Abstract:
:Metastasis is the cascade of events involved in the transition of a malignancy from a localized tumor to the establishment of a distant foci. In this review we define the known stages and the factors involved. The multiplicity of steps involved allows many opportunities for therapeutic intervention. Current research has focused on interruption of a step or a series of steps to limit the spread of cancer. With emphasis on the urologic malignancies, we outline the research thus far accomplished in the field of metastasis.
journal_name
World J Uroljournal_title
World journal of urologyauthors
Lawrence JA,Steeg PSdoi
10.1007/BF00186891subject
Has Abstractpub_date
1996-01-01 00:00:00pages
124-30issue
3eissn
0724-4983issn
1433-8726journal_volume
14pub_type
杂志文章,评审abstract:PURPOSE:Partial nephrectomy (PN) outcomes may be better at academic institutions than at non-academic centers. Peer-review, sub-specialized practice profile, higher individual surgeon and institutional caseload may explain this observation. To the best of our knowledge, the role of institutional academic affiliation ha...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0759-z
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to evaluate the factors affecting the lower urinary tract symptoms (LUTS) related quality of life (QoL) score. METHODS:This retrospective study analyzed 29,123 men who underwent health check-ups from January 2007 to July 2011 at a single institution. Those patients who completed th...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2052-2
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:To compare efficacy and safety between superior calyceal access and inferior calyceal access for pelvic and/or lower calyceal renal stones. METHODS:Consecutive patients presenting with Pelvic and/or inferior calyceal renal calculi were allocated to the superior calyceal access (group 1) or inferior calyceal ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03409-3
更新日期:2020-08-31 00:00:00
abstract:PURPOSE:The perioperative and oncological outcomes of laparoscopic radical nephrectomy (LRN) for T1-T2 renal cell carcinoma (RCC) are well established. We aim to determine whether LRN is a comparable alternative to open radical nephrectomy (ORN) in the treatment of T3 RCC using a matched pair analysis study design. ME...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-014-1280-y
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Numerous recent studies have shown that concomitant carcinoma in situ (CIS) can be closely associated with the prognosis of patients with bladder cancer (BCa). However, the prognostic value of CIS in BCa is still not conclusive. Hence, we performed a systematic review and meta-analysis to explore the associa...
journal_title:World journal of urology
pub_type: 杂志文章,meta分析
doi:10.1007/s00345-019-02738-2
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:Holmium laser enucleation of the prostate (HoLEP) has become a popular alternative to TURP for desobstructive prostate surgery. The prevalence of incidental prostate cancer (iPCa) during surgery varies depending on many preoperative factors. To evaluate whether the surgical procedure itself (HoLEP vs. TURP) inf...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2353-0
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of WX-G250, a chimeric monoclonal antibody that binds to carboxy anhydrase IX, combined with low-dose interferon-alpha (LD-IFNα) in patients with progressive metastatic renal cell carcinoma (mRCC). PATIENTS AND METHODS:Thirty-one patients, nephrectomized for the primary tumo...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-010-0570-2
更新日期:2011-02-01 00:00:00
abstract::Clinical epidemiology is sometimes called the basic science of clinical medicine. In terms of the pathogenesis of testicular germ cell tumors (GCTs), clinical epidemiology analyzes suspected risk factors. The present review highlights the risk factors established so far and briefly summarizes those factors currently u...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-004-0398-8
更新日期:2004-04-01 00:00:00
abstract:INTRODUCTION AND OBJECTIVES:Previous studies reported improved outcomes for bladder cancer patients who had radical cystectomy (RC) performed by surgeons and hospitals with high annual RC volumes. The objective of this study was to determine the effect of high hospital and surgeon volume on overall survival after RC fo...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-014-1457-4
更新日期:2015-09-01 00:00:00
abstract::In this prospective study a comparison of 4-versus 7-MHz transrectal ultrasonography for the detection of prostatic carcinoma is reported. A total of 150 prostates were biopsied due to suspicion of malignancy arising at either digital rectal examination, 4- and/or 7-MHz transrectal ultrasonography, or elevated serum p...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00182174
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:To compare the efficacy, safety, Patient Global Impression of Improvement (PGI-I), and complications rates after 180-W GreenLight laser (180-W GL laser) standard and anatomical photoselective vaporization (sPVP and aPVP). METHODS:Within a multi-institutional database, we identified patients who underwent sPVP ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-017-2106-5
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:Obesity may be a risk factor for kidney donors to develop reduced renal function. The Framingham heart study suggested that visceral adipose tissue (VAT) confers a more adverse metabolic profile compared with subcutaneous adipose tissue (SAT). Asians tend to have a higher VAT composition and it is unclear ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2566-2
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVES:To investigate pathological and oncological outcomes of obese patients who underwent robot-assisted radical prostatectomy (RARP) compared with laparoscopic radical prostatectomy (LRP) or open retropubic radical prostatectomy (RRP) since limited comparative data exist with regard to oncological and survival o...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-014-1326-1
更新日期:2015-03-01 00:00:00
abstract:PURPOSE:To test the association between family history of prostate cancer (FH) and prostate cancer (PCa) risk in a large screening program in Brazil, as no conclusive study has yet investigated this. METHODS:Between 2004 and 2007, 17,569 men were screened in 231 small municipalities using mobile screening units. Posit...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-012-0904-3
更新日期:2013-10-01 00:00:00
abstract::The thin mucus or glycosaminoglycan layer of the bladder may be implicated in the pathogenesis of many bladder disease states. We have developed a specific antimucus, antisera stabilization technique to study the ultrastructural morphological appearance of the layer in both normal and abnormal bladders that should pro...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00182045
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:68Ga-PSMA Positron Emission Tomography/Computerized Tomography (PET/CT) has shown promising results for the detection of recurrent prostate cancer (RPCa). However, the diagnostic value of this method is yet to be validated. The aim of this study was to determine the influence of clinical and biochemical vari...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2460-y
更新日期:2019-05-01 00:00:00
abstract::Expression and overexpression of the epidermal growth factor receptor (EGFR) have been described in several solid tumors including bladder, breast, colorectal, NSCLC, prostate, and ovarian cancers. In addition to gene amplification, point mutations within the kinase domain also occur. Previous reports indicate that th...
