Current and emerging pharmacological therapy for non-alcoholic fatty liver disease.

abstract：:A 83-year-old woman was admitted to our hospital because of intermittent abdominal colicky pain and vomiting for 26 h. The pain localized over the periumbilical area with radiation along the medial side of the thigh. Computed tomography scan with three-dimensional reconstruction revealed a loop of small bowel protrudi...

journal_title：World journal of gastroenterology

authors： Zhang H,Cong JC,Chen CS

更新日期：2010-01-07 00:00:00

abstract：AIM:To investigate the feasibility of detecting methylated fecal DNA as a screening tool for colorectal carcinoma (CRC) and precancerous lesions. METHODS:Methylated secreted frizzled-related protein gene 2 (SFRP2), hyperplastic polyposis protein gene (HPP1) and O6-methylguanine-DNA methyltransferase gene (MGMT) in sto...

journal_title：World journal of gastroenterology

authors： Huang ZH,Li LH,Yang F,Wang JF

更新日期：2007-02-14 00:00:00

abstract：AIM:To evaluate whether alcohol dehydrogenase-1B (ADH1B) His47Arg and aldehyde dehydrogenase-2 (ALDH2) Glu487Lys polymorphism is involved in the esophageal squamous cell carcinoma (ESCC) risk in Chinese Han population. METHODS:Seven studies of ADH1B and ALDH2 genotypes in Chinese Han population in 1450 cases and 2459 ...

journal_title：World journal of gastroenterology

authors： Zhang GH,Mai RQ,Huang B

更新日期：2010-12-21 00:00:00

abstract：AIM:To investigate the clinicopathologic features of patients with extra-gastrointestinal stromal tumors (EGISTs) in South Korea. METHODS:A total of 51 patients with an EGIST were identified. The clinicopathologic features, including sex, age, location, tumor size, histology, mitotic rate, immunohistochemical features...

journal_title：World journal of gastroenterology

authors： Yi JH,Park BB,Kang JH,Hwang IG,Shin DB,Sym SJ,Ahn HK,Lee SI,Lim DH,Park KW,Won YW,Lim SH,Park SH

更新日期：2015-02-14 00:00:00

abstract：:Patients with esophageal cancer often require esophagectomy with esophagogastrostomy. However, the incidence of complications, such as hemorrhage, during operations for esophageal cancer is high, even with minimally invasive surgery. Without the appropriate interventions, the risk of major intraoperative and postopera...

journal_title：World journal of gastroenterology

authors： Zhang GF,Chai Y,Li WS,Huang LS,Shen G

更新日期：2014-09-21 00:00:00

abstract：AIM:To evaluate of scoring system in predicting choledocholithiasis in selective intraoperative cholangiography (IOC) during laparoscopic cholecystectomy (LC). METHODS:The scoring system of predicting choledocholithiasis was developed during the retrospective study in 264 cases, and was tested in 184 to evaluate its p...

journal_title：World journal of gastroenterology

authors： Sun XD,Cai XY,Li JD,Cai XJ,Mu YP,Wu JM

更新日期：2003-04-01 00:00:00

abstract：:Bowel preparation is a core issue in colonoscopy, as it is closely related to the quality of the procedure. Patients often find that bowel preparation is the most unpleasant part of the examination. It is widely accepted that the quality of cleansing must be excellent to facilitate detecting neoplastic lesions. In spi...

journal_title：World journal of gastroenterology

authors： Parra-Blanco A,Ruiz A,Alvarez-Lobos M,Amorós A,Gana JC,Ibáñez P,Ono A,Fujii T

更新日期：2014-12-21 00:00:00

abstract：AIM:To investigate the prevalence and characteristics of uninvestigated dyspepsia among college students in Zhejiang Province. METHODS:Young adult students attending undergraduate (within the 4-year program) and graduate (only first-year students) colleges in Zhejiang Province were recruited between November 2010 and ...

journal_title：World journal of gastroenterology

authors： Li M,Lu B,Chu L,Zhou H,Chen MY

更新日期：2014-04-07 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) has become a major cause of chronic liver disease. The Chinese herbal medicine (CHM) Dachaihu decoction (DCHD) has been proved to treat NAFLD with good efficacy in previous studies. Based on the TCM principle of formula formation, we divided DCHD into soothing liver ...

journal_title：World journal of gastroenterology

authors： Yang JM,Sun Y,Wang M,Zhang XL,Zhang SJ,Gao YS,Chen L,Wu MY,Zhou L,Zhou YM,Wang Y,Zheng FJ,Li YH

更新日期：2019-09-14 00:00:00

abstract：:Because of the low prevalence of non-ampullary duodenal epithelial tumors (NADETs), standardized clinical management of sporadic superficial NADETs, including diagnosis, treatment, and follow-up, has not yet been established. Retrospective studies have revealed certain endoscopic findings suggestive of malignancy. Duo...

