Interferon-free regimens for the treatment of hepatitis C virus in liver transplant candidates or recipients.

abstract：AIM:To determine risk factors associated with hepatitis C virus (HCV) treatment failure after direct acting antivirals in patients with complex treatment histories. METHODS:All HCV mono-infected patients who received treatment at our institution were queried. Analysis was restricted to patients who previously failed t...

journal_title：World journal of gastroenterology

authors： Hartman J,Bichoupan K,Patel N,Chekuri S,Harty A,Dieterich D,Perumalswami P,Branch AD

更新日期：2015-11-21 00:00:00

abstract：AIM:To determine the in vivo and in vivo effects of cysteamine (CS) on expression and activity of H(+)-K(+)-ATPase of gastric mucosal cells in weaning piglets. METHODS:Eighteen litters of newborn Xinhuai piglets were employed in the in vivo experiment and allocated to control and treatment groups. From 12 d of age (D1...

journal_title：World journal of gastroenterology

authors： Shi ZM,Du GM,Wei XH,Zhang L,Chen J,Zhao RQ

更新日期：2005-11-14 00:00:00

abstract：:Pancreatic cancer is a leading cause of cancer mortality and the incidence of this disease is expected to continue increasing. While patients with pancreatic cancer have traditionally faced a dismal prognosis, over the past several years various advances in diagnosis and treatment have begun to positively impact this ...

journal_title：World journal of gastroenterology

authors： Mohammed S,Van Buren G 2nd,Fisher WE

更新日期：2014-07-28 00:00:00

abstract：:Helicobacter pylori (H pylori) infection is the main cause of gastritis, gastroduodenal ulcer disease, and gastric cancer. After more than 20 years of experience in H pylori treatment, in my opinion, the ideal regimen to treat this infection is still to be found. Currently, apart from having to know first-line eradica...

journal_title：World journal of gastroenterology

authors： Gisbert JP

更新日期：2008-09-21 00:00:00

abstract：:The origin of inflammatory bowel disease is unknown. Attempts have been made to isolate a microorganism that could explain the onset of inflammation, but no pathological agent has ever been identified. Johne's disease is a granulomatous chronic enteritis of cattle and sheep caused by Mycobacterium avium subspecies par...

journal_title：World journal of gastroenterology

authors： Liverani E,Scaioli E,Cardamone C,Dal Monte P,Belluzzi A

更新日期：2014-09-28 00:00:00

abstract：:Gastric cancer is the second leading cause of cancer mortality worldwide. The diagnosis of gastric cancer has been significantly improved with the broad availability of gastrointestinal endoscopy. Effective technologies for accurate staging and quantitative evaluation are still in demand to merit reasonable treatment ...

journal_title：World journal of gastroenterology

authors： Wu CX,Zhu ZH

更新日期：2014-04-28 00:00:00

abstract：:AIM:To clone core gene cDNA of Chinese hepatitis C virus (HCV) into eukaryotic expression vector cosmid pTM3 and to express HCV core antigen in HepG2 cells.METHODS:Core gene cDNA of HCV was introduced into eukaryotic expression vector cosmid pTM3.Using vaccinia virus/bacteriophage T7 hybrid expression system, HepG2 ce...

journal_title：World journal of gastroenterology

authors： Jiang RL,Lu QS,Luo KX

更新日期：2000-04-01 00:00:00

abstract：AIM:To assess NY-ESO-1 expression in a cohort of esophageal adenocarcinomas. METHODS:A retrospective search of our tissue archive for esophageal resection specimens containing esophageal adenocarcinoma was performed, for cases which had previously been reported for diagnostic purposes, using the systematised nomenclat...

journal_title：World journal of gastroenterology

authors： Hayes SJ,Hng KN,Clark P,Thistlethwaite F,Hawkins RE,Ang Y

更新日期：2014-04-14 00:00:00

abstract：:Laparoscopic gastrectomy has been widely accepted as a standard alternative for the treatment of early-stage gastric adenocarcinoma because of its favorable short-term outcomes. Although controversies exist, such as establishing clear indications, proper preoperative staging, and oncologic safety, experienced surgeons...

journal_title：World journal of gastroenterology

authors： Son T,Hyung WJ

更新日期：2016-01-14 00:00:00

abstract：AIM:To investigate the underlying molecular mechanisms of miR-451 to inhibit proliferation of esophageal carcinoma cell line EC9706. METHODS:Assays for cell growth, apoptosis and invasion were used to evaluate the effects of miR-451 expression on EC cells. Luciferase reporter and Western blot assays were used to test ...

journal_title：World journal of gastroenterology

authors： Zang WQ,Yang X,Wang T,Wang YY,Du YW,Chen XN,Li M,Zhao GQ

更新日期：2015-05-21 00:00:00

abstract：:Poorly differentiated endocrine carcinoma (PDEC) of the pancreas is a rare and aggressive tumor. First-line treatment is commonly a combination of etoposide and cisplatin, but there is no consensus regarding further treatment recommendations. In this report, we describe a case of pancreatic PDEC treated with gemcitabi...

