyday clinical practice, such as pregnancy, obesity, bleeding diathesis, renal stones larger than 2 cm, calyceal diverticula, and kidney malformations. METHODS:According to PRIS...

    journal_title:World journal of urology

    pub_type: 杂志文章,评审

    doi:10.1007/s00345-014-1345-y

    authors: Giusti G,Proietti S,Peschechera R,Taverna G,Sortino G,Cindolo L,Graziotti P

    更新日期:2015-02-01 00:00:00

  • Achieving the "trifecta" with open versus minimally invasive partial nephrectomy.

    abstract:INTRODUCTION:The "trifecta" is a summary measure of outcome after partial nephrectomy (PN) that encompasses three parameters: negative surgical margin, ≤ 10% decrease in post-operative estimated glomerular filtration rate (eGFR) and absence of urological complications. We assessed trifecta rates in patients undergoing ...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-020-03349-y

    authors: Ghavimi S,Saarela O,Pouliot F,Rendon RA,Finelli A,Kapoor A,Moore RB,Breau RH,Lavallee L,Lacombe L,Fairey A,Jewett M,Liu Z,Tanguay S,Black PC

    更新日期:2020-07-12 00:00:00

  • Long-term outcome of kidneys with initially poor drainage or no drainage following pyeloplasty.

    abstract::Pyeloplasty for congenital ureteropelvic junction (UPJ) obstruction enjoys a 90-95% success rate. Although treatment of the failed pyeloplasty has been addressed in the literature, management of the poorly draining or nondraining renal unit in the immediate postoperative period has not received any attention. For this...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/BF00183119

    authors: Miyamoto KK,Mesrobian HG

    更新日期:1996-01-01 00:00:00

  • Thulium fiber laser: ready to dust all urinary stone composition types?

    abstract:PURPOSE:To evaluate whether stone dust can be obtained from all prevailing stone composition types using the thulium fiber laser (TFL) for lithotripsy. Where applicable, stone dust was further characterized by morpho-constitutional analysis. METHODS:Human urinary stones were submitted to in vitro lithotripsy using a F...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-020-03217-9

    authors: Keller EX,De Coninck V,Doizi S,Daudon M,Traxer O

    更新日期:2020-05-03 00:00:00

  • Subcutaneous tunneling of the temporary testing electrode significantly improves the success rate of subchronic sacral nerve modulation (SNM).

    abstract::Sacral nerve modulation (SNM) is an effective way to treat non-neurogenic dysfunctions of pelvic organs. For over 20 years, this technique has been used for the treatment of overactive bladder, urinary retention, pelvic pain and even more recently, fecal incontinence and constipation. The objective of the study is to ...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-007-0204-5

    authors: Sievert KD,Nagele U,Pannek J,Engeler D,Kuczyk M,Stenzl A

    更新日期:2007-12-01 00:00:00

  • Association between family history of prostate cancer and positive biopsies in a Brazilian screening program.

    abstract:PURPOSE:To test the association between family history of prostate cancer (FH) and prostate cancer (PCa) risk in a large screening program in Brazil, as no conclusive study has yet investigated this. METHODS:Between 2004 and 2007, 17,569 men were screened in 231 small municipalities using mobile screening units. Posit...

    journal_title:World journal of urology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00345-012-0904-3

    authors: Muller RL,Faria EF,Carvalhal GF,Reis RB,Mauad EC,Carvalho AL,Freedland SJ

    更新日期:2013-10-01 00:00:00

  • Salvage radical prostatectomy as management of locally recurrent prostate cancer: outcomes and complications.

    abstract:PURPOSE:Management of prostate cancer following radiation therapy remains challenging, especially for younger men or those with life expectancy greater than 10 years. We outline the efficacy, safety and adequacy of radical prostatectomy for the treatment of radiorecurrent localized prostate cancer. METHODS:A systemati...

    journal_title:World journal of urology

    pub_type: 杂志文章,评审

    doi:10.1007/s00345-013-1029-z

    authors: Rosoff JS,Savage SJ,Prasad SM

    更新日期:2013-12-01 00:00:00

  • Impact of novel techniques on minimally invasive adrenal surgery: trends and outcomes from a contemporary international large series in urology.

    abstract:OBJECTIVE:To evaluate contemporary international trends in the implementation of minimally invasive adrenalectomy and to assess contemporary outcomes of different minimally invasive techniques performed at urologic centers worldwide. METHODS:A retrospective multinational multicenter study of patients who underwent min...