journal_title:World journal of urology
pub_type: 杂志文章,收录出版
doi:10.1007/s00345-007-0202-7
更新日期:2007-12-01 00:00:00
abstract:PURPOSE:To explore the role of prostate biopsy core length on prediction of index tumor clinical significance and localization on radical prostatectomy (RP) and time to recurrence, hypothesizing 10-, 10-12-, or > 12-mm minimum core as potential biopsy quality control. METHODS:Assessed 2424 prostate biopsy cores and co...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2242-6
更新日期:2018-07-01 00:00:00
abstract::The aim of this project was to evaluate the ice-water test as a predictor of the response to intradetrusor botulinum toxin injection in patients with neurogenic detrusor overactivity. We retrospectively evaluated the urodynamic parameters in 22 patients with neurogenic bladder dysfunction and positive ice-water test. ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-007-0208-1
更新日期:2007-12-01 00:00:00
abstract::The purpose of the present study was to examine the outcome profiles of a large number of patients with locally advanced adenocarcinoma of the prostate following radical perineal prostatectomy (RPP) for clinically organ-confined disease. Of 1662 men who underwent RPP performed by a single surgeon between January 1972 ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s003459900100
更新日期:2000-06-01 00:00:00
abstract:PURPOSE:To compare the impact of 18F-sodium-fluoride (NaF) PET/CT, 18F-fluorocholine (FCH) PET/CT and diffusion-weighted whole-body MRI (DW-MRI) on the management of patients with prostate cancer (PCa) suspicious for distant metastasis. METHODS:Prostate cancer patients were prospectively included between December 2011...
journal_title:World journal of urology
pub_type: 杂志文章,多中心研究
doi:10.1007/s00345-018-2547-5
更新日期:2019-08-01 00:00:00
abstract::The surgical complications encountered in 478 patients who underwent primary retroperitoneal lymph-node dissection for clinical stage A and B nonseminomatous testicular cancer during the period ranging from 1982 to 1992 were reviewed. There were 54 complications in 51 patients (10.6%), and there was no surgery-related...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/BF00192272
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:This study aimed to identify non-neoplastic pathologic changes in partial nephrectomy specimens of patients without a known history of medical comorbidities. Routine analysis of this tissue may allow the clinician to identify subclinical renal disease. METHODS:We retrospectively reviewed our database of patien...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-011-0720-1
更新日期:2013-08-01 00:00:00
abstract:PURPOSE:To evaluate the present human-based evidence that diet is related to the risk and outcome of prostate cancer. METHODS:Review of major case-control and cohort studies, and experimental trials evaluating the effect of diet or dietary constituents on the risk of prostate cancer. RESULTS:Although non-experimental...
journal_title:World journal of urology
pub_type: 杂志文章,评审
doi:10.1007/s00345-011-0810-0
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:Patients and their families utilize online resources when dealing with a diagnosis of bladder cancer. Many patients have questions regarding clinical management options. Online research forums may help researchers and providers identify research areas of interest. Our objective was to review online forums and i...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-018-2479-0
更新日期:2019-06-01 00:00:00
abstract:PURPOSE:To compare the ability of Prostate Health Index (PHI) to diagnose csPCa, with that of total PSA, PSA density (PSAD) and the multiparametric magnetic resonance (mpMRI) of the prostate. METHODS:We analysed a group of 395 men planned for a prostate biopsy who underwent a mpMRI of the prostate evaluated using the ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-020-03397-4
更新日期:2020-08-06 00:00:00
abstract:OBJECTIVE:To provide appropriate evidence for treatment planning of patients with an impacted proximal ureteral stones ≥1.5 cm in size, by analyzing the therapeutic outcomes for those undergoing minimally invasive percutaneous antegrade ureterolithotripsy and retrograde ureterolithotripsy. PATIENTS AND METHODS:From Se...
journal_title:World journal of urology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00345-013-1026-2
更新日期:2013-12-01 00:00:00
abstract:PURPOSE:To assess the performance of EAU risk classification in PCa patients according to the biopsy pathway (standard versus MRI guided) and to develop a new, more accurate, targeted biopsy (TB)-based classification. MATERIALS AND METHODS:We included 1345 patients consecutively operated by radical prostatectomy (RP) ...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-019-03053-6
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Recent lung cancer data have shown an association of XPA-210, a key peptide of thymidine kinase, with advanced disease. We thus assessed its proliferation status in primary (M0) and metastatic (M1) renal cell carcinoma (RCC). METHODS:Paraffin slides from 30 patients (mean age: 61.2 years; range: 42-84) with cl...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s00345-010-0621-8
更新日期:2011-12-01 00:00:00
abstract::The effects of pelvic floor muscle contraction on rectal and vesical function were studied in 19 healthy volunteers with the aim of shedding light on some of the hitherto vague aspects of the mechanisms involved in micturition and defecation and their disorders. Rectal and vesical pressures were recorded during pubore...
journal_title:World journal of urology
pub_type: 杂志文章
doi:10.1007/s003450100218
更新日期:2001-08-01 00:00:00