journal_title：World journal of gastroenterology

authors： Nakazuru S,Yoshio T,Suemura S,Itoh M,Araki M,Yoshioka C,Ohta M,Sueyoshi Y,Ohta T,Hasegawa H,Morita K,Toyama T,Kuzushita N,Kodama Y,Mano M,Mita E

更新日期：2010-08-14 00:00:00

abstract：AIM:To explore the influence of polymorphisms in genes encoding for the chemokines Stromal cell-Derived Factor-1 (SDF-1)/CXCL12 and Monocyte Chemotactic Protein-1 (MCP-1)/CCL2, or for the chemokine receptor CCR5 on the risks of liver-related death and hepatocellular carcinoma (HCC) occurrence in hepatitis C virus (HCV)...

journal_title：World journal of gastroenterology

authors： Nahon P,Sutton A,Rufat P,Simon C,Trinchet JC,Gattegno L,Beaugrand M,Charnaux N

更新日期：2008-02-07 00:00:00

abstract：AIM:To investigate the feasibility of detecting methylated fecal DNA as a screening tool for colorectal carcinoma (CRC) and precancerous lesions. METHODS:Methylated secreted frizzled-related protein gene 2 (SFRP2), hyperplastic polyposis protein gene (HPP1) and O6-methylguanine-DNA methyltransferase gene (MGMT) in sto...

journal_title：World journal of gastroenterology

authors： Huang ZH,Li LH,Yang F,Wang JF

更新日期：2007-02-14 00:00:00

abstract：AIM:To prospectively investigate the effectiveness and patient's tolerance of two low-cost bowel cleansing preparation protocols based on magnesium citrate only or the combination of magnesium citrate and senna. METHODS:A total of 342 patients who were referred for colonoscopy underwent a colon cleansing protocol with...

journal_title：World journal of gastroenterology

authors： Vradelis S,Kalaitzakis E,Sharifi Y,Buchel O,Keshav S,Chapman RW,Braden B

更新日期：2009-04-14 00:00:00

abstract：:Recent advances in techniques of therapeutic endoscopy for stomach neoplasms are rapidly achieved. One of the major topics in this field is endoscopic submucosal dissection (ESD). ESD is a new endoscopic technique using cutting devices to remove the tumor by the following three steps: injecting fluid into the submucos...

journal_title：World journal of gastroenterology

authors： Fujishiro M

更新日期：2006-08-28 00:00:00

abstract：:The patient with inflammatory bowel disease will be predisposed to numerous infections due their immune status. It is therefore important to understand the immune and serologic status at diagnosis and to put the patient into an adapted vaccination program. This program would be applied differently according to two pat...

journal_title：World journal of gastroenterology

authors： Sánchez-Tembleque MD,Corella C,Pérez-Calle JL

更新日期：2013-03-07 00:00:00

abstract：:Chronic intestinal pseudo-obstruction (CIPO) is a rare disease due to a severe gastrointestinal motility disorder which may mimic, on both clinical and radiological grounds, mechanical obstruction. We report a case of a 26-year-old woman who presented to our institution for plain abdominal radiography for referred lon...

journal_title：World journal of gastroenterology

authors： Camera L,Calabrese M,Sarnelli G,Longobardi M,Rocco A,Cuomo R,Salvatore M

更新日期：2011-06-28 00:00:00

abstract：BACKGROUND:At our academic tertiary care medical center, we have noted patients referred for endoscopic retrograde cholangiopancreatography (ERCP) who increasingly require advanced cannulation techniques. This trend is noted despite increased endoscopist experience and annual ERCP volume over the same period. AIM:To e...

journal_title：World journal of gastroenterology

authors： Barakat MT,Girotra M,Thosani N,Kothari S,Banerjee S

更新日期：2020-11-07 00:00:00

abstract：:Acute pancreatitis is one of the most common diseases in the everyday's practise of gastroenterologists and surgeons. However, the physicians' therapeutic armamentarium is very limited. The present letter to the editor briefly describes the recent evidence from the literature with the aim to optimize a conservative ma...

journal_title：World journal of gastroenterology

authors： Petrov MS

更新日期：2008-10-14 00:00:00

abstract：AIM:To determine the prognostic significance of isolated tumor cells (ITCs) and lymph node micrometastases in gastric cancer. METHODS:Hematoxylin and eosin-stained slides of lymph node dissections of 632 consecutive gastric cancers were reviewed. Cytokeratin immunostaining was performed in 280 node-negative cases and ...