    journal_title:World journal of urology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00345-016-1791-9

    authors: Pavan N,Autorino R,Lee H,Porpiglia F,Sun Y,Greco F,Jeff Chueh S,Han DH,Cindolo L,Ferro M,Chen X,Branco A,Fornara P,Liao CH,Miyajima A,Kyriazis I,Puglisi M,Fiori C,Yang B,Fei G,Altieri V,Jeong BC,Berardinelli F

    更新日期:2016-10-01 00:00:00

  • Tubularized urethral replacement with unseeded matrices: what is the maximum distance for normal tissue regeneration?

    abstract:PURPOSE:Complete urethral replacement using unseeded matrices has been proposed as a possible therapy in cases of congenital or acquired anomalies producing significant defects. Tissue regeneration involves fibrin deposition, re-epithelialization, and remodeling that are limited by the size of the defect. Scar formatio...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-008-0316-6

    authors: Dorin RP,Pohl HG,De Filippo RE,Yoo JJ,Atala A

    更新日期:2008-08-01 00:00:00

  • The cardiovascular risk factors in men with lower urinary tract symptoms.

    abstract:OBJECTIVE:It has been hypothesized that endothelial dysfunction and pelvic atherosclerosis may contribute to lower urinary tract symptoms (LUTS). We assessed the relationship between cardiovascular risk factors and LUTS severity in male patients presented to urology clinic. METHODS:It is a cross-sectional study on pat...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-018-2432-2

    authors: Yee CH,Yip JSY,Cheng NMY,Kwan CH,Li KM,Teoh JYC,Chiu PKF,Wong JH,Chan ESY,Chan CK,Hou SSM,Ng CF

    更新日期:2019-04-01 00:00:00

  • Clinical and therapeutic factors associated with adverse pathological outcomes in clinically node-negative patients treated with neoadjuvant cisplatin-based chemotherapy and radical cystectomy.

    abstract:PURPOSE:Several disease characteristics have been identified as potential predictors for pathological node involvement (pN+) following radical cystectomy (RC). However, these have not been assessed in patients treated with neoadjuvant chemotherapy (NAC). We endeavored to assess factors predicting adverse pathology in c...

    journal_title:World journal of urology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00345-015-1667-4

    authors: Zargar-Shoshtari K,Zargar H,Dinney CP,Ercole CE,Sharma P,Kovac E,Grivas PD,Stephenson AJ,Shah JB,Black PC,Spiess PE

    更新日期:2016-05-01 00:00:00

  • Orthotopic urinary diversion: the Kock ileal neobladder.

    abstract::Orthotopic urinary diversion via the Kock ileal neobladder is the preferred form of bladder reconstruction in men and, now, in women undergoing cystectomy at the University of Southern California. Through June of 1993, 266 men were diverted in this fashion. There were 3 perioperative mortalities (1.1%); early complica...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/BF01836343

    authors: Elmajian DA,Stein JP,Skinner DG

    更新日期:1996-01-01 00:00:00

  • Advances in robotic surgery for pediatric ureteropelvic junction obstruction and vesicoureteral reflux: history, present, and future.

    abstract:PURPOSE:The introduction of robotic surgical technology into urological reconstruction, particularly pediatrics, has introduced new horizons for reducing the morbidity and enhancing the efficacy of surgical repair of congenital conditions in children. In reviewing the evolution of pediatric urological applications of r...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-019-02753-3

    authors: Satyanarayan A,Peters CA

    更新日期:2020-08-01 00:00:00

  • Robotic extended pyelolithotomy for treatment of renal calculi: a feasibility study.

    abstract::Percutaneous nephrolithotomy (PCNL) remains the treatment of choice for staghorn renal calculi. Many reports suggest that laparoscopy can be an alternative treatment for large renal stones. We wished to evaluate the role and feasibility of laparoscopic extended pyelolithotomy (REP) for treatment of staghorn calculi. T...

    journal_title:World journal of urology

    pub_type: 杂志文章

    doi:10.1007/s00345-006-0099-6

    authors: Badani KK,Hemal AK,Fumo M,Kaul S,Shrivastava A,Rajendram AK,Yusoff NA,Sundram M,Woo S,Peabody JO,Mohamed SR,Menon M

    更新日期:2006-06-01 00:00:00