journal_title：World journal of gastroenterology

authors： Kakushima N,Kanemoto H,Tanaka M,Takizawa K,Ono H

更新日期：2014-09-21 00:00:00

abstract：:Alcoholic fatty liver disease (AFLD), a potentially pathologic condition, can progress to steatohepatitis, fibrosis, and cirrhosis, leading to an increased probability of hepatic failure and death. Alcohol induces fatty liver by increasing the ratio of reduced form of nicotinamide adenine dinucleotide to oxidized form...

journal_title：World journal of gastroenterology

authors： Liu J

更新日期：2014-10-28 00:00:00

abstract：AIM:To investigate the efficacy and side effects of the combined therapy of oxaliplatin and capecitabine in patients with metastatic esophageal squamous cell cancer (ESCC) and the survival of the patients. METHODS:Sixty-four patients (median age of 63 years) with histological or cytological confirmation of ESCC receiv...

journal_title：World journal of gastroenterology

authors： Qin TJ,An GL,Zhao XH,Tian F,Li XH,Lian JW,Pan BR,Gu SZ

更新日期：2009-02-21 00:00:00

abstract：AIM:To identify the incidence and etiology of anemia after gastrectomy in patients with long-term follow-up after gastrectomy for early gastric cancer. METHODS:The medical records of those patients with early gastric adenocarcinoma who underwent curative gastrectomy between January 2006 and October 2007 were reviewed....

journal_title：World journal of gastroenterology

authors： Lim CH,Kim SW,Kim WC,Kim JS,Cho YK,Park JM,Lee IS,Choi MG,Song KY,Jeon HM,Park CH

更新日期：2012-11-14 00:00:00

abstract：:The goal of therapy in chronic hepatitis C virus (HCV) infection is sustained virological response (SVR) which reflects HCV eradication. Treatment against HCV has dramatically improved with the recent availability of direct-acting antivirals (DAAs) including sofosbuvir, simeprevir, daclatasvir, ledipasvir/sofosbuvir, ...

journal_title：World journal of gastroenterology

authors： Cholongitas E,Pipili C,Papatheodoridis G

更新日期：2015-08-28 00:00:00

abstract：AIM:To determine the pattern and distribution of colonic diverticulosis in Thai adults. METHODS:A review of the computerized radiology database for double contrast barium enema (DCBE) in Thai adults was performed at the Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. Incomplete studies and...

journal_title：World journal of gastroenterology

authors： Lohsiriwat V,Suthikeeree W

更新日期：2013-12-14 00:00:00

abstract：AIM:To identify predictors for synchronous liver metastasis from resectable pancreatic ductal adenocarcinoma (PDAC) and assess unresectability of synchronous liver metastasis. METHODS:Retrospective records of PDAC patients with synchronous liver metastasis who underwent simultaneous resections of primary PDAC and sync...

journal_title：World journal of gastroenterology

authors： Shi HJ,Jin C,Fu DL

更新日期：2016-12-07 00:00:00

abstract：AIM:To investigate retrospectively the long-term effect of endoscopic sphincterotomy (ES) including exocrine pancreatic function in patients with stenosis of ampulla of Vater. METHODS:After diagnostic endoscopic retrograde cholangiopancreatography (ERCP) and ES because of stenosis of the ampulla of Vater (SOD Type I),...

journal_title：World journal of gastroenterology

authors： Ewald N,Marzeion AM,Bretzel RG,Kloer HU,Hardt PD

更新日期：2007-02-14 00:00:00

abstract：AIM:To investigate the reasons for the occurrence of the pink-color sign of iodine-unstained lesions. METHODS:In chromoendoscopy, the pink-color sign of iodine-unstained lesions is recognized as useful for the diagnosis of esophageal squamous cell carcinoma. Patients with superficial esophageal neoplasms treated by en...

journal_title：World journal of gastroenterology

authors： Ishihara R,Kanzaki H,Iishi H,Nagai K,Matsui F,Yamashina T,Matsuura N,Ito T,Fujii M,Yamamoto S,Hanaoka N,Takeuchi Y,Higashino K,Uedo N,Tatsuta M,Tomita Y,Ishiguro S

更新日期：2013-07-21 00:00:00

abstract：:Penicillium marneffei (P. marneffei) infection usually occurs with skin, bone marrow, lung or hepatic involvement. However, no cases of P. marneffei infection with chylous ascites have been reported thus far. In this report, we describe the first case of acquired immune deficiency syndrome (AIDS) which has been compli...

journal_title：World journal of gastroenterology

authors： Shen YZ,Wang ZY,Lu HZ

更新日期：2012-10-07 00:00:00

abstract：:Epidemiological and clinical data point to a close association between chronic hepatitis B virus infection or chronic hepatitis C virus infection and development of hepatocellular carcinoma (HCC). HCC develops over several decades and is associated with fibrosis. This sequence suggests that persistent viral infection ...

journal_title：World journal of gastroenterology

authors： Murata M,Yoshida K,Yamaguchi T,Matsuzaki K

更新日期：2014-11-07 00:00:00

abstract：:Functional gastrointestinal disorders (FGID) are heterogeneous disorders with a variety of clinical manifestations, primarily defined by signs and symptoms rather than a definite underlying cause. Their pathophysiology remains obscure and, although it is expected to differ according to the specific FGID, disruptions i...