journal_title：World journal of gastroenterology

authors： Lee HS,Kim MA,Yang HK,Lee BL,Kim WH

更新日期：2005-10-14 00:00:00

abstract：:Biodegradable stents (BDSs) are an attractive option to avoid ongoing dilation or surgery in patients with benign stenoses of the small and large intestines. The experience with the currently the only BDS for endoscopic placement, made of Poly-dioxanone, have shown promising results. However some aspects should be imp...

journal_title：World journal of gastroenterology

authors： Lorenzo-Zúñiga V,Moreno-de-Vega V,Marín I,Boix J

更新日期：2014-03-07 00:00:00

abstract：BACKGROUND:Conventionally, the low luminous intensity, low image resolution, and difficulty in operation have been reported with the ultrathin endoscope. However, it has markedly advanced recently. The improvement of the diagnostic ability is expected. AIM:To compare the early gastric cancer diagnostic ability of an u...

journal_title：World journal of gastroenterology

authors： Suzuki T,Kitagawa Y,Nankinzan R,Yamaguchi T

更新日期：2019-03-21 00:00:00

abstract：AIM:To determine if liver stiffness (LS) measurements by means of transient elastography (TE) correlate with the presence of significant esophageal varices (EV) and if they can predict the occurrence of variceal bleeding. METHODS:We studied 1000 cases of liver cirrhosis divided into 2 groups: patients without EV or wi...

journal_title：World journal of gastroenterology

authors： Sporea I,Raţiu I,Sirli R,Popescu A,Bota S

更新日期：2011-05-07 00:00:00

abstract：AIM:Over 90% of drugs are metabolized by the cytochrome P-450 (CYP) family of liver isoenzymes. The most important enzymes are CYP1A2, 3A4, 2C9/19, 2D6 and 2E1. Although CYP2D6 accounts for <2% of the total CYP liver enzyme content, it mediates metabolism in almost 25% of drugs. In order to study its enzymatic activity...

journal_title：World journal of gastroenterology

authors： Zhuge J,Yu YN,Wu XD

更新日期：2004-01-15 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common primary cancers in the world. Surgery is the gold standard for treatment of patients with HCC. Recurrence and metastasis are the major obstacles to further improve the prognosis of HCC. Most recurrences are intrahepatic. However, 30% of the recurrences are extra...

journal_title：World journal of gastroenterology

authors： Sun L,Guan YS,Pan WM,Chen GB,Luo ZM,Wu H

更新日期：2007-10-28 00:00:00

abstract：AIM:To determine the utility of endoscopic ultrasound-guided biliary drainage (EUS-BD) with a fully covered self-expandable metal stent for managing malignant biliary stricture. METHODS:We collected data from 13 patients who presented with malignant biliary obstruction and underwent EUS-BD with a nitinol fully covered...

journal_title：World journal of gastroenterology

authors： Kim TH,Kim SH,Oh HJ,Sohn YW,Lee SO

更新日期：2012-05-28 00:00:00

abstract：AIM:To evaluate the outcome of chronic hepatitis B (CHB) in children with or without malignancies. METHODS:Twenty four children (15 boys and 9 girls) with malignancies, followed up by the pediatric gastroenterology outpatient clinic for CHB between January 2000 and December 2013, were enrolled in the study (Group 1). ...

journal_title：World journal of gastroenterology

authors： Usta M,Urgancı N,Yıldırmak ZY,Dogan Vural S

更新日期：2015-02-21 00:00:00

abstract：AIM:To evaluate whether intratumoral injection of liposome-endostatin complexes could enhance the antitumor efficacy of radiation therapy in human liver carcinoma (BEL7402) model. METHODS:Recombinant plasmid pcDNA3.End was transfected into human liver carcinoma cell line (BEL7402) with lipofectamine to produce conditi...

journal_title：World journal of gastroenterology

authors： Zheng AQ,Song XR,Yu JM,Wei L,Wang XW

更新日期：2005-07-28 00:00:00

abstract：AIM:To investigate and compare the hepatogenic transdifferentiation of adipose tissue-derived stem cells (ADSC) and bone marrow-derived mesenchymal stem cells (BMSC) in vitro. Transdifferentiation of BMSC into hepatic cells in vivo has been described. Adipose tissue represents an accessible source of ADSC, with similar...

journal_title：World journal of gastroenterology

authors： Taléns-Visconti R,Bonora A,Jover R,Mirabet V,Carbonell F,Castell JV,Gómez-Lechón MJ

更新日期：2006-09-28 00:00:00

abstract：AIM:To evaluate the feasibility of using multiphoton microscopy (MPM) to assess a tumor regression grading (TRG) system. METHODS:Fresh specimens from seven patients with colorectal carcinoma undergoing neoadjuvant radiochemotherapy at the Fujian Medical University Union Hospital were obtained immediately after proctec...

journal_title：World journal of gastroenterology

authors： Li LH,Chen ZF,Wang XF,Zhuo SM,Li HS,Jiang WZ,Guan GX,Chen JX

更新日期：2015-04-14 00:00:00