journal_title：World journal of gastroenterology

authors： Koutouratsas T,Kalli T,Karamanolis G,Gazouli M

更新日期：2019-02-07 00:00:00

abstract：AIM:To evaluate the optimal intervention point of a selective cyclooxygenase-2 (COX-2) inhibitor, celecoxib, for inhibiting Helicobacter pylori (H. pylori)-associated gastric carcinogenesis in Mongolian gerbils (MGs). METHODS:One hundred and twelve MGs were divided into six groups (A-F). One hundred gerbils were inocu...

journal_title：World journal of gastroenterology

authors： Kuo CH,Hu HM,Tsai PY,Wu IC,Yang SF,Chang LL,Wang JY,Jan CM,Wang WM,Wu DC

更新日期：2009-10-21 00:00:00

abstract：AIM:To evaluate the long-term efficacy of endoscopic resection (ER) for small (≤ 4.0 cm) gastric gastrointestinal stromal tumors (GISTs) originating from the muscularis propria layer. METHODS:Between June 2005 and February 2015, we retrospectively analyzed 229 consecutive patients with gastric MP-GISTs who underwent E...

journal_title：World journal of gastroenterology

authors： Zhang Y,Mao XL,Zhou XB,Yang H,Zhu LH,Chen G,Ye LP

更新日期：2018-07-21 00:00:00

abstract：:Achalasia cardia is one of the common causes of motor dysphagia. Though the disease was first described more than 300 years ago, exact pathogenesis of this condition still remains enigmatic. Pathophysiologically, achalasia cardia is caused by loss of inhibitory ganglion in the myenteric plexus of the esophagus. In the...

journal_title：World journal of gastroenterology

authors： Ghoshal UC,Daschakraborty SB,Singh R

更新日期：2012-06-28 00:00:00

abstract：AIM:To analyze the modulation of gene expression profile associated with inhibition of liver regeneration in hepatitis B X (HBx)-expressing transgenic mice. METHODS:Microarray technology was performed on liver tissue obtained from 4 control (LacZ) and 4 transgenic mice (HBx-LacZ), 48 h after partial hepatectomy. The s...

journal_title：World journal of gastroenterology

authors： Sidorkiewicz M,Jais JP,Tralhao G,Morosan S,Giannini C,Brezillon N,Soussan P,Delpuech O,Kremsdorf D

更新日期：2008-01-28 00:00:00

abstract：AIM:To study the effects of cortactin on the tumor biology of SGC-7901 cells and identify the mechanism involved in the process. METHODS:Cell lines in which cortactin was stably overexpressed or knocked down as well as the respective control cell lines were established by standard molecular methods. The effects of cor...

journal_title：World journal of gastroenterology

authors： Wei J,Zhao ZX,Li Y,Zhou ZQ,You TG

更新日期：2014-03-28 00:00:00

abstract：AIM:To investigate the accuracy of serum alanine aminotransferase (ALT) in diagnosing lamivudine resistance and factors that contributed to abnormal serum ALT. METHODS:This was a retrospective study of chronic hepatitis B patients on lamivudine therapy who were followed for 3-mo with liver function tests and hepatitis...

journal_title：World journal of gastroenterology

authors： Lim LG,Aung MO,Seet BL,Tan C,Dan YY,Lee YM,Sutedja DS,Fernandes M,Lee GH,Koay E,Lim SG

更新日期：2010-10-07 00:00:00

abstract：:One 63-year-old woman, who presented with cholestatic jaundice due to common bile duct compression produced by primary retroperitoneal fibrosis, is studied. The patient was operated six years ago because of hydronephrosis, when the disease was first diagnosed. Magnetic resonance cholangiopancreatography (MRCP) reveale...

journal_title：World journal of gastroenterology

authors： Zhao MF,Tian Y,Guo KJ,Ma ZG,Liao HH

更新日期：2004-10-15 00:00:00

abstract：:A 57-year-old man consulted a local hospital because of a persistent slight fever. At the age of 37 years he was diagnosed having B-type hepatitis, but left the liver dysfunction untreated. Twenty years later, he was diagnosed having chronic hepatitis B, hepatocellular carcinoma (HCC) and macrocytic anemia, and referr...

journal_title：World journal of gastroenterology

authors： Okada T,Kubota K,Kita J,Kato M,Sawada T

更新日期：2007-08-28 00:00:00

abstract：AIM:To assess the efficiency of endoscopic trans-esophageal submucosal tunneling surgery (EESTS) technique for diseases located around the aorta ventralis. METHODS:Nine pigs were assigned to EESTs. The procedures were as follows: First, a long esophageal submucosal tunnel was established. Second, full-thickness myotom...

journal_title：World journal of gastroenterology

authors： Xiong Y,Chen QQ,Chai NL,Jiao SC,Ling Hu EQ

更新日期：2019-01-07 00:00:00